Homo sapiens (human): 2308
Help
Entry
2308 CDS
T01001
Symbol
FOXO1, FKH1, FKHR, FOXO1A
Name
(RefSeq) forkhead box protein O1
KO
K07201
forkhead box protein O1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04068
FoxO signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04213
Longevity regulating pathway - multiple species
hsa04218
Cellular senescence
hsa04517
IgSF CAM signaling
hsa04910
Insulin signaling pathway
hsa04919
Thyroid hormone signaling pathway
hsa04922
Glucagon signaling pathway
hsa04931
Insulin resistance
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa04936
Alcoholic liver disease
hsa05131
Shigellosis
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05215
Prostate cancer
Network
nt06240
Transcription (cancer)
Element
N00141
PAX3-FOXO1 fusion to transcriptional activation
Disease
H00037
Rhabdomyosarcoma
H02434
Diffuse large B-cell lymphoma, not otherwise specified
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
2308 (FOXO1)
04152 AMPK signaling pathway
2308 (FOXO1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
2308 (FOXO1)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
2308 (FOXO1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
2308 (FOXO1)
04922 Glucagon signaling pathway
2308 (FOXO1)
04919 Thyroid hormone signaling pathway
2308 (FOXO1)
09149 Aging
04211 Longevity regulating pathway
2308 (FOXO1)
04213 Longevity regulating pathway - multiple species
2308 (FOXO1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
2308 (FOXO1)
05202 Transcriptional misregulation in cancer
2308 (FOXO1)
09162 Cancer: specific types
05215 Prostate cancer
2308 (FOXO1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
2308 (FOXO1)
09171 Infectious disease: bacterial
05131 Shigellosis
2308 (FOXO1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
2308 (FOXO1)
04931 Insulin resistance
2308 (FOXO1)
04933 AGE-RAGE signaling pathway in diabetic complications
2308 (FOXO1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
2308 (FOXO1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Fork head/winged helix other regulators
2308 (FOXO1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FOXO_KIX_bdg
Forkhead
FOXO-TAD
Motif
Other DBs
NCBI-GeneID:
2308
NCBI-ProteinID:
NP_002006
OMIM:
136533
HGNC:
3819
Ensembl:
ENSP00000368880.4
UniProt:
Q12778
Structure
PDB
PDBj
LinkDB
All DBs
Position
13:complement(40555667..40666641)
Genome browser
AA seq
655 aa
AA seq
DB search
MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPS
ASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHP
APPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKR
LTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLN
PEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPG
SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP
SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN
YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPV
DPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLP
HTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPS
DLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atggccgaggcgcctcaggtggtggagatcgacccggacttcgagccgctgccccggccg
cgctcgtgcacctggccgctgcccaggccggagtttagccagtccaactcggccacctcc
agcccggcgccgtcgggcagcgcggctgccaaccccgacgccgcggcgggcctgccctcg
gcctcggctgccgctgtcagcgccgacttcatgagcaacctgagcttgctggaggagagc
gaggacttcccgcaggcgcccggctccgtggcggcggcggtggcggcggcggccgccgcg
