Homo sapiens (human): 1657 Help Entry 1657              CDS       T01001                                  Symbol DMXL1 Name (RefSeq) Dmx like 1   KO K24155   rabconnectin-3a Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     1657 (DMXL1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     1657 (DMXL1) Membrane trafficking [BR:hsa04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     1657 (DMXL1)  Endosome - Lysosome transport   Acidification regulators    Rabconnectin-3 complex     1657 (DMXL1)    RAVE complex     1657 (DMXL1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Rav1p_C WD40 MIOS_WD40 Motif Other DBs NCBI-GeneID:  1657 NCBI-ProteinID:  NP_005500 OMIM:  605671 HGNC:  2937 Ensembl:  ENSG00000172869 UniProt:  Q9Y485 F1T0K4 LinkDB All DBs Position 5:119071027..119249127 Genome browser AA seq 3027 aa AA seqDB search MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKTDLNFGDWKCIWHCKTASQVHLMKFSPDG EFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSWR KTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRNA SSKERVQNALEVNLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHFHIA ASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQP SSEASVEDSNQADVKSDEETDDGVDDLKINPEKKELGCDKMVPNSSFTSLSSAAIDHQIE VLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDAN SLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISSGHNKSSNSLKLSIFTPNVMMI SKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNA LRTPDVDNPEQPFDALNIEECSLTQQNKSTVDVAFQDPSAVYSELILWRVDPVGPLSFSG GVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAK KLLSELSNPEISKYVGEVFNIVSQQSTARPGCIIALDPITKLHGRKTQLLHVFEEDFILN NLEKKSLGKDSILSNAGSSPNGFSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKV DTKLSEAVWQPEEHYSSSPEKILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEG VEIISIKPSAGHLSSSSIYPACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLA YIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPASNSRSSQDFVMHVSI FECESTGGSCWVLEQTIHLDELSTVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLV HLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQDQTGKETLAFPLWESTKVVPLSKFVLL RSVDLVSSVDGSPPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTP SITSLIKQSNSSSGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVDMEDSGLFEAAHVLSP TLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNHERRLRSLTISASG STTRDPQAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSNESTLSKSNQLSK ESYDELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPG LSRMEQMSLMALADTIATTSTDIGESRDRSQGGETLDECGLKFLLAVRLHTFLTTSLPAY RAQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRK CIEKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKA ALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAA YKSILRKKVLGIDSPVSELCSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDD QVLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFFT TASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKSS AVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDVP ISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSEDIIAVQLKFRACLKILTVE LRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQSAFGRNEDEFGLNEDA EDLPHQTKVKQLRENFQEKRQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQE SQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNLTHDILHAIINFDSPPH PDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMVYQTVLLPHRPSLKTGS LDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSS NELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVEEGEKQNKRFRPSKMSC RESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSSQSRAEYDSEESLGSDD DDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSS PLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAGPAILRHKALLEPTNTP FKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEADLGYPGGKARIIHKES DIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDDIEVETKGSEDFLVIHA RDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYL TGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKC CPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVH AFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTE EYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGAD GTMKMRILPDQFSPLNEVLKNDVKFML NT seq 9084 nt NT seq  +upstreamnt  +downstreamnt atgaacctgcaccaggtgctgaccggggctgtgaaccctggcgaccactgcttctccgtg ggcagcattggcgaccagcgcttcacggcttatgcatctggatgtgacattgtaatactg ggaagcgattttgaaagattacagataatcccaggagctaaacatggaaatattcaagtg ggatgtgtagactgttcaatgcaacaaggcaagattgcagcgtcttatggaaatgttatc tccatttttgaaccagttaacctaccaaaacaaaagaaaaatttggaattatatagtcag tggcagaaaagtggccaattttttctggaatcaatagcacacaatataacctgggatccc acaggcagtcgtcttttaactggttccagctatttgcaactctggtccaatactaacttg gagaagccaactgaagatgaaaatttaaataaaacagatcttaactttggagattggaaa tgcatttggcattgcaaaactgcttcccaagttcatttaatgaaattttcaccagatgga gaattttttgccactgctgggaaggatgactgtcttttgaaggtttggtataatgtagaa aactggcggacagctgttacttctccagatggaagttcagaaaaacaatcccaaggagaa attgacttttcttttgtgtatctggcccatcctcgagcagtaaatggattttcctggcgt aaaacaagcaaatatatgcctagggcttctgtatgtaatgtactgttgacttgctgcaaa gataatgtgtgtcgtctttgggtagagacatttttaccaaatgattgtttgctatacgga ggtgactgcagccattggactgaatcaattaatttaacaaataacttcaagagaaatgct tccagtaaagaacgagttcaaaatgctttagaagtaaatctgagacattttcgtagaggt cggaggagatcacttgctcttgtagcacatacgggatatctaccacatcagcaggatcct catcatgttcacaggaacactccactgcatgccaatgcactttgccactttcatattgca gccagcatcaacccagccacagacattccacttcttccatctattacatctctgagtcta aatgaaaatgaagagaagaccggaccttttgttgtacactggctaaacaataaagaactg cattttactttgtccatggaagtttttttacagcaacttagaaaaagttttgaacaacca tcttctgaggccagtgtagaagattctaatcaggcagatgtaaaatctgatgaagaaact gatgatggtgttgatgatctgaaaataaatcccgaaaagaaggaattaggctgtgataaa atggtaccaaactcaagttttacatcattatcgtcagctgccattgatcatcagattgaa gtacttctgtctgaatggagtaaaaatgcagatatgctatttagtattcatcccatggat ggttctttgctagtttggcatgtggattggctggatgaataccagcctggtatgtttcgt caagtacaggtgtcctttgtttccagaattccagtagctttccccacaggtgatgcaaac tctctctgtaaaagcataatgatgtatgcctgtaccaagaatgttgacttggctattcag caggggaaacaaaaaccttctggcctcacccgttccacatcaatgcttatttcttctggt