Homo sapiens (human): 22983
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Entry
22983 CDS
T01001
Symbol
MAST1, MCCCHCM, SAST
Name
(RefSeq) microtubule associated serine/threonine kinase 1
KO
K08789
MAST-subfamily protein kinase [EC:
2.7.11.37
]
Organism
hsa
Homo sapiens (human)
Disease
H02519
Mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
22983 (MAST1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.37 MAST-subfamily protein kinase
22983 (MAST1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
MAST family [OT]
22983 (MAST1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF1908
Pkinase
PK_Tyr_Ser-Thr
PDZ_6
PDZ
PDZ_2
ABC1
Kinase-like
APH
PDZ_Tricorn
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
22983
NCBI-ProteinID:
NP_055790
OMIM:
612256
HGNC:
19034
Ensembl:
ENSG00000105613
UniProt:
Q9Y2H9
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:12838515..12874952
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AA seq
1570 aa
AA seq
DB search
MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSS
PLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQ
LPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNH
VYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLI
TTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFY
HLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLEEQDSGGSNTPEQDDLSEG
RSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAF
VERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAE
TVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAR
EFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVI
SDDILWPEGDEALPTEAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKA
EFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQ
LSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASE
ASFLEGEASPPLGARRRFSALLEPSRFSAPQEDEDEARLRRPPRPSSDPAGSLDARAPKE
ETQGEGTSSAGDSEATDRPRPGDLCPPSKDGDASGPRATNDLVLRRARHQQMSGDVAVEK
RPSRTGGKVIKSASATALSVMIPAVDPHGSSPLASPMSPRSLSSNPSSRDSSPSRDYSPA
VSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLI
THVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRP
SAKEGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHS
YRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAG
NIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPL
LKRVQSAEKLGASLSADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPVEGL
GAPRQVAVRRLGRQESPLSLGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGR
TLERDVGCTRHQSVQTEDGTGGMARAVAKAALSPVQEHETGRRSSSGEAGTPLVPIVVEP
ARPGAKAVVPQPLGADSKGLQEPAPLAPSVPEAPRGRERWVLEVVEERTTLSGPRSKPAS
PKLSPEPQTPSLAPAKCSAPSSAVTPVPPASLLGSGTKPQVGLTSRCPAEAVPPAGLTKK
GVSSPAPPGP
NT seq
4713 nt
NT seq
+upstream
nt +downstream
nt
atgtctgactctctctggaccgcgctttctaatttctcgatgccctccttccccggcggc
agtatgttccgccgcaccaagagctgccgcaccagtaatcggaaaagcctcatcctgacc
agcacttcacccacgctaccgagaccccactccccgctgccaggtcacctaggcagcagt
cccctggacagcccccgaaacttctcccccaacacccccgcccacttctcgtttgcctcc
tcccgaagggcggacggacgccggtggtctctggcctcgctcccttcatctggctatggc
accaacacgcccagttccaccgtctcgtcctcctgctcctcccaggagcgccttcaccag
ctgccctaccagcccacggtggacgagctccacttcctctccaaacacttcgggagcacc
gagagcatcacagacgaggatggtggccgtcgctccccagccgtgcggccccgctcacgg
agcctcagccccgggcgctccccctcctcctacgacaacgagatcgtgatgatgaatcac
gtctacaaggagaggttcccgaaggccactgcgcagatggaggagaagctgcgcgacttt
acccgcgcctacgaacccgacagcgttctgcctctggccgatggcgtgctcagcttcatc
caccaccagatcatcgagctggcccgggactgcctgaccaagtcccgtgacggcctcatc
accacggtctacttctatgaattgcaggagaacctggagaagctccttcaagacgcctat
gaacgctctgagagcttggaggtggccttcgttactcagctggtgaagaagttgcttatt
atcatctcacgccctgcgaggctgctggagtgcctggaattcaaccccgaggagttctac
cacctgctggaggcggccgaaggacacgccaaggagggccaccttgtgaagacggacatc
ccccgctacatcatccgccagctgggcctcacccgtgacccctttccagatgtggtgcat
ctggaggaacaggacagtggtggttccaacacccctgagcaagacgatctctctgagggc
