Homo sapiens (human): 23025 Help Entry 23025             CDS       T01001                                  Symbol UNC13A, Munc13-1 Name (RefSeq) protein unc-13 homolog A isoform 1   KO K15293   protein unc-13 A/B/C Organism hsa  Homo sapiens (human) Pathway hsa04721   Synaptic vesicle cycle Network nt06541  Cytoskeleton in neurons   Element N01856   Cytomatrix at the active zone (CAZ) protein complex Disease H03026   Neurodevelopmental disorder with hypotonia, epilepsy, and absent speech H03027   Neurodevelopmental disorder with speech delay, movement abnormalities, and seizures H03028   Intellectual development disorder with seizures and dysmorphic facies Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09156 Nervous system    04721 Synaptic vesicle cycle     23025 (UNC13A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     23025 (UNC13A) Membrane trafficking [BR:hsa04131]  SNARE   SNARE associated proteins    Syntaxin-binding proteins     23025 (UNC13A) SSDB OrthologParalogGFIT Motif Pfam:  MUN C2 C1_1 COG2_C Exo70_C APG6_N Motif Other DBs NCBI-GeneID:  23025 NCBI-ProteinID:  NP_001073890 OMIM:  609894 HGNC:  23150 Ensembl:  ENSP00000429562.2 UniProt:  Q9UPW8 LinkDB All DBs Position 19:complement(17601336..17688354) Genome browser AA seq 1703 aa AA seqDB search MSLLCVGVKKAKFDGAQEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGL TVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQVIMADSEICGTKDPTFHR ILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQCCNWNYF GWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYS DSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDS YHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQ REDVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKVAPKPATPDKVPAAEQIPEA EPPKDEESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGG PGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKT LQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLN ADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQM KAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLN PVWEENFHFECHNSSDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMD VWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVK IPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTL LANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSP ERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYS REYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVG KISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPE YPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSF EIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKVPCILMNNTQ QLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMG DILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWK LVMNTMEKTIVLPPLTDQTMIGNLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLS KLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSL YTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQ TSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVC VKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEV AKEFVKLKSDTRSAEEGGAAPAP NT seq 5112 nt NT seq  +upstreamnt  +downstreamnt atgtctctgctttgcgttggagtcaaaaaagccaagtttgatggtgcccaagagaaattc aacacgtacgtgaccctgaaagtgcagaatgtcaagagcacgaccatcgcggtgcggggc agccagcccagctgggagcaggatttcatgttcgagattaaccgtctggatttgggactg