Homo sapiens (human): 176
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Entry
176 CDS
T01001
Symbol
ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, SSOAOD
Name
(RefSeq) aggrecan
KO
K06792
aggrecan 1
Organism
hsa
Homo sapiens (human)
Disease
H00448
Familial osteochondritis dissecans
H00765
Spondyloepiphyseal dysplasia, Kimberley type
H02187
Spondyloepimetaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00535 Proteoglycans [BR:
hsa00535
]
176 (ACAN)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
176 (ACAN)
04091 Lectins [BR:
hsa04091
]
176 (ACAN)
Proteoglycans [BR:
hsa00535
]
Extracellular matrix (ECM) proteoglycans
Aggrecan / versican family
176 (ACAN)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Hyaluronan
Extracellular matrix or blood plasma proteins
176 (ACAN)
Lectins [BR:
hsa04091
]
C-Type lectins
Lecticans
176 (ACAN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Xlink
Lectin_C
V-set
Sushi
EGF
EGF_2
I-set
Ig_3
ig
Antimicrobial25
EGF_3
Motif
Other DBs
NCBI-GeneID:
176
NCBI-ProteinID:
NP_037359
OMIM:
155760
HGNC:
319
Ensembl:
ENSG00000157766
UniProt:
P16112
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:88803436..88875353
Genome browser
AA seq
2530 aa
AA seq
DB search
MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV
TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV
QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA
IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE
TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG
WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN
FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF
APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF
HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS
PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES
HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT
GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA
VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV
PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE
PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD
SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG
EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL
ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG
VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED
ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS
GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV
LETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLET
TAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSA
SGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSAS
EVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAP
ETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEG
RGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPS
GFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPS
GLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPS
GEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSG
AYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSG
FLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSE
FVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESS
SETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGE
ASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPES
EWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPA
RSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRET
WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFEN
WRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFG
QKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRH
PRRSRPSTAH
NT seq
7593 nt
NT seq
+upstream
nt +downstream
nt
atgaccactttactctgggttttcgtgactctgagggtcatcactgcagctgtcactgta
gaaacttcagaccatgacaactcgctgagtgtcagcatcccccaaccgtccccgctgagg
gtcctcctggggacctccctcaccatcccctgctatttcatcgaccccatgcaccctgtg
