Homo sapiens (human): 2
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Entry
2 CDS
T01001
Symbol
A2M, A2MD, CPAMD5, FWP007, S863-7
Name
(RefSeq) alpha-2-macroglobulin
KO
K03910
alpha-2-macroglobulin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
2 (A2M)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
2 (A2M)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
2 (A2M)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
2 (A2M)
Peptidases and inhibitors [BR:
hsa01002
]
Peptidase inhibitors
Family I39: alpha2M family
2 (A2M)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
2 (A2M)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
2 (A2M)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TED_complement
A2M_BRD
A2M
MG4
A2M_recep
MG3
MG2
SVA
MG1
Big_1
MP
Motif
Other DBs
NCBI-GeneID:
2
NCBI-ProteinID:
NP_000005
OMIM:
103950
HGNC:
7
Ensembl:
ENSG00000175899
UniProt:
P01023
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(9067708..9116229)
Genome browser
AA seq
1474 aa
AA seq
DB search
MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV
SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV
MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS
FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT
ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF
YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR
QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT
VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY
ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL
LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV
DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSS
TNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARL
VHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGI
SSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVE
KEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVI
KPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQ
NTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKH
YDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCF
RSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDH
GSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQ
APSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHA
LSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEG
CVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAI
VDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVR
DLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA
NT seq
4425 nt
NT seq
+upstream
nt +downstream
nt
atggggaagaacaaactccttcatccaagtctggttcttctcctcttggtcctcctgccc
acagacgcctcagtctctggaaaaccgcagtatatggttctggtcccctccctgctccac
actgagaccactgagaagggctgtgtccttctgagctacctgaatgagacagtgactgta
agtgcttccttggagtctgtcaggggaaacaggagcctcttcactgacctggaggcggag
aatgacgtactccactgtgtcgccttcgctgtcccaaagtcttcatccaatgaggaggta
atgttcctcactgtccaagtgaaaggaccaacccaagaatttaagaagcggaccacagtg
atggttaagaacgaggacagtctggtctttgtccagacagacaaatcaatctacaaacca
gggcagacagtgaaatttcgtgttgtctccatggatgaaaactttcaccccctgaatgag
ttgattccactagtatacattcaggatcccaaaggaaatcgcatcgcacaatggcagagt
ttccagttagagggtggcctcaagcaattttcttttcccctctcatcagagcccttccag
ggctcctacaaggtggtggtacagaagaaatcaggtggaaggacagagcaccctttcacc
gtggaggaatttgttcttcccaagtttgaagtacaagtaacagtgccaaagataatcacc
atcttggaagaagagatgaatgtatcagtgtgtggcctatacacatatgggaagcctgtc
cctggacatgtgactgtgagcatttgcagaaagtatagtgacgcttccgactgccacggt
gaagattcacaggctttctgtgagaaattcagtggacagctaaacagccatggctgcttc
tatcagcaagtaaaaaccaaggtcttccagctgaagaggaaggagtatgaaatgaaactt
cacactgaggcccagatccaagaagaaggaacagtggtggaattgactggaaggcagtcc
