Homo sapiens (human): 2313
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Entry
2313 CDS
T01001
Symbol
FLI1, BDPLT21, EWSR2, SIC-1
Name
(RefSeq) Fli-1 proto-oncogene, ETS transcription factor
KO
K09436
friend leukemia integration 1 transcription factor
Organism
hsa
Homo sapiens (human)
Pathway
hsa05202
Transcriptional misregulation in cancer
Network
nt06240
Transcription
Element
N00133
EWSR1-FLI1 fusion to transcriptional activation
N00134
EWSR1-FLI1 fusion to transcriptional repression
Disease
H00035
Ewing sarcoma
H01235
Bleeding disorder platelet-type
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
2313 (FLI1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
2313 (FLI1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Tryptophan clusters Ets-type
2313 (FLI1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ets
SAM_PNT
Motif
Other DBs
NCBI-GeneID:
2313
NCBI-ProteinID:
NP_002008
OMIM:
193067
HGNC:
3749
Ensembl:
ENSG00000151702
Vega:
OTTHUMG00000165792
Pharos:
Q01543
(Tbio)
UniProt:
Q01543
A0A024R3M5
Structure
PDB
LinkDB
All DBs
Position
11:128685263..128813267
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AA seq
452 aa
AA seq
DB search
MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN
ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT
LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK
SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI
TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF
DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS
QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggacgggactattaaggaggctctgtcggtggtgagcgacgaccagtccctctttgac
tcagcgtacggagcggcagcccatctccccaaggccgacatgactgcctcggggagtcct
gactacgggcagccccacaagatcaaccccctcccaccacagcaggagtggatcaatcag
ccagtgagggtcaacgtcaagcgggagtatgaccacatgaatggatccagggagtctccg
gtggactgcagcgttagcaaatgcagcaagctggtgggcggaggcgagtccaaccccatg
aactacaacagctatatggacgagaagaatggcccccctcctcccaacatgaccaccaac
gagaggagagtcatcgtccccgcagaccccacactgtggacacaggagcatgtgaggcaa
tggctggagtgggccataaaggagtacagcttgatggagatcgacacatcctttttccag
aacatggatggcaaggaactgtgtaaaatgaacaaggaggacttcctccgcgccaccacc
ctctacaacacggaagtgctgttgtcacacctcagttacctcagggaaagttcactgctg
gcctataatacaacctcccacaccgaccaatcctcacgattgagtgtcaaagaagaccct
tcttatgactcagtcagaagaggagcttggggcaataacatgaattctggcctcaacaaa
agtcctccccttggaggggcacaaacgatcagtaagaatacagagcaacggccccagcca
gatccgtatcagatcctgggcccgaccagcagtcgcctagccaaccctggaagcgggcag
atccagctgtggcaattcctcctggagctgctctccgacagcgccaacgccagctgtatc
acctgggaggggaccaacggggagttcaaaatgacggaccccgatgaggtggccaggcgc
tggggcgagcggaaaagcaagcccaacatgaattacgacaagctgagccgggccctccgt
tattactatgataaaaacattatgaccaaagtgcacggcaaaagatatgcttacaaattt
gacttccacggcattgcccaggctctgcagccacatccgaccgagtcgtccatgtacaag
tacccttctgacatctcctacatgccttcctaccatgcccaccagcagaaggtgaacttt
gtccctccccatccatcctccatgcctgtcacttcctccagcttctttggagccgcatca
caatactggacctcccccacggggggaatctaccccaaccccaacgtcccccgccatcct
aacacccacgtgccttcacacttaggcagctactactag
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