acggtggaggtgtggaataagggtctcatctgggacacaatggtgggcactgtgtggatc ccactgaggaccatccgccagtccaatgaggagggccctggagagtggctgacgctggac tcccaggtcatcatggcagacagtgagatctgtggcaccaaggaccccaccttccaccgc atcctcctggacacgcgctttgagctacccttagacattcctgaagaggaggctcgctac tgggccaagaagctggagcagctcaatgctatgcgggaccaggatgaatattcgttccaa gatgagcaagacaagcctctgcctgtccccagcaaccagtgctgcaactggaattatttt ggctggggtgagcagcacaacgatgaccccgacagtgcagtggatgatcgtgacagtgac taccgcagtgaaacgagcaacagcatcccgccgccctattatactacgtcacaacccaac gcctcagtccaccaatattctgttcgcccaccacccctgggctcccgggagtcctacagt gactccatgcacagttacgaggagttctctgagccacaagccctcagccccacgggtagc agccgctatgcctcttccggggagctgagccagggaagctctcagctgagcgaggacttc gaccctgacgagcacagcctgcagggctccgacatggaggatgagcgggaccgggactcc taccactcctgccacagctcggtcagctaccacaaagactcgcctcgctgggaccaggat gaggaagagctggaggaggacctggaggacttcctggaggaggaggagctgcctgaagat gaggaggagctggaggaggaggaggaggaggtgcctgacgatttgggcagctatgcccag cgtgaagacgtagctgtggctgagcccaaagacttcaaacgcatcagcctcccgccagct gccccagggaaggaggacaaggccccagtggcacccaccgaggcccccgacatggccaag gtggcccccaagccagccacgcccgacaaggtgcctgcagctgagcagatccctgaggct gagccacccaaggacgaggagagtttcaggccgagagaggatgaggaaggccaggagggg caggactccatgtccagggccaaggccaactggctgcgtgccttcaacaaggtgcggatg cagctgcaggaggcccggggagaaggagagatgtctaaatccctatggttcaaaggcggc ccagggggcggtctcatcatcatcgacagcatgccagacatccgcaagaggaaacctatc ccactcgtgagcgacttggccatgtccctggtccagtccaggaaagcgggcatcacctcg gccttggcctccagcacgttgaacaacgaggagctgaaaaaccacgtttacaagaagacc ctgcaagccttaatctaccccatctcgtgcacgacgccacacaacttcgaagtgtggacg gccaccacgcccacctactgctacgagtgcgaggggctgctgtggggcatcgcgaggcag ggcatgcgctgcaccgagtgcggtgtcaagtgccacgagaagtgccaggacctgctcaac gccgactgcctgcagcgggctgcggagaagagctccaagcacggggcggaggaccggaca cagaacatcatcatggtgctcaaggaccgcatgaagatccgggagcgcaacaagcccgag atcttcgagctcatccaggagatcttcgcggtgaccaagacggcgcacacgcagcagatg aaggcggtcaagcagagcgtgctggacggcacgtccaagtggtccgccaagatcagcatc accgtggtctgcgcccagggcttgcaggcaaaggacaagacaggatccagtgacccctat gtcaccgtccaggtcgggaagaccaagaaacggacaaaaaccatctatgggaacctcaac ccggtgtgggaggagaatttccactttgaatgtcacaattcctccgaccgcatcaaggtg cgcgtctgggacgaggatgacgacatcaaatcccgcgtgaaacagaggttcaagagggaa tctgacgatttcctggggcagacgatcattgaggtgcggacgctcagcggcgagatggac gtgtggtacaacctggacaagcgaactgacaaatctgccgtgtcgggtgccatccggctc cacatcagtgtggagatcaaaggcgaggagaaggtggccccgtaccatgtccagtacacc tgtctgcatgagaacctgttccacttcgtgaccgacgtgcagaacaatggggtcgtgaag atcccagatgccaagggtgacgatgcctggaaggtttactacgatgagacagcccaggag attgtggacgagtttgccatgcgctacggcgtcgagtccatctaccaagccatgacccac tttgcctgcctctcctccaagtatatgtgcccaggggtgcctgccgtcatgagcaccctg ctcgccaacatcaatgcctactacgcacacaccaccgcctccaccaacgtgtctgcctcc gaccgcttcgccgcctccaactttgggaaagagcgcttcgtgaaactcctggaccagctg cataactccctgcggattgacctctccatgtaccggaataacttcccagccagcagcccg gagagactccaggacctcaaatccactgtggaccttctcaccagcatcaccttctttcgg atgaaggtacaagaactccagagcccgccccgagccagccaggtggtaaaggactgtgtg aaagcctgccttaattctacctacgagtacatcttcaataactgccatgaactgtacagc cgggagtaccagacagacccggccaagaagggggaagttctcccagaggaacaggggccc agcatcaagaacctcgacttctggtccaagctgattaccctcatagtgtccatcattgag gaagacaagaattcctacactccctgcctcaaccagtttccccaggagctgaatgtgggt aaaatcagcgctgaagtgatgtggaatctgtttgcccaagacatgaagtacgccatggag gagcacgacaagcatcgtctatgcaagagtgccgactacatgaacctccacttcaaggtg