accaccgccccttctaccgccccactggccccaagaatcaagtggagccgtgtgtccaag
gagaaggaggtagtgctgctggtggccactgaagggcgcgtgcgggtcaacagtgcctat
caggacaaggtctcactgcccaactacccggccatccccagtgacgccaccttggaagtc
cagagcctgcgctccaatgactctggggtctaccgctgcgaggtgatgcatggcatcgag
gacagcgaggccaccctggaagtcgtggtgaaaggcatcgtgttccattacagagccatc
tctacacgctacaccctcgactttgacagggcgcagcgggcctgcctgcagaacagtgcc
atcattgccacgcctgagcagctgcaggccgcctacgaagacggcttccaccagtgtgac
gccggctggctggctgaccagactgtcagataccccatccacactccccgggaaggctgc
tatggagacaaggatgagtttcctggtgtgaggacgtatggcatccgagacaccaacgag
acctatgatgtgtactgcttcgccgaggagatggagggtgaggtcttttatgcaacatct
ccagagaagttcaccttccaggaagcagccaatgagtgccggcggctgggtgcccggctg
gccaccacgggccagctctacctggcctggcaggctggcatggacatgtgcagcgccggc
tggctggccgaccgcagcgtgcgctaccccatctccaaggcccggcccaactgcggtggc
aacctcctgggcgtgaggaccgtctacgtgcatgccaaccagacgggctaccccgacccc
tcatcccgctacgacgccatctgctacacaggtgaagactttgtggacatcccagaaaac
ttctttggagtggggggtgaggaggacatcaccgtccagacagtgacctggcctgacatg
gagctgccactgcctcgaaacatcactgagggtgaagcccgaggcagcgtgatccttacc
gtaaagcccatcttcgaggtctcccccagtcccctggaacccgaggagcccttcacgttt
gcccctgaaataggggccactgccttcgctgaggttgagaatgagactggagaggccacc
aggccctggggctttcccacacctggcctgggccctgccacggcattcaccagtgaggac
ctcgtcgtgcaggtgaccgctgtccctgggcagccgcatttgccagggggggtcgtcttc
cactaccgcccgggacccacccgctactcgctgacctttgaggaggcacagcaggcctgc
ctgcgcacgggggcggtcattgcctcgccggagcagctccaggccgcctacgaagcaggc
tatgagcagtgtgacgccggctggctgcgggaccagaccgtcagataccccattgtgagc
ccccggaccccatgcgtgggtgacaaggacagcagcccaggggtcaggacctatggcgtg
cgcccatcaacagagacctacgatgtctactgctttgtagacagacttgagggggaggtg
ttcttcgccacacgccttgagcagttcaccttccaggaagcactggagttctgtgaatct
cacaatgctacgctggccaccacgggccagctctacgccgcctggagccgcggcctggac
aagtgctatgccggctggctggccgacggcagcctccgctaccccatcgtcaccccaagg
cctgcctgcggtggggacaagccaggcgtgagaacggtctacctctaccctaaccagacg
ggcctcccagacccactgtcccggcaccatgccttctgcttccgaggcatttcagcggtt
ccttctccaggagaagaagagggtggcacacccacatcaccctctggtgtggaggagtgg
atcgtgacccaagtggttcctggtgtggctgctgtccccgtagaagaggagacaactgct
gtaccctcaggggagactactgccatcctagagttcaccaccgagccagaaaaccagaca
gaatgggaaccagcctataccccagtgggcacatccccgctgccagggatccttcctact
tggcctcccactggcgcagcaacagaggaaagtacagaaggcccttctgcaactgaagtg
ccctctgcctcagaggaaccatccccctcagaggtgccattcccctcagaggagccatcc
ccctcagaggaaccattcccctcagtgaggccattcccctcagtggagctgttcccctca
gaggagccattcccctccaaggagccatccccctcagaggaaccatcagcctcggaagag
ccgtatacaccttcaccccccgtgcccagctggactgagctgcccagctctggggaggaa
tctggggcccctgatgtcagtggtgacttcacaggcagtggagatgtttcaggacacctt
gacttcagtgggcagctgtcaggggacagggcaagtggactgccctctggagacctggac
tccagtggtcttacttccacagtgggctcaggcctgcctgtggaaagtggactaccctca
ggggatgaagagagaattgagtggcccagcactcctacggttggtgaactgccctctgga
gctgagatcctagagggctctgcctctggagttggggatctcagtggacttccttctgga
gaagttctagagacctctgcctctggagtaggagacctcagtgggcttccttctggagaa
gttctagagaccactgcccctggagtagaggacatcagcgggcttccttctggagaagtt
ctagagaccactgcccctggagtagaggacatcagcgggcttccttctggagaagttcta
gagaccactgcccctggagtagaggacatcagcgggcttccttctggagaagttctagag
accactgcccctggagtagaggacatcagcgggcttccttctggagaagttctagagacc
actgcccctggagtagaggacatcagcgggcttccttctggagaagttctagagaccact
gcccctggagtagaggacatcagcgggcttccttctggagaagttctagagaccgctgcc
cctggagtagaggacatcagcgggcttccttctggagaagttctagagaccgctgcccct
ggagtagaggacatcagcgggcttccttctggagaagttctagagaccgctgcccctgga
gtagaggacatcagcgggcttccttctggagaagttctagagaccgctgcccctggagta
gaggacatcagcgggcttccttctggagaagttctagagaccgctgcccctggagtagag
gacatcagcgggcttccttctggagaagttctagagaccgctgcccctggagtagaggac
atcagcgggcttccttctggagaagttctagagaccgctgcccctggagtagaggacatc
agcgggcttccttctggagaagttctagagactgctgcccctggagtagaggacatcagc
gggcttccttctggagaagttctagagactgctgcccctggagtagaggacatcagcggg
cttccttctggagaagttctagagactgctgcccctggagtagaggacatcagcgggctt
ccttctggagaagttctagagactgctgcccctggagtagaggacatcagcgggcttcct
