KEGG   Homo sapiens (human): 1783
Entry
1783              CDS       T01001                                 
Symbol
DYNC1LI2, DNCLI2, LIC2
Name
(RefSeq) dynein cytoplasmic 1 light intermediate chain 2
  KO
K10416  dynein cytoplasmic 1 light intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1783 (DYNC1LI2)
  09142 Cell motility
   04814 Motor proteins
    1783 (DYNC1LI2)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1783 (DYNC1LI2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1783 (DYNC1LI2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1783 (DYNC1LI2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    1783 (DYNC1LI2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1783 (DYNC1LI2)
Membrane trafficking [BR:hsa04131]
 Protein recycling
  Rab GTPases and associated proteins
   Rab4 associated proteins
    1783 (DYNC1LI2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1783 (DYNC1LI2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1783 (DYNC1LI2)
SSDB
Motif
Pfam: DLIC ABC_tran AAA_16 Arf AAA_7 AAA_22 PduV-EutP AAA_29 NACHT ATPase nSTAND3 Roc nSTAND6 AAA_25 AAA_14 SRP54
Other DBs
NCBI-GeneID: 1783
NCBI-ProteinID: NP_006132
OMIM: 611406
HGNC: 2966
Ensembl: ENSG00000135720
UniProt: O43237 Q63HJ8
Structure
LinkDB
Position
16:complement(66720893..66751609)
AA seq 492 aa
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVF
GEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLK
FAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVL
EKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPA
LVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIK
NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPD
SMVTNSSTENEA
NT seq 1479 nt   +upstreamnt  +downstreamnt
atggcgccggtgggggtggagaagaagctgctgctaggtcccaacgggcccgcggtggcg
gccgccggcgacctgaccagtgaggaggaggaaggccagagcctatggtcctccattctg
agcgaagtgtccacccgcgccaggtccaagctgccgtccggcaagaacatcctggtcttc
ggtgaagatggttctggtaaaacaaccctcatgactaaactacaaggagctgagcatggc
aaaaaaggaagaggcctagaatatctctacctcagtgtccatgatgaggaccgagatgat
cacacgcgctgcaacgtgtggattctggatggagacttgtaccacaaaggcctgctgaaa
tttgcagtttctgctgaatccttgccagagaccctcgtcatttttgttgcagacatgtct
agaccttggactgtgatggaatctctgcagaaatgggctagtgttttacgtgagcacatt
gataaaatgaaaattccaccagaaaaaatgagggagctggaacggaagtttgtgaaagat
tttcaagactatatggaacctgaagaaggttgtcaaggttccccacagagaagaggccct
ctgacctcaggctccgatgaagaaaatgttgccctgcctctgggtgacaatgtgctgact
cataacctggggatcccggtgttggtggtgtgcacaaagtgtgatgcggtgagtgtcctg
gagaaggagcacgattacagggatgagcatttggactttatccagtcacacctgcggagg
ttctgccttcagtatggagctgccttgatttacacatcagtgaaagaagagaaaaacctc
gacttgttgtataagtatattgttcataaaacatacggtttccacttcaccacacctgcc
ttagttgtggaaaaggatgccgtttttatacctgcaggctgggacaatgaaaagaaaata
gctattttacatgaaaattttacaaccgtgaagccggaagatgcatatgaagactttatt
gtgaaacctcccgtgagaaagctggtccacgacaaagagttggcagcagaagatgagcag
gtgttcctaatgaagcaacagtcactccttgccaagcaaccagccactcccacgagagct
tctgaatctcctgcaagaggaccctctggctctccaaggacccagggtcggggagggcca
gccagtgtgcctagctcctccccaggcacgtcagtaaaaaagccggacccaaacatcaaa
aataatgcagcaagtgaaggggtgttggccagcttcttcaacagtctgttgagtaaaaag
acaggctctcctggaagtcctggtgctggtggggtgcagagcacagccaagaagtcagga
caaaagactgtgttgtcaaatgttcaggaagaactggatagaatgactcgaaagccagac
tctatggtaacaaactcttcaacagaaaatgaagcctga

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