KEGG   Homo sapiens (human): 1768
Entry
1768              CDS       T01001                                 
Symbol
DNAH6, DNHL1, Dnahc6, HL-2, HL2
Name
(RefSeq) dynein axonemal heavy chain 6
  KO
K10408  dynein axonemal heavy chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160  Mutation-caused aberrant SOD1 to retrograde axonal transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    1768 (DNAH6)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    1768 (DNAH6)
   05016 Huntington disease
    1768 (DNAH6)
   05022 Pathways of neurodegeneration - multiple diseases
    1768 (DNAH6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    1768 (DNAH6)
   04812 Cytoskeleton proteins [BR:hsa04812]
    1768 (DNAH6)
Cilium and associated proteins [BR:hsa03037]
 Motile cilia and associated proteins
  Dynein arm
   1768 (DNAH6)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1768 (DNAH6)
SSDB
Motif
Pfam: AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_5 DYN_lid AAA_lid_1 AAA AAA_22 AAA_18 TsaE nSTAND3 AAA_16 Sigma54_activat NB-ARC Caudo_TAP
Other DBs
NCBI-GeneID: 1768
NCBI-ProteinID: NP_001361
OMIM: 603336
HGNC: 2951
Ensembl: ENSG00000115423
Pharos: Q9C0G6(Tbio)
UniProt: Q9C0G6
Structure
LinkDB
Position
2:84459572..84819589
AA seq 4158 aa
MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTENESDTQILTFRHITKAQ
EKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAGIIKRPVSIAKKSFATSST
QFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLFGTRSSAYPKYTFHDREEVVK
ANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRA
VTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKS
LQKNLFIVNPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERL
GEFRNEAKYVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPTYGDSE
KMTYTEQASKRHYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTPSADVI
QKWITEEKPEVPDKKGTLMVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDGILGA
VNHCQNTVLSVPNLVPDSYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQI
KETIQAAFESARIYAATFEKFQIFFKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDA
VALRPTRNVGLLLIDTRLLREKLIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKL
EFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMK
PSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDK
IRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWD
KLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVI
IDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAA
LEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPL
KTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKE
IMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDEL
LEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSP
EGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV
ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNILTA
LITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGYEYLG
ACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSD
GLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGR
EIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKI
LARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRALQDSN
LPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKVIQFY
ETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSITMGE
LYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLC
LANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKGISKKL
TEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLESLILGKDGVNLAM
EQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFDDNPDARLPNSGDLWSIHM
DFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFTGITGV
GKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKRIV
IFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDVTIISACAPPGGGRN
PVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEASVEIYNKM
SVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRVFHDRLINN
EDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTAN
VLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLA
AHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINN
ILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSP
VGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVN
VHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLL
ETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAE
ETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLN
AKPDWPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKS
MCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEY
DKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAA
ACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL
ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGL
PVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLP
EVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKIL
RMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSV
MYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSR
GLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFA
CCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAH
QDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNT
PLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQN
CHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGL
RANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSD
RECALLNLKLYCKEGKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEED
YKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILE
VQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQ
EVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPL
GSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKY
SVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDA
LPGQMNPVLPVVHFEPQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKR
SKDYWIAKGSALLCQLSE
NT seq 12477 nt   +upstreamnt  +downstreamnt
atgacttttcgggccacagatagtgaatttgacctgacaaatattgaagagtatgccgaa
aattctgcactttcaagactgaataatataaaagccaaacaaagagtgagttatgtgaca
tccacagaaaatgaatctgatacacaaatcctaacgtttaggcacattacaaaagctcag
gagaagacaagaaaacgacagcagcctataaaactagagcctttgccagtgctaaaagtc
taccaagatcataagcagccagaatacatacatgaacagaaccgatttcagttaatgact
gcaggaatcattaaacgtccagtaagcatagcaaaaaaaagttttgccacatcatctact
cagtttcttgagcatcaagatgctgtgaaaaaaatgcagattcatcggccctatgttgag
gtgttctctccctctcctcctaaactgccacatactggtattggaaaaagaggtctcttt