cacaataaatcatctaatagtttaaaattaagtatttttacgcctaatgttatgatgata tcaaaacatgctgatggttctctgaatcagtggctggtcagttttgccgaggaatctgct ttttctactgttctcagtatttcccacaaatccagatattgtggtcatcgttttcatctt aatgatttagcttgccactcagtattaccattattgctgacaacatcacaccataatgca ttaaggacaccagatgttgataacccagagcaaccttttgatgctctaaatattgaagaa tgctctttgacacaacaaaataaaagcactgttgacgtggcatttcaggatcccagtgca gtttacagtgagcttattctgtggagggttgacccagttgggccattgtctttttctgga ggagtttctgagcttgcccggattaattctcttcatgtttctgccttttccaatgtggca tggctgcccactcttatacccagttattgtctgggtgcatactgcaactctcctagtgca tgctttgtagccagtgatggacaatatctgagattatatgaagcagttattgatgctaag aaacttttatctgagctttctaaccctgaaatttctaaatatgttggtgaagtctttaac atcgtcagtcaacaatcaacagccaggccaggatgcattattgcattagatcccattacc aaacttcatggcagaaaaacccaactgcttcatgtttttgaagaagacttcattttgaat aaccttgagaagaaaagccttggcaaagacagcattttatctaatgcaggcagctcacct aatggattttctgagaagttctacctaattgtaatagaatgcactcaagacaaccgttca ctgttacacatgtggaatttacatctaaagtcaattcctgtctcattagatgaaaaagta gatacaaaattatccgaagcggtttggcagccagaagaacattattcttcttctccagag aagatcctatctcctttttcacaaaagtatcaggcttgcagagcaaatctccagagtacc agcaggttgactctgttttcagaaatggtttatagccaagaattgcatttaccagaagga gttgagataataagtattaagccatcagcaggacatctgagttcatcttctatatatcct gcatgcagtgctccttatttattggcaacttcatgttcagatgagaaagtaagattctgg agatgcagagtaacagatggagaatctgccacgtcaaagaatggaaaaattgatcttgca tacatttgggaagaatggccattacttattgaagatggacttcagagcaatagtagtata actgtacctggtaggcctgtagaagttagctgtgcacatacaaatcgtttagcagtagct tataagcagcctgcatctaatagtagatcttcccaggactttgtgatgcatgtaagtatt tttgaatgtgagtcaacaggaggttcatgttgggtccttgagcagacaattcatttagat gagttaagcacagtattggattctggcattagtgttgatagcaatttagtggcctataat aaacaagacatgtatttatctagtaaagagaatatcacatcaaacacaaagcatttagtt cacttagattggatgtctagagaagacggttctcatatcctgactgtaggaattggatca aaactttttatgtatggacccctggctggcaaggtacaagaccaaactggtaaggaaacc ctggcatttcctctctgggagagtaccaaagttgtgcccctttctaaatttgtactatta cgaagtgtggacctagtttcttctgtagatggctccccaccttttcctgtttctttatcg tgggtccgggatggcatccttgtggtaggaatggactgtgaaatgcatgtgtattgccaa tggcaaccatcttctaaacaagaacctgttataacagattcgtacagtgggagcactcca tctataacaagtttaataaaacagagtaactccagttctgggttacatcctccaaagaaa actctgactcgatccatgaccagtcttgcacagaaaatctgtggaaagaaaactgcattc gatccttcagtggatatggaagattcaggtctttttgaagcagctcatgtactttccccg actctacctcagtatcatcccttgcagcttttggaactcatggatcttggtaaagttcgg agagccaaggccatcttgtcccatcttgttaagtgcattgctggggaagttgtggctctg aatgaagctgaatctaatcatgaacgccgccttaggtctctcacaatcagtgctagtgga agcactaccagagacccccaggcattcaacaaggctgaaaatacagattacacagaaata gattctgttcctccacttcctttatatgccttacttgcagcagatgatgatagctgttac tcatctttggagaaatctagtaatgagagtacgttaagtaaatcaaaccaattatctaaa gaaagttatgatgagctttttcagactcaacttctaatgactgatactcatatgttagag acagatgaagaaaatacaaagcctagagttattgacctttcacagtacagtccgacttac tttggacctgagcatgctcaggttctttctggccacttacttcattctagtttaccagga ctcagccggatggagcagatgtctttgatggccttagcagatacaattgcaactacaagc actgatattggagaaagccgagacagaagccaaggtggagaaactcttgatgaatgtggg ttaaaatttcttttggctgttcgactccatacctttcttacaacttcccttccagcctat cgagctcaactccttcaccaaggcctgtctacaagtcattttgcttgggcatttcactca