Homo sapiens (human): 2308
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Entry
2308 CDS
T01001
Symbol
FOXO1, FKH1, FKHR, FOXO1A
Name
(RefSeq) forkhead box O1
KO
K07201
forkhead box protein O1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04068
FoxO signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04213
Longevity regulating pathway - multiple species
hsa04218
Cellular senescence
hsa04910
Insulin signaling pathway
hsa04919
Thyroid hormone signaling pathway
hsa04922
Glucagon signaling pathway
hsa04931
Insulin resistance
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa04936
Alcoholic liver disease
hsa05131
Shigellosis
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05215
Prostate cancer
Network
nt06240
Transcription (cancer)
Element
N00141
PAX3-FOXO1 fusion to transcriptional activation
Disease
H00037
Rhabdomyosarcoma
H02434
Diffuse large B-cell lymphoma, not otherwise specified
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
2308 (FOXO1)
04152 AMPK signaling pathway
2308 (FOXO1)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
2308 (FOXO1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
2308 (FOXO1)
04922 Glucagon signaling pathway
2308 (FOXO1)
04919 Thyroid hormone signaling pathway
2308 (FOXO1)
09149 Aging
04211 Longevity regulating pathway
2308 (FOXO1)
04213 Longevity regulating pathway - multiple species
2308 (FOXO1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
2308 (FOXO1)
05202 Transcriptional misregulation in cancer
2308 (FOXO1)
09162 Cancer: specific types
05215 Prostate cancer
2308 (FOXO1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
2308 (FOXO1)
09171 Infectious disease: bacterial
05131 Shigellosis
2308 (FOXO1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
2308 (FOXO1)
04931 Insulin resistance
2308 (FOXO1)
04933 AGE-RAGE signaling pathway in diabetic complications
2308 (FOXO1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
2308 (FOXO1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Fork head/winged helix other regulators
2308 (FOXO1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FOXO_KIX_bdg
Forkhead
FOXO-TAD
Motif
Other DBs
NCBI-GeneID:
2308
NCBI-ProteinID:
NP_002006
OMIM:
136533
HGNC:
3819
Ensembl:
ENSG00000150907
UniProt:
Q12778
Structure
PDB
LinkDB
All DBs
Position
13:complement(40555667..40666641)
Genome browser
AA seq
655 aa
AA seq
DB search
MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPS
ASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHP
APPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKR
LTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLN
PEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPG
SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP
SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN
YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPV
DPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLP
HTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPS
DLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atggccgaggcgcctcaggtggtggagatcgacccggacttcgagccgctgccccggccg
cgctcgtgcacctggccgctgcccaggccggagtttagccagtccaactcggccacctcc
agcccggcgccgtcgggcagcgcggctgccaaccccgacgccgcggcgggcctgccctcg
gcctcggctgccgctgtcagcgccgacttcatgagcaacctgagcttgctggaggagagc
gaggacttcccgcaggcgcccggctccgtggcggcggcggtggcggcggcggccgccgcg
gccgccaccggggggctgtgcggggacttccagggcccggaggcgggctgcctgcaccca
gcgccaccgcagcccccgccgcccgggccgctgtcgcagcacccgccggtgccccccgcc
gccgctgggccgctcgcggggcagccgcgcaagagcagctcgtcccgccgcaacgcgtgg
ggcaacctgtcctacgccgacctcatcaccaaggccatcgagagctcggcggagaagcgg
ctcacgctgtcgcagatctacgagtggatggtcaagagcgtgccctacttcaaggataag
ggtgacagcaacagctcggcgggctggaagaattcaattcgtcataatctgtccctacac
agcaagttcattcgtgtgcagaatgaaggaactggaaaaagttcttggtggatgctcaat
ccagagggtggcaagagcgggaaatctcctaggagaagagctgcatccatggacaacaac
agtaaatttgctaagagccgaagccgagctgccaagaagaaagcatctctccagtctggc
caggagggtgctggggacagccctggatcacagttttccaaatggcctgcaagccctggc
tctcacagcaatgatgactttgataactggagtacatttcgccctcgaactagctcaaat
gctagtactattagtgggagactctcacccattatgaccgaacaggatgatcttggagaa
ggggatgtgcattctatggtgtacccgccatctgccgcaaagatggcctctactttaccc
agtctgtctgagataagcaatcccgaaaacatggaaaatcttttggataatctcaacctt
ctctcatcaccaacatcattaactgtttcgacccagtcctcacctggcaccatgatgcag
cagacgccgtgctactcgtttgcgccaccaaacaccagtttgaattcacccagcccaaac
taccaaaaatatacatatggccaatccagcatgagccctttgccccagatgcctatacaa
acacttcaggacaataagtcgagttatggaggtatgagtcagtataactgtgcgcctgga
ctcttgaaggagttgctgacttctgactctcctccccataatgacattatgacaccagtt
gatcctggggtagcccagcccaacagccgggttctgggccagaacgtcatgatgggccct
aattcggtcatgtcaacctatggcagccaggcatctcataacaaaatgatgaatcccagc
tcccatacccaccctggacatgctcagcagacatctgcagttaacgggcgtcccctgccc
cacacggtaagcaccatgccccacacctcgggtatgaaccgcctgacccaagtgaagaca
cctgtacaagtgcctctgccccaccccatgcagatgagtgccctggggggctactcctcc
gtgagcagctgcaatggctatggcagaatgggccttctccaccaggagaagctcccaagt
gacttggatggcatgttcattgagcgcttagactgtgacatggaatccatcattcggaat
gacctcatggatggagatacattggattttaactttgacaatgtgttgcccaaccaaagc
ttcccacacagtgtcaagacaacgacacatagctgggtgtcaggctga
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