gggactagatcttcagcttaccctaagtacacttttcacgaccgagaagaagttgttaaa
gccaacattcgtgatcccttgcaaatcattaaaataatacgtgaaaatgaacatcttgga
tttctttatatgatccctgcagtgccaagatcatccattgaatatgatacatataatcta
aaagttgtaagttatgagaacatcaataaaaatgactactatactattagccaaagggca
gtaacacacatttataatgaagacattgaatttatcgaaattgatcgatgggaacaggaa
tatctgtatcacagagaactcactaagattcccatattttcactgttccggaaatggaag
gcttttagtgtatggaggaagaatgtccgctccaagaaaatcactggatgtcaaaaatct
ctacaaaaaaatttgttcattgttaatcctcatttgcgaccagctcttcttaaaataaat
gaattgtgttatcatttgagttttatgggactttgttatattgaaaagtgtcacacctac
accctgcaggaatttaaggccgcacaagtcatacggctagcagaggtgacagaacgccta
ggagaatttcgaaatgaggcaaaatatgtagtcaggagggcttgtcgatttgctttgcgt
gctgcaggatttgttcctgatgactgtgcatttggaccttttgaggattatcataaagtg
cagagcagtggaagtttcattaatacaccacatgagttgcccacttatggagactctgag
aaaatgacatatacagaacaggccagcaaaaggcattattgcatgaggctgacgtgcttt
attcgtctaaacgactatctaattgagaacacaatgcacatcttaacggtaaatgctgtt
aattcgcttttgaaccatctcactgacaagctaaaacgaacaccttcagcagatgtcatt
cagaaatggattactgaagagaagcctgaagtccctgataaaaaggggacccttatggtg
gaaaagcaagaagaagatgaatctctcatccccatgtttctcacagaactaatgttgaca
gtccagtcactgctctttgagccttctctggaagactttctggatggtattttgggtgca
gttaatcactgtcaaaacactgtgttatcagttcctaatctcgtgcctgattcgtatttt
gatgctttcaccagcccttatattaacaacaaacttgaaggaaaaacctgtggaactggg
ccaagtttagcagcagtatttgaggatgataagaattttcacacaattatttctcaaata
aaggaaaccattcaggccgcatttgaatcagcccgcatctatgcagctacctttgaaaag
ttccagatattcttcaaggaaaatgaaagtcttgatttacaagctcttaaacttcaggaa
cctgatattaacttttttagtgaacaactggaaaaatatcacaaacagcacaaggacgca
gtagcgctcagacccaccagaaatgtaggattgctgctcattgatactaggcttctaaga
gaaaaattaattccatcacctttgcgatgcttagaggtgctaaattttatgcttcctcgt
caaagcaagaaaaaagtggatgccattatctttgaggcacaagatgcagagtataaactt
gagtttgttccaactactaccacagaatatgttcatagcttattatttcttgatgaaatt
caggaacggattgaaagccttgaagatgaggggaatatagtgactcaaatgtacaagctt
atggaacaatatcaggtgcccacacctcctgaagactttgctgtttttgcaactatgaag
ccatccattgttgctgttcggaatgccattgataaatcagtgggtgatagagaatcaagc
attaagcaattttgtgtgcatttgggtagtgatcttgaagaattaaacaacgaagtgaat
gaagtaaaactgcaagcacaggatccacagattttagatatctctgctgaccaagacaaa
ataaggctcatattgaataatctgcaatctgttctggctgatcttcagaaacgtgcattt
cagtataagtcctatcagaagaattttaaggtagaagtgtccaagtttgaagctttggaa
gaagtcagtgctgaactgaagctcaaacaattgctctgggattctttctctgaatgggat
aaactccaacaagaatggttaaagtccaaatttgattgcctggatccagaagtcctaaac
ggtcaagtttctaaatatgctaaatttgtgactcaactggaaaaaggcttgccacccaac
agtgtagtgccccagctcaaatacaaggtggaaaaaatgaaagaaaagcttccagttatc
attgacttgaggaacccgactttgaaggcaagacattgggcagctattgaacaaacagtt
gatgccactctagtggatgctgaaattccattaaccttggagaggctctcccagttgcat
gtttttgactttggtcaagaaatccaggacatatctggacaggcttctggagaagctgcc
ttagaagcaattcttaaaaaggtggaggactcttggaaaacaactgaatttgtcattctg
cctcaccgtgactccaaagatgtgtttatactgggcggcacagatgacatacaggtcctt
cttgatgatagcaccatcaatgttgcaactcttgcctcatcacgttaccttggtccactg
aaaactcgagtggatgaatggcaaaaacaacttgctttatttaatcaaacactggaagag
tggctgacctgccagagaaactggctctacctagaaagtattttcaatgctccagacatt
cagaggcaattgcctgcagaggccaagatgttccttcaggtggataagtcatggaaagaa
atcatgagaaaggtgaatcggctgcctaatgctcttcgagccgctactcagccaggactt