gtagcagaagaagaactgctgaacatgttgccagccatgcagaaagatgatcccacttgg tctgaactaagagctatgggtgtggggtggtgggtccggaatacccgcatcttacgcaaa tgcatagaaaaagtagctaaagcagccttttatagaaagaatgatcctttagatgctgcc attttttaccttgcaatgaaaaagaaagctgtgatttggggattatatagagctgaaaaa aacaccaggatgacacagttttttggacacaattttgaggatgagaggtggcgtaaagca gctttaaagaatgctttttctttgctaggcaaacaaagatttgaacattctgcagcattt tttcttttagctggttgcctcagagatgcaattgaggtatgtcttgagaaattgaatgac attcagttggctcttgtaatagcaagactctatgagtctgaatttgatacatctgcagca tataaatctattttacgtaaaaaagttttgggaatcgattctcctgtcagtgaactgtgt tcattgaacataaatatgcatcatgatccttttcttcggagcatggcatattggattttg gaagattatagtggtgctctggaaacattaataaagcaacctatcagagagaatgatgat caagttttatcagccagtaatcctacagtttttaatttctacaattatctaagaacacat cctcttttgctgagacgtcattttggatcatctgatacattttccacacatatgagccta acaggaaaaagtggactggcaggaacaattaatttaagtgaaagacgtttattttttacc actgccagtgctcatttaaaagctggctgcccaatgttggctttggaagtattatcaaag atgcctaaagtcatcaagaaaacaagacctttttatagggcttctagttttctggatact agtaaagactgttctccttcttctccattaaagttggatgcaagggaagataagtcttct gctgttgattggtcacagtcactgataaatggttttggatcttcttcagagggttcctca gagaagcaatcaaactccactctttcttttgactggagccaaccaagtgttgtgtttcag gatgactctttagagttaaaatgggacagtgataatgatgaagaaaatgaggatgtccct atttcaatgaaagaactaaaacctttacagagaaaaacagataaaaagttggatgacata agttctaactacacagaatctttcagcacactagatgaaaatgaccttttaaatccatca gaagatataattgcagttcagttaaaatttagagcatgtttaaagattctcacagtagaa cttcgtactttatctactggctatgaaatagatggtggaaaattgcgttaccaactatac cactggcttgaaaaagaggtgatagctcttcagaggacttgtgacttttgctcagatgct gaagaactacagtctgcatttggcagaaatgaagatgaatttggattaaatgaggatgct gaagatttgcctcaccaaacaaaagtgaaacaactgagagaaaattttcaggaaaaaaga cagtggctcttgaagtatcagtcacttttgagaatgtttcttagttactgcatacttcat ggatcccatggtgggggtcttgcatctgtaagaatggaattgattttgcttttgcaagaa tctcagcaggaaacatcagaaccactattttctagccctctgtcagagcaaacctcagtg cctctcctctttgcttgtacagccaatgccaaaacagtagttgccaatccattattgcac cttagtaatctgacacatgatattctccatgccataataaactttgattcaccaccccac cctgatatccaaagcaataaagtgtatgtaatgcatactttagcagcttcactttctgct tgtatttatcagtgcctttgtggtagtcataactacagttcatttcagacgaatcagttt actggaatggtatatcagacagtactgcttcctcatcgaccttctttgaaaacaggaagc ttagatgaagcattaactcccaatacgtcaccagctcaatggccaggaataacttgtcta attcgacttttgaattcttctggcgaggaagcccagtcagggcttacagtcttgctctgt gagattctcacagcagtgtatcttagtctcttcatccatggcctggccacacattcaagt aatgagctatttcggattgtggcccatcctctaaatgagaaaatgtggtctgctgtgttt ggtggaggtgcacatgttcctagcaaagaacagacacattcaaaaactttacctgtttct tcactagttgaagaaggagaaaaacagaacaaacgttttaggccgtcaaaaatgtcttgc agagaatctgccccactgaccccttcctcggcaccagtaagccaggagtcactggcggtt aaagaaaagttcatcccacctgagctcagtatctgggactatttcatagctaagcctttt ctaccctcttctcaaagtagagccgaatatgattcagaggagagtctgggaagtgatgat gatgacaatgatgatgatgatgatgttttagcatcagatttccatctccaggaacattct aattcaaattcatatagttggtccttgatgcggttggcgatggtgcaattggtgctcaac aatttgaagactttttatcccttcgcaggtcatgatcttgcagagcttccagttagttca cctctttgtcatgcggttctaaaaactcttcaatgttgggaacaagttcttctccgacga cttgaaatccatggtgggccacctcaaaattatatcgcaagtcataccgccgaagagagt