Homo sapiens (human): 23152
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Entry
23152 CDS
T01001
Gene name
CIC, MRD45
Definition
(RefSeq) capicua transcriptional repressor
KO
K20225
capicua transcriptional repressor
Organism
hsa
Homo sapiens (human)
Pathway
hsa05017
Spinocerebellar ataxia
Disease
H00773
Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
23152 (CIC)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
23152 (CIC)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
HMG SOX
23152 (CIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HMG_box
HMG_box_2
Motif
Other DBs
NCBI-GeneID:
23152
NCBI-ProteinID:
NP_055940
OMIM:
612082
HGNC:
14214
Ensembl:
ENSG00000079432
Vega:
OTTHUMG00000182794
Pharos:
Q96RK0
(Tbio)
UniProt:
Q96RK0
LinkDB
All DBs
Structure
PDB:
4J2J
6JRP
4J2L
Thumbnails
Position
19q13.2
AA seq
1608 aa
AA seq
DB search
MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQ
PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESG
KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKE
RDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYA
LGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSM
SETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV
HSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLP
TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS
GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPA
SSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRR
KRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAP
AAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG
SPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF
IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP
APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA
QSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP
SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS
PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL
PPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA
PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP
GPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAK
GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPE
RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLA
TSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFD
RTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADI
FPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT
SPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR
NT seq
4827 nt
NT seq
+upstream
nt +downstream
nt
atgtattcggcccacaggcccctgatgcccgcgtccagcgcggcctcccgtggcctcggc
atgttcgtgtggacgaatgtggaacctcgctctgtggctgtgttcccttggcactcctta
gtccccttcctggcacccagccagcctgacccctccgtgcagccgagcgaggcccagcaa
cctgccagccacccagtggcctccaaccagagcaaagaacctgctgagtcggcagctgtt
gctcatgaacggccaccaggtgggacagggagtgctgaccctgagcggccccctggagcc
acatgccctgagagcccaggacccggacccccacaccctttgggggtggtggaatctggt
aagggtccgcctcccaccacggaggaggaggcctccggccccccaggagagccccggctg
gacagtgagacagagagtgaccatgatgatgccttcctctccatcatgtctcctgagatc
cagttgcctctaccgcccggaaaacgtcggacccagtccctcagtgccctacccaaggaa
cgggactcatcttctgagaaggatggacgcagccccaacaagcgggagaaggaccacatc
cggcggcccatgaatgccttcatgatcttcagcaagcggcaccgggccctggtccaccag
cgtcatcccaaccaggacaaccggaccgtcagcaagatcctgggcgagtggtggtatgcc
ctggggcccaaggagaagcagaagtaccacgacctggccttccaggtgaaggaggcccac
ttcaaggcccacccagattggaagtggtgcaacaaggaccgaaagaagtccagctcagag
gccaagcccacgagcctggggctggcaggagggcacaaggagacgcgggagcggagcatg
tcggagacgggcactgctgctgcccctggggtgtcctctgagctcctgtccgttgcagcc
cagacactcctgagctcagacaccaaggctccggggagcagctcctgtggggcagaacgg
ctacacacagttgggggacctggctcagcccggccccgagctttctcccacagcggggta
cacagcctggacggcggagaagtagacagtcaggcgctacaggaactgacgcagatggtg
tctggccctgcatcgtactctggcccaaagccttctacccagtatggagctccaggaccc
