Homo sapiens (human): 23072
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Entry
23072 CDS
T01001
Symbol
HECW1, NEDL1
Name
(RefSeq) HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
KO
K12167
E3 ubiquitin-protein ligase HECW1 [EC:
2.3.2.26
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
23072 (HECW1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
23072 (HECW1)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
HECT type E3
23072 (HECW1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
HECW_N
HECW1_helix
WW
C2
Keratin_B2_2
Motif
Other DBs
NCBI-GeneID:
23072
NCBI-ProteinID:
NP_055867
OMIM:
610384
HGNC:
22195
Ensembl:
ENSG00000002746
UniProt:
Q76N89
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:43112647..43566001
Genome browser
AA seq
1606 aa
AA seq
DB search
MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAA
VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
NT seq
4821 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgcacctgtgtagtgtgaagaatctgtaccagaacaggtttttaggcctggcc
gccatggcgtctccttctagaaactcccagagccgacgccggtgcaaggagccgctccga
tacagctacaaccccgaccagttccacaacatggacctcaggggcggcccccacgatggc
gtcaccattccccgctccaccagcgacactgacctggtcacctcggacagccgctccacg
ctcatggtcagcagctcctactattccatcgggcactctcaggacctggtcatccactgg
gacataaaggaggaagtggacgctggggactggattggcatgtacctcattgatgaggtc
ttgtccgaaaactttctggactataaaaaccgtggagtcaatggttctcatcggggccag
atcatctggaagatcgatgccagctcgtactttgtggaacctgaaactaagatctgcttc
aaatactaccatggagtgagtggggccctgcgagcaaccacccccagtgtcacggtcaaa
aactcggcagctcctatttttaaaagcattggtgctgatgagaccgtccaaggacaagga
agtcggaggctgatcagcttctctctctcagatttccaagccatggggttgaagaaaggg
atgtttttcaacccagacccttatctgaagatttccattcagcctgggaaacacagcatc
ttccccgccctccctcaccatggacaggagaggagatccaagatcataggcaacaccgtg
aaccccatctggcaggccgagcaattcagttttgtgtccttgcccactgacgtgctggaa
attgaggtgaaggacaagtttgccaagagccgccccatcatcaagcgcttcttgggaaag
ctgtcgatgcccgttcaaagactcctggagagacacgccataggggatagggtggtcagc
tacacacttggccgcaggcttccaacagatcatgtgagtggacagctgcaattccgattt
gagatcacttcctccatccacccagatgatgaggagatttccctgagtaccgagcctgag
tcagcccaaattcaggacagccccatgaacaacctgatggaaagcggcagtggggaacct
cggtctgaggcaccagagtcctctgagagctggaagccagagcagctgggtgagggcagt
gtccccgatggtccagggaaccaaagcatagagctttccagaccagctgaggaagcagca
gtcatcacggaggcaggagaccagggcatggtctctgtgggacctgaaggggctggggag
ctcctggcccaggtgcaaaaggacatccagcctgcccccagtgcagaagagctggccgag
cagctggacctgggtgaggaggcatcagcactgctgctggaagacggtgaagccccagcc
agcaccaaggaggagcccttggaggaggaagcaacgacccagagccgggctggaagggaa
gaagaggagaaggagcaggaggaggagggagatgtgtctaccctggagcagggagagggc
aggctgcagctgcgggcctcggtgaagagaaaaagcaggccctgctccttgcctgtgtcc
gagctggagacggtgatcgcgtcagcctgcggggaccccgagaccccgcggacacactac
atccgcatccacaccctgctgcacagcatgccctccgcccagggcggcagcgcggcagag
gaggaggacggcgcggaggaggagtccaccctcaaggactcctcggagaaggatgggctc
agcgaggtggacacggtggccgctgacccgtctgccctggaagaggacagagaagagccc
gagggggctactccaggcacggcgcaccctggccactccgggggccacttccccagcctg
gccaatggcgcggcccaggatggcgacacgcaccccagcaccgggagcgagagcgactcc
