Homo sapiens (human): 2023 Help Entry 2023              CDS       T01001                                  Gene name ENO1, ENO1L1, HEL-S-17, MPB1, NNE, PPH Definition (RefSeq) enolase 1   KO K01689   enolase [EC:4.2.1.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01230   Biosynthesis of amino acids hsa03018   RNA degradation hsa04066   HIF-1 signaling pathway Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00002   Glycolysis, core module involving three-carbon compounds hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Network nt06017  Glycogen metabolism   Element N00731   Glycolysis N00733   LDHA deficiency in glycolysis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     2023 (ENO1)  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03018 RNA degradation     2023 (ENO1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     2023 (ENO1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hsa03019]     2023 (ENO1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2023 (ENO1) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.1  Hydro-lyases     4.2.1.11  phosphopyruvate hydratase      2023 (ENO1) Messenger RNA biogenesis [BR:hsa03019]  Prokaryotic type   Bacterial mRNA degradation factors    RNA degradosome components     Other RNA degradosome components      2023 (ENO1) Exosome [BR:hsa04147]  Exosomal proteins   Proteins found in most exosomes    2023 (ENO1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Enolase_C Enolase_N MR_MLE_C MAAL_C Motif Other DBs NCBI-GeneID:  2023 NCBI-ProteinID:  NP_001419 OMIM:  172430 HGNC:  3350 Ensembl:  ENSG00000074800 Vega:  OTTHUMG00000001773 Pharos:  P06733(Tchem) UniProt:  P06733 A0A024R4F1 LinkDB All DBs Structure PDB:  3B97 2PSN Thumbnails Position 1p36.23 AA seq 434 aa AA seqDB search MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK GVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK AGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFRE AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKV VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD WGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLA QANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSK AKFAGRNFRNPLAK NT seq 1305 nt NT seq  +upstreamnt  +downstreamnt atgtctattctcaagatccatgccagggagatctttgactctcgcgggaatcccactgtt gaggttgatctcttcacctcaaaaggtctcttcagagctgctgtgcccagtggtgcttca actggtatctatgaggccctagagctccgggacaatgataagactcgctatatggggaag ggtgtctcaaaggctgttgagcacatcaataaaactattgcgcctgccctggttagcaag aaactgaacgtcacagaacaagagaagattgacaaactgatgatcgagatggatggaaca gaaaataaatctaagtttggtgcgaacgccattctgggggtgtcccttgccgtctgcaaa gctggtgccgttgagaagggggtccccctgtaccgccacatcgctgacttggctggcaac tctgaagtcatcctgccagtcccggcgttcaatgtcatcaatggcggttctcatgctggc aacaagctggccatgcaggagttcatgatcctcccagtcggtgcagcaaacttcagggaa gccatgcgcattggagcagaggtttaccacaacctgaagaatgtcatcaaggagaaatat gggaaagatgccaccaatgtgggggatgaaggcgggtttgctcccaacatcctggagaat aaagaaggcctggagctgctgaagactgctattgggaaagctggctacactgataaggtg gtcatcggcatggacgtagcggcctccgagttcttcaggtctgggaagtatgacctggac ttcaagtctcccgatgaccccagcaggtacatctcgcctgaccagctggctgacctgtac aagtccttcatcaaggactacccagtggtgtctatcgaagatccctttgaccaggatgac tggggagcttggcagaagttcacagccagtgcaggaatccaggtagtgggggatgatctc acagtgaccaacccaaagaggatcgccaaggccgtgaacgagaagtcctgcaactgcctc ctgctcaaagtcaaccagattggctccgtgaccgagtctcttcaggcgtgcaagctggcc caggccaatggttggggcgtcatggtgtctcatcgttcgggggagactgaagataccttc atcgctgacctggttgtggggctgtgcactgggcagatcaagactggtgccccttgccga tctgagcgcttggccaagtacaaccagctcctcagaattgaagaggagctgggcagcaag gctaagtttgccggcaggaacttcagaaaccccttggccaagtaa