ttgtctgcaggtcctgcaattcttcgccacaaagctttactggaacctacaaacactcct ttcaaatccaaacaccatctggcactgtctgtgaagaggctttggcagtatttggtgaag caggaagaaattcaggaaacctttatcaaaaatatattcacaaagaaacggtgtctaaat gagatagaagcagatttgggatatcctggaggtaaagcaagaattattcataaggaatct gatatcattactgcgtttgctgttaataaggcaaatagaaactgcatagcaatcgcttcc agtcatgatgttcaagaactggatgtttctggaattctggccacacaggtctacacttgg gtagatgatgatatagaagtggaaaccaaaggatcagaagatttcttggttatacatgct cgtgatgatttaacagctgttcaaggtacaactccatatacacatagcaatcctggcact ccaatcaacatgccatggcttggtagtacacagactggcagaggagcatctgtgatgatt aagaaagccattaataatgttagaagaatgacttctcatccaactcttccttactatctg acaggagctcaagatggaagtgtcagaatgtttgaatggggccattctcaacaaataacc tgttttcgatctggtggcaattcaagagttacaagaatgagatttaactatcagggaaat aagtttggaatagttgatgctgatggatatttaagtttgtatcaaacaaactggaaatgt tgtccagttactggaagcatgcctaagccatacctgacttggcagtgtcataacaaaaca gccaatgattttgtcttcgttagttcctcctctctgatagctacagctggtctttcaact gacaatagaaacgtatgtttgtgggatactcttgtagcacctgccaatagtttagtccat gcatttacctgccatgacagtggagccacagttttagcatatgctccaaaacatcagcta ctaatatcaggtggcagaaaaggttttacatatgtatttgacctttgtcaacgacaacag aggcagcttttccagagccatgattctcctgttaaagccgttgctgttgatccaactgaa gagtactttgttacaggatctgccgaaggcaatataaagatttggagtctctctaccttt ggtcttctccatacttttgtcagtgaacatgctcggcagtccatttttagaaatattgga actggagtgatgcaaattgagacagggcctgcaaatcacattttctcctgtggagctgat ggaacaatgaaaatgagaatactgccagatcagtttagccctttaaatgaagtgttgaaa aatgatgtgaaatttatgctataa

Homo sapiens (human): 23312 Help Entry 23312             CDS       T01001                                  Symbol DMXL2, DEE81, DFNA71, EIEE81, PEPNS, RC3 Name (RefSeq) Dmx like 2   KO K24155   rabconnectin-3a Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome Disease H00604   Deafness, autosomal dominant H00606   Early infantile epileptic encephalopathy Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     23312 (DMXL2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     23312 (DMXL2) Membrane trafficking [BR:hsa04131]  Exocytosis   Small GTPases and associated proteins    Rab associated proteins     23312 (DMXL2)  Endosome - Lysosome transport   Acidification regulators    Rabconnectin-3 complex     23312 (DMXL2)    RAVE complex     23312 (DMXL2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Rav1p_C WD40 ANAPC4_WD40 NBCH_WD40 Motif Other DBs NCBI-GeneID:  23312 NCBI-ProteinID:  NP_056078 OMIM:  612186 HGNC:  2938 Ensembl:  ENSG00000104093 UniProt:  Q8TDJ6 LinkDB All DBs Position 15:complement(51447791..51622771) Genome browser AA seq 3036 aa AA seqDB search MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL NT seq 9111 nt NT seq  +upstreamnt  +downstreamnt atgcatctgcatcaggtcctcaccggagctgtcaaccctggagacaactgctactccgtg ggcagcgtcggggatgtccccttcacggcatatggatcaggctgtgatattgttattttg gcaaatgactttgaatgtgtacagatcattcctggtgctaagcatggaaacatccaagtc agctgtgtggagtgttctaaccaacaaggaagaattgcagcttcatatggtaatgctgtt tgtatatttgagcccttgggcataaattctcataaaagaaattgtcaactcaagtgccag tggcttaaaactgggcagttttttttgagttctgtgacatacaacttagcatgggatcct