Homo sapiens (human): 23019
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Entry
23019 CDS
T01001
Symbol
CNOT1, AD-005, CDC39, HPE12, NOT1, NOT1H, VIBOS
Name
(RefSeq) CCR4-NOT transcription complex subunit 1
KO
K12604
CCR4-NOT transcription complex subunit 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03018
RNA degradation
Disease
H00267
Holoprosencephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
23019 (CNOT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
23019 (CNOT1)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
P-body specific factors
23019 (CNOT1)
mRNA degradation factors
3'-5' decay
Ccr4-NOT complex
23019 (CNOT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Not1
CNOT1_CAF1_bind
CNOT1_TTP_bind
DUF3819
CNOT1_HEAT
CNOT1_1st
Motif
Other DBs
NCBI-GeneID:
23019
NCBI-ProteinID:
NP_057368
OMIM:
604917
HGNC:
7877
Ensembl:
ENSG00000125107
Pharos:
A5YKK6
(Tbio)
UniProt:
A5YKK6
Structure
PDB
LinkDB
All DBs
Position
16:complement(58519951..58629826)
Genome browser
AA seq
2376 aa
AA seq
DB search
MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGD
GKSSGKDFHQTQFLIQECALLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLK
LSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEV
LHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRIL
PDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIVQFGVREVTAAQVARVLGMMART
HSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLNFKEVTYE
LDHPGFQIRDSKGLHNVVYGIQRGLGMEVFPVDLIYRPWKHAEGQLSFIQHSLINPEIFC
FADYPCHTVATDILKAPPEDDNREIATWKSLDLIESLLRLAEVGQYEQVKQLFSFPIKHC
PDMLVLALLQINTSWHTLRHELISTLMPIFLGNHPNSAIILHYAWHGQGQSPSIRQLIMH
AMAEWYMRGEQYDQAKLSRILDVAQDLKALSMLLNGTPFAFVIDLAALASRREYLKLDKW
LTDKIREHGEPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAG
SVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMTSL
SIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLPVGG
LGTGSLTGIGTGALGLPAVNNDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHF
SKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYR
FFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDR
FKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQA
QAQAQVPAKAPLAGQVSTMVTTSTTTTVAKTVTVTRPTGVSFKKDVPPSINTTNIDTLLV
ATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVS
IEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLG
MITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSVVFRPPNPWTM
AIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDEQLSAPK
KDVKQPEELPPITTTTTSTTPATNTTCTATVPPQPQYSYHDINVYSLAGLAPHITLNPTI
PLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDFALDSEESRMRIA
AHHMMRNLTAGMAMITCREPLLMSISTNLKNSFASALRTASPQQREMMDQAAAQLAQDNC
ELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRRYCDPVVLTYQAERMPEQIRLK
