Homo sapiens (human): 1639
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Entry
1639 CDS
T01001
Symbol
DCTN1, DAP-150, DP-150, HMND14, P135
Name
(RefSeq) dynactin subunit 1
KO
K04648
dynactin 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
hsa04962
Vasopressin-regulated water reabsorption
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05132
Salmonella infection
Network
nt06181
Salmonella
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
nt06515
Regulation of kinetochore-microtubule interactions
Element
N00976
Retrograde axonal transport
N00977
Mutation-caused aberrant Htt to retrograde axonal transport
N01158
Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01159
Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160
Mutation-caused aberrant SOD1 to retrograde axonal transport
N01295
Rab7-regulated microtubule minus-end directed transport
N01534
Dynein recruitment to the kinetochore
Disease
H00058
Amyotrophic lateral sclerosis (ALS)
H00856
Distal hereditary motor neuropathies
H00879
Perry syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
1639 (DCTN1)
09150 Organismal Systems
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
1639 (DCTN1)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
1639 (DCTN1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
1639 (DCTN1)
05016 Huntington disease
1639 (DCTN1)
05022 Pathways of neurodegeneration - multiple diseases
1639 (DCTN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
1639 (DCTN1)
03036 Chromosome and associated proteins [BR:
hsa03036
]
1639 (DCTN1)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
1639 (DCTN1)
Membrane trafficking [BR:
hsa04131
]
Endosome - Golgi transport
Rab GTPases and associated proteins
Rab associated proteins
1639 (DCTN1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Microtubules and associated factors
Dynactin complex
1639 (DCTN1)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Dynactins
1639 (DCTN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dynactin
CAP_GLY
TMF_DNA_bd
Motif
Other DBs
NCBI-GeneID:
1639
NCBI-ProteinID:
NP_004073
OMIM:
601143
HGNC:
2711
Ensembl:
ENSG00000204843
Pharos:
Q14203
(Tbio)
UniProt:
Q14203
Q6MZZ3
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(74361155..74391866)
Genome browser
AA seq
1278 aa
AA seq
DB search
MAQSKRHVYSRTPSGSRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGV
ILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKRE
GTDTTAKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSS
SEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAE
DKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT
ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQL
KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAE
STIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARE
TELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEA
SVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPG
GDHDCVLVLLLMPRLICKAELIRKQAQEKFELSENCSERPGLRGAAGEQLSFAAGLVYSL
SLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPL
TKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDI
ALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGPQVSDTLLDCRKHLTWVVAV
LQEVAAAAAQLIAPLAENEGLLVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTM
NKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLK
IKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQ
ADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGS
VPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLSHEGPG
SELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVE
KLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRH
RLVLTQEQLHQLHSRLIS
NT seq
3837 nt
NT seq
+upstream
nt +downstream
nt
atggcacagagcaagaggcacgtgtacagccggacgcccagcggcagcaggatgagtgcg
gaggcaagcgcccggcctctgcgggtgggctcccgtgtagaggtgattggaaaaggccac
