Homo sapiens (human): 221037
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Entry
221037 CDS
T01001
Symbol
JMJD1C, KDM3C, TRIP-8, TRIP8
Name
(RefSeq) jumonji domain containing 1C
KO
K11449
jumonji domain-containing protein 1C [EC:1.14.11.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05202
Transcriptional misregulation in cancer
Network
nt06240
Transcription (cancer)
Element
N00119
MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
221037 (JMJD1C)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
221037 (JMJD1C)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
Histone demethylases
221037 (JMJD1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tudor_KDM3B
PWWP_KDM3B
DUF7030
JmjC
C1_2
zf-C5HC2
FYVE
Motif
Other DBs
NCBI-GeneID:
221037
NCBI-ProteinID:
NP_116165
OMIM:
604503
HGNC:
12313
Ensembl:
ENSG00000171988
UniProt:
Q15652
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:complement(63167225..63521890)
Genome browser
AA seq
2540 aa
AA seq
DB search
MAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVE
FDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERN
IPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQE
IFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQM
TFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNT
HQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEK
KLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNE
KAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLP
QECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPN
VSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYI
SPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKA
TYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKNEHFTVYRDPALI
GSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTH
PLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQ
SPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNS
PSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELER
KAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKE
EHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDMDVERSVSDLYKM
KHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFI
TSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSM
PALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDS
QANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPA
MQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSV
PSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQ
PVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS
ETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSE
EDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKR
TYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKE
RSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSK
KGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIE
TSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVC
QKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAM
HTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISLCMPESQQQNTPP
KSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEER
EQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSK
SGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHS
WICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQA
DLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYED
LLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVS
DVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVD
KIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVL
PAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILYHAV
KEMVRALKIHEDEVEDMEEN
NT seq
7623 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagagacgcgggcagagctggtgggtaagcggttcctgtgtgtggcggtcggc
gacgaggcacgttcggagcgctgggagagcggacgcggctggcgaagctggcgagcgggg
gtcatccgagccgtgtcacacagggacagccgcaatccggacctggcggtgtatgtggaa
tttgatgatcttgaatgggataaacgagagtgggttaaagtttatgaagatttttcaact