Homo sapiens (human): 2026 Help Entry 2026              CDS       T01001                                  Gene name ENO2, HEL-S-279, NSE Definition (RefSeq) enolase 2   KO K01689   enolase [EC:4.2.1.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01230   Biosynthesis of amino acids hsa03018   RNA degradation hsa04066   HIF-1 signaling pathway Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00002   Glycolysis, core module involving three-carbon compounds hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Network nt06017  Glycogen metabolism   Element N00731   Glycolysis N00733   LDHA deficiency in glycolysis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     2026 (ENO2)  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03018 RNA degradation     2026 (ENO2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     2026 (ENO2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hsa03019]     2026 (ENO2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2026 (ENO2) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.1  Hydro-lyases     4.2.1.11  phosphopyruvate hydratase      2026 (ENO2) Messenger RNA biogenesis [BR:hsa03019]  Prokaryotic type   Bacterial mRNA degradation factors    RNA degradosome components     Other RNA degradosome components      2026 (ENO2) Exosome [BR:hsa04147]  Exosomal proteins   Proteins found in most exosomes    2026 (ENO2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Enolase_C Enolase_N MR_MLE_C MAAL_C Motif Other DBs NCBI-GeneID:  2026 NCBI-ProteinID:  NP_001966 OMIM:  131360 HGNC:  3353 Ensembl:  ENSG00000111674 Vega:  OTTHUMG00000168967 Pharos:  P09104(Tbio) UniProt:  P09104 Q6FHV6 LinkDB All DBs Structure PDB:  2AKZ 3UJR 3UCD 3UCC 3UJE 3UJS 1TE6 2AKM 4ZCW 5EU9 3UJF 4ZA0 5TD9 5TIJ 5IDZ Thumbnails Position 12p13.31 AA seq 434 aa AA seqDB search MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE ARFAGHNFRNPSVL NT seq 1305 nt NT seq  +upstreamnt  +downstreamnt atgtccatagagaagatctgggcccgggagatcctggactcccgcgggaaccccacagtg gaggtggatctctatactgccaaaggtcttttccgggctgcagtgcccagtggagcctct acgggcatctatgaggccctggagctgagggatggagacaaacagcgttacttaggcaaa ggtgtcctgaaggcagtggaccacatcaactccaccatcgcgccagccctcatcagctca ggtctctctgtggtggagcaagagaaactggacaacctgatgctggagttggatgggact gagaacaaatccaagtttggggccaatgccatcctgggtgtgtctctggccgtgtgtaag gcaggggcagctgagcgggaactgcccctgtatcgccacattgctcagctggccgggaac tcagacctcatcctgcctgtgccggccttcaacgtgatcaatggtggctctcatgctggc aacaagctggccatgcaggagttcatgatcctcccagtgggagctgagagctttcgggat gccatgcgactaggtgcagaggtctaccatacactcaagggagtcatcaaggacaaatac ggcaaggatgccaccaatgtgggggatgaaggtggctttgcccccaatatcctggagaac agtgaagccttggagctggtgaaggaagccatcgacaaggctggctacacggaaaagatc gttattggcatggatgttgctgcctcagagttttatcgtgatggcaaatatgacttggac ttcaagtctcccactgatccttcccgatacatcactggggaccagctgggggcactctac caggactttgtcagggactatcctgtggtctccattgaggacccatttgaccaggatgat tgggctgcctggtccaagttcacagccaatgtagggatccagattgtgggtgatgacctg acagtgaccaacccaaaacgtattgagcgggcagtggaagaaaaggcctgcaactgtctg ctgctcaaggtcaaccagatcggctcggtcactgaagccatccaagcgtgcaagctggcc caggagaatggctggggggtcatggtgagtcatcgctcaggagagactgaggacacattc attgctgacctggtggtggggctgtgcacaggccagatcaagactggtgccccgtgccgt tctgaacgtctggctaaatacaaccagctcatgagaattgaggaagagctgggggatgaa gctcgctttgccggacataacttccgtaatcccagtgtgctgtga