caagataatagattgttgacagcaactgattctattcagttgtgggctcctccaggagat gatattctggaagaggaggaagaaattgataatacagttcctcctgttttaaatgattgg aagtgtgtctggcagtgcaaaacctcagtatctgtacatttgatggaatggtctcctgat ggtgaatattttgctactgctggaaaggatgattgtcttttgaaagtgtggtatcctatg actggttggaagtcttcaattatacctcaggatcatcatgaagtaaaaaggagacagtcc tctactcaattttcttttgtttacttggcacatccccgagctgtgacaggtttttcgtgg cgcaaaactagcaagtatatgcccaggggttctgtctgtaatgtgttgttaacttcatgt catgatggtgtgtgccggctctgggcagaaactttattaccagaagactgtcttttgggt gagcagatttgtgagactaccacttccagcattgccagcagcctttctcatgctggaaga cacaaagacagaatacagcatgctcttgagacaatacaccatttgaaaaatttaaggaaa ggacagaggaggtcatctgttcttgtaactcatgctgaattaatgcccgaccagacagca atgcatgaagttcaaagacacatttcccaccatgcaaatgcactctgtcattttcatatt gcagcaagcatcaaccctgccacagatattccaaatgtcttggttggcactgcatttaat gttgatgatggaaatgggggctttgtagttcattggttaaacaacaaggaatttcatttt acatcatctacagaagtatttatgcatcaattacgaaaactttctgataagcaggtagat catgaaaatgatgatgcagatagagaagatgaggaacattcacaggaggatagagaacgg ggtttacatatgaaattagaccatgatttatccctggatagagaatctgaggcaggtaca ggatcatcagaacatgaagatggagaaagagaaggaagtcctagaacttactcacgactt agtgtaccaatgccactgcctacggttctgcttgatcggaagattgaaacgctgctaact gaatggaataagaatcctgatatgctttttacaatacaccctgtagatggtacctttcta gtgtggcatgtgaagtatttggatgaatataatcctggaatatttagacaagttcaggtt tctttttcttctcggattcctgttgcatttccctctggtgatgcaagctctcttagtaaa aatatcatgatgtatgcctgtataaatgcgacaaaagattctcaccacacgctgttacac caggaggggatgtctgtaggcagtcctcacggatcacagccacactctagatcccacagt acacatatgaacatcttagctcccacagtaatgatgatctctaaacacatagatggttct ttaaatcagtgggcagtcacttttgctgataagtctgcctttaccactgttctaactgta tctcacaaatttagatattgcggtcatcgatttcacctcaatgacctggcatgtcattca gttttaccactgttattgacatcctctcatcataatgctctattgactcctgaattagat tgtcagtgggactcagacaataaattaagtagattaatggaccctgtaaaacatataaaa ggttcctcgaaacaacctcttagaaatgcagcaactcgtacatttcatgacccaaatgca atctacagtgaacttattctgtggcgtgtagacccaataggacctttgtcatacactgga ggagtatcagaattggctcgaattaactctttacatacctcagcgttctctaatgtggct tggcttccaactctcattcccagttactgtctaggcacatactgcaattctgcaagtgct tgctttgttgcttctgatggcaaaaatctgagactctatcaagctgtagtggatgcaagg aaattattagatgaattgtcagacccagaatcttcaaaacttattggagaagtgtttaat attgtgagccaacagtctactgctcgacctggctgcattattgaactcgacgcaataacc aaccaatgtggctcaaatacacagttgcttcatgtgtttcaagaagacttcattatagga tataaaccacataaggaagatatggagaaaaaggaaacagaaatattttttcagccatca caaggataccgcccaccaccattttcagaaaagttctttctagtagtaattgagaaggac agcaataataactctattctgcatatgtggcaccttcatcttaaatctgtacaagcatgt ttagctaaagcttcagaaggggcttcctctgagagtctactttcagtccctggacagaag aacgtagattcttctccagaaacctctcctagtgtgagccccatgccacattcttcatca attgccaatcttcaaactgccagtaaacttattctgagttctagactggtgtatagccaa ccccttgatctcccagaatcagttgaagtaataagagcaacgccttcagcaggccatctg agttcttcttcaatttatccagtgtgccttgcaccttatttagtggttacaacttgttct gacaataaagtacgcttctggaaatgttgtatggaagccaacccagagtgtaataaaagt gatgagaaagaaatttatcattggaagagatggcctttgatgaatgatgaaggagaagat aatagcagtacagtgagcattgtgggaagaccagttgctgttagctgttcatacacaggt cgccttgcagtggcttataagcagcctatccaccataatggttttgtttctaaagaattt