ttcttggtggaataccacttaatctgggccaaaaggaatgaccctagccagactcaggga
tcaaagagcaaacagattcagtggcctgcattgactttcaaacctctggttgaaagaaat
atacccagttcagtcactgcagtagaattccttgtagataagcaactggattttttaact
gaagatagtgcctttcagccctaccaggacgacatagacagcctaaacccagttctcagg
gacaacccgcagcttcatgaggaagtgaaagtctgggtaaaggaacaaaaggttcaggag
atttttatgcaaggtccttattccttaaatggatacagagtgagagtatatagacaagac
tctgccacccagtggtttactggcataattactcatcatgatctcttcacccgcaccatg
atcgttatgaatgatcaggtactagaaccacagaatgtcgatccttctatggttcaaatg
acctttctagatgatgttgttcactctttgttaaaaggtgaaaatattggcattacatca
cgacgcaggtctcgtgccaatcaaaacgtcaacgctgttcacagccattatacacgtgcc
caagcaaatagtcccagaccagcaatgaactcccaagctgctgtaccaaaacagaataca
caccagcaacagcaacaaagaagtatccgtccaaataagaggaagggctcagatagcagt
ataccagatgaagagaagatgaaggaggaaaaatatgattatatatcacgaggagaaaat
cctaaaggtaaaaacaaacacttgatgaataaaagaaggaaacctgaggaggatgaaaag
aaactaaatatgaaaagacttcgaactgacaatgtttcagacttttctgagagcagtgac
tcagaaaattcaaataagagaataatagataattcctcagaacagaagccagagaatgaa
ttgaaaaataaaaatacttcaaaaataaatggagaagaaggaaaaccccataataatgag
aaggcaggagaagagaccctaaaaaatagccagcctccctgggatcaaatacaggaagat
aaaaaacatgaagaagcagagaagcggaagtctgttgacactcagcttcaagaagatatg
attattcattcgtcagaacagtccacagtttctgatcataattctaatgatttacttcct
caggaatgcaatatggataaaacacataccatggaattgctaccaaaggagaagtttgta
tccagaccacccacaccaaaatgtgttattgatattacaaatgacactaatttagaaaag
gtggctcaggaaaactcaagtacctttggccttcagacacttcagaaaatggatcctaat
gttagtgattcaaaacactctattgcaaatgcaaaattcttggaaacagcaaaaaaagat
tctgaccagagctgggtcagtgatgtagttaaagtggatctaacccaatcaagtgttaca
aatgcttcttcaggaaatgatcacttgaacatggaaaaagagaagtatgtctcttacatt
tctcctttaagtgcagtttctgtcatggaagataagctgcataagcgaagtccacctcca
gagactataaaatctaaacttaatacttcagtagatactcacaagataaaatccagccca
tcacctgaagttgttaaacccaaaataactcattctcctgattctgtaaagtctaaggcc
acttatgtgaacagccaagctactggtgaaagaagattggcaaataagatagaacatgag
ctatcaagatgcagttttcatccaattcctactcgaagcagtacattagaaactacaaag
agtcctcttatcattgataaaaatgagcattttacagtttacagagatcctgcacttatt
gggtcagaaacaggagctaatcatatttcacctttcctaagccagcatccttttcctctt
cactcctcatctcatagaacctgtttaaatccaggtacccatcatcctgccttaactcct
gcaccccatttactagccggatcatctagtcaaactccattacctaccattaacactcat
cctctgactagtggtccacaccatgctgttcatcaccctcatttacttcccactgtgtta
cctggagtgcctactgcctccttacttggtggccacccacgactagagagtgctcatgcc
agcagcttgagccacttagcgctagcacaccagcaacaacaacagttgttacagcaccag
tcacctcatcttcttggacaagcccatccttctgcttcatataatcagcttggactttat
ccaattatttggcagtatccaaatggaacacatgcatactcaggacttggtttgccttct
tctaagtgggttcacccagaaaatgcagttaatgctgaagcttcattaaggaggaattct
cccagtccttggctacatcagcccacccctgtgacctcagcagatggtattggattactt
agtcacattcctgtcagaccttccagtgcagagcctcatcggcctcttaaaattacagcc
cattccagtccaccattgacaaaaactttagtagatcatcataaggaagaattagaaaga
aaagcttttatggaaccattacggtctgttgcatccacatcagccaaaaatgacctggat
ctaaataggtcacagactggaaaagattgtcacttacataggcattttgtggatccagta
ttaaatcagttacagaggccaccccaggagactggagagaggttaaacaaatacaaagag
gaacaccgtcgaattcttcaagaaagtattgatgttgctccctttacaactaaaatcaag
ggacttgagggtgagagagagaattattccagagtggcatcatcatcttccagtcctaaa
agccatatcatcaaacaagatatggatgtagaacgctcagtatcagatctttataaaatg
aagcactcagtgcctcagagtttaccccaaagtaactatttcactacattgtctaatagt
gtggtcaatgaaccaccaagatcatacccatccaaagaagtttcaaatatttacggtgat
aaacagagtaatgcccttgcagcggcagcagctaatcctcaaactctgacttcatttata
acatctctttcaaagcctccacctttgattaaacaccaaccagaaagtgaaggtttagta
ggcaagataccagaacatcttccacatcagattgcatctcactcagtaacaaccttcaga
aatgattgtaggagtcctacccatttgacagtttcttctacaaatacactccgcagtatg
cctgcattacatagagcaccagtatttcacccaccaatccatcacagcctggaaagaaag
gaaggcagctatagtagtctttcccctccaactttaactccggtgatgccagtaaatgct
ggtggtaaagttcaagaatcacagaagcctccaactctaatacccgaaccaaaagactcc
caggcaaattttaagagttcttcagaacagagtttgacggagatgtggagacctaataat
aacctcagcaaagagaaaactgaatggcatgtggagaaaagcagcggaaagttacaggct
gctatggcatctgtcattgtgcgtccatcttctagtacaaaaactgatagtatgccagca