VGGVDPKQLAVYEEFARNVPGFLPTNDLSQPTGFLAQPMKQAWATDDVAQIYDKCITELE
QHLHAIPPTLAMNPQAQALRSLLEVVVLSRNSRDAIAALGLLQKAVEGLLDATSGADADL
LLRYRECHLLVLKALQDGRAYGSPWCNKQITRCLIECRDEYKYNVEAVELLIRNHLVNMQ
QYDLHLAQSMENGLNYMAVAFAMQLVKILLVDERSVAHVTEADLFHTIETLMRINAHSRG
NAPEGLPQLMEVVRSNYEAMIDRAHGGPNFMMHSGISQASEYDDPPGLREKAEYLLREWV
NLYHSAAAGRDSTKAFSAFVGQMHQQGILKTDDLITRFFRLCTEMCVEISYRAQAEQQHN
PAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDV
RQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLE
LISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLL
VLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINI
APRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVL
YVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSH
THYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNH
EFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS
NT seq
7131 nt
NT seq
+upstream
nt +downstream
nt
atgaatcttgactcgctctcgctggccttgtctcaaatcagctacctggtggacaattta
accaagaaaaattaccgagccagccagcaggaaatacagcatattgtgaatcggcacggt
cctgaggcagacaggcatttattacgctgcctattttcgcatgtggatttcagtggcgat
ggtaaaagcagtggcaaagatttccatcagactcagtttctgattcaggagtgtgcgttg
ctgattacaaagccaaattttatctcgacgctgtcctatgccattgataatccattgcac
tatcagaagagtttaaagcctgcaccccacttatttgcccagctgagtaaagtgctcaaa
ttaagcaaagtacaagaggtaatttttggccttgccctgttgaattcttccagctcagat
cttagaggtttcgctgcccagtttatcaaacagaagcttccagatcttctgcgttcttac
attgacgcagacgtcagtggaaatcaagaaggtggcttccaagatatagcaatagaggtc
ctacacctcctcctctcccatctcctctttgggcagaagggagcctttggagttggacaa
gaacagatagacgcttttcttaagacgctgcgcagagattttccccaagaacgctgtccc
gtggtgctcgcaccacttttataccctgaaaaacgggacattctaatggacaggatcctg
cctgattccggaggggtagctaaaaccatgatggagagctctttggctgatttcatgcaa
gaagtaggctatggcttttgtgcaagtattgaagaatgtcgcaatataatcgtgcagttt
ggtgttcgggaggtcacagctgcccaggttgcaagggttttgggaatgatggctcgaact
cattcaggattaacagatggcattccattacagagtatttctgctccgggcagtgggatc
tggagtgatgggaaagataaaagtgatggagcacaggcacacacatggaatgtagaagtc
ttgattgacgttcttaaagaactgaatccaagtttgaatttcaaggaagtaacttatgaa
ctggaccatcctggatttcaaattcgtgacagtaaaggacttcataatgtggtttatggc
attcagaggggtttgggtatggaagtgttcccagtagacctcatatatagaccttggaaa
catgctgaaggccagctctccttcattcaacattcccttataaatccagagatcttctgt
tttgctgactatccctgtcatactgttgccactgatattctgaaagcaccaccagaggat
gacaatcgagaaattgccacatggaagagcttggatttgattgaatctctgctgaggctt
gcagaggttgggcagtatgagcaagtcaaacagctcttcagcttccctatcaaacactgt
ccagacatgctggtattggccttactacaaattaacacctcttggcataccttgcgccat
gaacttatctccactctgatgccaattttccttggaaaccatcctaactcagctattatt
ttgcactatgcatggcatgggcagggacagtctccctcaattcgccaacttatcatgcat
gcaatggcagaatggtacatgagaggggagcagtatgatcaggccaaattgtctcgaata
cttgatgtggcccaggacttgaaggccttgtcaatgctgctaaatggtactccatttgcc
tttgttattgaccttgctgcacttgcttcacgtcgtgaatacctcaaacttgataagtgg
