Homo sapiens (human): 1687
Help
Entry
1687 CDS
T01001
Symbol
GSDME, DFNA5, ICERE-1
Name
(RefSeq) gasdermin E
KO
K22146
gasdermin-E
Organism
hsa
Homo sapiens (human)
Pathway
hsa04623
Cytosolic DNA-sensing pathway
Disease
H00604
Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
1687 (GSDME)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
1687 (GSDME)
Transporters [BR:
hsa02000
]
Other transporters
Pores ion channels [TC:
1
]
1687 (GSDME)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Gasdermin
Gasdermin_C
Ig-like_KY
Motif
Other DBs
NCBI-GeneID:
1687
NCBI-ProteinID:
NP_001120925
OMIM:
608798
HGNC:
2810
Ensembl:
ENSG00000105928
UniProt:
O60443
LinkDB
All DBs
Position
7:complement(24698355..24795539)
Genome browser
AA seq
496 aa
AA seq
DB search
MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGD
VLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRK
QEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKC
GGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGK
QGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFA
ELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFL
QLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLL
RALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLL
LCITLNGLCALGREHS
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgtttgccaaagcaaccaggaattttcttagagaagttgatgctgatggtgacctgatt
gcagtatcaaatctgaatgactctgataagttacagcttctaagtctggtgacaaaaaag
aagagattctggtgctggcagagacccaagtaccagtttttatccctcacccttggcgat
gtactcatagaagaccaatttccgagtccagtggtcgtggagtcggactttgtgaaatac
gagggcaagtttgcaaaccacgtgagtggaaccctggagactgcactggggaaggtcaag
ctgaacctggggggcagcagccgcgtagagagccagtcttcatttggaaccctgaggaag
caggaggtggatttgcagcagctcatcagagactctgccgagagaacaataaatctgaga
aaccctgtgctccagcaggtgctggaaggaaggaatgaggtcctgtgcgttttgacacag
aagatcacgacgatgcagaagtgtgtgatctctgagcacatgcaggtcgaggagaagtgt
ggtggcatcgtgggcatccagaccaagacggtgcaggtgtcagcgacggaggatgggaat
gtcaccaaggactccaacgtggtgctggagatcccagctgccaccaccattgcctacggt
gtcattgagttatacgtgaaactggacggccagttcgagttctgccttctccgagggaag
caaggtggcttcgagaacaagaagagaattgactctgtctacctggaccccctggtcttt
cgagagtttgcattcatagacatgccagatgctgcgcatgggatatcttcccaggatgga
ccattaagtgttttaaagcaagcgaccctgctcctggagaggaatttccatccatttgcg
gagctgcctgagccacaacagacagctttgagtgacatcttccaggcggtcctatttgat
gatgaactactcatggtcctggaaccagtgtgcgatgacctggtcagcggcctctcgccc
acagtggcggtgctgggggagctgaagccccggcagcagcaggaccttgtggccttcctg
cagctggtggggtgcagcttacagggtgggtgtccgggccccgaggatgcaggcagcaag
cagctgtttatgacagcctacttcttggtcagtgccctcgcagaaatgccagatagcgca
gcagctctgctgggcacttgctgcaaactccagatcattcccacactgtgccacttgctt
cgtgctctgtctgatgatggagtatctgatcttgaagacccaaccttgactcccctgaaa
gatacagaaaggtttgggattgtgcagcgcttgtttgcctcagctgacattagtctggag
agactgaagtcatctgtgaaagctgtcattctgaaggactctaaagtcttcccactgctt
ctttgtataaccctgaatggactctgtgctttaggcagagaacattcatga
DBGET
integrated database retrieval system
