Homo sapiens (human): 2011
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Entry
2011 CDS
T01001
Symbol
MARK2, EMK-1, EMK1, MRD76, PAR-1, Par-1b, Par1b
Name
(RefSeq) microtubule affinity regulating kinase 2
KO
K08798
MAP/microtubule affinity-regulating kinase [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
2011 (MARK2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
2011 (MARK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
2011 (MARK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMKL family
2011 (MARK2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Others
2011 (MARK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
KA1
UBA
Kinase-like
ABC1
UBA_SIK3
UBA_2
UBA_MELK
Haspin_kinase
Kdo
Motif
Other DBs
NCBI-GeneID:
2011
NCBI-ProteinID:
NP_001034558
OMIM:
600526
HGNC:
3332
Ensembl:
ENSG00000072518
UniProt:
Q7KZI7
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:63839110..63911020
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AA seq
788 aa
AA seq
DB search
MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTS
NSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTST
NRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHP
NKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAG
QLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPE
SKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDA
NSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIAS
KIANELKL
NT seq
2367 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcgctcggacccccctacccacgctgaacgagagggacacggagcagcccacc
ttgggacaccttgactccaagcccagcagtaagtccaacatgattcggggccgcaactca
gccacctctgctgatgagcagccccacattggaaactaccggctcctcaagaccattggc
aagggtaattttgccaaggtgaagttggcccgacacatcctgactgggaaagaggtagct
gtgaagatcattgacaagactcaactgaactcctccagcctccagaaactattccgcgaa
gtaagaataatgaaggttttgaatcatcccaacatagttaaattatttgaagtgattgag
actgagaaaacgctctaccttgtcatggagtacgctagtggcggagaggtatttgattac
ctagtggctcatggcaggatgaaagaaaaagaggctcgagccaaattccgccagatagtg
tctgctgtgcagtactgtcaccagaagtttattgtccatagagacttaaaggcagaaaac
ctgctcttggatgctgatatgaacatcaagattgcagactttggcttcagcaatgaattc
acctttgggaacaagctggacaccttctgtggcagtcccccttatgctgccccagaactc
ttccagggcaaaaaatatgatggacccgaggtggatgtgtggagcctaggagttatcctc
tatacactggtcagcggatccctgccttttgatggacagaacctcaaggagctgcgggaa
cgggtactgaggggaaaataccgtattccattctacatgtccacggactgtgaaaacctg
cttaagaaatttctcattcttaatcccagcaagagaggcactttagagcaaatcatgaaa
gatcgatggatgaatgtgggtcacgaagatgatgaactaaagccttacgtggagccactc
cctgactacaaggacccccggcggacagagctgatggtgtccatgggttatacacgggaa
gagatccaggactcgctggtgggccagagatacaacgaggtgatggccacctatctgctc
ctgggctacaagagctccgagctggaaggcgacaccatcaccctgaaaccccggccttca
gctgatctgaccaatagcagcgccccatccccatcccacaaggtacagcgcagcgtgtcg
gccaatcccaagcagcggcgcttcagcgaccaggcagctggtcctgccattcccacctct
aattcttactctaagaagactcagagtaacaacgcagaaaataagcggcctgaggaggac
cgggagtcagggcggaaagccagcagcacagccaaggtgcctgccagccccctgcccggt
ctggagaggaagaagaccaccccaaccccctccacgaacagcgtcctctccaccagcaca
aatcgaagcaggaattccccacttttggagcgggccagcctcggccaggcctccatccag
aatggcaaagacagcctaaccatgccagggtcccgggcctccacggcttctgcttctgcc
gcagtctctgcggcccggccccgccagcaccagaaatccatgtcggcctccgtgcacccc
aacaaggcctctgggctgccccccacggagagtaactgtgaggtgccgcggcccagcaca
gccccccagcgtgtccctgttgcctccccatccgcccacaacatcagcagcagtggtgga
gccccagaccgaactaacttcccccggggtgtgtccagccgaagcaccttccatgctggg
cagctccgacaggtgcgggaccagcagaatttgccctacggtgtgaccccagcctctccc
tctggccacagccagggccggcggggggcctctgggagcatcttcagcaagttcacctcc
aagtttgtacgcagaaatctgtctttcaggtttgccagaaggaacctgaatgaacctgaa
agcaaagaccgagtggagacgctcagacctcacgtggtgggcagtggcggcaacgacaaa
gaaaaggaagaatttcgggaggccaagccccgctccctccgcttcacgtggagtatgaag
accacgagctccatggagcccaacgagatgatgcgggagatccgcaaggtgctggacgcg
aacagctgccagagcgagctgcatgagaagtacatgctgctgtgcatgcacggcacgccg
ggccacgaggacttcgtgcagtgggagatggaggtgtgcaaactgccgcggctctctctc
aacggggttcgatttaagcggatatcgggcacctccatggccttcaaaaacattgcctcc
aaaatagccaacgagctgaagctttaa
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