ctcacagataaaattcgagagcatggggagccttttatccaggcgtgtatgactttttta
aagagacggtgtccttctattttgggcggacttgccccagaaaaagaccagcccaaaagt
gctcaacttcctccagaaactttggcgacaatgttggcctgtctgcaagcttgtgcaggg
agtgtttctcaggagctatcagaaactatcctcaccatggtagccaattgcagtaatgtt
atgaataaggccagacaaccaccacctggagttatgccaaaaggacgtcctcctagtgct
agcagcttagatgccatttctcctgttcagattgaccctcttgctggaatgacatctctt
agtataggtggttcagctgcccctcacacccagagtatgcagggttttcctccaaatttg
ggttctgcattcagtacccctcagtcaccagcaaaagcatttccacccctttcaaccccc
aatcagaccactgcattcagtggtattggaggactttcatcacagcttccagtaggtggt
cttggcacaggcagcctgactggtataggaactggtgctcttggactccctgcagtgaat
aacgacccttttgtacagaggaaactgggcacctctggactgaatcagcctacattccag
cagagtaagatgaaaccttcggacttgtctcaggtgtggccagaggcaaaccagcacttt
agtaaagagatagatgatgaagcaaacagctatttccagcgaatatataatcatccacca
catccaaccatgtctgttgatgaggtattagaaatgctgcagagatttaaagactctact
ataaagagggaacgagaagtatttaactgtatgctaaggaacttgtttgaagaatatcgt
ttttttccccagtatcctgataaagagttacatataacagcctgcctatttggtggtata
attgagaaaggactggtcacttacatggcactaggtctggctctacgatatgttcttgaa
gccttacgcaagccttttggatccaaaatgtattatttcgggattgctgcactagataga
tttaaaaacagattgaaggactatccccagtattgtcagcatttggcttctatcagtcac
tttatgcaatttccacatcatttacaggagtatattgagtatggacagcagtctagagat
cctcctgtgaaaatgcaaggctctatcacaacccctggaagtattgcactggctcaggcc
caggctcaggcccaggttccagcaaaagctcctcttgctggtcaagttagcactatggta
accacctcaacaactaccactgttgctaaaacggttacggtcaccaggccaactggagtc
agctttaagaaagatgtgccaccttctattaatactacaaatatagatacgttgcttgtg
gccacagatcaaactgagagaattgtggagcccccagaaaatatccaggagaaaattgct
tttattttcaataatctctcacagtcaaatatgacacaaaaggttgaagagctaaaggaa
acggtgaaagaagaatttatgccttgggtttcacagtatctggttatgaagagagtcagt
attgagccaaactttcatagcctgtattcaaacttccttgacacgctgaagaatcctgaa
tttaacaagatggttctgaatgagacctacagaaacattaaagtgctcctgacctctgat
aaagctgcagccaatttctcagatcgttctttgctgaagaacttgggacattggctagga
atgatcacattagctaaaaacaaacccatcttacacactgacttggatgtgaaatcattg
ctgctagaggcttatgttaaaggacaacaagaattgctctatgtagtgccctttgttgcc
aaagtcttagaatctagcattcgtagtgtggtttttaggccaccaaacccttggacaatg
gcaattatgaatgtattagctgagctacatcaggagcatgacttaaagttaaacttgaag
tttgaaatcgaggttctctgcaagaaccttgcattagacatcaatgagctaaaacctgga
aacctcctaaaggataaagatcgcctgaagaatttagatgagcaactctctgctccaaag
aaagatgtcaagcagccagaagaactccctcccatcacaaccacaacaacttctactaca
ccagctaccaacaccacttgtacagccacggttccaccacagccacagtacagctaccac
gacatcaatgtctattcccttgcgggcttggcaccacacattactctgaatccaacaatt
cccttgtttcaggcccatccacagttgaagcagtgtgtgcgtcaggcaattgaacgggct
gtccaggagctggtccatcctgtggtggatcgatcaattaagattgccatgactacttgt
gagcaaatagtcaggaaggattttgccctggattcggaggaatctcgaatgcgaatagca
gctcatcacatgatgcgtaacttgacagctggaatggctatgattacatgcagggaacct
ttgctcatgagcatatctaccaacttaaaaaacagttttgcctcagcccttcgtactgct
tccccacaacaaagagaaatgatggatcaggcagctgctcaattagctcaggacaattgt
