Homo sapiens (human): 23067
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Entry
23067 CDS
T01001
Symbol
SETD1B, IDDSELD, KMT2G, Set1B
Name
(RefSeq) SET domain containing 1B, histone lysine methyltransferase
KO
K11422
[histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:
2.1.1.354
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00310
Lysine degradation
hsa01100
Metabolic pathways
Disease
H02463
Syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
23067 (SETD1B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
23067 (SETD1B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
23067 (SETD1B)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
23067 (SETD1B)
HMT complexes
COMPASS/SET1 complex
23067 (SETD1B)
COMPASS/SET1 complex (yeast)
23067 (SETD1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SET
N-SET
RRM_1
RRM_5
Motif
Other DBs
NCBI-GeneID:
23067
NCBI-ProteinID:
NP_001340274
OMIM:
611055
HGNC:
29187
Ensembl:
ENSG00000139718
UniProt:
Q9UPS6
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:121790155..121832656
Genome browser
AA seq
1966 aa
AA seq
DB search
MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMS
SNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLR
DMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDT
KGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGS
SSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLF
SQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGT
GGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAF
GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP
GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL
SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP
PDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM
VVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAH
PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQ
VLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKF
DPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKK
ERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLP
SFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVR
RRPARPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEQESTEEEEEA
EEEEEEEVPRSQLSSSSTSSTSDKDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE
ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES
MASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVE
EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLP
LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVP
ATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS
GPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPL
PPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV
FPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP
GPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTI
LYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIR
EHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSE
QRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQN
IRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVE
SQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN
NT seq
5901 nt
NT seq
+upstream
nt +downstream
nt
atggagaacagtcaccccccccaccaccaccaccagcagcccccgccgcagcccggccct
tcgggcgagaggaggaaccaccattggagaagttacaagttgatgattgacccggctctg
aaaaaggggcatcataaactgtaccgctacgatgggcagcatttcagcctggcgatgtcc
agcaaccgcccggtggaaattgtcgaagatccccgggtcgtcgggatctggaccaaaaac
aaggagctggagctgtcggtgcccaaattcaagatcgatgagttctacgtgggcccggtg
cctccgaagcaggtgacatttgccaagctgaatgataacatccgtgaaaacttcctgagg
gacatgtgcaagaagtatggggaggtggaggaggtggagattttgtacaaccccaagacc
aagaagcacctgggcatcgccaaggtggtctttgccacggtccggggagccaaggatgcc
gttcagcacttgcacagcacttccgtcatgggcaacattatccacgtggagctggacacc
aaaggggaaacccgaatgcggttctatgaactgttggtcactggccgatacaccccccag
accctcccagtgggcgagctggacgctgtctctccaatcgtgaatgagaccctgcagctg
tcagatgccctgaagcgcctcaaggatggaggcctgtctgcaggctgtggctccggctcc
tcctctgtcacccccaatagcggtgggacacccttctcccaggacacagcttattccagc
tgccgcctggacacacccaactcctatggacagggcaccccgctcacaccgcgcctgggc
acccctttctcacaggactccagctactccagccgccagcccacaccctcatacctcttc
agccaggaccctgcagtgaccttcaaggcccggcgccacgagagcaagttcacggacgcc
tacaaccgccgccacgaacatcattatgtacacaattctcccgcggtcactgcggtggcc
ggggccacagccgctttccggggttcctcggacctcccgttcggagcagtcggcggcact
gggggcagcagcggtcccccgttcaaggctcaaccacaggattcagccacatttgcccac
actccaccacccgcccaagcaacccctgctcctggattcaagtctgctttctctccgtat
cagaccccagtggcccacttccctccacccccggaagagcccaccgccacagccgctttt
ggggcccgcgacagtggggagttccggagggcaccggcgcccccacccctgccacctgct
gagcctctggccaaggagaagccaggcacgccacccggcccgccgccccccgacaccaac
agcatggagctgggcggccggcccaccttcggctggagtcctgagccctgtgacagccct
ggcacgcccacgctggagtcgtcccctgcagggccagagaaaccccacgacagcctggac