ctggaaacttttcaaaacaataatgcattacttgaccaaattcagaagtgcctagaggca
tacttagaatcaaaaagagttatctttccaaggttttacttcttgtcaaatgatgaactt
ctggagattttggcccagacacgaaatccacaggccgtgcagccacacttaaggaaatgc
ttcgactccatttcaaagctcgaatttgctctcatgcctcctgccgaaggaaagattcct
ggtattgatggagaaccagaaaaggtttatactaatgatattttagcaatgctgtcacca
gagggagaaagggttagcttggggaaaggcctcaaggcccgaggcaatgtagaggaatgg
cttggtaaagtggaagaagccatgttcacatctctgcgtcgcctgtgcaaagctgccatc
gctgactatcaggggaaactgaggacagactgggtggttgctggccacccttctcaagtt
atcctgactgtttctcaaattatgtggtgccgtgatttgactgaatgtctggaaacagaa
cacagtaatcatatacaggccctgaagaattttgaaaaagtaaattttgagagattaaat
gccctagctgcaatagttcaaggcagtcttcctaaattacacagaaacatcctaactgca
ttgattactattgatgtgcatgcaagagatatagtcactgaacttgttcaatccaaggtg
gagacagttgaatcttttgactggcagagacaactgcgctattactgggatatagacctg
gataattgtgtggctagaatggcgctctctcagtacacttatggctatgaatatttgggt
gcatgcccaagattggttattactccactcacagatcgctgctatctttgcctcatggga
gctttgcagcttgaccttgggggtgcaccagctggtcctgctggcactgggaaaacagag
actaccaaagatctggcaaaagctcttgccatccagtgtgtggtctttaactgttcagat
ggtttggactacaagatgatggggcgcttcttcagtggcttggcacagtcaggggcctgg
tgctgctttgatgaatttaatcgaattgacatagaagttctgtccgtcatcgcgcagcaa
ctcattaccattaggaacgccaaagcggcaaagctctctagattcatgtttgaggggcgg
gaaataaagttggtgatgacttgtgcagccttcatcacaatgaatcctggctatgcaggg
agaactgaattgccagataatttgaaagccctgtttagaccatttgcgatgatggttcca
aattatgccttgattgcagaggtaattctatattctgaaggatttgaatccagtaaaata
ttagcaagaaaaatgactcagatgtataagctttgcagtgagcagctgtctcagcaggat
cactacgactttggcatgagagctgtgaagtctgtcctggtcatggctggatctttaaaa
agagaaaacccagacctaaatgaagatgtggtgttgataagagctttacaagactccaat
ttgccaaaatttctaacagatgatgctcttctgttcagtggaatcatatctgaccttttt
cctggagtccaaattccagaacatgattatggtattttacaatcaacaattgtggatgtc
atgaatagacaaaatcttcagcctgagatgtgtatggttagaaaggtgatacagttttat
gaaactatgctagtaaggcatggtgttatgttagtcgggccaacaggaggcggcaagacc
acagtttaccgaatactagcagaaactttagggaatttacaaaaacttgggatagaaaat
tccttttaccaagcagttaaaacatatgttctcaaccctaaatcaattaccatgggtgaa
ttatatggagaggttaataacttaaccttggaatggaaagatggtttgatggcactaagt
gtccgagcagctgtgaatgatacttcagaagaccataaatggatcatcagtgatgggcca
gtagatgctctttggattgaaaacatgaatacagtgctggatgataacaagatgctttgc
ctggctaacagtgagaggattaaactcacacctcaaattcacatgctttttgaggtgcaa
gatctgcgggttgcctcccctgcaacagtcagtcgatgtggaatggtgtttgtggatcct
gaagaactgaaatggatgccttatgttaaaacttggatgaagggtatttctaaaaaactg
actgaggaaacccaagaatatatattgaatcttttccaacgttatgttgatgaaggttta
cattttatcaataaaaagtgcagccaagcaattccacaagtggacatcagcaaagttact
acactctgttgcttattggagtccttgatacttgggaaagatggagttaacttggcaatg
gaacaaacaaaattgaacactatactatgtcagacttttgtattctgttatttgtggtct
ttgggtggaaacctaactgaaaactactatgattcttttgatacatttattagaacacaa
tttgatgataatcctgatgccaggcttcccaattctggtgatctgtggagcattcatatg
gactttgacaccaaacggctggatccctgggaacgaatcatacctactttcaaatacaac
cgagatgttccattttttgaaatgcttgtccccacaactgacacagtgcgctatgggtat
ctaatggaaaaactactggcagtcaagcattccgtgttgtttactggaataactggagtg
ggcaagtctgtgattgcaaaaggattgctaaataaaattcaagaatcagctggctatgtc
cctgtttatctaaatttttctgctcaaacttcatctgcaaggacacaagagatcattgag
tcaaaactggagagaaaaagaaaaaatattctaggagcaccgggaaacaaacgaattgtg