cgcagcagcaaggccaagaaaccgccgggggagaatgacttcgataccatcaagctcata
agcaacggtgcctacggcgctgtctacctggtgcggcaccgcgacacgcggcagcgcttt
gccatgaaaaagatcaacaagcagaacttgatcctccgcaaccagatccagcaggccttt
gtggagcgcgatatcctcaccttcgccgagaacccgtttgtggtcggcatgttctgctcc
tttgagactcggcgccacctctgcatggtcatggaatatgtggaaggcggcgactgtgcc
accctgctgaagaatattggagcgctgcccgtagagatggcccgcatgtactttgctgag
acggtgctagccctggagtatttgcacaactatggcatcgtgcaccgcgacctcaagcct
gacaacctccttatcacctccatgggtcacatcaagctcacagatttcggcctctccaag
atggggctcatgagcctcaccaccaacttatatgaaggccacatcgagaaggacgcccga
gagttcctggacaaacaggtgtgtgggaccccagagtacatcgcgcccgaggtcatcctg
cgtcaaggctacggcaagccagtggactggtgggctatggggatcatcctctacgagttc
ctggtgggctgtgtgcccttcttcggagacacaccagaggagctatttggacaggtcatc
agtgatgacatcctgtggcccgagggggatgaggccctacctacggaggcccaactcctc
atatccagcctcctgcagaccaaccctctggtcaggcttggggcaggcggcgcttttgag
gtgaagcagcacagtttctttcgagacctggactggacagggctgctgaggcagaaggcc
gagttcatcccccacctagagtcggaagatgacactagctactttgacacccgctcagac
aggtatcaccacgtgaactcctatgacgaggatgacacgacggaggaggagcccgtggaa
atccgccagttctcttcctgctctccgcgcttcagcaaggtgtatagcagcatggagcag
ctgtcgcagcacgagcccaagaccccagtagcagctgcagggagcagcaagcgggagccg
agcaccaagggccccgaggagaaggtggccggcaagcgggaggggctgggcggcctgacc
ctgcgtgagaagacctggagagggggctctccggagatcaagcgattctccgcgtccgag
gccagtttcctggagggagaggccagtccccctttgggcgcccgccgccgtttctcggcg
ctgctggagcccagccgcttcagcgccccccaagaggacgaggatgaggcccggctgcgc
aggcctccccggcccagctccgaccccgcgggatccctggatgcacgggcccccaaagag
gagactcaaggggaaggcacctccagcgccggggactccgaggccactgaccgtccacgc
ccaggtgacctctgcccaccctcgaaggatggggatgcatcaggcccaagggctaccaat
gacttggttctgcgccgggcgcggcaccagcagatgtcaggggatgtggcagtagagaag
aggccttctcgaactgggggcaaagtcatcaaatcagcctcagccactgccttatctgtc
atgattcctgcagtggacccacatggaagttcaccccttgctagtcccatgtctccacga
tctctgtcctccaacccatcctcacgggactcctcacccagccgggactactcaccagct
gtcagtgggctccgctcccccatcaccatccagcgctcgggcaagaagtatggcttcaca
ctgcgtgccatccgtgtctacatgggtgacacggatgtctatagtgtccaccacattgtc
tggcatgtggaggaaggaggcccagcccaggaggcaggactctgtgctggggacctcatc
acccacgtgaatggggagcctgtgcatggcatggtgcatcctgaggtcgtggagctgatc
cttaagagtggcaacaaggtagcagtgaccacaacgcccttcgaaaatacctctatccgc
attggtcccgcaaggcgcagcagctacaaggctaaaatggctcggaggaacaagcgaccc
tccgccaaggagggccaggagagcaagaagcgcagctccctcttccggaagatcacgaag
cagtcgaacctgctgcatactagccgctcgctgtcgtcgctgaaccgctcgctgtcatcc
agcgatagtctcccgggctcgcctacgcacgggctgccggcgcgctcgcccacgcacagc
taccgctccacgcctgactccgcctacctaggcgcctcatcccagagcagctccccagcc
tcgagcacgcccaactcgcctgcgtcgtcggcgtcgcaccacattcggcccagcacgctg
cacggactgtcgccaaagctccatcgccagtaccgctctgcgcgatgcaagtcggccggc
aacatccctctatcgccgctggcacacacgccgtcccccacgcaggcgtcaccgccgcca
ctgccgggccacacggtgggcagctcgcacactactcagagcttcccggccaaactgcac
tcatcgcctcccgtcgtgcgcccgcgccccaagagtgccgagccccctcgctcgccgctc
ctcaagcgcgtgcagtcggccgagaagctgggagcctctttgagtgcggacaagaagggc
gcgctgcgcaaacacagcctcgaggtgggccacccggatttccgcaaggacttccatggc
gagctggcgctgcatagccttgccgagtccgacggtgagacgcccccagtcgagggcctt
ggcgcgccccggcaggtcgccgtccgccgcctgggccgacaggagtcacctttgagcctg
ggcgcggacccgttgctgcccgagggtgcctccaggccaccagtgtcgagcaaggagaag
gaatccccggggggcgccgaggcgtgcaccccaccccgcgcgacgacccccggtggccgg
accctggagcgggacgtcggctgcacgcggcatcagagcgtgcagacggaggatggcact
ggcgggatggccagggctgtggccaaggcggcgctgagcccggtgcaggaacacgagaca
ggccggcgcagcagctctggcgaggcgggcacacccctggtacccattgtcgtagagcct
gcgcggcccggggctaaggctgtggtgcctcagcctctgggcgcggactccaaggggttg
caggaacccgcacccctggcgccttccgtgcccgaggccccccggggccgggagcgctgg
gtgttggaggtggtggaggagcgcaccacgctgagcggtcctcgctccaagcccgcctcc
ccaaagctctccccggagccccagacaccctccctagccccagcgaagtgcagtgcaccc
agcagtgcagtgaccccagtcccacccgcatccctcttgggctcaggcaccaagcctcaa
gtggggctgacctcccggtgccctgctgaagctgtgcccccagcaggcctgaccaaaaaa
ggagtgtccagtcccgcacccccgggaccatag
DBGET
integrated database retrieval system