Homo sapiens (human): 2027 Help Entry 2027              CDS       T01001                                  Gene name ENO3, GSD13, MSE Definition (RefSeq) enolase 3   KO K01689   enolase [EC:4.2.1.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01230   Biosynthesis of amino acids hsa03018   RNA degradation hsa04066   HIF-1 signaling pathway Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00002   Glycolysis, core module involving three-carbon compounds hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Network nt06017  Glycogen metabolism   Element N00731   Glycolysis N00733   LDHA deficiency in glycolysis N00735   ENO3 deficiency in glycolysis Disease H00069   Glycogen storage disease H01762   Muscle glycogen storage disease H01953   Glycogen storage disease type XIII Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     2027 (ENO3)  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03018 RNA degradation     2027 (ENO3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     2027 (ENO3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hsa03019]     2027 (ENO3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2027 (ENO3) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.1  Hydro-lyases     4.2.1.11  phosphopyruvate hydratase      2027 (ENO3) Messenger RNA biogenesis [BR:hsa03019]  Prokaryotic type   Bacterial mRNA degradation factors    RNA degradosome components     Other RNA degradosome components      2027 (ENO3) Exosome [BR:hsa04147]  Exosomal proteins   Proteins found in most exosomes    2027 (ENO3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Enolase_C Enolase_N MR_MLE_C MAAL_C Motif Other DBs NCBI-GeneID:  2027 NCBI-ProteinID:  NP_001967 OMIM:  131370 HGNC:  3354 Ensembl:  ENSG00000108515 Vega:  OTTHUMG00000099394 Pharos:  P13929(Tbio) UniProt:  P13929 LinkDB All DBs Structure PDB:  2XSX Thumbnails Position 17p13.2 AA seq 434 aa AA seqDB search MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK AIFAGRKFRNPKAK NT seq 1305 nt NT seq  +upstreamnt  +downstreamnt atggccatgcagaaaatctttgcccgggaaatcttggactccaggggcaaccccacggtg gaggtggacctgcacacggccaagggccgattccgagcagctgtgcccagtggggcttcc acgggtatctatgaggctctggaactaagagacggagacaaaggccgctacctggggaaa ggagtcctgaaggctgtggagaacatcaacaatactctgggccctgctctgctgcaaaag aaactaagcgttgtggatcaagaaaaagttgacaaatttatgattgagctagatgggacc gagaataagtccaagtttggggccaatgccatcctgggcgtgtccttggccgtgtgtaag gcgggagcagctgagaagggggtccccctgtaccgccacatcgcagatctcgctgggaac cctgacctcatactcccagtgccagccttcaatgtgatcaacgggggctcccatgctgga aacaagctggccatgcaggagttcatgattctgcctgtgggagccagctccttcaaggaa gccatgcgcattggcgccgaggtctaccaccacctcaagggggtcatcaaggccaagtat gggaaggatgccaccaatgtgggtgatgaaggtggcttcgcacccaacatcctggagaac aatgaggccctggagctgctgaagacggccatccaggcggctggttacccagacaaggtg gtgatcggcatggatgtggcagcatctgagttctatcgcaatgggaagtacgatcttgac ttcaagtcgcctgatgatcccgcacggcacatcactggggagaagctcggagagctgtat aagagctttatcaagaactatcctgtggtctccatcgaagacccctttgaccaggatgac tgggccacttggacctccttcctctcgggggtgaacatccagattgtgggggatgacttg acagtcaccaaccccaagaggattgcccaggccgttgagaagaaggcctgcaactgtctg ctgctgaaggtcaaccagatcggctcggtgaccgaatcgatccaggcgtgcaaactggct cagtctaatggctggggggtgatggtgagccaccgctctggggagactgaggacacattc attgctgaccttgtggtggggctctgcacaggacagatcaagactggcgccccctgccgc tcggagcgtctggccaaatacaaccaactcatgaggatcgaggaggctcttggggacaag gcaatctttgctggacgcaagttccgtaacccgaaggccaagtga

Homo sapiens (human): 387712 Help Entry 387712            CDS       T01001                                  Gene name ENO4, C10orf134 Definition (RefSeq) enolase 4   KO K01689   enolase [EC:4.2.1.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa01230   Biosynthesis of amino acids hsa03018   RNA degradation hsa04066   HIF-1 signaling pathway Module hsa_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate hsa_M00002   Glycolysis, core module involving three-carbon compounds hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Network nt06017  Glycogen metabolism   Element N00731   Glycolysis N00733   LDHA deficiency in glycolysis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     387712 (ENO4)  09120 Genetic Information Processing   09123 