aaatggctctacaatgagtatgtgacggaacttcccgccttcaaggaccgcgtgcctgag taccctgcatggtttgaacccttcgtcatccagtggctggatgagaatgaggaggtgtcc cgggatttcctgcacggtgccctggagcgagacaagaaggatgggttccagcagacctca gagcatgccctattctcctgctccgtggtggatgttttctcccaactcaaccagagcttt gaaatcatcaagaaactcgagtgtcccgaccctcagatcgtggggcactacatgaggcgc tttgccaagaccatcagtaatgtgctcctccagtatgcagacatcatctccaaggacttt gcctcctactgctccaaggagaaggagaaagtgccctgcattctcatgaataacactcaa cagctacgagttcagctggagaagatgttcgaagccatgggaggaaaggagctggatgct gaagccagtgacatcctgaaggagcttcaggtgaaactcaataacgtcttggatgagctc agccgggtgtttgctaccagcttccagccgcacattgaagagtgtgtcaaacagatgggt gacatccttagccaggttaagggcacaggcaatgtgccagccagtgcctgcagcagcgtg gcccaggacgcggacaatgtgttgcagcccatcatggacctgctggacagcaacctgacc ctctttgccaaaatctgtgagaagactgtgctgaagcgagtgctgaaggagctgtggaag ctggttatgaacaccatggagaaaaccatcgtcctgccgcccctcactgaccagacgatg atcgggaacctcttgagaaaacatggcaagggattagaaaagggcagggtgaaattgcca agccactcagacggaacccagatgatcttcaatgcagccaaggagctgggtcagctgtcc aaactcaaggatcacatggtacgagaagaagccaagagcttgaccccaaagcagtgcgcg gttgttgagttggccctggacaccatcaagcaatatttccacgcgggtggcgtgggcctc aagaagaccttcctggagaagagcccggacctgcaatccttgcgctatgccctgtcgctc tacacgcaggccaccgacctgctaatcaagacctttgtacagacgcaatcggcccagggc ttgggtgtagaagaccctgtgggtgaagtctctgtccatgttgagctgttcactcatcca ggaactggggaacacaaggtcacagtgaaagtggtggctgccaatgacctcaagtggcag acttctggcatcttccggccgttcatcgaggtcaacatcattgggccccagctcagcgac aagaaacgcaagtttgcgaccaaatccaagaacaatagctgggctcccaagtacaatgag agcttccagttcacgctgagcgccgacgcgggtcccgagtgctatgagctgcaggtgtgc gtcaaggactactgcttcgcgcgcgaggaccgcacggtggggctggccgtgctgcagctg cgtgagctggcccagcgcgggagcgccgcctgctggctgccgctcggccgccgcatccac atggacgacacgggcctcacggtgctgcgaatcctctcgcagcgcagcaacgacgaggtg gccaaggagttcgtgaagctcaagtcggacacgcgctccgccgaggagggcggtgccgcg cctgcgccttag

Homo sapiens (human): 10497 Help Entry 10497             CDS       T01001                                  Symbol UNC13B, MUNC13, UNC13, Unc13h2, munc13-2 Name (RefSeq) protein unc-13 homolog B isoform 1   KO K15293   protein unc-13 A/B/C Organism hsa  Homo sapiens (human) Pathway hsa04721   Synaptic vesicle cycle Network nt06541  Cytoskeleton in neurons   Element N01856   Cytomatrix at the active zone (CAZ) protein complex Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09156 Nervous system    04721 Synaptic vesicle cycle     10497 (UNC13B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     10497 (UNC13B) Membrane trafficking [BR:hsa04131]  SNARE   SNARE associated proteins    Syntaxin-binding proteins     10497 (UNC13B) SSDB OrthologParalogGFIT Motif Pfam:  MUN C2 C1_1 TPR_PATROL1 COG2_C C2_CAPS Motif Other DBs NCBI-GeneID:  10497 NCBI-ProteinID:  NP_006368 OMIM:  605836 HGNC:  12566 UniProt:  O14795 Q4LE73 LinkDB All DBs Position 9:35162009..35405335 Genome browser AA seq 1591 aa AA seqDB search MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGL SVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHK ILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDP DSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSM QSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSH SLSRDGQAGFGEQEKPLEVTGQAEKEAACEPKEMKEDATTHPPPDLVLQKDHFLGPQESF PEENASSPFTQARAHWIRAVTKVRLQLQEIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLR RKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNF EVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGA EDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSA KITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSSD RIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSG AIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDE TAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTN VSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSI TFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGP SIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALE EHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVS LEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRR FAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLRVQLEKMFEAMGGKELDLEA ADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQ DADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQ LIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEK SPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHKV TVKVVAANDLKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLG NEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVTAKGSCACWCPLGRKIHMDETGLT ILRILSQRSNDEVAREFVKLKSESRSTEEGS NT seq 4776 nt NT seq  +upstreamnt  +downstreamnt atgtcactgctctgcgtgcgcgttaaaagggccaaattccagggttcaccagataaattt aacacatatgtgaccctgaaagtacagaatgtgaagagcacaactgtagcagttcgtggt gatcagccttcctgggaacaggatttcatgtttgagattagtcgcctggacctgggtcta agtgtggaggtatggaacaaaggactgatctgggacaccatggtggggactgtgtggatt gcgctgaagactattcgtcagtcggatgaggaagggcctggggaatggtccacattagag gcagagacgttaatgaaagacgatgagatctgtggaactagaaacccaactcctcataaa attttgcttgatacaagatttgagttgccttttgatatcccagaggaggaagccagatat tggacctacaaatgggagcaaatcaatgccttgggagctgacaatgagtattctagtcaa gaagaaagccagaggaagccattgcccactgctgccgcccagtgttcttttgaagaccct gatagtgccgtcgatgaccgagatagtgactatcgcagtgagaccagcaacagcttccca cctccttaccatacagcttcccagcccaacgcttctgtgcaccagttccctgtgccggtg cgatcgccacagcagctgctacttcaaggcagttcccgggactcttgtaatgactctatg caaagttatgaccttgattatccagagcggcgggctatcagccccaccagcagcagtagg tatggctcctcctgtaatgtgagtcaaggaagctctcagctaagtgaactagaccagtat cacgaacaagatgacgaccatcgggagacggactcgattcattcttgccacagctctcac agcctgtccagagatggccaagcaggttttggagaacaagagaaacccttggaggtgaca ggtcaagcagagaaggaggcagcatgtgaacccaaggagatgaaagaagatgccacaacc caccctcccccagatctggtgctgcaaaaagaccacttcctaggtccccaggagagtttt cctgaggagaatgcatcttcaccatttacccaagccagagcacattggatccgagcagtt accaaggttcgactccagctgcaggagattccagatgatggtgacccctctctgcctcag tggctcccggaagggccagccggagggctctatggcattgacagcatgccagatttacgc agaaagaagccactgccacttgtcagtgatctgtcactggtccagtctcggaaggcagga atcacttctgcaatggctacacgcacttctcttaaggacgaagagctgaaatcccacgtg tataagaaaaccctgcaggccttaatctaccccatttcgtgcaccactcctcataacttt gaggtctggacggccactaccccaacctactgctatgagtgtgaaggcctgctctggggc attgcccggcagggcatgcgctgcagcgaatgtggagtcaagtgccatgagaagtgccag gatctgctcaatgctgactgcctgcagcgggctgcagaaaagagctgtaaacatggagct gaggaccggacccagaacattatcatggccatgaaggaccgcatgaagatccgagagcga aataagccagagatctttgaagttatccgggacgtcttcacagtgaacaaagctgcccat gtgcagcagatgaaaacagtgaagcagagtgtactggatggcacctccaaatggtcagcc aagatcaccattactgtggtgtgtgcccagggcctacaagccaaggacaaaacaggatcc agtgacccttacgtgactgtgcaagtcagcaaaactaagaagcgtaccaagaccattttt ggaaacttgaatcctgtttgggaggagaagttccattttgagtgccacaactcctctgac cgcattaaggtgcgtgtatgggatgaggatgatgacatcaagtcaagagtaaagcaacgc