Homo sapiens (human): 1807 Help Entry 1807              CDS       T01001                                  Symbol DPYS, DHP, DHPase Name (RefSeq) dihydropyrimidinase   KO K01464   dihydropyrimidinase [EC:3.5.2.2] Organism hsa  Homo sapiens (human) Pathway hsa00240   Pyrimidine metabolism hsa00410   beta-Alanine metabolism hsa00770   Pantothenate and CoA biosynthesis hsa00983   Drug metabolism - other enzymes hsa01100   Metabolic pathways Module hsa_M00046   Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate Disease H00199   Dihydropyrimidinase deficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     1807 (DPYS)   09106 Metabolism of other amino acids    00410 beta-Alanine metabolism     1807 (DPYS)   09108 Metabolism of cofactors and vitamins    00770 Pantothenate and CoA biosynthesis     1807 (DPYS)   09111 Xenobiotics biodegradation and metabolism    00983 Drug metabolism - other enzymes     1807 (DPYS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     1807 (DPYS) Enzymes [BR:hsa01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.2  In cyclic amides     3.5.2.2  dihydropyrimidinase      1807 (DPYS) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    1807 (DPYS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Amidohydro_1 Amidohydro_3 Amidohydro_2 Motif Other DBs NCBI-GeneID:  1807 NCBI-ProteinID:  NP_001376 OMIM:  613326 HGNC:  3013 Ensembl:  ENSG00000147647 Vega:  OTTHUMG00000164891 Pharos:  Q14117(Tbio) UniProt:  Q14117 Structure PDB LinkDB All DBs Position 8:complement(104379431..104467055) Genome browser AA seq 519 aa AA seqDB search MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP NT seq 1560 nt NT seq  +upstreamnt  +downstreamnt atggcggcgccctcgcggctcctgatccgcgggggtcgcgtggtcaacgatgacttctcg gaggtggccgacgtgctggtggaggacggcgtggtgcgggcactcgggcacgacctgctg cctcccgggggcgctcctgcggggctgcgggtcctcgacgccgccggcaagctcgtcctg cccggaggcatcgacacacacacgcacatgcagttccccttcatgggctcgcggtccatc gacgacttccaccagggcaccaaggctgctctctcaggaggcaccaccatgattattgat ttcgccattcctcagaaaggtggctccctcattgaggccttcgagacctggcgaagctgg gctgatcccaaagtttgctgcgactacagccttcatgtggcagtgacgtggtggagtgac caggttaaagaagaaatgaaaatccttgtgcaagataaaggtgttaactctttcaagatg tttatggcctataaagatctgtacatggtgacagacctggagctgtacgaagccttctct cggtgcaaggaaattggagcaattgcccaggtccatgcggaaaatggagacttaattgca gagggagcaaagaagatgttggctctggggataacaggccctgagggccacgagctgtgc cgcccagaggcagtggaggcagaggccacgctgagagccatcaccatagccagcgctgtg aactgtcctctctacattgtgcatgtgatgagcaagtctgcagctaaggtgatagcggat gcaaggagagatgggaaggtggtctatggtgaacccatagcagccagtcttggcacagat ggcactcactactggaataaagaatggcaccatgcagcccaccatgtcatgggtccacct ttgcgaccagacccctcaacacccgacttcctcatgaatctgttggctaatgatgatcta accacaacagggactgataactgcactttcaacacctgccagaaagctcttgggaaggat gattttaccaagatccccaatggggtgaatggtgttgaagatcggatgtccgtaatatgg gaaaaaggcgtgcatagtggtaaaatggatgaaaacagatttgtggcagttaccagcaca aatgcagccaaaatttttaatctctatccaagaaaaggaagaatagctgtaggatcagat gctgacattgttatttgggacccaaaaggcacaaggactatctcagcaaaaactcatcat caggctgttaacttcaacattttcgagggcatggtttgccacggggtgccccttgtgact atttcaagaggcaaagtggtatatgaagccggagtgttcagtgtcacggcaggagatggg aagtttattcctcgaaaaccatttgctgaatatatttacaaacgaataaagcagcgagac cggacttgcacacctacccctgtggagcgtgcaccctataagggagaagtcgccacactg aaatccagagtgacaaaagaagatgccacagcagggaccaggaaacaggcccacccctga

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