Folding, sorting and degradation    03018 RNA degradation     387712 (ENO4)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     387712 (ENO4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:hsa03019]     387712 (ENO4)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     387712 (ENO4) Enzymes [BR:hsa01000]  4. Lyases   4.2  Carbon-oxygen lyases    4.2.1  Hydro-lyases     4.2.1.11  phosphopyruvate hydratase      387712 (ENO4) Messenger RNA biogenesis [BR:hsa03019]  Prokaryotic type   Bacterial mRNA degradation factors    RNA degradosome components     Other RNA degradosome components      387712 (ENO4) Exosome [BR:hsa04147]  Exosomal proteins   Proteins found in most exosomes    387712 (ENO4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Enolase_C Enolase_N Porin_2 PRIMA1 Motif Other DBs NCBI-GeneID:  387712 NCBI-ProteinID:  NP_001229628 OMIM:  131375 HGNC:  31670 Ensembl:  ENSG00000188316 UniProt:  A6NNW6 LinkDB All DBs Position 10q25.3 AA seq 625 aa AA seqDB search MEEEGGGRSCGTTRELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFS KLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALPELA KAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEK SLEYSTVPTPLPPVPPPPPPPPPTKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGA VSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEV ICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLG CLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMGTYKNA AEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQ GNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLG VRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAA AREPLVPTFPTQGVEESAETGASSG NT seq 1878 nt NT seq  +upstreamnt  +downstreamnt atggaggaagaaggcggcggccgcagctgtgggaccactagggagctgcagaagctgaag cagcaggcgatggagtactaccgggagaacgacgttccgcgcaggctggaagagctgctc aactccaccttctacctccagcctgccgacgtctacgggcacctggcaaactgcttttct aaacttgcaaagcctcccaccatatgcaaaatagtggggaaagacgtactagatggactg gggcttccaaccctgcaagtggacatattctgcaccattcaaaactttcccaagaacgta tgttctgtggtgatctcgactcattttgaagtccatgagaatgctctgcccgagctggcc aaggcggaggaggcagagagggccagcgcggtgagcaccgccgtgcagtgggtcaacagc accatcacgcacgagctccaggggatggcaccctctgaccaggcagaggtggatcaccta ctcaggatattcttcgcaagtaaagtacaagaagataaggggagaaaagaattggaaaag agcctggaatactcaacagtgcctacacctctacctccagtaccaccaccaccaccccct ccacctcctaccaaaaaaaaggggcaaaagccagggaggaaggatactattacagagaaa cctattgcgcctgcagagcctgttgagcctgtactcagtggcagtatggccataggggcc gtgtcactagctgttgccaaagcctgtgccatgctgcttaataaacctctgtacttaaat atcgctctactgaagcacaatcaggaacagccaacaacgctatctatgcctttgctgatg gtatcgctggtcagctgtgggaagtcatcatctgggaagctaaatttaatgaaagaagtg atttgtataccccatcctgaattaacaaccaaacaaggtgtcgagatgcttatggaaatg cagaaacatatcaacaaaataattgaaatgccctctcctccaaaagcagagacaaaaaaa gggcacgatggaagcaaaagaggtcaacagcagatcactggcaagatgtctcatcttggc tgtttaaccattaactgtgactccatagaacagccactgcttctaatacaggaaatctgt gccaacctggggctagaactgggaacaaatctgcatctagctatcaactgtgctggacat gagctgatggactacaataaaggaaagtatgaagtgatcatgggcacatacaaaaatgca gcggagatggttgacctgtatgtggatctgatcaacaagtacccttcaattattgcctta attgatcctttcaggaaggaggactctgaacagtgggacagcatctatcacgcacttggt tccaggtgttacataattgcaggaactgcttccaaaagcatttctaaacttctagagcaa ggaaacatcagcatccccaaatccaatgggctgatcataaaacacacaaaccaaactaca atgtctgacttggtggaaataaccaatctgattgacagtaagaagcacatcactgtcttt ggaagtacagaaggagaatcatctgatgacagccttgtcgatttggctgttgggcttggt gtccggttcatcaagttggggggtctttcccgtggtgaacgagtgactaaatacaaccgc cttctcactatagaggaagaacttgtccagaatggaacactgggtttcaaagaagaacac acttttttttactttaatgaggaagctgaaaaggctgcggaggcacttgaggctgctgcg gctagggagccgctggtgcccaccttccccacacaaggtgtagaggaatcagccgaaaca ggagcatcctctggatag

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