ctaaagcgagagtctgatgatttccttggccaaaccatcattgaggttcggaccctaagt ggcgagatggacgtctggtacaacttggagaagaggacagacaaatcagccgtctcaggg gctatccgactacaaatcagtgtggagatcaagggggaggagaaagtagccccataccac gtgcagtatacatgtctccatgagaatcttttccattacctcacagacattcagggcagt ggaggagtccgcatccctgaagctcgaggagacgatgcctggaaggtgtactttgatgag acagcccaagaaattgtggatgaatttgccatgcgttatggcattgagtccatatatcag gccatgacgcactttgcatgtttatcatccaagtacatgtgtcctggtgtgccagcagtg atgagcaccttactggccaacatcaacgcctactatgcccacacaactgcctctaccaat gtctctgcatctgatcgctttgcagcctccaactttgggaaagagagatttgtaaaactg ctggaccagctacacaactcactgaggatcgacctctctacatacaggaataatttccct gctgggagtcctgaacggcttcaggacttaaaatccacagtggatttgctgaccagcatt actttcttcagaatgaaggtacaagaactgcaaagccctccaagagccagccaggtggta aaggattgtgtgaaggcctgtttgaactccacatatgaatatatcttcaacaactgccac gacttatacagccgccagtaccagctgaagcaggagctacctccagaggaacaagggccc agcattcggaacctggatttctggcccaagctcatcacactcatcgtgtcaatcatagag gaagataagaattcctacacacctgttctgaaccagtttcctcaggagttgaatgtggga aaagtcagcgcagaagtgatgtggcatttgtttgcccaagacatgaaatatgcattggag gagcatgagaaagaccacctgtgtaaaagtgctgactacatgaacctgcacttcaaggtg aagtggctccacaatgaatacgtgcgggatctgcctgtcctccaggggcaggtgcctgag tacccagcgtggtttgagcagttcgtgctacaatggctggatgagaatgaggatgtatcc ctggaattcctgcgtggggccctggaacgagataagaaggatggattccagcagacatca gagcatgcactcttttcctgctctgtggtggatgtcttcacacaactcaatcagagcttt gagatcatccggaagctggaatgcccagaccccagcatccttgcccactacatgaggagg tttgctaagaccatcgggaaggtgctgatgcagtatgcagacatcttgtcaaaggacttc ccagcctattgcacaaaggagaaactgccctgcatcctgatgaacaacgtgcagcaactg agggtccagctggagaaaatgtttgaggccatgggaggcaaggagctggaccttgaagct gcagacagtctgaaggagctgcaggtgaaactgaatacggttctggatgagctcagcatg gtgtttggaaacagtttccaggtacggattgatgagtgtgttcgacaaatggccgacatc ctgggccaggttcggggcacagggaatgcatctccagacgccagggcctcagcggctcag gatgcagatagcgtactccggcctctcatggacttcctggatggcaacctcaccctcttt gccactgtgtgtgagaagacggttctgaagcgtgtactgaaggagctctggcgcgtggtg atgaacacaatggagaggatgattgttctgcccccactcactgaccagacgggcacccag ctgatcttcactgctgccaaggagctgagccatctttccaaactcaaggatcacatggta cgagaggaaacacggaatctcactccaaagcagtgtgcagtccttgacctcgccctggac accatcaagcaatacttccatgcaggaggcaatgggctgaagaaaaccttcctggagaag agcccagatctgcagtctctacgctatgccctgtctctgtacacacagactactgacact ctcatcaagacctttgtgcgctcgcagaccacccaagggtctggtgtggacgatcctgtg ggagaagtctctattcaggtggacttgtttacacaccctggtactggggagcacaaggtc acagtgaaagtggtggctgccaatgacctcaagtggcagacagcgggtatgttccggcct ttcgtggaggtgactatggttggcccacaccaaagtgataagaagaggaagttcacaacc aaatccaaaagcaacaactgggcccccaagtacaatgagacattccacttcctcctggga aatgaggaggggcccgagtcctatgagttgcagatatgcgtgaaggattactgctttgcc cgggaagatcgcgtgctagggctggctgtgatgcctctgagggatgtcacagccaagggc agctgtgcctgctggtgccccttgggccggaagatccatatggatgagacaggcctgacc attctccggattttatctcagaggagcaatgacgaggtggcccgagaatttgtgaaactc aaatcagagtctcgttccacggaggaggggagctga

