Homo sapiens (human): 23007
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Entry
23007 CDS
T01001
Symbol
PLCH1, HPE14, PLC_eta_1, PLC-L3, PLCL3
Name
(RefSeq) phospholipase C eta 1
KO
K19006
phosphatidylinositol phospholipase C, eta [EC:
3.1.4.11
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00562
Inositol phosphate metabolism
hsa01100
Metabolic pathways
Disease
H00267
Holoprosencephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
23007 (PLCH1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
23007 (PLCH1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
23007 (PLCH1)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
23007 (PLCH1)
Endocytosis
Macropinocytosis
Phospholipase C
23007 (PLCH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
C2
EF-hand_like
EF-hand_7
EF-hand_1
PH_12
EF-hand_6
EF-hand_8
EF-hand_10
EF-hand_5
AIF-1
PH
EH
SPARC_Ca_bdg
Motif
Other DBs
NCBI-GeneID:
23007
NCBI-ProteinID:
NP_001124432
OMIM:
612835
HGNC:
29185
Ensembl:
ENSG00000114805
UniProt:
Q4KWH8
LinkDB
All DBs
Position
3:complement(155450934..155745071)
Genome browser
AA seq
1693 aa
AA seq
DB search
MADLEVYKNLSPEKVERCMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSE
KAKILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWI
TGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPR
RKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFL
KVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQD
MDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHG
YTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFGDKLDLSS
VDTGECKQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSN
GTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLNAHLKQSPDVKESG
KKSHGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRE
LSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAY
RIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGTFNP
FSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTR
VVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVY
LEGLTEASIFVHITINEIYGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHSS
SENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEMVEIKDSVSEATRDQDGVLRRT
TRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENSLAEDKDGRRKGKASIKDPHFLN
FNKKLSSSSSALLHKDTSQGDTIVSTAHMSVTGEQLGMSSPRGGRTTSNATSNCQENPCP
SKSLSPKQHLAPDPVVNPTQDLHGVKIKEKGNPEDFVEGKSILSGSVLSHSNLEIKNLEG
NRGKGRAATSFSLSDVSMLCSDIPDLHSTAILQESVISHLIDNVTLTNENEPGSSISALI
GQFDETNNQALTVVSHLHNTSVMSGHCPLPSLGLKMPIKHGFCKGKSKSSFLCSSPELIA
LSSSETTKHATNTVYETTCTPISKTKPDDDLSSKAKTAALESNLPGSPNTSRGWLPKSPT
KGEDWETLKSCSPASSPDLTLEDVIADPTLCFNSGESSLVEIDGESENLSLTTCEYRREG
TSQLASPLKLKYNQGVVEHFQRGLRNGYCKETLRPSVPEIFNNIQDVKTQSISYLAYQGA
GFVHNHFSDSDAKMFQTCVPQQSSAQDMHVPVPKQLAHLPLPALKLPSPCKSKSLGDLTS