tttgcagcccctggtgagggaggtgccttggcggccactgggcggcccccgctgctgccc
acccgagcttctcgttctcagcgtgcggccagtgaggacatgacgagtgatgaggagcgc
atggtcatctgtgaggaggaaggggatgatgatgtcattgctgacgatggcttcggcacc
actgacattgatctcaagtgcaaggagcgggtgaccgacagcgagagtggggacagctct
ggggaggacccagagggcaacaagggctttggtcggaaggtgttttcacctgtgatccgt
tcctcctttacccactgccgccccccactggaccctgagcccccagggcccccggatcct
cctgtagcctttggcaaaggctatggttccgccccatcctcctctgcgtcctcgcctgct
tcctcctcagcctcggcagccacctccttctcactgggctcaggaaccttcaaggcccag
gagtctggtcagggcagcacagcgggccccctacggcccccaccccctggggctgggggt
ccagcgacaccttccaaggcaacccggttcctcccaatggatcctgccaccttccggcgc
aagagacccgaaagtgtgggtggcctggagccaccaggcccctcagtcatcgcggcccct
cccagcggaggaggaaacatcctgcagacactggtgctgcccccaaacaaggaggagcaa
gagggcggcggagccagagtgccctccgcccccgccccatcactggcctatggggcccca
gcagctcccctgtcccgtcctgccgccaccatggtcaccaatgtggtgcggcctgtcagc
agcactcctgtgcccatcgcctctaagcccttccccacctctggccgggctgaggcgtct
ccaaatgacacagcaggtgccaggactgaaatgggcactgggtctcgggtgcctgggggc
tccccgctgggtgtcagcttagtgtattcggacaagaagtcggcagcagccacctcacca
gccccacacttggtggctggacccctgctgggcactgtggggaaggcgcctgccactgtc
actaacctactggtgggcaccccggggtatggggcccctgcgccccctgctgtccagttc
attgcccagggggcccctggtggtgggaccactgcgggctcaggagcaggtgctgggagt
ggccccaatgggccagtacccctgggcatcctgcaaccaggtgccctgggcaaggctggg
ggaatcacccaggtacagtacatcctgcccacgctgccccagcagcttcaggtggcacct
gccccagcaccagcccctgggaccaaggcagcggctcccagcggccctgcacccaccacc
agcatccgtttcaccctcccaccgggcacttccaccaacggcaaagtcctggctgccact
gcacccactcctggcatccccatcctgcagtctgtaccctccgccccaccccccaaagcc
cagtcagtttctcccgtgcaggccccgcccccgggtggctcagcccagctgctgcctggg
aaggtcctagtgcctctggccgcccctagcatgtcagtgcggggtggaggggccggccag
ccactgccactggtgagcccgcccttctcagtacctgtgcagaatggtgcccagcccccc
agcaagatcatccagctgaccccggtgcctgtgagcacacccagcggcctggtgccgccc
ctgagcccagccacactccctggacccacctctcagcctcagaaggtcctgttgccctcc
tccaccagaatcacctatgtgcagtcagcgggcgggcacgcgctgcccctgggtaccagc
cctgcgtccagccaggctggaacagtcacctcgtacgggcccacgagctctgtagctcta
ggcttcacctcgctggggcccagcggccccgccttcgtgcagcccctgctctcagcaggc
caagccccactgctggctcccggtcaggtgggcgtgtcacctgtgcccagtccccagctg
ccgcctgcctgtgcagcccccggaggtcctgtcataacagcattttactctggcagccct
gcacccacctcctcagcacccctggcccagccatcccaggcccccccaagcctggtctac
actgtggccaccagcacaaccccacctgcagccaccattctgcccaagggcccgccagcc
cctgccactgccaccccagccccgactagccctttccccagcgccacagcaggttccatg
acctacagcttagtggcccccaaggcccagcggcccagcccgaaggccccccagaaagtg
aaggcagccatcgccagcattcccgtggggtcctttgaggcaggtgcctctgggcggcct
ggccctgcaccccggcagcctctggagcctggcccagtccgagagccaactgccccagag
tctgagcttgaggggcagcccacaccaccagcccctccacccctgccagagacctggact
cccacggcccggagcagccccccactgcccccacctgctgaggagcggaccagcgccaag
ggccctgagaccatggccagcaaattccccagctcatcttcagactggcgcgtccctggg
cagggcctggagaatcgtggggagcctcccactcctcccagcccggccccagctccagct
gtagcccctggtggcagcagcgagagcagcagtgggcgggcagccggggacaccccggag
cgcaaggaggcggctggtactggcaagaaggtgaaggtgcggcccccgcccctgaagaag
acctttgactctgtggacaacagggtcctgtcagaagtggacttcgaagagcgctttgct
gagttgcctgagtttcggcctgaggaggtgctgccctcccccaccctgcagtctctggcc
acctcaccccgggccatcctgggctcttaccgcaagaagaggaagaactccacggacctg
gattcagcacccgaggaccccacctcgcccaagcgcaagatgagaagacgctccagctgc
agctcggagcccaacacccccaagagtgccaagtgcgagggggacatcttcacctttgac
cgtacaggtacagaagccgaggacgtgcttggggagctagagtatgacaaggtgccatac
tcctccctgcggcgcaccctggaccagcgccgggccctggtcatgcagctctttcaggac
catggcttcttcccgtcagcccaggccacagccgccttccaggcccgctatgcagacatc
tttccctccaaggtttgtctgcagttgaagatccgtgaggtgcgccagaagatcatgcag
gctgccactcccacggagcagccccctggagctgaggctcctctccctgtaccgcccccc
actggcaccgctgctgcccctgcccccactcccagccccgcagggggccctgaccccacc
tcacccagctcggactctggcacggcccaggctgccccgccactgcctccacccccagag
tcggggcctggacagcctggctgggagggggctccccagccctcccccccacccccaggt
ccctccacagctgccacaggcaggtga
DBGET
integrated database retrieval system