Homo sapiens (human): 440279 Help Entry 440279            CDS       T01001                                  Symbol UNC13C Name (RefSeq) protein unc-13 homolog C isoform 1   KO K15293   protein unc-13 A/B/C Organism hsa  Homo sapiens (human) Pathway hsa04721   Synaptic vesicle cycle Network nt06541  Cytoskeleton in neurons   Element N01856   Cytomatrix at the active zone (CAZ) protein complex Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09156 Nervous system    04721 Synaptic vesicle cycle     440279 (UNC13C)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     440279 (UNC13C) Membrane trafficking [BR:hsa04131]  SNARE   SNARE associated proteins    Syntaxin-binding proteins     440279 (UNC13C) SSDB OrthologParalogGFIT Motif Pfam:  MUN C2 C1_1 Rab11-FIP3 C2_CAPS FCH Mua DUF2205 HH_AprE Motif Other DBs NCBI-GeneID:  440279 NCBI-ProteinID:  NP_001074003 OMIM:  614568 HGNC:  23149 Ensembl:  ENSP00000260323.11 UniProt:  Q8NB66 LinkDB All DBs Position 15:53837602..54633440 Genome browser AA seq 2214 aa AA seqDB search MVANFFKSLILPYIHKLCKGMFTKKLGNTNKNKEYRQQKKDQDFPTAGQTKSPKFSYTFK STVKKIAKCSSTHNLSTEEDEASKEFSLSPTFSYRVAIANGLQKNAKVTNSDNEDLLQEL SSIESSYSESLNELRSSTENQAQSTHTMPVRRNRKSSSSLAPSEGSSDGERTLHGLKLGA LRKLRKWKKSQECVSSDSELSTMKKSWGIRSKSLDRTVRNPKTNALEPGFSSSGCISQTH DVMEMIFKELQGISQIETELSELRGHVNALKHSIDEISSSVEVVQSEIEQLRTGFVQSRR ETRDIHDYIKHLGHMGSKASLRFLNVTEERFEYVESVVYQILIDKMGFSDAPNAIKIEFA QRIGHQRDCPNAKPRPILVYFETPQQRDSVLKKSYKLKGTGIGISTDILTHDIRERKEKG IPSSQTYESMAIKLSTPEPKIKKNNWQSPDDSDEDLESDLNRNSYAVLSKSELLTKGSTS KPSSKSHSARSKNKTANSSRISNKSDYDKISSQLPESDILEKQTTTHYADATPLWHSQSD FFTAKLSRSESDFSKLCQSYSEDFSENQFFTRTNGSSLLSSSDRELWQRKQEGTATLYDS PKDQHLNGGVQGIQGQTETENTETVDSGMSNGMVCASGDRSHYSDSQLSLHEDLSPWKEW NQGADLGLDSSTQEGFDYETNSLFDQQLDVYNKDLEYLGKCHSDLQDDSESYDLTQDDNS SPCPGLDNEPQGQWVGQYDSYQGANSNELYQNQNQLSMMYRSQSELQSDDSEDAPPKSWH SRLSIDLSDKTFSFPKFGSTLQRAKSALEVVWNKSTQSLSGYEDSGSSLMGRFRTLSQST ANESSTTLDSDVYTEPYYYKAEDEEDYTEPVADNETDYVEVMEQVLAKLENRTSITETDE QMQAYDHLSYETPYETPQDEGYDGPADDMVSEEGLEPLNETSAEMEIREDENQNIPEQPV EITKPKRIRPSFKEAALRAYKKQMAELEEKILAGDSSSVDEKARIVSGNDLDASKFSALQ VCGGAGGGLYGIDSMPDLRRKKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHV FKKTLQALIYPMSSTIPHNFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQ DLLNADCLQRAAEKSSKHGAEDKTQTIITAMKERMKIREKNRPEVFEVIQEMFQISKEDF VQFTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIF GNLNPVWDEKFYFECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLS GEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVKSN GGVKIPEVKGDEAWKVFFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAV MSTLLANINAFYAHTTVSTNIQVSASDRFAATNFGREKFIKLLDQLHNSLRIDLSKYREN FPASNTERLQDLKSTVDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDN CHELYSQLTDPSKKQDIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQE LNMGKISAEIMWTLFALDMKYALEEHENQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKD AVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSEHALFSCSVVDVFAQL NQSFEIIKKLECPNPEALSHLMRRFAKTINKVLLQYAAIVSSDFSSHCDKENVPCILMNN IQQLRVQLEKMFESMGGKELDSEASTILKELQVKLSGVLDELSVTYGESFQVIIEECIKQ MSFELNQMRANGNTTSNKNSAAMDAEIVLRSLMDFLDKTLSLSAKICEKTVLKRVLKELW KLVLNKIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKLKEHMIREDARGLTPRQCAIMEV VLATIKQYFHAGGNGLKKNFLEKSPDLQSLRYALSLYTQTTDALIKKFIDTQTSQSRSSK DAVGQISVHVDITATPGTGDHKVTVKVIAINDLNWQTTAMFRPFVEVCILGPNLGDKKRK QGTKTKSNTWSPKYNETFQFILGKENRPGAYELHLSVKDYCFAREDRIIGMTVIQLQNIA EKGSYGAWYPLLKNISMDETGLTILRILSQRTSDDVAKEFVRLKSETRSTEESA NT seq 6645 nt NT seq  +upstreamnt  +downstreamnt atggtggctaattttttcaagagcttgattttaccttacattcataagctttgcaaagga atgtttacaaagaaattgggaaatacaaacaaaaacaaagagtatcgtcagcagaaaaag gatcaagacttccccactgctggccagaccaaatcccccaaattttcttacacttttaaa agcactgtaaagaagattgcaaagtgttcatccactcacaacttatccactgaggaagac gaggccagtaaagagttttccctctcaccaacattcagttaccgagtagctattgccaat