EDIACNFESKYQCISKSFVTTGIRDKKGVTVKTKSLEPIDALTEQLRKLVSFDQEDNCQV
LYSKQDANQLPRALVRKLSSRSQSRVRNIASRAKEKQEANKQKVPNPSNGAGVVLRNKPS
APTPAVNRHSTGSYIAGYLKNTKGGGLEGRGIPEGACTALHYGHVDQFCSDNSVLQTEPS
SDDKPEIYFLLRL
NT seq
5082 nt
NT seq
+upstream
nt +downstream
nt
atggcagaccttgaagtgtataaaaacttaagtccagaaaaagttgaaagatgcatgagt
gtgatgcagtccgggacacagatgatcaagctgaaacgtggaaccaaagggcttgtccgc
ctcttttacctggatgagcaccggacacgcctccgatggcgaccctctaggaagagtgag
aaggcaaaaatacttattgattccatttacaaagtgactgagggccggcagtctgaaata
ttccacagacaagctgaggggaacttcgaccccagctgctgcttcaccatctaccatggc
aaccacatggagtccctggacctcatcacctccaaccccgaggaggcccgcacctggatc
acaggcctcaagtacctgatggctggcatcagtgatgaagactcccttgccaaaaggcag
aggacccatgaccaatgggtgaagcagacctttgaggaagctgataagaatggtgacggc
ttgctgaatattgaagagatacatcagctgatgcataaactgaatgttaatctgccccga
agaaaagtcagacaaatgtttcaggaagccgacacagatgagaatcagggaactttgaca
tttgaagagttctgtgttttttacaaaatgatgtctttgagacgagacctttatttgtta
cttttgagctacagtgacaagaaagatcacctaactgtggaagaactggctcagtttttg
aaggtggagcaaaagatgaataatgtgacaacggactattgtcttgacatcataaagaag
tttgaagtttcagaagaaaataaggtgaaaaatgttcttggcatagaaggcttcacgaac
ttcatgcgtagtcctgcctgtgacatatttaacccattgcaccatgaagtgtaccaagac
atggatcagcccctctgcaactactacattgcttcctctcacaatacatacctgactgga
gaccagctcctttctcagtccaaagtggatatgtatgcacgggtgctgcaagagggctgt
cgctgtgtggaagttgactgttgggatggcccagatggagagccagtagtacatcatggt
tacactctcacttcaaaaattctcttcagagatgttgtggagaccatcaacaagcatgcc
tttgtgaagaatgagtttcctgttatattgtctatcgagaatcactgcagtatccagcag
caaaggaagattgctcagtacctgaaaggaatattcggagacaaactggacctgtcatct
gttgatacaggggagtgcaagcagcttccaagccctcaaagtttgaaaggcaaaattcta
gtgaagggtaagaagttgccttatcaccttggggatgatgcagaggaaggggaagtttct
gatgaggacagtgcagatgaaattgaagacgagtgcaaattcaagctccattatagtaat
gggaccactgagcatcaggtggaatctttcataaggaaaaaactggagtcactgttaaaa
gaatctcaaattcgagataaagaagatcctgatagtttcacagtgcgggcactactgaag
gccacgcatgaaggcttaaatgcacacctgaagcagagtccagatgtaaaggaaagtgga
aagaaatcacatggacgatccctcatgaccaactttggaaaacataagaaaactacaaaa
tcacggtctaaatcttacagtactgatgatgaggaagacacacagcagagtactggcaag
gagggtggccagctgtacagattgggtcgccgaaggaaaaccatgaagctctgccgagaa
ctctctgatttggttgtgtacacaaactccgtggccgctcaggacattgtggatgacgga
accacaggaaatgtgttatcattcagtgaaacaagagcacatcaggttgttcagcaaaaa
tcagagcagttcatgatttataatcaaaagcaactcacgaggatttacccctctgcctac
cgcattgattccagtaacttcaaccctctcccctactggaacgcaggctgccagctagtg
gcactgaattatcaatctgaaggacgaatgatgcagttaaaccgagccaaattcaaggca
aatggcaattgtggctatgtcctcaaaccccagcaaatgtgcaaaggtactttcaaccct
ttctctggtgaccctcttcctgccaaccccaaaaagcagctcatcctgaaagttatcagt
ggacagcaactccccaaacctccagactccatgtttggagatcgaggcgagatcattgac
ccttttgttgaagttgaaattattggattgccagtagattgttgtaaagatcaaacccgt
gtggtagatgacaatggatttaaccctgtgtgggaagaaacactgacatttacagtacac
atgccagaaatagctttggttcggttccttgtgtgggatcacgatcccattggacgagac