atttttgttgatgatttaaacatgcccagactggatcgctatggctctcagcctccgatt
gaattacttcggcagtatcaagattttgggggattttatgacagaaacaaactgttttgg
aaagaaatacaggatgtaacaatcatatcggcatgtgcacctccaggcggtggccgcaac
cctgtgactccccgcttcatcagacacttcagcatgctgtgcctcccaatgccctcagag
cacagtctgaaacagatttttcaggccatcttaaatggtttcctgagtgactttccacca
gctgtaaagcaaactgcatcaagcattgtagaagcctcagttgagatttataacaaaatg
agtgttgacctcctgccaacacccgccaagtcccattatgtctttaacttgagggactta
tccaaatgtgtgcaaggtatcctccaatgtgatccaggaacaataagagaagaaattcag
atatttagactcttttgccatgagtgccaaagggtcttccatgatcgcttgattaataat
gaagataagcactatttccatgttattctgacagaaatggccaacaaacattttggaatt
gcaattgacctggaatattttttgaataagcccatcatatttggagatttcattaagttt
ggagcagataaagctgatcggatttatgatgacatgcctgatatagagaaaactgcaaat
gttctacaggactatcttgatgattataatctcacaaatcccaaagaagtaaagttggtg
ttcttccaggatgctatagaacatgtttcaaggattgctcggatgatacgtcaagaaaga
ggcaatgccctgcttgttggagtaggaggcacaggaaagcagtcactcacgagacttgca
gctcatatatgcggttacaaatgtttgcagattgaactcagccggggatataattatgat
agttttcatgaagacctgaggaagttgtacaaaatggctggtgtagaagacaagaatatg
gttttccttttcactgacacccagattgtagtggaggagttcctagaagatataaataac
atcctgaactcaggtgaagtgcctaatttatttgaaaaggatgaactggagcaggtttta
gcggccaccagaccaagagcaaaagaagtaggaatttctgaggggaacagagacgaggtg
tttcaatactttatcagcaaagtgcgtcagaagctgcacattgttctctgcatgagccca
gttggggaggcctttcggtcccgatgcaggatgtttccatcccttgtgaattgctgcacc
attgactggtttgtgcagtggcccagagaagcacttctttctgtgtcaaagacatttttc
tcacaagtcgatgctggaaatgaagaactgaaagaaaagcttcccttgatgtgcgtgaac
gttcacttgagtgtctccagcatggcagagcgctattacaatgagctgcgcaggcggtac
tacacgacacccacctcctacctggagcttatcaatctttacctgtctatgctgtctgaa
aaaaggaagcagattatttcagcacgagatcgggtgaagaatggtctcaccaagctacta
gaaacaaacatactagtagataaaatgaaactagatctttcagctttagagcctgtactt
ttagcaaaatcagaagatgttgaagccctgatggaaaaattggcagtggatcaagaaagt
gccgatcaggtccgtaacactgtgcaggaggatgaagcaacagcaaaagtcaaagctgaa
gaaacccaagcaatagctgatgatgctcaaagagatcttgacgaggcactacctgcacta
gatgctgccaataaagcactggattccttagataaggcagatatatctgaaatcagagtt
tttacaaagcccccagatttggtcatgacagtaatggaagcaatctccattcttttgaat
gccaagcctgattggccatcagcaaagcaacttcttggtgactctaactttctaaaaagg
cttttagaatatgataaggagaacataaagcctcagatattggcaaagcttcaaaagtat
attaataatcctgattttgtgcctgaaaaagtggagaaagtgtccaaagcatgtaaatct
atgtgcatgtgggtaagagctatggatttgtactctcgagtggtcaaggtcgtcgaacca
aaaagacaaaagctccgcgccgcacaggctgaacttgacattaccatggctaccctgaga
gaaaagcaagcattactaagacaagtagaagatcaaatacaggccttacaagatgaatat
gacaaaggtgtaaatgaaaaagaaagcctggcaaagaccatggccctgacaaaagcacgt
ctagtacgtgctggaaagctgacagcagcattagaagatgagcaggttcgatgggaagaa
agcatacagaagtttgaggaagaaatatcaaatatcactgggaacgtgttcatagcagca
gcttgtgtggcctactatggggctttcacagcccagtacaggcagtcacttatagagtgt
tggatccaggactgtcagtctctggagatcccaatcgatccttccttcagtctcattaac
attcttggagatccctacgagatacggcagtggaacactgatgggctgccccgtgacttg
atatcaacagaaaatggcattttggttactcaaggcagaagatggcctttgatgattgat
ccccaagatcaggcaaaccgttggataaggaacaaggaaagcaaaagtggtttaaagatc
attaagcttacagatagtaatttcttacgaatactcgagaattcaatccgacttggttta
cctgtcttactggaagagcttaaggaaaccttggatccagctctagaacccattcttttg
aaacaaatttttatcagtggtggccgactactcatccgtcttggagactcagacattgat
tatgacaaaaactttaggttctatatgacaaccaaaatgccaaatccccactatctgcct