ggcctacaaaagaatgctaaagtaaccaacagtgataatgaggatctgcttcaagagctc tcttcaatcgagagttcctactcagaatcattaaatgaactaaggagtagcacagaaaac caggcacaatcaacacacacaatgccagttagacgcaacagaaagagttcaagcagcctt gcaccctctgagggcagctctgacggggagcgtactctacatggcttaaaactgggagct ttacgaaaactgagaaaatggaaaaagagtcaagaatgtgtctcctcagactcagagtta agcaccatgaaaaaatcctggggaataagaagtaagtctttggacagaactgtccgaaac ccaaagacaaatgccctggagccagggttcagttcctctggctgcattagccaaacacat gatgtcatggaaatgatctttaaggaacttcagggaataagtcagattgaaacagaactt tctgaactacgagggcacgtcaatgctctcaagcactccatcgatgagatctccagcagt gtggaggttgtacaaagtgaaattgagcagttgcgcacagggtttgtccagtctcggagg gaaactagagacatccatgattatattaagcacttaggtcatatgggtagcaaggcaagc ctgagatttttaaatgtgactgaagaaagatttgaatatgttgaaagcgtggtgtaccaa attctaatagataaaatgggtttttcagatgcaccaaatgctattaaaattgaatttgct cagaggataggacaccagagagactgcccaaatgcaaagcctcgacccatacttgtgtac tttgaaacccctcaacaaagggattctgtcttaaaaaagtcatataaactcaaaggaaca ggcattggaatctcaacagatattctaactcatgacatcagagaaagaaaagagaaaggg ataccatcctcccagacatatgagagcatggctataaagttgtctactccagagccaaaa atcaagaagaacaattggcagtcacctgatgacagtgatgaagatcttgaatctgacctc aatagaaacagttacgctgtgctttccaagtcagagcttctaacaaagggaagtacttcc aagccaagctcaaaatcacacagtgctagatccaagaataaaactgctaatagcagcaga atttcaaataaatcagattatgataaaatctcctcacagttgccagaatcagatatcttg gaaaagcaaaccacaacccattatgcagatgcaacacctctctggcactcacagagtgat tttttcactgctaaacttagtcgttctgaatcagatttttccaaattgtgtcagtcttac tcagaagatttttcagaaaatcagtttttcactagaactaatggaagctctctcctgtca tcttcggaccgggagctatggcagaggaaacaggaaggaacagcgaccctgtatgacagt cccaaggaccagcatttgaatggaggtgttcagggtatccaagggcagactgaaactgaa aacacagaaactgtggatagtggaatgagtaatggcatggtgtgtgcatctggagaccgg agtcattacagtgattctcagctctctttacatgaggatctttctccatggaaggaatgg aatcaaggagctgatttaggcttggattcatccacccaggaaggttttgattatgaaaca aacagtctttttgaccaacagcttgatgtttacaataaagacctagaatacttgggaaag tgccacagtgatcttcaagatgactcagagagctacgacttaactcaagatgacaattct tctccatgccctggcttggataatgaaccacaaggccagtgggttggccaatatgattct tatcagggagctaattctaatgagctataccaaaatcaaaaccagttgtccatgatgtat cgaagtcaaagtgaattgcaaagtgatgattcagaggatgccccacccaaatcatggcat agtcgattaagcattgacctttctgataagactttcagcttcccaaaatttggatctaca ctgcagagggctaaatcagccttggaagtagtatggaacaaaagcacacagagtctgagt gggtatgaggacagtggctcttcattaatggggagatttcggacattatctcaatcaact gcaaatgagtcaagtaccacacttgactctgatgtctacacggagccctattactataaa gcagaggatgaggaagattatactgaaccagtggctgacaatgaaacagattatgttgaa gtcatggaacaagtccttgctaaactagaaaacaggactagtattactgaaacagatgaa caaatgcaagcatatgatcacctttcatatgaaacaccttatgaaaccccacaagatgag ggttatgatggtccagcagatgatatggttagtgaagaggggttagaacccttaaatgaa acatcagctgagatggaaataagagaagatgaaaaccaaaacattcctgaacagccagtg gagatcacaaagccaaagagaattcgtccttctttcaaagaagcagctttaagggcctat aaaaagcaaatggcagagttggaagagaagatcttggctggagatagcagttctgtggat gaaaaggctcgaatagtaagtggcaatgatttggatgcttccaaattttctgcactccag gtgtgtggtggggctggaggtggactttatggtattgacagcatgccggatcttcgcaga aaaaaaactttgcctattgtccgagatgtggccatgaccctggctgcccggaaatctgga ctctccctggctatggtgattaggacatccctaaataatgaggaactgaaaatgcacgtc ttcaagaagaccttgcaggcactgatctaccctatgtcttctaccatcccacacaatttt gaggtctggacggctaccacacccacctactgttatgagtgtgaagggctcctgtggggc attgcaaggcaaggcatgaagtgtctggagtgtggagtgaaatgccacgaaaagtgtcag gacctgctaaacgctgactgcttgcagagagcagcagaaaagagttctaaacatggtgcc