gagttggcttgctgttttattcagaagactgcagtagaaaaagcaggccctgagatggac
aagagattagcaactgaatttgagctgagaaaacatgctaggcaagaaggacgcagatac
tgtgatcctgttgttttaacatatcaagctgaacggatgccagagcaaatcaggctgaaa
gttggtggtgtggacccaaagcagttggctgtttacgaagagtttgcacgcaatgttcct
ggcttcttacctacaaatgacttaagtcagcccacgggatttttagcccagcccatgaag
caagcttgggcaacagatgatgtagctcagatttatgataagtgtattacagaactggag
caacatctacatgccatcccaccaactttggccatgaaccctcaagctcaggctcttcga
agtctcttggaggttgtagttttatctcgaaactctcgggatgccatagctgctcttgga
ttgctccaaaaggctgtagagggcttactagatgccacaagtggtgctgatgctgacctt
ctgctgcgctacagggaatgccacctcttggtcctaaaagctctgcaggatggccgggca
tatgggtctccatggtgcaacaaacagatcacaaggtgcctaattgaatgtcgagatgaa
tataaatataatgtggaggctgtggagctgctaattcgcaatcatttggttaatatgcag
cagtatgatcttcacctagcgcagtcaatggagaatggcttaaactacatggctgtggca
tttgctatgcagttagtaaaaatcctgctggtggatgaaaggagtgttgctcatgttact
gaggcagatctgttccacaccattgaaaccctcatgaggattaatgctcattccagaggc
aatgctccagaaggattgccccagctgatggaagtagtgcgatccaactatgaagcaatg
attgatcgtgctcatggaggcccaaactttatgatgcattctgggatctctcaagcctca
gagtatgatgaccctccaggcctgagggagaaggcagagtatcttctgagggaatgggtg
aatctctaccattcagcagcagctggccgcgacagtaccaaagctttctctgcatttgtt
ggacagatgcaccagcaaggaatactgaagaccgatgatctcataacaaggttctttcgt
ctgtgtactgaaatgtgtgttgaaatcagttaccgtgctcaggctgagcagcagcacaat
cctgctgccaatcccaccatgatccgagccaagtgctatcacaacctggatgcctttgtt
cgactcattgcactgctcgtgaaacactcaggggaggccaccaacactgtcacaaagatt
aatctgctgaacaaggtccttggtatagtagtgggagttctccttcaggatcatgatgtt
cgtcagagtgaatttcagcaacttccctaccatcgaatttttatcatgcttctcttggaa
ctcaatgcacctgagcatgtgttggaaaccattaatttccagacacttacagctttctgc
aatacattccacatcttgaggcctaccaaagctcctggctttgtatatgcctggcttgaa
ctgatttcccatcggatatttattgcaagaatgctggcacatacgccacagcagaagggg
tggcctatgtatgcacagctactgattgatttattcaaatatttagcgcctttccttaga
aatgtggaactcaccaaacctatgcaaatcctctacaagggcactttaagagtgctgctg
gttcttttgcatgatttcccagagttcctttgtgattaccattatgggttctgtgatgtg
atcccacctaattgtatccagttaagaaatttgatcctgagtgcctttccaagaaacatg
aggctccccgacccattcactcctaatctaaaggtggacatgttgagtgaaattaacatt
gctccccggattctcaccaatttcactggagtaatgccacctcagttcaaaaaggatttg
gattcctatcttaaaactcgatcaccagtcactttcctgtctgatctgcgcagcaaccta
caggtatccaatgaacctgggaatcgctacaacctccagctcatcaatgcactggtgctc
tatgtcgggactcaggccattgcgcacatccacaacaagggcagcacaccttcaatgagc
accatcactcactcagcacacatggatatcttccagaatttggctgtggacttggacact
gagggtcgctatctctttttgaatgcaattgcaaatcagctccggtacccaaatagccac
actcactacttcagttgcaccatgctgtacctttttgcagaggccaatacggaagccatc
caagaacagatcacaagagttctcttggaacggttgattgtaaataggccacatccttgg
ggtcttcttattaccttcattgagctgattaaaaacccagcgtttaagttctggaaccat
gaatttgtacactgtgccccagaaatcgaaaagttattccagtcggtcgcacagtgctgc
atgggacagaagcaggcccagcaagtaatggaagggacaggtgccagttag
DBGET
integrated database retrieval system
