Homo sapiens (human): 200734
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Entry
200734 CDS
T01001
Symbol
SPRED2, NS14, Spred-2
Name
(RefSeq) sprouty related EVH1 domain containing 2
KO
K04703
sprouty-related, EVH1 domain-containing protein
Organism
hsa
Homo sapiens (human)
Network
nt06526
MAPK signaling
Element
N01597
Regulation of GF-RTK-RAS-ERK signaling, SPRED and NF1
Disease
H01738
Noonan syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
200734 (SPRED2)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
200734 (SPRED2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sprouty
WH1
Motif
Other DBs
NCBI-GeneID:
200734
NCBI-ProteinID:
NP_861449
OMIM:
609292
HGNC:
17722
Ensembl:
ENSG00000198369
UniProt:
Q7Z698
B3KPL5
Structure
PDB
PDBj
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All DBs
Position
2:complement(65307175..65432599)
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AA seq
418 aa
AA seq
DB search
MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIH
GERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIE
DLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTL
GHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKY
PDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRR
KEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD
YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaagaaacacacccagacgatgacagctatattgtgcgtgtcaaggctgtggtt
atgaccagagatgactccagcgggggatggttcccacaggaaggaggcgggatcagtcgc
gtcggggtctgtaaggtcatgcaccccgaaggcaatggacgaagcggctttctcatccat
ggtgaacgacagaaagacaaactggtggtattggaatgctatgtaagaaaggacttggtc
tacaccaaagccaatccaacgtttcatcactggaaggtcgataataggaagtttggactt
actttccaaagccctgctgatgcccgagcctttgacaggggagtaaggaaagcaatcgaa
gaccttatagaaggttcaacaacgtcatcttccaccatccataatgaagctgagcttggc
gatgatgacgtttttacaacagctacagacagttcttctaattcctctcagaagagagag
caacctactcggacaatctcctctcccacatcctgtgagcaccggaggatttataccctg
ggccacctccacgactcataccccacagaccactatcacctcgatcagccgatgccaagg
ccctaccgccaggtgagcttcccggacgacgacgaggagatcgtgcgcatcaacccccgg
gagaagatctggatgacggggtacgaggattaccggcacgcacccgtcaggggcaagtac
ccggacccctcggaggacgcggactcctcctacgtgcgcttcgccaagggcgaggtcccc
aagcatgactacaactacccctacgtggactcctcagactttggcctaggcgaggacccc
aaaggccgcgggggcagcgtgatcaagacgcagccctcccggggcaagtcgcggcggcgg
aaggaggacggagagcgctcgcggtgcgtgtactgcagggacatgttcaaccacgaggag
aaccgccggggccactgccaggacgcgcccgactccgtgagaacttgcatccgccgggtg
agctgcatgtggtgcgcggacagcatgctctatcactgtatgtcggaccccgagggagac
tatacagacccttgctcgtgcgatactagcgacgagaagttttgcctccggtggatggct
cttattgccttgtctttcctggccccctgtatgtgctgttacctgccccttcgggcctgc
taccactgcggagtgatgtgcaggtgctgtggcgggaagcacaaagcggccgcgtga
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