gaagacaagactcagaccattattacagcaatgaaagaaagaatgaagatcagggagaaa aaccggccagaagtatttgaagtaatccaggaaatgtttcagatttctaaagaagatttt gtgcagtttacaaaggcggccaaacagagtgtactggatgggacatctaagtggtctgca aaaataaccattacagtggtttctgcacagggtctacaggcaaaagataaaacagggtct agtgatccatatgttacagttcaagttggaaagaacaaaagaagaacaaaaaccattttt ggaaatttgaatccagtatgggatgagaagttttattttgagtgtcataactccacagat cgaatcaaagtcagagtatgggatgaagatgatgatattaaatccagagtcaagcaacat ttcaaaaaggagtcagatgattttctgggacaaacaattgtagaagtgaggaccttgagt ggagaaatggatgtctggtacaacttagagaaaaggacagataagtcagctgtatctggg gccatacgattgaaaatcaatgtggagataaaaggagaagagaaggttgctccatatcat attcaatatacatgtttacatgagaatctgttccattacttgactgaagtgaaatctaat ggtggagtgaaaatcccagaagtcaaaggggatgaagcctggaaggttttctttgatgat gcttcccaagaaatagttgatgaatttgctatgcgttatggaattgaatccatttatcaa gctatgacgcacttttcatgtctgtcttctaaatacatgtgccccggtgtccctgccgtc atgagcaccttgctggctaatataaatgctttttatgctcacacaacagtttcaacaaac atacaggtttctgcctcagatcgatttgctgctaccaactttggtagggaaaaattcata aaactactggaccagttacataactctttgaggattgatctgtcaaagtatagggaaaac tttcctgcaagcaatactgaaagactgcaagacctgaaatcaactgttgacctgttaaca agtatcaccttttttaggatgaaggttctggagctgcaaagccccccaaaagcgagcatg gtggtgaaggactgtgtaagggcttgcctggattctacatacaagtatatttttgacaac tgccatgaactctactcccagctaacagacccgagtaagaaacaggatattcctcgtgaa gatcagggaccaaccaccaagaatttggatttttggccccaacttattacactgatggtt actattattgatgaggataaaactgcctacacacctgtcctgaatcagtttcctcaagag ctgaacatgggaaaaataagtgccgaaattatgtggactctttttgctctggatatgaaa tatgcattagaagaacatgaaaatcagcggttatgcaagagcaccgattatatgaatttg catttcaaagttaaatggttttataatgaatatgtgcgtgaacttcctgccttcaaggat gctgttcctgaatactccttgtggtttgaaccttttgtcatgcaatggctagatgaaaac gaagatgtgtcaatggaattccttcatggagcactgggaagagacaaaaaagatggattc cagcagacatctgagcatgctctcttttcttgctccgtggttgatgtctttgctcagctg aatcagagctttgaaattattaagaaactggaatgccctaatcctgaagcattatctcac ttaatgagaagatttgcaaagactatcaataaagtgctgctccagtatgctgcaattgta tcaagtgatttcagttcacattgtgataaggaaaatgtgccctgtatcttgatgaacaat attcaacaattgcgggtccagctggaaaaaatgtttgaatccatgggagggaaggagcta gattctgaagctagtactattctaaaagaacttcaggttaagctcagtggggtcctggat gagctcagcgtcacttatggtgaaagtttccaggttataattgaagagtgtataaaacag atgagtttcgaactaaatcaaatgagagcaaatggaaacaccacatctaataagaacagt gcagcaatggatgcagagattgtgttaagatctcttatggattttttggacaaaacatta agtctctcagcaaaaatctgtgagaaaacagtcctaaagcgagttttaaaagagttatgg aagctagttctcaacaaaatagaaaaacaaattgttcttcctcctctgacagatcaaaca ggaccccagatgattttcattgcagctaaagatcttggacaattatccaaactgaaggag cacatgattcgagaggatgccaggggtctgacgccaagacaatgcgctataatggaggta gtcctggctaccatcaagcaatactttcatgcaggaggaaatggcctgaaaaagaatttc ttggagaaaagcccagatcttcagtctctgagatatgctctcagtctttatacccaaact actgatgccttgataaagaaattcatagatactcaaacctcacagagtcgttcctccaaa gatgccgtgggtcagatatctgttcatgtggacatcactgccaccccaggaacgggagat cataaagtcactgtaaaagtgattgctattaatgacctaaactggcagaccacagcaatg ttccgcccctttgtggaagtttgtatactgggacccaaccttggagacaagaagagaaaa caaggcacaaaaacaaaaagcaacacatggtcaccaaagtacaatgaaacatttcagttc attctcggaaaggaaaatcgaccaggggcttatgaacttcatctctcagttaaggattac tgctttgccagagaagatcgaattatcggaatgacagtcattcagctacagaacatagca gaaaagggaagctatggggcatggtatcctcttctgaaaaatatctctatggatgaaact ggtttgactatccttagaatactctctcagaggaccagtgatgatgtggctaaagaattt gtaagacttaaatctgaaacaagatctactgaagagagtgcttga

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