tccatgcatgtttgtatatttgaatgtgaatctacaggaggatcagagtgggttttagaa caaacaattcatcttgatgatttggttaaggttgggagtgtacttgattcaagggtcagc gtcgacagtaatctgtttgtgtatagcaagtcagatgcactcttgagcaaggatagatat cttattccgaatatcaaacatttagtacatttggactgggtatcaaaagaagatggctcc cacattcttacagtgggagtcggtgcgaatatcttcatgtatggaaggctttcaggaatt gtgactgagcaaaccaacagtaaggatggagtagctgtcatcactttaccactaggtggt agtatcaagcaaggagttaagtcaagatgggttcttcttagatctatagacttggtatct tctgttgatggtactccttcactgcctgtttctctctcttgggtaagagatgggatattg gtggtaggaatggattgtgaaatgcatgtatatgcacagtggaagcatgctgtcaaattt ggagacactgaagctgatagttctaatgcagaagaggcagcaatgcaagatcattcgacc tttaaatctaatatgctggcaagaaaaagtgttgttgaaggaacagctatttctgatgat gttttttgttcaccaactgtaattcaagatggtggcttatttgaggctgcacatgtactt tcccctactcttccacaatatcatccaactcagctgttagaattgatggatttagggaaa gtgcgaagggctaaagccattctctctcatttagtaaaatgtattgcaggtgaagtagca atagttagagatcctgatgctggagaaggaactaagcgacatctctctcgaactattagt gtaagtggcagtacagcaaaggaaacagtcaccgtaggaaaagatggtactcgagattat actgagatagattctatccctccactaccactatatgcattacttgctgcagatcaagat acatcctacagaatttcagaagaaagtacaaagataccacagagctatgaagatcagaca gtaagtcaaccagaggatcagtattcagagctgtttcaaatccaggatataccaacggat gatattgatttagagcctgaaaagagagaaaacaaatcaaaagtaataaatctttctcaa tatggaccagcttactttggccaagaacatgcaagggtactttcaagtcatcttatgcac tcaagtctaccaggccttacccgtttggagcagatgttccttgtagctttggctgataca gtggctactactagtactgagcttgatgaaagcagagataagagttgctcaggaagagat acattagatgagtgtggtttgagatacttgttagctatgcgcctacacacatgccttttg acatcgctgcctcctttataccgagtgcagctacttcatcaaggtgtctctacatgccat tttgcctgggcttttcattctgaggctgaagaagaactgattaatatgattccagcaatt cagagaggggacccccagtggtctgaattaagagctatgggcataggatggtgggtgagg aacattaacacgcttcgaagatgcattgaaaaggttgccaaagcttcttttcaaaggaac aatgatgccttagatgctgcactattctacctttcaatgaagaagaaagcagtagtgtgg ggtctgtttaggtcacagcatgatgaaaaaatgacaacatttttcagccacaactttaat gaagatagatggcgaaaagctgctttgaaaaatgctttttccttacttggaaaacaacgc tttgaacaatcggctgcttttttcttgctagctggttcattgaaagatgccatagaggta tgtcttgaaaaaatggaagatattcagctagccatggttattgcccgtttatatgaatct gaatttgagacttcatccacttatatatccatcctaaatcagaagattttgggttgccaa aaggatggctcaggattcagttgcaaaagattacatcctgatcctttcctgcgtagtctt gcctattgggtaatgaaagattacacccgagccttggacacattactggaacaaacacca aaggaggatgatgaacatcaagttatcatcaagtcttgtaacccggtggcatttagtttt tataactaccttcgaactcatcctttgctcattcgaagaaatcttgcctcccctgaagga actttggcaaccttaggtctcaaaactgagaagaactttgttgataaaattaacctcata gaaagaaaattattctttaccactgcaaatgctcattttaaagttggatgccctgtttta gccttggaggtactctccaaaattccaaaagtaaccaaaacatctgccttatctgcaaaa aaagatcagcctgacttcatttctcacaggatggatgatgtaccttcacattcaaaagct ctgagtgatggcaatggaagttctggcattgaatggtcaaatgtaacttcatcacagtat gactggagtcagccaatagtaaaagttgatgaggaacctcttaatcttgattggggtgaa gatcacgacagtgccttagatgaagaggaagacgatgctgttggtttagtgatgaaaagt acagatgccagggaaaaagataaacaatcagatcagaaggcctcagaccctaacatgtta ttaacacctcaggaagaggatgatcctgaaggtgatactgaagttgatgtgattgctgaa caactaaaattcagagcttgtttaaagatccttatgactgaattaagaacattggctaca ggttatgaagtagatggaggaaaactcagatttcaactctataactggcttgaaaaggaa