Homo sapiens (human): 161742
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Entry
161742 CDS
T01001
Symbol
SPRED1, LGSS, NFLS, PPP1R147, hSpred1, spred-1
Name
(RefSeq) sprouty related EVH1 domain containing 1
KO
K04703
sprouty-related, EVH1 domain-containing protein
Organism
hsa
Homo sapiens (human)
Network
nt06526
MAPK signaling
Element
N01597
Regulation of GF-RTK-RAS-ERK signaling, SPRED and NF1
Disease
H01986
Legius syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
161742 (SPRED1)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
161742 (SPRED1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sprouty
WH1
SMC_ScpA
Motif
Other DBs
NCBI-GeneID:
161742
NCBI-ProteinID:
NP_689807
OMIM:
609291
HGNC:
20249
Ensembl:
ENSG00000166068
UniProt:
Q7Z699
Structure
PDB
PDBj
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All DBs
Position
15:38252836..38357249
Genome browser
AA seq
444 aa
AA seq
DB search
MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFI
RGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAI
EDISQGCPESKNEAEGADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRPSPFED
LNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIRHVSFQ
DEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDADSSIQFSKPDSKKSDYLYSCGDET
KLSSPKDSVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEENVRGKCQDAPDPIK
RCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCY
VPLRMCHRCGEACGCCGGKHKAAG
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaggagacggcgacttctgacaacgataatagttatgcacgagtgcgagctgtg
gtgatgacccgagatgactcaagtggtggatggttaccacttggagggagtggactaagc
agcgtcactgtcttcaaagtccctcatcaggaagagaatggctgtgctgacttttttatc
cgtggagagcgactcagggacaaaatggtggttttggaatgtatgcttaaaaaagacctc
atttataataaggtcactccaacatttcaccactggaagattgatgacaagaagtttggt
cttacgtttcaaagtcctgctgatgctagggcttttgatagaggtatccgaagagctata
gaggatatttctcaaggatgccccgaatcaaaaaatgaagctgaaggggcagatgactta
caagcaaatgaagaggattcttccagttctctagtgaaggatcacctttttcagcaagag
acagttgttaccagtgagccttatagaagctcaaatataagaccttctccctttgaagat
ctgaatgccagaagagtctacatgcaaagccaagccaatcagataacatttggtcagcca
ggcttggacattcagagcagaagtatggaatacgtacagcggcaaatatccaaggaatgt
ggaagcctaaagtcccaaaatagggtccctttgaaatcaatcagacatgtcagctttcaa
gatgaggatgagattgtcagaataaaccctcgagatatcttaatacgtcgctatgcagac
tacagacatcctgacatgtggaaaaatgacttggaaagagatgatgctgattccagtatt
cagttttctaaaccagacagtaaaaaatcagactatctgtactcttgtggggatgagact
aagttaagttcacccaaagactctgtggtatttaagacgcagccttcctcattaaaaatt
aagaagtcaaaacgaagaaaagaggatggtgaacgttctcgctgcgtatactgccaggaa
aggtttaatcatgaagaaaatgttaggggaaaatgtcaggatgctccagaccctattaaa
agatgcatatatcaagttagttgcatgctctgtgcagagagcatgttgtatcattgtatg
tcagactcagagggagatttttctgatccctgttcgtgtgacactagcgacgacaagttc
tgcttgcgatggttagccctggtagctttgtctttcattgtaccatgtatgtgctgctac
gtccctttgagaatgtgccatcgctgtggtgaggcatgtggttgctgtggtgggaaacat
aaagctgctggatga
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