Homo sapiens (human): 1975
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Entry
1975 CDS
T01001
Symbol
EIF4B, EIF-4B, PRO1843
Name
(RefSeq) eukaryotic translation initiation factor 4B
KO
K03258
translation initiation factor 4B
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
1975 (EIF4B)
04150 mTOR signaling pathway
1975 (EIF4B)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
1975 (EIF4B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
1975 (EIF4B)
03012 Translation factors [BR:
hsa03012
]
1975 (EIF4B)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
eIF4F and regulatory proteins
1975 (EIF4B)
mRNA cycle factors
Stress granule specific factors
1975 (EIF4B)
Translation factors [BR:
hsa03012
]
Eukaryotic type
Initiation factors
eIF-4
1975 (EIF4B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RRM_1
RRM_7
Motif
Other DBs
NCBI-GeneID:
1975
NCBI-ProteinID:
NP_001408
OMIM:
603928
HGNC:
3285
Ensembl:
ENSG00000063046
UniProt:
P23588
Structure
PDB
PDBj
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All DBs
Position
12:53006456..53042215
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AA seq
611 aa
AA seq
DB search
MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
EDENEGEDYAE
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atggcggcctcagcaaaaaagaagaataagaaggggaagactatctccctaacagacttt
ctggctgaggatgggggtactggtggaggaagcacctatgtttccaaaccagtcagctgg
gctgatgaaacggatgacctggaaggagatgtttcgaccacttggcacagtaacgatgac
gatgtgtatagggcgcctccaattgaccgttccatccttcccactgctccacgggctgct
cgggaacccaatatcgaccggagccgtcttcccaaatcgccaccctacactgcttttcta
ggaaacctaccctatgatgttacagaagagtcaattaaggaattctttcgaggattaaat
atcagtgcagtgcgtttaccacgtgaacccagcaatccagagaggttgaaaggttttggt
tatgctgaatttgaggacctggattccctgctcagtgccctgagtctcaatgaagagtct
ctaggtaacaggagaattcgagtggacgttgctgatcaagcacaggataaagacagggat
gatcgttcttttggccgtgatagaaatcgggattctgacaaaacagatacagactggagg
gctcgtcctgctacagacagctttgatgactacccacctagaagaggtgatgatagcttt
ggagacaagtatcgagatcgttatgattcagaccggtatcgggatgggtatcgggatggg
tatcgggatggcccacgccgggatatggatcgatatggtggccgggatcgctatgatgac
cgaggcagcagagactatgatagaggctatgattcccggataggcagtggcagaagagca
tttggcagtgggtatcgcagggatgatgactacagaggaggcggggaccgctatgaagac
cgatatgacagacgggatgatcggtcgtggagctccagagatgattactctcgggatgat
tataggcgtgatgatagaggtcccccccaaagacccaaactgaatctaaagcctcggagt
actcctaaggaagatgattcctctgctagtacctcccagtccactcgagctgcttctatc
tttggaggggcaaagcctgttgacacagctgctagagaaagagaagtagaagaacggcta
cagaaggaacaagagaagttgcagcgtcagctggatgagccaaaactagaacgacggcct
cgggagagacacccaagctggcgaagtgaagaaactcaggaacgggaacggtcgaggaca
ggaagtgagtcatcacaaactgggacctccaccacatctagcagaaatgcacgaaggaga
gagagtgagaagtctctagaaaatgaaacactcaataaggaggaagattgccactctcca
acttctaaacctcccaaacctgatcagcccctaaaggtaatgccagcccctccaccaaag
gagaatgcttgggtgaagcgaagttctaaccctcctgctcgatctcagagctcagacaca
gagcagcagtcccctacaagtggtgggggaaaagtagctccagctcaaccatctgaggaa
ggaccaggaaggaaagatgaaaataaagtagatgggatgaatgccccaaaaggccaaact
gggaactctagccgtggtccaggcgacggagggaacagagaccactggaaggagtcagat
aggaaagatggcaaaaaggatcaagactccagatctgcacctgagccaaagaaacctgag
gaaaatccagcttccaagttcagttctgcaagcaagtatgctgctctctctgttgatggt
gaagatgaaaatgagggagaagattatgccgaatag
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