cgaggcactgtggcctatgttggagccacactgtttgccactggcaaatgggtaggcgtg
attctggatgaagcaaagggcaaaaatgatggaactgttcaaggcaggaagtacttcact
tgtgatgaagggcatggcatctttgtgcgccagtcccagatccaggtatttgaagatgga
gcagatactacttccccagagacacctgattcttctgcttcaaaagtcctcaaaagagag
ggaactgatacaactgcaaagactagcaaactgcggggactgaagcctaagaaggcaccg
acagcccgaaagaccacaactcggcgacccaagcccacgcgcccagccagtactggggtg
gctggggccagtagctccctgggcccctctggctcagcgtcagcaggtgagctgagcagc
agtgagcccagcaccccggctcagactccgctggcagcacccatcatccccacgccggtc
ctcacctctcctggagcagtccccccgcttccttccccatccaaggaggaggagggacta
agggctcaggtgcgggacctggaggagaaactagagaccctgagactgaaacgggcagaa
gacaaagcaaagctaaaagagctggagaaacacaaaatccagctggagcaggtgcaggaa
tggaagagcaaaatgcaggagcagcaggccgacctgcagcggcgcctcaaggaggcgaga
aaggaagccaaggaggcgctggaggcaaaggaacgctatatggaggagatggctgatact
gctgatgccattgagatggccactttggacaaggagatggctgaagagcgggctgagtcc
ctgcagcaggaggtggaggcactgaaggagcgggtggacgagctcactactgacttagag
atcctcaaggctgagattgaagagaagggctcagatggcgctgcatccagttatcagctc
aagcagcttgaggagcagaatgcccgcctgaaggatgccctggtgaggatgcgggatctt
tcttcctcagagaagcaggagcatgtgaagctccagaagctcatggaaaagaagaaccaa
gagctggaagttgtgaggcaacagcgggagcgtctgcaggaggagctaagccaggcagag
agcaccattgatgagctcaaggagcaggtggatgctgctctgggtgctgaggagatggtg
gagatgctgacagatcggaacctgaatctggaagagaaagtgcgcgagttgagggagact
gtgggagacttggaagcgatgaatgagatgaacgatgagctgcaggagaatgcacgtgag
acagaactggagctgcgggagcagctggacatggcaggcgcgcgggttcgtgaggcccag
aagcgtgtggaggcagcccaggagacggttgcagactaccagcagaccatcaagaagtac
cgccagctgaccgcccatctacaggatgtgaatcgggaactgacaaaccagcaggaagca
tctgtggagaggcaacagcagccacctccagagacctttgacttcaaaatcaagtttgct
gagactaaggcccatgccaaggcaattgagatggaattgaggcagatggaggtggcccag
gccaatcgacacatgtccctgctgacagccttcatgcctgacagcttccttcggccaggt
ggggaccatgactgcgttctggtgctgttgctcatgcctcgtctcatttgcaaggcagag
ctgatccggaagcaggcccaggagaagtttgaactaagtgagaactgttcagagcggcct
gggctgcgaggagctgctggggagcaactcagctttgctgctggactggtgtactcgctg
agcctgctgcaggccacgctacaccgctatgagcatgccctctctcagtgcagtgtggat
gtgtataagaaagtgggcagcctgtaccctgagatgagtgcccatgagcgctccttggat
ttcctcattgaactgctgcacaaggatcagctggatgagactgtcaatgtggagcctctc
accaaggccatcaagtactatcagcatctgtacagcatccaccttgccgaacagcctgag
gactgtactatgcagctggctgaccacattaagttcacgcagagtgctctggactgcatg
agtgtggaggtaggacggctgcgtgccttcttgcagggtgggcaggaggctacagatatt
gccctcctgctccgggatctggaaacttcatgcagtgacatccgccagttctgcaagaag
atccgaaggcgaatgccagggacagatgctcctgggatcccagctgcactggcctttgga
ccacaggtatctgacacgctcctagactgcaggaaacacttgacgtgggtcgtggctgtg
ctgcaggaggtggcagctgctgctgcccagctcattgccccactggcagagaatgagggg
ctacttgtggctgctctggaggaactggctttcaaagcaagcgagcagatctatgggacc
ccctccagcagcccctatgagtgtctgcgccagtcatgcaacatcctcatcagtaccatg
aacaagctggccacagccatgcaggagggggagtatgatgcagagcggccccccagcaag
cctccaccggttgaactgcgggctgctgcccttcgtgcagagatcacagatgctgaaggc
ctgggtttgaagctcgaagatcgagagacagttattaaggagttgaagaagtcactcaag
attaagggagaggagctaagtgaggccaatgtgcggctgagcctcctggagaagaagttg
gacagtgctgccaaggatgcagatgagcgcatcgagaaagtccagactcggctggaggag
acccaggcactgctgcgaaagaaggagaaagagtttgaggagacaatggatgcactccag
gctgacatcgaccagctggaggcagagaaggcagaactaaagcagcgtctgaacagccag
tccaaacgcacgattgagggactccggggccctcctccttcaggcattgctactctggtc
tctggcattgctggtgaagaacagcagcgaggagccatccctgggcaggctccagggtct
gtgccaggcccagggctggtgaaggactcaccactgctgcttcagcagatctctgccatg
aggctgcacatctcccagctccagcatgagaacagcatcctcaagggagcccagatgaag
gcatccttggcatccctgccccctctgcatgttgcaaagctatcccatgagggccctggc
agtgagttaccagctggagcgctgtatcgtaagaccagccagctgctggagacattgaat
caattgagcacacacacgcacgtagtagacatcactcgcaccagccctgctgccaagagc
ccgtcggcccaacttatggagcaagtggctcagcttaagtccctgagtgacaccgtcgag
aagctcaaggatgaggtcctcaaggagacagtatctcagcgccctggagccacagtaccc
actgactttgccaccttcccttcatcagccttcctcagggccaaggaggagcagcaggat
gacacagtctacatgggcaaagtgaccttctcatgtgcggctggttttggacagcgacac
cggctggtgctgacccaggagcagctgcaccagcttcacagtcgcctcatctcctaa
DBGET
integrated database retrieval system