agccccaggcaaggcggggaccacagttgcgagggctgtgacgcgtcctgctgcagcccc
tcgtgctacagctcctcgtgctacagcacgtcctgctacagcagctcgtgctacagcgcc
tcgtgctacagcccctcctgctacaacggcaacaggttcgccagccacacgcgcttctcc
tccgtggacagcgccaagatctccgagagcacggtcttctcctcgcaagacgacgaggag
gaggagaacagcgcgttcgagtcggtacccgactccatgcagagccctgagctggacccg
gagtccacgaacggcgctgggccgtggcaagacgagctggccgcccctagcgggcacgtg
gaaagaagcccggaaggtctggaatcccccgtggcaggtccaagcaatcggagagaaggt
gaatgtcctatactccataattcccagccagtaagccagcttccttccctgaggcctgaa
catcatcactacccaacaatcgatgagcctcttccaccaaactgggaagctcgaattgac
agccacgggcgggtcttttatgtggaccacgtgaaccgcacaaccacctggcagcgtccg
acggcagcagccaccccggatggcatgcggagatcggggtccatccagcagatggagcaa
ctcaacaggcggtatcaaaacattcagcgaaccattgcaacagagaggtccgaagaagat
tctggcagccaaagctgcgagcaagccccagcaggaggaggcggaggtggagggagtgac
tcagaagccgaatcttcccagtccagcttagatctaaggagagaagggtcactttctcca
gtgaactcacaaaaaatcaccttgctgctgcagtccccagcggtcaagttcatcaccaac
cccgagttcttcactgtgctacatgccaattatagtgcctaccgagtcttcaccagtagc
acctgcttaaagcacatgattctgaaagtccgacgggatgctcgcaattttgaacgctac
cagcacaaccgggacttggtgaatttcatcaacatgttcgcagacactcggctggaactg
ccccggggctgggagatcaaaacggaccagcagggaaagtcttttttcgtggaccacaac
agtcgagctaccactttcattgacccccgaatccctcttcagaacggtcgtcttcccaat
catctaactcaccgacagcacctccagaggctccgaagttacagcgctggagaggcctca
gaagtttctagaaacagaggagcctctttactggccaggccaggacacagcttagtagct
gctattcgaagccaacatcaacatgagtcattgccactggcatataatgacaagattgtg
gcatttcttcgccagccaaacatttttgaaatgctgcaagagcgtcagccaagcttagca
agaaaccacacactcagggagaaaatccattacattcggactgagggtaatcacgggctt
gagaagttgtcctgtgatgcggatctggtcattttgctgagtctctttgaagaagagatt
atgtcctacgtccccctgcaggctgccttccaccctgggtatagcttctctccccgatgt
tcaccctgttcttcacctcagaactccccaggtttacagagagccagtgcaagagcccct
tccccctaccgaagagactttgaggccaagctccgcaatttctacagaaaactggaagcc
aaaggatttggtcagggtccggggaaaattaagctcattattcgccgggatcatttgttg
gagggaaccttcaatcaggtgatggcctattcgcggaaagagctccagcgaaacaagctc
tacgtcacctttgttggagaggagggcctggactacagtggcccctcgcgggagttcttc
ttccttctgtctcaggagctcttcaacccttactatggactctttgagtactcggcaaat
gatacttacacggtgcagatcagccccatgtccgcatttgtagaaaaccatcttgagtgg
ttcaggtttagcggtcgcatcctgggtctggctctgatccatcagtaccttcttgacgct
ttcttcacgaggcccttctacaaggcactcctgagactgccctgtgatttgagtgacctg
gaatatttggatgaggaattccaccagagtttgcagtggatgaaggacaacaacatcaca
gacatcttagacctcactttcactgttaatgaagaggtttttggacaggtcacggaaagg
gagttgaagtctggaggagccaacacacaggtgacggagaaaaacaagaaggagtacatc
gagcgcatggtgaagtggcgggtggagcgcggcgtggtacagcagaccgaggcgctggtg
cgcggcttctacgaggttgtagactcgaggctggtgtccgtgtttgatgccagggagctg
gagctggtgatagctggcaccgcggaaatcgacctaaatgactggcggaataacactgag
taccggggaggttaccacgatgggcatcttgtgatccgctggttctgggctgcggtggag
cgcttcaataatgagcagaggctgagattactgcagtttgtcacgggaacatccagcgtg
ccctacgaaggcttcgcagccctccgtgggagcaatgggcttcggcgcttctgcatagag
aaatgggggaaaattacttctctccccagggcacacacatgcttcaaccgactggatctt
ccaccgtatccctcgtactccatgttgtatgaaaagctgttaacagcagtagaggaaacc
agcacctttggacttgagtga
DBGET
integrated database retrieval system