agtgaaatcacaagaaccataaccaaactctcatttgtgaaagtggactcacactttcga
cagggaattcccttctttgggcaggtgcgcctagtagatgggaaaggcgtccctatacca
aataaagtcatattcatcagaggaaatgaagcaaactattactccaatgctaccacggat
gagcatggccttgtacagttctctatcaacaccaccaatgttatgggtacctctcttact
gttagggtcaattacaaggatcgtagtccctgttacggctaccagtgggtgtcagaagaa
cacgaagaggcacatcacactgcttatcttgtgttctccccaagcaagagctttgtccac
cttgagcccatgtctcatgaactaccctgtggccatactcagacagtccaggcacattat
attctgaatggaggcaccctgctggggctgaagaagctctccttctattatctgataatg
gcaaagggaggcattgtccgaactgggactcatggactgcttgtgaagcaggaagacatg
aagggccatttttccatctcaatccctgtgaagtcagacattgctcctgtcgctcggttg
ctcatctatgctgttttacctaccggggacgtgattggggattctgcaaaatatgatgtt
gaaaattgtctggccaacaaggtggatttgagcttcagcccatcacaaagtctcccagcc
tcacacgcccacctgcgagtcacagcggctcctcagtccgtctgcgccctccgtgctgtg
gaccaaagcgtgctgctcatgaagcctgatgctgagctctcggcgtcctcggtttacaac
ctgctaccagaaaaggacctcactggcttccctgggcctttgaatgaccaggacaatgaa
gactgcatcaatcgtcataatgtctatattaatggaatcacatatactccagtatcaagt
acaaatgaaaaggatatgtacagcttcctagaggacatgggcttaaaggcattcaccaac
tcaaagattcgtaaacccaaaatgtgtccacagcttcaacagtatgaaatgcatggacct
gaaggtctacgtgtaggtttttatgagtcagatgtaatgggaagaggccatgcacgcctg
gtgcatgttgaagagcctcacacggagaccgtacgaaagtacttccctgagacatggatc
tgggatttggtggtggtaaactcagcaggtgtggctgaggtaggagtaacagtccctgac
accatcaccgagtggaaggcaggggccttctgcctgtctgaagatgctggacttggtatc
tcttccactgcctctctccgagccttccagcccttctttgtggagctcacaatgccttac
tctgtgattcgtggagaggccttcacactcaaggccacggtcctaaactaccttcccaaa
tgcatccgggtcagtgtgcagctggaagcctctcccgccttcctagctgtcccagtggag
aaggaacaagcgcctcactgcatctgtgcaaacgggcggcaaactgtgtcctgggcagta
accccaaagtcattaggaaatgtgaatttcactgtgagcgcagaggcactagagtctcaa
gagctgtgtgggactgaggtgccttcagttcctgaacacggaaggaaagacacagtcatc
aagcctctgttggttgaacctgaaggactagagaaggaaacaacattcaactccctactt
tgtccatcaggtggtgaggtttctgaagaattatccctgaaactgccaccaaatgtggta
gaagaatctgcccgagcttctgtctcagttttgggagacatattaggctctgccatgcaa
aacacacaaaatcttctccagatgccctatggctgtggagagcagaatatggtcctcttt
gctcctaacatctatgtactggattatctaaatgaaacacagcagcttactccagagatc
aagtccaaggccattggctatctcaacactggttaccagagacagttgaactacaaacac
tatgatggctcctacagcacctttggggagcgatatggcaggaaccagggcaacacctgg
ctcacagcctttgttctgaagacttttgcccaagctcgagcctacatcttcatcgatgaa
gcacacattacccaagccctcatatggctctcccagaggcagaaggacaatggctgtttc
aggagctctgggtcactgctcaacaatgccataaagggaggagtagaagatgaagtgacc
ctctccgcctatatcaccatcgcccttctggagattcctctcacagtcactcaccctgtt
gtccgcaatgccctgttttgcctggagtcagcctggaagacagcacaagaaggggaccat
ggcagccatgtatataccaaagcactgctggcctatgcttttgccctggcaggtaaccag
gacaagaggaaggaagtactcaagtcacttaatgaggaagctgtgaagaaagacaactct
gtccattgggagcgccctcagaaacccaaggcaccagtggggcatttttacgaaccccag
gctccctctgctgaggtggagatgacatcctatgtgctcctcgcttatctcacggcccag
ccagccccaacctcggaggacctgacctctgcaaccaacatcgtgaagtggatcacgaag
cagcagaatgcccagggcggtttctcctccacccaggacacagtggtggctctccatgct
ctgtccaaatatggagcagccacatttaccaggactgggaaggctgcacaggtgactatc
cagtcttcagggacattttccagcaaattccaagtggacaacaacaaccgcctgttactg
cagcaggtctcattgccagagctgcctggggaatacagcatgaaagtgacaggagaagga
tgtgtctacctccagacatccttgaaatacaatattctcccagaaaaggaagagttcccc
tttgctttaggagtgcagactctgcctcaaacttgtgatgaacccaaagcccacaccagc
ttccaaatctccctaagtgtcagttacacagggagccgctctgcctccaacatggcgatc
gttgatgtgaagatggtctctggcttcattcccctgaagccaacagtgaaaatgcttgaa
agatctaaccatgtgagccggacagaagtcagcagcaaccatgtcttgatttaccttgat
aaggtgtcaaatcagacactgagcttgttcttcacggttctgcaagatgtcccagtaaga
gatctgaaaccagccatagtgaaagtctatgattactacgagacggatgagtttgcaatt
gctgagtacaatgctccttgcagcaaagatcttggaaatgcttga
DBGET
integrated database retrieval system