tttgttggacaaagaactgtgaccttcagcagcttagtgcctggctaccggcatgtctat
ttggaaggactgacagaagcatccatatttgtacacataaccatcaatgaaatctatgga
aagtggagccctttaatactcaaccccagttatactatattgcactttctaggagctaca
aagaacagacaactccagggtctgaagggactgttcaataagaatcctaggcacagttct
tcagaaaacaattcccattatgtacggaagcgatccattggagatagaattctgcgacgc
acagctagcgccccagccaaaggcaggaaaaagagcaaaatgggcttccaagaaatggtg
gagataaaggattctgtgtccgaggccacaagagatcaagatggcgtgctgaggaggacc
acacgcagtttgcaagcacgccctgtctctatgcctgttgacagaaaccttctgggagct
ttgtcgctgcctgtatctgaaacagcaaaagacattgaaggaaaagaaaactctctagca
gaagataaagatggcagaagaaaagggaaagcaagtataaaagatccacattttctaaat
ttcaacaaaaagttatcatcctcctccagtgctctgctccacaaagataccagccaaggg
gacaccattgtatctactgcccacatgtcagtcacaggagaacagctgggcatgtcaagt
cctaggggtgggagaaccacatcaaatgccacaagcaattgccaggaaaacccctgtccc
agcaagtctctctccccaaagcagcatttggctcccgatcctgtagttaaccccacacaa
gatctgcatggtgtgaaaatcaaggaaaagggtaatcctgaggactttgtggaagggaaa
agcatcttgtcaggaagcgtcctttctcatagcaacctagaaattaagaacctggaaggt
aataggggtaagggccgagctgcaacatccttttctttgtcagacgtctccatgctctgt
tctgacatacctgacctacattcaactgcaattctgcaggagagtgtaatttcccatctt
attgacaatgtcactttaacaaatgagaatgagccgggcagttccatctcagccctgatt
ggccagtttgatgagaccaacaatcaggctctcacagttgtttctcatcttcataatacc
agtgtgatgtcaggccattgtcccttgcctagcctgggcctaaaaatgcccatcaagcat
ggtttttgcaagggaaaatccaagtcttccttcctgtgctcatctccggagctgatagca
ctctcgagttctgagaccaccaaacatgcaacgaacacagtttatgaaactacctgcact
cccatctctaaaaccaaaccagatgatgacctttctagtaaggccaagacagcggcctta
gaaagcaacctgcctggatcccctaatacttctcgtggctggttaccaaaaagtcctacc
aagggagaagactgggaaacactgaagagctgcagccctgcctcttcccctgatttgacc
ctggaggatgtaatagctgatcccactctctgtttcaattctggggagagcagccttgtg
gaaattgatggagaatcagaaaatctttctctaacaacctgtgaatataggagagagggc
acaagtcaacttgcttctcctttaaaactcaagtacaatcagggtgtggtagaacacttt
caaagaggtttgagaaacggctactgtaaagagaccctccgcccttctgtccctgaaata
ttcaacaatattcaagatgtcaaaactcaaagtatttcttatctagcctatcagggtgct
ggctttgtgcataatcatttctcagattcagatgcaaaaatgttccagacctgtgtgccc
cagcaatctagtgctcaagatatgcatgtccctgtacccaagcagttggcacatcttcct
ttgcctgctctgaaactgcctagtccttgcaaatccaaaagtctgggggacttaacatca
gaggacattgcctgcaattttgagagcaagtaccagtgtattagtaagagttttgttaca
actggcattagagacaagaagggcgtgactgtgaagacaaagtcgttagagcctatagat
gccctgaccgagcagcttcggaagcttgtgtcctttgaccaggaagacaactgccaagtg
ctatattcaaagcaggatgccaatcagctcccccgggcactggtcaggaagttgtcatcc
agaagtcagagcagagtgcgcaatattgctagtcgtgccaaggagaaacaggaagccaac
aagcagaaagttccaaaccccagcaatggggcaggagtggttcttagaaacaaaccctca
gcacccacccctgcagtgaatcgccactccaccggctcctacatcgcaggctacctgaag
aacacgaaagggggtggccttgaaggccggggcatcccagagggggcatgcacggctctt
cactatggccacgttgaccagttttgttcagataattctgttttgcagactgagccaagc
agtgatgataaaccagaaatttattttcttttgagactgtga
DBGET
integrated database retrieval system
