Homo sapiens (human): 23305
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Entry
23305 CDS
T01001
Symbol
ACSL6, ACS2, FACL6, LACS_6, LACS2, LACS5
Name
(RefSeq) acyl-CoA synthetase long chain family member 6
KO
K01897
long-chain-fatty-acid---CoA ligase [EC:
6.2.1.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00061
Fatty acid biosynthesis
hsa00071
Fatty acid degradation
hsa01100
Metabolic pathways
hsa01212
Fatty acid metabolism
hsa03320
PPAR signaling pathway
hsa04146
Peroxisome
hsa04216
Ferroptosis
hsa04714
Thermogenesis
hsa04920
Adipocytokine signaling pathway
Module
hsa_M00086
beta-Oxidation, acyl-CoA synthesis
Network
nt06020
beta-Oxidation in mitochondria
Element
N00765
beta-Oxidation, acyl-CoA synthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
23305 (ACSL6)
00071 Fatty acid degradation
23305 (ACSL6)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
23305 (ACSL6)
09143 Cell growth and death
04216 Ferroptosis
23305 (ACSL6)
09150 Organismal Systems
09152 Endocrine system
04920 Adipocytokine signaling pathway
23305 (ACSL6)
03320 PPAR signaling pathway
23305 (ACSL6)
09159 Environmental adaptation
04714 Thermogenesis
23305 (ACSL6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
hsa01004
]
23305 (ACSL6)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
23305 (ACSL6)
Enzymes [BR:
hsa01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.3 long-chain-fatty-acid---CoA ligase
23305 (ACSL6)
Lipid biosynthesis proteins [BR:
hsa01004
]
Acyl-CoA ligase
Long/very long chain acyl-CoA ligase
23305 (ACSL6)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of breast milk
23305 (ACSL6)
Exosomal proteins of breast cancer cells
23305 (ACSL6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
AMP-binding_C
Motif
Other DBs
NCBI-GeneID:
23305
NCBI-ProteinID:
NP_001192177
OMIM:
604443
HGNC:
16496
Ensembl:
ENSG00000164398
UniProt:
Q9UKU0
B2RB13
LinkDB
All DBs
Position
5:complement(131949973..132012213)
Genome browser
AA seq
697 aa
AA seq
DB search
MQTQEILRILRLPELGDLGQFFRSLSATTLVSMGALAAILAYWFTHRPKALQPPCNLLMQ
SEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQW
LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT
LGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQK
CGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGF
LKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP
TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKI
QASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHV
GAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGD
IGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGI
VVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHS
DMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSISM
NT seq
2094 nt
NT seq
+upstream
nt +downstream
nt
atgcagacacaggagatcctgaggatactgcgactgcctgagctaggtgacttgggacag
tttttccgcagcctctcggccaccaccctcgtgagtatgggtgccctggctgccatcctt
gcctactggttcactcaccggccaaaggccttgcagccgccatgcaacctcctgatgcag
tcagaagaagtagaggacagtggcggggcacggcgatctgtgattgggtctggccctcag
ctacttacccactactatgatgatgcccggaccatgtaccaggtgttccgccgtgggctt
agcatctcagggaatgggccctgtcttggtttcaggaagcctaagcagccttaccagtgg
ctgtcctaccaggaggtggccgacagggctgaatttctggggtccggacttctccagcac
aattgtaaagcatgcactgatcagtttattggtgtttttgcacaaaatcggccagagtgg
atcattgtggagctggcctgctacacatattccatggtggtggtcccgctctatgacacc
ctgggccctggggctatccgctacatcatcaatacagcggacatcagcaccgtgattgtg
gacaaacctcagaaggctgtgcttctgctagagcatgtggagaggaaggagactccaggc
ctcaagctgatcatcctcatggacccattcgaagaagccctgaaagagagagggcagaag
tgcggggtggtcattaagtccatgcaggccgtggaggactgtggccaagagaatcaccag
gctcctgtgcccccgcagcctgatgacctctccattgtgtgtttcacaagcggcacgaca
gggaacccaaaaggtgcgatgctcacccatgggaacgtggtggctgatttctcaggcttt
ctgaaagtgacagagagtcagtgggctcccacttgtgcggatgtgcacatttcctatttg
cctttagcacacatgtttgagcgaatggtgcagtctgtcgtctattgccacggagggcgt
gttggcttcttccagggagatatccgccttctctcagatgacatgaaggctctatgcccc
accatcttccctgtggtcccacgactgctgaaccggatgtacgacaagatcttcagccag
gcaaacacaccattaaagcgctggctcctggagtttgcagcaaagcgtaagcaagccgag
gtccggagtggaatcatcaggaatgatagtatctgggatgaactcttctttaataagatt
caggccagtcttggtgggtgtgtgcggatgattgttactggagcagccccagcatcacca
acagttctgggatttctccgggcagctctagggtgccaggtttatgaaggttatggccaa
actgagtgcacagctggatgtaccttcaccactcctggcgactggacctcagggcacgta
ggggcgccacttccctgcaatcatatcaagctcgttgatgttgaggaactgaactactgg
gcctgcaaaggagagggagagatatgtgtgagaggaccaaatgtgttcaaaggctacttg
aaagatccagacaggacgaaggaggccctggacagcgatggctggcttcacactggagac
atcggaaaatggctgccggcaggaactcttaaaattattgatcggaaaaagcatatattt
aaacttgctcagggagaatatgttgcacccgagaagattgagaacatctacatccggagc
caacctgtggcgcaaatctatgtccatggggacagcttaaaggcctttttggtaggcatt
gttgtgcctgaccctgaagttatgccctcctgggcccagaagagaggaattgaaggaaca
tatgcagatctctgcacaaataaggatctgaagaaagccattttggaagatatggtgagg
ttaggaaaagaaagtggactccattcttttgagcaggttaaagccattcacatccattct
gacatgttctcagttcaaaatggcttgctgacaccaacactaaaagctaagagacctgag
ctgagagagtacttcaaaaaacaaatagaagagctttactcaatctccatgtga
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