KEGG   Homo sapiens (human): 1780
Entry
1780              CDS       T01001                                 
Symbol
DYNC1I1, DNCI1, DNCIC1
Name
(RefSeq) cytoplasmic dynein 1 intermediate chain 1 isoform a
  KO
K10415  dynein cytoplasmic 1 intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    1780 (DYNC1I1)
  09142 Cell motility
   04814 Motor proteins
    1780 (DYNC1I1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1780 (DYNC1I1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1780 (DYNC1I1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1780 (DYNC1I1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1780 (DYNC1I1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1780 (DYNC1I1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1780 (DYNC1I1)
SSDB
Motif
Pfam: Beta-prop_THOC3 Beta-prop_IFT122_1st WD40_CDC20-Fz WD40 WDR55 Beta-prop_WDR5 Dynein_IC2 Beta-prop_EML Beta-prop_WDR3_1st WD40_Prp19 Beta-prop_WDR36-Utp21_1st DNAI3_WD Beta-prop_EML_2 PAC11 WD40_WDHD1_1st Beta-prop_RIG_2nd Beta-prop_WDR19_1st EIF3I Beta-prop_HPS5 Beta-prop_NOL10_N Beta-prop_TEP1_2nd Beta-prop_WDR90_POC16_2nd Beta-prop_TEP1_C Beta-prop_WDR3_2nd WD40_MABP1-WDR62_2nd Beta-prop_EIPR1 ASA1 WD40_RFWD3 Tricorn_2nd CFAP43_N Beta-prop_DCAF4
Other DBs
NCBI-GeneID: 1780
NCBI-ProteinID: NP_004402
OMIM: 603772
HGNC: 2963
UniProt: O14576 A4D1I7 Q8N542
LinkDB
Position
7:95772554..96110322
AA seq 645 aa
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL
TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
NT seq 1938 nt   +upstreamnt  +downstreamnt
atgtctgacaaaagtgacttaaaagctgagctagagcgcaaaaagcagcgcttagcacag
ataagagaagagaagaaacggaaggaagaggagaggaaaaagaaagaggctgatatgcag
cagaagaaagaacccgttcaggacgactctgatctggatcgcaaacgacgagagacagag
gctttgctgcaaagcattggtatctcaccggagccgcctctagtgcagccgctgcatttt
ttaacatgggatacctgttattttcattatttagtcccaacccctatgtctccctcctcg
aaatcagtgagcactcccagtgaagctggaagccaagactcaggcgatctggggccatta
acaaggaccctgcagtgggacacagacccctcagtgctccagctgcagtcagactcagaa
cttggaagaagactgcataaactgggcgtgtcaaaggtcacccaagtggatttcctgcca
agggaagtagtgtcctactcaaaggagacccagactcctcttgccacgcatcagtctgaa
gaggatgaggaagatgaggaaatggtggaatctaaagttggccaggactcagaactggaa
aatcaggacaaaaaacaggaagtgaaggaagcccctccaagagagttgacagaggaagaa
aaacagcagatccttcattcagaggaatttctcatcttttttgaccggacaatacgggta
attgaaagagccctggctgaagattccgacatcttttttgactacagcggccgagagtta
gaggaaaaagatggggatgttcaggctggagccaatctttctttcaatcgtcagttctat
gatgaacattggtccaagcatcgagtggtcacttgtatggactggtccctccagtaccct
gagctgatggtggcttcttacaacaacaatgaagatgctccccatgaaccagatggagtg
gccttggtttggaacatgaagtttaagaaaaccacaccagaatacgtcttccactgtcag
tcctctgtgatgtcggtctgcttcgcccgtttccatcctaacttggtggttggtgggact
tactcgggccagattgtcctctgggacaatcgcagtcatcgaaggactccagtgcagcgg
acacccttatcagctgctgcacacacgcatcccgtgtactgtgtaaatgttgttgggacc
cagaatgctcataacctcatcactgtctccactgatggcaaaatgtgttcctggagcctg
gacatgctctcaactccacaggagagcatggagctggtgtacaataagtccaagcctgtc
gctgttaccggaatggctttcccaacgggagacgtcaataacttcgtggttggcagtgag
gaaggtacagtctacacggcttgtcgtcatggaagcaaagcaggtattggtgaggtcttt
gaaggtcaccaagggccagtgacaggaattaactgccacatggcagtgggcccaatcgac
ttttctcacctgtttgtcacatcatcatttgactggactgtcaaactgtggaccaccaag
cacaacaagccgctctactcctttgaagacaatgcagactatgtgtacgatgtcatgtgg
tcccccgtgcatcctgcgctttttgcctgcgtggacgggatggggcgcttggacctctgg
aacctcaacaatgacaccgaggttccaacagcaagtgtggccattgagggggcatccgcc
ctaaaccgtgttcgttgggcccaagctggcaaagaagttgctgttggggactcggaaggc
cgtatttgggtctatgacgttggagagcttgcagttccccacaatgatgaatggacccga
tttgccaggacccttgtggaaattcgtgctaacagagctgatagcgaggaggaaggcact
gttgagttatctgcctag

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