tcgcgcatcgagatgctgctgaaggagcagcgcaccaagctgctcttcctgagggagccg
gactcggacaccgagctgcagatggagggcagccccatctcctcctcctcctcccagctc
tccccactggccccctttggcaccaactcccagccaggcttccggggccccacgcccccc
tcgtcacgcccctccagcaccggcctggaggatatcagcccaacacccctcccagactcc
gacgaggacgaggagctcgacctgggccttgggcctcggcctccacctgagccaggcccc
ccggaccctgctgggcttctgagccagacagctgaggtggccttggacctggttggagac
agaaccccgacctcagagaagatggatgagggccagcagtcctcaggcgaggacatggag
atctcggatgacgagatgccctcggcccccatcaccagcgctgactgccccaagcccatg
gtggtgaccccaggagcggcagccgtggcagccccttctgtgctagccccaaccctgccg
ctgcccccgccacctggcttccccccgctgccccccccaccaccaccacccccaccgcag
cctggcttccccatgcccccaccgctgcccccaccgccgcccccaccccctccagcccac
cctgctgtgacagtgcccccaccacccttgccagcgccgcctggagtcccgcccccaccc
atcctgccaccactgcccccctttccgccgggcctgttccctgtgatgcaggtggacatg
agccacgtgctgggtggccagtggggcggcatgcccatgtccttccagatgcaaacgcag
gtgctcagccggctgatgacgggccagggcgcctgcccctacccgcccttcatggccgct
gcggccgccgctgcctcagctgggctccagtttgtcaacctgccgccctaccggggcccc
ttctccctgagcaactccggcccaggccgcgggcagcactggccaccactgcccaagttt
gacccgtcagtgcctccaccaggctacatgccacgccaggaggacccacacaaagccacg
gtggatggcgtcctgctggtggtcctcaaagaactcaaggccatcatgaagcgtgacctg
aaccgcaagatggtggaagtggtggctttccgggcctttgacgagtggtgggacaagaag
gagcggatggccaaggcctcgctgaccccggtgaagtcgggcgagcacaaggacgaggac
aggccgaagcccaaggaccgcatcgcctcgtgcctgctggagtcatggggcaagggcgag
ggcctgggctacgagggcctgggcctgggcattgggctgcgtggggccattcgcctgccc
tccttcaaggtcaagaggaaggagccaccagacaccacctcatctggcgaccagaagcgg
ctgcggccctcgacctctgtggatgaggaagatgaagagtccgagcgagagcgagaccgg
gatatggcagacaccccctgtgagctcgccaagcgggaccccaagggcgtgggtgtgcgg
cggcggccggcgcggcctctggagctggacagtggtggggaggaggacgagaaggagtca
ttgtcggcgtcctcgtcctcatccgcgtcatcatcctcggggtcctcaaccacctcaccc
tcgtcctcggcctccgacaaggaggaggaacaggagagcaccgaggaggaagaggaggcg
gaggaggaggaggaggaggaagtccccaggagccagctctcctcctcctcaacctcatcc
acatcagataaggatgacgacgatgacgacagtgatgaccgggacgagtctgagaacgat
gacgaggacacagccctgtcagaggcgagtgagaaggacgaaggggactcggatgaagag
gagacagtgagcattgtaacctccaaggccgaagccacgtcgtccagtgagagttccgag
tcttctgagtttgagtcaagctccgagtcctcgccctcatcctcggaggatgaggaggag
gtagtggccagggaagaggaggaagaagaggaggaggaggagatggtggccgaggaaagc
atggcttctgcaggccctgaggactttgagcaggacggggaggaagcggctctggccccg
ggggcacctgcagtggactcgttgggcatggaagaggaggtggacatcgagactgaggct
gtggcccctgaggagcggccctccatgctggacgagccccccttgcctgtgggtgttgaa
gagccagcggactccagggagccgcctgaggaaccaggcctgagccaggaaggggccatg
ttgctgtctccagagccccctgccaaggaggtggaggctcgacccccattgtcccctgag
cgagctccagaacatgacctggaagtggagccggagccccctatgatgctccccttgccg
ctgcaaccaccattgccgcccccacgaccaccccggccacccagcccaccgccggagcct
gagaccacagatgcctcacacccatctgtccctccggagccccttgccgaggaccacccc
ccgcatactccaggcctctgtggcagcctggccaagtcgcagagcacagagacggtgcca
gccacaccaggcggggagcccccgctatcagggggcagcagtggcctgtccctgagctct
ccgcaagtgcccggcagccccttctcctacccagccccgtcccctagcttgagcagtggg
ggcctccctcggacacctggccgggacttcagcttcacacccaccttctccgagcccagc
gggcccttgctcctgcccgtctgcccactccccactggccgacgcgatgaacgctccggg
cccctggcctccccggtgctcctggagacgggcctgcccctccctctgccccttcccctg
cccttgcccttggcattgcccgccgtcttgcgggcccaggctcgtgcgcccaccccgctg
ccacccctgctgcccgcccccctggcctcttgccctcccccaatgaagaggaagccgggc
cggccccggcgatccccaccatctatgctctccttggatgggcccttggtccgaccacca
gcaggggccgcccttggaagggaactcctgctcctgccgggccagccacagacccccgtc
ttccccagcacccatgacccccggacggtgaccctggacttccggaacgcggggatccca
gcccctccaccaccccttcccccccagccacccccacccccacctcccccacctgtagag
cccaccaagctgccctttaaggagctagacaaccagtggccctccgaggccattcctccg
ggcccccgtgggcgcgatgaggtcactgaggaatacatggagttggccaagagccggggg
ccgtggcgccggccacctaagaagcgccatgaggacctggtgccacctgcgggctcgccc
gaactctcgccaccccagcccctcttccggccccgctcggagtttgaggagatgaccatc
ctgtatgacatctggaacggtggcatcgatgaggaggacatccgcttcctgtgtgtcacc
tacgagcgactgctacagcaggacaatggcatggactggcttaacgacacgctctgggtc
taccatccctccaccagcctctcttcagctaagaagaagaaacgggacgatggcatccgc
gagcacgtgacgggctgtgcccgcagtgagggcttctacaccatcgacaagaaggacaag
ctcagatacctcaacagcagccgtgccagcaccgatgagccccccgcagacacccagggc
atgagcatcccagcacagccccacgcctccacccgggcaggctcggagcggcgttcggag
cagcgccgcctgctgtcctccttcactggcagctgtgacagtgacctgctcaagttcaac
cagctcaagttccggaagaaaaagctcaagttctgcaagagccacattcacgactggggc
ttgttcgccatggagcccatcgcggctgacgagatggtcatcgagtacgtgggccagaat
atccgtcaggtgatcgcagacatgcgggagaagcgttatgaggacgagggcatcgggagc
agctacatgttccgggtggaccatgacaccatcatcgacgccaccaagtgcggcaacttc
gcgcgcttcatcaaccacagctgcaaccccaactgctatgccaaggtgatcacggtggag
tcacagaagaagatagtcatctactcgaagcagcacattaacgtcaatgaggagattacc
tatgactataagttccccatcgaggacgtcaagatcccctgcctctgtggctccgagaac
tgccgggggaccctcaactag
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integrated database retrieval system