atgcagttagcttctaaagatcgtgttagtgaaagatcttcagctggggcacataaaaca
gattgcctcaaactagcagaagccggagaaactggaagaatcattttgccaaatgtgaat
tcagacagtgttcacacaaaatctgaaaaaaactttcaggctgtctcacagggcagtgtt
cccagttcagtcatgtctgctgtaaatacgatgtgtaataccaaaacggatgtaatcaca
tctgctgccgatactaccagtgtttccagctggggtggttcagaagtaatttcctcttta
tcaaataccattttggcctctacatcatcagaatgtgtatcttcaaaaagtgtcagtcag
ccagtggctcaaaaacaagaatgcaaggtcagcaccacagcaccagttacattagccagt
agtaagacaggaagtgttgttcaacccagttctgggttctcaggcacaactgattttatc
catttaaaaaagcacaaggcagcattggctgcagctcagtataaaagtagtaatgccagt
gagactgaacctaatgctataaaaaatcagacactttcagcctcccttcctctggatagc
actgtaatctgtagtacaattaacaaagcaaactctgtaggaaatgggcaagcttcccag
acaagtcaaccaaactaccatactaaactgaaaaaggcctggctcaccagacactcagaa
gaagataaaaatactaataaaatggaaaattcagggaattctgtatcagaaattattaag
ccatgttctgtcaacttaatagcctctacatctagtgatatacaaaatagtgtagatagt
aagatcatagttgataaatatgtaaaagatgataaagtcaacaggagaaaagccaaaaga
acttatgaatctggctctgaaagtggagactcagatgaaagtgaaagcaagtcagagcaa
aggactaaaagacaacctaagccaacttacaaaaagaagcaaaatgatttgcaaaagaga
aaaggtgaaatagaagaagatttgaaacccaatggagttctcagcaggagtgccaaagaa
agaagtaaactgaagttgcaaagcaacagtaatactggcattcctcgttcagtattgaaa
gattggcgtaaagtcaagaagctgaagcaaactggggaatcctttttacaggatgactcc
tgctgtgagatagggcctaatttacaaaagtgtcgagaatgtagacttattcgcagtaaa
aaaggagaagaaccagctcactcaccagtattttgtagattttactactttagacggttg
tcatttagtaaaaacggagtagttagaatagatggtttctcttctcctgaccaatatgat
gatgaagctatgagtttgtggacacatgaaaattttgaagatgatgaactagatatagag
acttctaaatatatcttggatataataggtgataagttctgtcaattagtaacatctgaa
aaaacagctttgtcctgggtgaaaaaggatgccaaaattgcctggaaaagagcagtgaga
ggagtccgggagatgtgtgatgcatgtgaagcaacattgtttaacattcactgggtctgc
caaaaatgtggatttgtggtctgcttagattgttacaaggcaaaggaaaggaagagttct
agagataaagaactatatgcttggatgaagtgtgtgaagggacagcctcatgatcacaaa
catttaatgccaacccaaattatacctggttctgttttgacagatcttctagatgccatg
cacactcttagggaaaaatatggtattaaatcccattgtcattgtactaacaaacagaat
ttacaagttggaaattttcctacaatgaatggtgtatctcaagttttacagaatgttctt
aatcacagtaataaaatttctctgtgcatgcctgagtctcagcagcaaaatactcctccg
aagtctgagaaaaatggtggcagcagcccagagagtgatgtaggcacagataacaagtta
actcctccagaatcccagtcaccactgcactggttagcagatcttgcagagcaaaaagcc
agagaggaaaaaaaagaaaacaaagaacttacccttgaaaaccaaattaaagaagaaaga
gaacaagacaactctgaatctccaaatggcagaacatcacctcttgtgtcccagaataat
gaacaaggctcaaccttacgggatttgctgactacaacagctggaaagctacgtgtgggg
tctacagatgctggcattgcctttgccccagtatattcaatgggagccccaagtagcaaa
agtggacggactatgcctaacattcttgatgacataattgcttcagttgttgaaaacaaa
attccaccaagtaaaacctccaagataaatgtaaaaccagagcttaaagaagagcctgaa
gaaagcataatatctgcagtggatgaaaataataaattatacagtgatataccacattct
tggatctgtgagaagcatattttatggcttaaggattataagaatagcagtaattggaag
cttttcaaagaatgttggaaacaaggacagcctgcagtggtttctggtgtgcataagaaa
atgaacattagcctatggaaggcggaatcaattagtcttgattttggagaccaccaagct
gatctcctgaactgcaaagatagcatcatttcaaatgccaatgttaaggaattctgggat
ggttttgaagaagtttcaaaacggcagaaaaacaagagtggagaaacagttgttttaaaa
ttgaaagactggccttcaggagaagacttcaagactatgatgccagcaagatacgaagat
cttttaaaaagtctgccattgccagaatattgtaatccagaaggaaaattcaatttggcc
tctcatttgccaggattttttgtacgtcctgatctaggacccaggttgtgcagtgcctat
ggtgtagttgctgctaaagatcatgatataggaacaacaaatctccatattgaagtttct
gatgttgtaaatatactagtttatgttggcatagcaaaaggaaatggcattctctcaaaa
gcaggaattctcaagaaatttgaggaagaagatttggatgacattttaaggaaaagattg
aaggactcaagtgaaatacctggtgctctgtggcatatttatgctgggaaagatgttgac
aagataagggaatttcttcaaaagatttcaaaagaacaaggccttgaagttctaccagaa
catgatccaatacgtgaccaaagttggtatgtgaacaaaaagctccgtcaaaggctgctt
gaagaatatggagtcagaacctgtactcttattcagttccttggtgatgctattgttttg
ccagcgggagcacttcatcaggttcagaattttcacagctgtattcaggtaactgaagat
tttgtgtctccagaacatcttgtagagtcatttcatttaacacaggaactgagacttttg
aaggaagaaatcaattatgatgataaactacaggttaaaaatattttgtatcatgcagtc
aaagaaatggtgagagccttgaagatacacgaggatgaagtagaggatatggaagaaaat
taa
DBGET
integrated database retrieval system