gccgccaccggggggctgtgcggggacttccagggcccggaggcgggctgcctgcaccca
gcgccaccgcagcccccgccgcccgggccgctgtcgcagcacccgccggtgccccccgcc
gccgctgggccgctcgcggggcagccgcgcaagagcagctcgtcccgccgcaacgcgtgg
ggcaacctgtcctacgccgacctcatcaccaaggccatcgagagctcggcggagaagcgg
ctcacgctgtcgcagatctacgagtggatggtcaagagcgtgccctacttcaaggataag
ggtgacagcaacagctcggcgggctggaagaattcaattcgtcataatctgtccctacac
agcaagttcattcgtgtgcagaatgaaggaactggaaaaagttcttggtggatgctcaat
ccagagggtggcaagagcgggaaatctcctaggagaagagctgcatccatggacaacaac
agtaaatttgctaagagccgaagccgagctgccaagaagaaagcatctctccagtctggc
caggagggtgctggggacagccctggatcacagttttccaaatggcctgcaagccctggc
tctcacagcaatgatgactttgataactggagtacatttcgccctcgaactagctcaaat
gctagtactattagtgggagactctcacccattatgaccgaacaggatgatcttggagaa
ggggatgtgcattctatggtgtacccgccatctgccgcaaagatggcctctactttaccc
agtctgtctgagataagcaatcccgaaaacatggaaaatcttttggataatctcaacctt
ctctcatcaccaacatcattaactgtttcgacccagtcctcacctggcaccatgatgcag
cagacgccgtgctactcgtttgcgccaccaaacaccagtttgaattcacccagcccaaac
taccaaaaatatacatatggccaatccagcatgagccctttgccccagatgcctatacaa
acacttcaggacaataagtcgagttatggaggtatgagtcagtataactgtgcgcctgga
ctcttgaaggagttgctgacttctgactctcctccccataatgacattatgacaccagtt
gatcctggggtagcccagcccaacagccgggttctgggccagaacgtcatgatgggccct
aattcggtcatgtcaacctatggcagccaggcatctcataacaaaatgatgaatcccagc
tcccatacccaccctggacatgctcagcagacatctgcagttaacgggcgtcccctgccc
cacacggtaagcaccatgccccacacctcgggtatgaaccgcctgacccaagtgaagaca
cctgtacaagtgcctctgccccaccccatgcagatgagtgccctggggggctactcctcc
gtgagcagctgcaatggctatggcagaatgggccttctccaccaggagaagctcccaagt
gacttggatggcatgttcattgagcgcttagactgtgacatggaatccatcattcggaat
gacctcatggatggagatacattggattttaactttgacaatgtgttgcccaaccaaagc
ttcccacacagtgtcaagacaacgacacatagctgggtgtcaggctga
Homo sapiens (human): 2309
Help
Entry
2309 CDS
T01001
Symbol
FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A
Name
(RefSeq) forkhead box protein O3 isoform 1
KO
K09408
forkhead box protein O3
Organism
hsa
Homo sapiens (human)
Pathway
hsa01521
EGFR tyrosine kinase inhibitor resistance
hsa04062
Chemokine signaling pathway
hsa04068
FoxO signaling pathway
hsa04137
Mitophagy - animal
hsa04151
PI3K-Akt signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04213
Longevity regulating pathway - multiple species
hsa04218
Cellular senescence
hsa04722
Neurotrophin signaling pathway
hsa04917
Prolactin signaling pathway
hsa04936
Alcoholic liver disease
hsa05131
Shigellosis
hsa05208
Chemical carcinogenesis - reactive oxygen species
hsa05213
Endometrial cancer
hsa05223
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
2309 (FOXO3)
04151 PI3K-Akt signaling pathway
2309 (FOXO3)
04152 AMPK signaling pathway
2309 (FOXO3)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
2309 (FOXO3)
09143 Cell growth and death
04218 Cellular senescence
2309 (FOXO3)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
2309 (FOXO3)
09152 Endocrine system
04917 Prolactin signaling pathway
2309 (FOXO3)
09156 Nervous system
04722 Neurotrophin signaling pathway
2309 (FOXO3)
09149 Aging
04211 Longevity regulating pathway
2309 (FOXO3)
04213 Longevity regulating pathway - multiple species
2309 (FOXO3)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
2309 (FOXO3)
09162 Cancer: specific types
05213 Endometrial cancer
2309 (FOXO3)
05223 Non-small cell lung cancer
2309 (FOXO3)
09171 Infectious disease: bacterial
05131 Shigellosis
2309 (FOXO3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
