Homo sapiens (human): 23381
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Entry
23381 CDS
T01001
Symbol
SMG5, EST1B, LPTS-RP1, LPTSRP1, SMG-5
Name
(RefSeq) SMG5 nonsense mediated mRNA decay factor
KO
K11125
protein SMG5
Organism
hsa
Homo sapiens (human)
Pathway
hsa03015
mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03015 mRNA surveillance pathway
23381 (SMG5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
23381 (SMG5)
03032 DNA replication proteins [BR:
hsa03032
]
23381 (SMG5)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Surveillance factors
Other surveillance factors
23381 (SMG5)
mRNA cycle factors
Common to processing body (P body) and stress granule
23381 (SMG5)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Termination Factors
Telomerase complex (animals)
23381 (SMG5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EST1_DNA_bind
EST1
PIN_4
SPAR
Motif
Other DBs
NCBI-GeneID:
23381
NCBI-ProteinID:
NP_056142
OMIM:
610962
HGNC:
24644
Ensembl:
ENSG00000198952
UniProt:
Q9UPR3
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(156249224..156291516)
Genome browser
AA seq
1016 aa
AA seq
DB search
MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR
ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG
FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD
LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ
SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP
KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI
ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE
PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES
DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE
PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT
SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV
FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP
DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ
GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL
EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP
GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG
AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG
NT seq
3051 nt
NT seq
+upstream
nt +downstream
nt
atgagccaaggcccccccacaggggagagcagcgagcccgaagcaaaagtcctccacact
aagcggctttaccgggctgtggtggaggctgtgcatcgacttgacctcatcctttgcaac
aaaactgcttatcaagaagtattcaaaccagaaaacattagcctgaggaacaagctgcgt
gagctctgcgtcaagcttatgttcctgcacccagtggactatgggagaaaggctgaggag
ctgctgtggagaaaggtatactatgaagttatccagcttatcaagactaacaaaaagcac
atccacagccggagcactttggaatgtgcctacaggacgcacctggttgctggtattggc
ttctaccagcatctccttctctatatccagtcccactaccagctggaactgcagtgctgc
atcgactggacccatgtcactgaccccctcataggatgcaagaagccagtgtctgcctca
gggaaggagatggattgggcacagatggcatgtcaccgatgtctggtgtatctgggggat
ttgtcccgatatcagaatgaattagctggcgtagataccgagctgctagccgagagattt
tactaccaagccctgtcagtagctcctcagattggaatgcccttcaatcagctgggcacc
ctggcaggcagcaagtactataatgtggaagccatgtattgctacctgcgctgcatccag
tcagaagtgtcctttgagggagcctatgggaacctcaagcggctgtatgacaaggcagcc
aaaatgtaccaccaactgaagaagtgtgagactcggaaactgtctcctggcaaaaagcga
tgtaaagacattaaaaggttgctagtgaactttatgtatctgcaaagcctcctacagccc
aaaagcagctccgtggactcagagctgacctcactttgccagtcagtcctggaggacttc
aacctctgcctcttctacctgccctcctcacccaacctcagcctggccagtgaggatgag
gaggagtatgagagtggatatgctttcctcccggaccttctcatctttcaaatggtcatc
atctgccttatgtgtgtgcacagcttggagagagcaggatccaagcagtacagtgcagcc
attgccttcaccctggccctcttttcccacctcgtcaatcatgtcaacatacggctgcag
gctgagctggaagagggcgagaatcccgtcccggcattccagagtgatggcacagatgaa
ccagagtccaaggaacctgtggagaaagaggaggagccagatcctgagcctcctcctgta
acaccccaagtgggtgagggcagaaagagccgtaagttctctcgcctctcctgtctccgc
cgtcgccgccacccacccaaagttggtgatgacagtgacctgagtgaaggctttgaatcg
gactcaagccatgactcagcccgggccagtgagggctcagacagtggctctgacaagagt
cttgaaggtgggggaacggcctttgatgctgaaacagactcggaaatgaatagccaggag
tcccgatcagacttggaagatatggaggaagaggaggggacacggtcaccaaccctggag
ccccctcggggcagatcagaggctcccgattccctcaatggcccactgggccccagtgag
gctagcattgccagcaatctacaagccatgtccacccagatgttccagactaagcgctgc
ttccgactggcccccacctttagcaacctgctcctccagcccaccaccaaccctcatacc
tcggccagccacaggccttgcgtcaatggggatgtagacaagccttcagagccagcctct
gaggagggctctgagtcggaggggagtgagtccagtggacgctcctgtcggaatgagcgc
agcatccaggagaagcttcaggtcctgatggccgaaggtctgcttcctgctgtgaaagtc
ttcctggactggcttcggaccaaccccgacctcatcatcgtgtgtgcgcagagctctcaa
agtctgtggaaccgcctgtctgtgttgctgaatctgttgcctgctgctggtgaactccag
gagtctggcctggccttgtgtcctgaggtccaagatcttcttgaaggttgtgaactgcct
gacctcccctctagccttctgctcccagaggacatggctcttcgtaacctgcccccgctc
cgagctgcccacagacgctttaactttgacacggatcggcccctgctcagcaccttagag
gagtcagtggtgcgcatctgctgcatccgcagctttggtcatttcatcgcccgcctgcaa
ggcagcatcctgcagttcaacccagaggttggcatcttcgtcagcattgcccagtctgag
caggagagcctgctgcagcaggcccaggcacagttccgaatggcacaggaggaagctcgt
cggaacaggctcatgagagacatggctcagctacgacttcagctcgaagtgtctcagctg
gagggcagcctgcagcagcccaaggcccagtcagccatgtctccctacctcgtccctgac
acccaggccctctgccaccatctccctgtcatccgccaactggccaccagtggccgcttc
attgtcatcatcccaaggacagtgatcgatggcctggatttgctgaagaaggaacaccca
ggggcccgggatgggattcggtacctggaggcagagtttaaaaaaggaaacaggtacatt
cgctgccagaaagaggtgggaaagagctttgagcggcataagctgaagaggcaggatgca
gatgcctggactctctataagatcctagacagctgcaaacagctgactctggcccagggg
gcaggtgaggaggatccgagtggcatggtgaccatcatcacaggccttccactggacaac
cccagcgtgctttcaggccccatgcaggcagccctgcaggccgctgcccacgccagtgtg
gacatcaagaatgttctggacttctacaagcagtggaaggaaattggttga
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