gaggtatgcattaaagttaccattatcaatttcactgtaacaaaatcaggcctggaggat
cagttgttaagtgatgtggtgcgacttgaaaaacccaggttggaagaacaaagaattaag
ctcatcgtgaggatcaacactgataaaaaccagttgaaaactatcgaagagaaaatcctg
agaatgctctttacctctgaaggaaatattctggacaatgaagaacttattgacacactc
caggattcaaagatcacttctggtgccattaaaaccaggctggaagaagcagagtccact
gagcagatgatcaatgtggctcgtgagaagtatcgtccagtggccactcaaggctctgta
atgtactttgtcattgcaagcctctcagaaatagatcctatgtaccagtactcattaaaa
tactttaaacagttgttcaataccaccattgaaacttctgtaaagacagaaaatctacaa
cagcgcctggacgtactactagaacaaactctcctaactgcttatgtcaatgtttcaaga
ggactttttgagcaacataaactcatctacagctttatgctttgtgttgagatgatgcgt
cagcaaggaaccctatctgatgctgaatggaatttctttctccgaggttctgcaggattg
gaaaaggaacgcccacctaagcctgaagctccctggctacctactgctacatggttcgca
tgctgtgacttggaagaatcatttccagtttttcacggacttacccaaaatatattgtca
catcctatttccatacgcttaggatcttttgagacttatattaacccacagaaatgggaa
ggctattctaaaatgaaacacgaagataaacacatgagacaggaaaaggaggcagcacac
caagatccatggagtgcaggattgagttctttccataagctaattcttattaaatgttgt
aaagaagaaaaggtggtttttgctcttacagactttgtgatagaaaatcttggaaaacag
tttatagagacaccacctgtggacctgcctaccctgtatcaagacatgtcatgcaacact
cccctggtattcatcctaagcacaggctcagatcccatgggtgcatttcagaggtttgcc
agggaaagtggatattcagaacgggtgcagtcaatttcactggggcaaggacaaggacct
attgctgaaaaaatggtcaaggatgcaatgaaatcaggaaactgggtatttttgcaaaat
tgccatcttgctgtttcttggatgttggcaatggaagagctcattaaaaccttcacagat
ccagatagtgctatcaaggacacttttcgactttttttaagctccatgcctagtaataca
tttcctgttacagttcttcaaaattctgtcaaggtgaccaatgagcctccaaaaggctta
cgtgcaaatatcagacgagcatttactgaaatgacaccttcgttttttgaagaaaatata
cttggaaaaaaatggagacaaataatatttggcatttgtttcttccatgcaattattcag
gagagaaagaagtttggcccccttggttggaatatctgctatgaatttaatgacagtgac
agggaatgtgctttactgaatctcaaactctattgtaaagaaggaaagattccctgggat
gcactaatttacattactggtgaaattacttatggtggtagagtcacagacagctgggac
caaagatgccttcgtactatcttgaaaagatttttttctcctgaaacattagaagaagat
tataaatactctgaatcaggcatctattttgcacccatggctgacagcctacaagagttt
aaggactacattgaaaatctgcctttgatcgatgacccagaaatttttggaatgcatgaa
aatgctaatctagtcttccagtacaaagagaccagcactttaatcaacaccatacttgag
gttcagccaaggtcatctactggtggagagggaaaaagcaatgacgaaattgttcaagaa
cttgttgcttctgtccagaccagagttccagaaaaactggaaatggagggtgcttctgag
agcctttttgtcaaggatcttcaaggacgtctgaactccttgaccaccgttcttggacag
gaagtggaccggtttaacaacctgctgaagttaattcatacttctctggaaacactcaac
aaagccatcgctggatttgtggtgatgtctgaagaaatggaaaaagtgtataacagtttc
ctcaacaaccaggttcccgctctgtggtccaacacagcctacccatccctgaagccacta
ggatcatgggtcaaagaccttatcctgaggacctcatttgtggatctgtggctcaaaaga
ggacagcctaagtcctactggatctctggtttcttctttcctcaaggatttctaacagga
actcttcaaaatcatgctcgaaaatacaatttgcctatagatgagctgagtttcaaatac
agcgtaattcccacctatcgggatcaagctgcagtgatagaagctgccaagacagtgcaa
tttggacaagaactgcccatggacatggagttgccctctcctgaggatggtgttcttgtt
catgggatgttcatggatgcttctcgatgggatgataaggagatggtgatagaagatgca
ttgcccggacagatgaatccagtgctgcctgtggtgcattttgaaccacaacaaaactat
aagccaagcccaacactttaccactgcccactttataaaacaggagcccgggcaggaaca
ctctcaaccacaggacattcaaccaattttgtggtaaccgtcctgttaccctccaagcgg
tccaaagactactggattgccaagggatcagctttgctctgccagctgagcgaatga

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