KEGG   Homo sapiens (human): 1591
Entry
1591              CDS       T01001                                 
Symbol
CYP24A1, CP24, CYP24, HCAI, HCINF1, P450-CC24
Name
(RefSeq) cytochrome P450 family 24 subfamily A member 1
  KO
K07436  vitamin D3 24-hydroxylase [EC:1.14.15.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00100  Steroid biosynthesis
hsa01100  Metabolic pathways
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa05206  MicroRNAs in cancer
Disease
H01371  Hypercalcemia infantile
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    1591 (CYP24A1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    1591 (CYP24A1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    1591 (CYP24A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hsa00199]
    1591 (CYP24A1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.16  vitamin D3 24-hydroxylase
     1591 (CYP24A1)
Cytochrome P450 [BR:hsa00199]
 Cytochrome P450, animal type
  CYP24 family
   1591 (CYP24A1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 1591
NCBI-ProteinID: NP_000773
OMIM: 126065
HGNC: 2602
Ensembl: ENSG00000019186
UniProt: Q07973
LinkDB
Position
20:complement(54143538..54173986)
AA seq 514 aa
MSSPISKSRSLAAFLQQLRSPRQPPRLVTSTAYTSPQPREVPVCPLTAGGETQNAAALPG
PTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEALYR
TESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKLDNKIN
EVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIM
AIKTMMSTFGRMMVTPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYSQQPSAD
FLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL
PENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQ
VLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIV
RKYDIQATDNEPVEMLHSGTLVPSRELPIAFCQR
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgagctcccccatcagcaagagccgctcgcttgccgccttcctgcagcagctgcgcagt
ccgaggcagcccccgagactggtgacatctacggcgtacacgtcccctcagccgcgagag
gtgccagtctgcccgctgacagctggtggcgagactcagaacgcggccgccctgccgggc
cccaccagctggccactgctgggcagcctgctgcagattctctggaaagggggtctcaag
aaacagcacgacaccctggtggagtaccacaagaagtatggcaagattttccgcatgaag
ttgggttcctttgagtcggtgcacctgggctcgccatgcctgctggaagcgctgtaccgc
accgagagcgcgtacccgcagcggctggagatcaaaccgtggaaggcctatcgcgactac
cgcaaagaaggctacgggctgctgatcctggaaggggaagactggcagcgggtccggagt
gcctttcaaaagaaactaatgaaaccaggggaagtgatgaagctggacaacaaaatcaat
gaggtcttggccgattttatgggcagaatagatgagctctgtgatgaaagaggccacgtt
gaagacttgtacagcgaactgaacaaatggtcgtttgaaagtatctgcctcgtgttgtat
gagaagagatttgggcttctccagaagaatgcaggggatgaagctgtgaacttcatcatg
gccatcaaaacaatgatgagcacgtttgggaggatgatggtcactccagtcgagctgcac
aagagcctcaacaccaaggtctggcaggaccacactctggcctgggacaccattttcaaa
tcagtcaaagcttgtatcgacaaccggttagagaagtattctcagcagcctagtgcagat
ttcctttgtgacatttatcaccagaatcggctttcaaagaaagaattgtatgctgctgtc
acagagctccagctggctgcggtggaaacgacagcaaacagtctaatgtggattctctac
aatttatcccgtaatccccaagtgcaacaaaagcttcttaaggaaattcaaagtgtatta
cctgagaatcaggtgccacgggcagaagatttgaggaatatgccgtatttaaaagcctgt
ctgaaagaatctatgaggcttacgccgagtgtaccatttacaactcggactcttgacaag
gcaacagttctgggtgaatatgctttacccaaaggaacagtgctcatgctaaatacccag
gtgttgggatccagtgaagacaattttgaagattcaagtcagtttagacctgaacgttgg
cttcaggagaaggaaaaaattaatccttttgcgcatcttccatttggcgttggaaaaaga
atgtgcattggtcgccgattagcagagcttcaactgcatttggctctttgttggattgtc
cgcaaatacgacatccaggccacagacaatgagcctgttgagatgctacactcaggcacc
ctggtgcccagccgggaactccccatcgcgttttgccagcgataa

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