tctggagaagttctagagactgctgcccctggagtagaggacatcagcgggcttccttct
ggagaagttctagagactgctgcccctggagtagaggacatcagcgggcttccttctgga
gaagttctagagactgctgcccctggagtagaggacatcagcgggcttccttctggagaa
gttctagagactgctgcccctggagtagaggacatcagcgggcttccttctggagaagtt
ctagagactgctgcccctggagtagaggacatcagcgggcttccttctggagaagttcta
gagactactgcccctggagtagaggagatcagcgggcttccttctggagaagttctagag
actactgcccctggagtagatgagatcagtgggcttccttctggagaagttctagagact
actgcccctggagtagaggagatcagcgggcttccttctggagaagttctagagacttct
acctctgcggtaggggacctcagtggacttccttctggaggagaagttctagagatttct
gtctctggagtagaggacatcagtgggcttccttctggagaggttgtagagacttctgcc
tctggaatagaggatgtcagtgaacttccttcaggagaaggtctagagacctctgcttct
ggagtagaggacctcagcaggctcccttctggagaagaagttctagagatttctgcctct
ggatttggggacctcagtggacttccttctggaggagaaggtctagagacctctgcttct
gaagtagggactgacctcagtgggcttccttctggaagggagggtctagagacttcagct
tctggagctgaggacctcagtgggttgccttctggaaaagaagacttggtggggtcagct
tctggagacttggacttgggcaaactgccttctggaactctaggaagtgggcaagctcca
gaaacaagtggtcttccctctggatttagtggtgagtattctggggtggaccttggaagt
ggcccaccctctggcctgcctgactttagtggacttccatctggattcccaactgtttcc
ctagtggattctacattggtggaagtggtcacagcctccactgcaagtgaactggaaggg
aggggaaccattggcatcagtggtgcaggagaaatatctggactgccctccagtgagctg
gacattagtgggagagctagtggactcccttcaggaactgaactcagtggccaagcatct
gggtctcctgatgtcagtggggaaatacctggactctttggtgtcagtggacagccatca
gggtttcctgacactagtggggaaacatctggagtgactgagcttagcgggctgtcctct
ggacaaccaggtattagtggagaagcatctggagttctttatggcactagtcaacccttt
ggcataactgatctgagtggagaaacatctggggtccctgatctcagtgggcagccttca
gggttaccagggttcagtggggcaacatcaggagtccctgacctggtttctggtaccacg
agtggcagcggtgaatcttctgggattacatttgtggacaccagtttggttgaagtggcc
cctactacatttaaagaagaagaaggcttagggtctgtggaactcagtggcctcccttcc
ggagaggcagatctgtcaggcaaatctgggatggtggatgtcagtggacagttttctgga
acagtcgattccagtgggtttacatcccagactccggaattcagtggcctaccaagtggc
atagctgaggtcagtggagaatcctccagagctgagattgggagcagcctgccctcggga
gcatattatggcagtggaactccatctagtttccccactgtctctcttgtagacagaact
ttggtggaatctgtaacccaggctccaacagcccaagaggcaggagaagggccttctggc
attttagaactcagtggtgctcattctggagcaccagacatgtctggggagcattctgga
tttctggacctaagtgggctgcagtccgggctgatagagcccagcggagagccaccaggt
actccatattttagtggggattttgccagcaccaccaatgtaagtggagaatcctctgta
gccatgggcaccagtggagaggcctcaggacttccagaagttactttaatcacttctgag
ttcgtggagggtgttactgaaccaactatttctcaggaactaggccaaaggccccctgtg
acacacacaccccagctttttgagtccagtggaaaagtctccacagctggggacattagt
ggagctaccccagtgctccctgggtctggagtagaagtatcatcagtcccagaatctagc
agtgagacgtccgcctatcctgaagctgggttcggggcatctgccgcccctgaggccagc
agagaagattctgggtcccctgatctgagtgaaaccacctctgcattccacgaagctaac
cttgagagatcctctggcctaggagtgagcggcagcactttgacatttcaagaaggcgag
gcgtccgctgccccagaagtgagtggagaatccaccaccaccagtgatgtggggacagag
gcaccaggcttgccttcagccactcccacggcttctggagacaggactgaaatcagcgga
gacctgtctggtcacacctcgcagctgggcgttgtcatcagcaccagcatcccagagtct
gagtggacccagcagacccagcgccctgcagagacgcatctagaaattgagtcctcaagc
ctcctgtactcaggagaagagactcacacagtcgaaacagccacctccccaacagatgct
tccatcccagcttctccggaatggaaacgtgaatcagaatcaactgctgcagcccccgcc
aggtcctgtgcagaggagccctgtggagctgggacctgcaaggagacagagggacacgtc
atatgcctgtgcccccctggctacactggcgagcactgtaacatagaccaggaggtatgt
gaggagggctggaacaagtaccagggccactgttaccgccacttcccggaccgcgagacc
tgggtggatgctgagcgccggtgtcgggagcagcagtcacacctgagcagcatcgtcacc
cccgaggagcaggagtttgtcaacaacaatgcccaagactaccagtggatcggcctgaac
gacaggaccatcgaaggggacttccgctggtcagatggacaccccatgcaatttgagaac
tggcgccccaaccagcctgacaacttttttgccgctggagaggactgtgtggtgatgatc
tggcacgagaagggcgagtggaatgatgttccctgcaattaccacctccccttcacgtgt
aaaaagggcacagtggcctgcggagagccccctgtggtggagcatgccaggaccttcggg
cagaagaaggaccggtatgagatcaattccctggtgcggtaccagtgcacagaggggttt
gtccagcgccacatgcccaccatccggtgccagcccagcgggcactgggaggagcctcag
atcacctgcacagaccccaccacctacaaacgcagactacagaagcggagctcacggcac
cctcggaggagccgccccagcacagcccactga
DBGET
integrated database retrieval system