attgctgccttgcatgagatatgtaatcatgaatcagttattaaagagtattccagtaag acatattccaaagtagagagtgatctgctggatcaggaagaaatggtagacaaaccagat attggttcctatgagcgccatcaaatagaaagaagaagattgcaggccaaacgagagcat gcagaaagacgaaagtcgtggttgcagaaaaaccaagatctcctgagagtatttctcagc tactgtagccttcatggggcccaaggtggtggtttggcttcagtaaggatggaactcaaa tttttgctacaagaatcacaacaggaaactacagtaaagcagctccagtctccactacca ctgcctaccaccctacctctgctttcagcaagtattgcgtcaacaaaaacagtcatagct aatcctgtattgtacttaaataatcacatccatgatatactttatactattgttcagatg aaaacaccacctcatcccagtattgaagatgtgaaggtgcacacacttcattcactagca gcatcactttctgcatcaatttaccaagcattatgtgacagtcatagctacagtcaaaca gaaggaaatcagtttacaggaatggcttatcaaggacttcttttaagtgatcgtagaaga ctaaggacagaaagcattgaagaacacgcaacaccaaattcatctcctgctcaatggcct ggtgtgagctcacttattaatcttttgagttcagcccaagatgaagaccagccaaaactg aacattttgctatgtgaagctgttgttgctgtttacttaagtttattgatacatgctctt gccacaaattcctccagtgaattatttcggcttgcagcccacccattaaataatcgaatg tgggctgctgtttttggaggcggtgtaaaacttgttgtgaaacctcgaagacaatcagaa aatatttcagcacctcctgtcctttctgaagacatagataaacaccgtaggagatttaac atgagaatgctcgtccctggaaggcctgtaaaagatgctaccccaccaccggtgcctgca gaaagaccatcttacaaagaaaaatttattcctcccgaacttagtatgtgggattatttt gttgcaaagccatttcttcctttgtctgatagtggtgttatatatgattctgatgaaagc attcatagtgatgaagaagatgatgcctttttttcagatacacaaatacaggagcaccaa gatccaaattcctatagctgggctcttctacatttgacaatggttaaactagcacttcac aatgtcaagaatttctttcctattgctggactggaattctctgagctgcctgtaacatca ccattaggtattgctgtgattaaaaacttggagaactgggaacagatcttgcaagagaaa atggatcagtttgaaggtccaccccctaactatatcaacacatatccaactgacctttca gtgggagctggaccagctattcttcgaaataaagcaatgctagaacctgaaaatacccca ttcaagtcccgggattcttctgcatttccagtcaaacgactttggcatttccttgttaaa caagaggtccttcaagagacatttattagatatattttcactaagaaaagaaagcagagt gaggttgaagctgatctgggctatccaggtggaaaggcgaaagtcatccataaggaatct gatatgatcatggcattttctgttaataaggcaaattgtaatgaaattgttttggcttca acacatgatgttcaagaacttgatgttacttctctactggcctgtcagtcatacatatgg atcggagaagaatatgacagagaatccaaaagttcagatgatgttgattatcgtggttcc actacaactctttatcaacccagtgcaacatcctattcagcaagtcaggtgcatccacct tcatctctgccatggctgggcactggacagactagcactggagctagtgtgcttatgaaa aggaatctacataatgttaagagaatgacttcacacccagtccatcaatactatcttaca ggtgctcaggacggcagtgtacgaatgtttgaatggacgcggcctcagcaacttgtctgc tttcgtcaagctggcaatgcaagagttactagattatattttaattcacaaggcaacaag tgtggtgttgcggatggagagggttttctgagtatctggcaagttaaccaaactgcatca aatcctaaaccttatatgagttggcagtgccacagtaaagccacaagtgactttgcattt attacctcttcaagtctagttgccacatctggacactccaatgacaatagaaatgtttgc ctctgggacacattaatatcacccggaaacagcctcattcatggtttcacgtgccacgat catggtgccacggtactgcagtatgcacccaaacagcaactcctaatctcggggggtagg aaaggacacgtctgcatttttgacatcaggcaaaggcagctcattcacacgttccaggcc catgactcagctattaaggctctggccttggatccctatgaggaatattttaccacaggt tcagcagaaggtaacataaaggtttggagattgacaggccatggcctaattcattcattt aaaagtgaacatgctaagcagtccatatttcgaaacattggggctggagtcatgcagatt gacatcatccagggcaatcggctcttctcctgtggtgcagatggcacgctgaaaaccagg gttttgcccaatgcttttaacatccctaacagaattcttgacattctataa

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