2309 (FOXO3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
2309 (FOXO3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
2309 (FOXO3)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Fork head/winged helix other regulators
2309 (FOXO3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FOXO_KIX_bdg
Forkhead
FOXO-TAD
NicX
Motif
Other DBs
NCBI-GeneID:
2309
NCBI-ProteinID:
NP_001446
OMIM:
602681
HGNC:
3821
Ensembl:
ENSP00000385824.1
UniProt:
O43524
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:108559825..108684774
Genome browser
AA seq
673 aa
AA seq
DB search
MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS
GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL
SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG
GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS
DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK
PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG
SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS
HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT
QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP
VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT
GAKQASSQSWVPG
NT seq
2022 nt
NT seq
+upstream
nt +downstream
nt
atggcagaggcaccggcttccccggccccgctctctccgctcgaagtggagctggacccg
gagttcgagccccagagccgtccgcgatcctgtacgtggcccctgcaaaggccggagctc
caagcgagccctgccaagccctcgggggagacggccgccgactccatgatccccgaggag
gaggacgatgaagacgacgaggacggcgggggacgggccggctcggccatggcgatcggc
ggcggcggcgggagcggcacgctgggctccgggctgctccttgaggactcggcccgggtg
ctggcacccggagggcaagaccccgggtctgggccagccaccgcggcgggcgggctgagc
gggggtacacaggcgctgctgcagcctcagcaaccgctgccaccgccgcagccgggggcg
gctgggggctccgggcagccgaggaaatgttcgtcgcggcggaacgcctggggaaacctg
tcctacgcggacctgatcacccgcgccatcgagagctccccggacaaacggctcactctg
tcccagatctacgagtggatggtgcgttgcgtgccctacttcaaggataagggcgacagc
aacagctctgccggctggaagaactccatccggcacaacctgtcactgcatagtcgattc
atgcgggtccagaatgagggaactggcaagagctcttggtggatcatcaaccctgatggg
gggaagagcggaaaagccccccggcggcgggctgtctccatggacaatagcaacaagtat
accaagagccgtggccgcgcagccaagaagaaggcagccctgcagacagcccccgaatca
gctgacgacagtccctcccagctctccaagtggcctggcagccccacgtcacgcagcagt
gatgagctggatgcgtggacggacttccgttcacgcaccaattctaacgccagcacagtc
agtggccgcctgtcgcccatcatggcaagcacagagttggatgaagtccaggacgatgat
gcgcctctctcgcccatgctctacagcagctcagccagcctgtcaccttcagtaagcaag
ccgtgcacggtggaactgccacggctgactgatatggcaggcaccatgaatctgaatgat
gggctgactgaaaacctcatggacgacctgctggataacatcacgctcccgccatcccag
ccatcgcccactgggggactcatgcagcggagctctagcttcccgtataccaccaagggc
tcgggcctgggctccccaaccagctcctttaacagcacggtgttcggaccttcatctctg
aactccctacgccagtctcccatgcagaccatccaagagaacaagccagctaccttctct
tccatgtcacactatggtaaccagacactccaggacctgctcacttcggactcacttagc
cacagcgatgtcatgatgacacagtcggaccccttgatgtctcaggccagcaccgctgtg
tctgcccagaattcccgccggaacgtgatgcttcgcaatgatccgatgatgtcctttgct
gcccagcctaaccagggaagtttggtcaatcagaacttgctccaccaccagcaccaaacc
cagggcgctcttggtggcagccgtgccttgtcgaattctgtcagcaacatgggcttgagt
gagtccagcagccttgggtcagccaaacaccagcagcagtctcctgtcagccagtctatg
caaaccctctcggactctctctcaggctcctccttgtactcaactagtgcaaacctgccc
gtcatgggccatgagaagttccccagcgacttggacctggacatgttcaatgggagcttg
gaatgtgacatggagtccattatccgtagtgaactcatggatgctgatgggttggatttt
aactttgattccctcatctccacacagaatgttgttggtttgaacgtggggaacttcact
ggtgctaagcaggcctcatctcagagctgggtgccaggctga
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integrated database retrieval system
