Homo sapiens (human): 2203 Help Entry 2203              CDS       T01001                                  Symbol FBP1, FBP Name (RefSeq) fructose-bisphosphatase 1   KO K03841   fructose-1,6-bisphosphatase I [EC:3.1.3.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa00030   Pentose phosphate pathway hsa00051   Fructose and mannose metabolism hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa04152   AMPK signaling pathway hsa04910   Insulin signaling pathway hsa04922   Glucagon signaling pathway Module hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Disease H00114   Fructose-1,6-bisphosphatase deficiency Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     2203 (FBP1)    00030 Pentose phosphate pathway     2203 (FBP1)    00051 Fructose and mannose metabolism     2203 (FBP1)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     2203 (FBP1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     2203 (FBP1)    04922 Glucagon signaling pathway     2203 (FBP1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2203 (FBP1) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.3  Phosphoric-monoester hydrolases     3.1.3.11  fructose-bisphosphatase      2203 (FBP1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    2203 (FBP1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FBPase FBPase_C Inositol_P Motif Other DBs NCBI-GeneID:  2203 NCBI-ProteinID:  NP_000498 OMIM:  611570 HGNC:  3606 Ensembl:  ENSG00000165140 Vega:  OTTHUMG00000020268 Pharos:  P09467(Tchem) UniProt:  P09467 LinkDB All DBs Structure PDB:  5PZU 5Q09 5PZR 5PZW 5PZV 2JJK 5ZWK 5Q02 2Y5K 5Q05 5Q08 5LDZ 2Y5L 5PZY 2WBB 3KC1 5Q0B 5Q0A 1FTA 5Q03 5PZS 5Q06 4MJO 2WBD 5Q07 3KBZ 5PZZ 5Q04 5Q00 5Q01 3A29 5PZQ 5PZX 5PZT 3KC0 2FIE 2FHY 2FIX 2VT5 Thumbnails Position 9q22.32 AA seq 338 aa AA seqDB search MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGI AGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDP LDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDC GVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAP YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGK EAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt atggctgaccaggcgcccttcgacacggacgtcaacaccctgacccgcttcgtcatggag gagggcaggaaggcccgcggcacgggcgagttgacccagctgctcaactcgctctgcaca gcagtcaaagccatctcttcggcggtgcgcaaggcgggcatcgcgcacctctatggcatt gctggttctaccaacgtgacaggtgatcaagttaagaagctggacgtcctctccaacgac ctggttatgaacatgttaaagtcatcctttgccacgtgtgttctcgtgtcagaagaagat aaacacgccatcatagtggaaccggagaaaaggggtaaatatgtggtctgttttgatccc cttgatggatcttccaacatcgattgccttgtgtccgttggaaccatttttggcatctat agaaagaaatcaactgatgagccttctgagaaggatgctctgcaaccaggccggaacctg gtggcagccggctacgcactgtatggcagtgccaccatgctggtccttgccatggactgt ggggtcaactgcttcatgctggacccggccatcggggagttcattttggtggacaaggat gtgaagataaaaaagaaaggtaaaatctacagccttaacgagggctacgccagggacttt gaccctgccgtcactgagtacatccagaggaagaagttccccccagataattcagctcct tatggggcccggtatgtgggctccatggtggctgatgttcatcgcactctggtctacgga gggatatttctgtaccccgctaacaagaagagccccaatggaaagctgagactgctgtac gaatgcaaccccatggcctacgtcatggagaaggctgggggaatggccaccactgggaag gaggccgtgttagacgtcattcccacagacattcaccagagggcgccggtgatcttggga tcccccgacgacgtgctcgagttcctgaaggtgtatgagaagcactctgcccagtga

Homo sapiens (human): 8789 Help Entry 8789              CDS       T01001                                  Symbol FBP2 Name (RefSeq) fructose-bisphosphatase 2   KO K03841   fructose-1,6-bisphosphatase I [EC:3.1.3.11] Organism hsa  Homo sapiens (human) Pathway hsa00010   Glycolysis / Gluconeogenesis hsa00030   Pentose phosphate pathway hsa00051   Fructose and mannose metabolism hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa04152   AMPK signaling pathway hsa04910   Insulin signaling pathway hsa04922   Glucagon signaling pathway Module hsa_M00003   Gluconeogenesis, oxaloacetate => fructose-6P Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     8789 (FBP2)    00030 Pentose phosphate pathway     8789 (FBP2)    00051 Fructose and mannose metabolism     8789 (FBP2)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     8789 (FBP2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     8789 (FBP2)    04922 Glucagon signaling pathway     8789 (FBP2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     8789 (FBP2) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.3  Phosphoric-monoester hydrolases     3.1.3.11  fructose-bisphosphatase      8789 (FBP2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    8789 (FBP2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FBPase FBPase_C Inositol_P ABC2_membrane Motif Other DBs NCBI-GeneID:  8789 NCBI-ProteinID:  NP_003828 OMIM:  603027 HGNC:  3607 Ensembl:  ENSG00000130957 Vega:  OTTHUMG00000020269 Pharos:  O00757(Tbio) UniProt:  O00757 LinkDB All DBs Structure PDB:  4HE2 5ET5 5K54 5ET6 5ET8 3IFA 3IFC 5K55 5K56 4HE1 5L0A 5Q0C 4HE0 5ET7 Thumbnails Position 9q22.32 AA seq 339 aa AA seqDB search MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGI AGSVNVTGDEVKKLDVLSNSLVINMVQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDP LDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQ GVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAP YGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGS NT seq 1020 nt NT seq  +upstreamnt  +downstreamnt atgacggacagaagccccttcgaaaccgacatgctcaccctgacccgctacgttatggaa aaggggcgtcaggccaaagggactggggagctcacccagctgctgaactcaatgctgacg gccatcaaagccatctcctcggctgtgcgcaaggccggtctggcccacctgtatggaatc gcaggaagcgttaacgtgacgggagatgaggtgaagaaactggatgtgctatccaattcc ctggtgatcaacatggtccaatcctcctatagtacctgcgtcctggtctcagaagagaat aaggacgccatcatcaccgccaaggagaagcgggggaaatacgtggtctgctttgaccca ctggatggatcttccaatattgactgcctggcctccatcggaaccatctttgccatctat agaaagacctcagaggatgagccttctgaaaaggatgccctgcagtgtggccgcaatatt gtggccgcaggttatgcgctgtacggtagtgcaaccctggtggctctctccacagggcaa ggcgtggacctcttcatgcttgacccggctcttggtgaatttgtcctggtggaaaaagat gtcaagattaagaagaaaggaaagatttacagcctgaatgagggctatgccaagtatttt gatgcggccaccactgaatatgtgcagaaaaagaaattccctgaggatggcagtgctccc tatggggccaggtatgtgggctccatggtggctgacgtgcaccgcaccctggtctatgga ggaatcttcctgtacccagccaaccagaagagccctaagggcaagctccggctcctgtat gaatgcaatcccgtggcctacatcattgagcaggcaggaggcttggcgaccacggggacc cagcctgtactggacgtgaagcccgaggcaattcaccagcgagtccccctcattctgggg tcaccagaggatgtgcaggaatatctcacctgtgtgcagaaaaatcaggcaggcagctag

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