Homo sapiens (human): 23404
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Entry
23404 CDS
T01001
Symbol
EXOSC2, RRP4, Rrp4p, SHRF, hRrp4p, p7
Name
(RefSeq) exosome component 2
KO
K03679
exosome complex component RRP4
Organism
hsa
Homo sapiens (human)
Pathway
hsa03018
RNA degradation
Disease
H02764
Short stature, hearing loss, retinitis pigmentosa, and distinctive facies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
23404 (EXOSC2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
23404 (EXOSC2)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Core exosome factors
23404 (EXOSC2)
Prokaryotic type
Archeal mRNA degradation factors
Exosome components
Core exosome
23404 (EXOSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RRP4_S1
KH_6
ECR1_N
RRP40_S1
ECR1_N_2
EXOSC1
Motif
Other DBs
NCBI-GeneID:
23404
NCBI-ProteinID:
NP_055100
OMIM:
602238
HGNC:
17097
Ensembl:
ENSG00000130713
UniProt:
Q13868
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:130693760..130704894
Genome browser
AA seq
293 aa
AA seq
DB search
MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV
ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL
RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK
RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC
IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG
NT seq
882 nt
NT seq
+upstream
nt +downstream
nt
atggcgatggagatgaggcttccagtggctcgcaagcctcttagcgagagactgggccgc
gacactaagaaacatctagtggtgccgggggatacaatcactacggacacaggattcatg
cggggccatggaacgtatatgggagaagagaagctcattgcatctgttgctggctctgtg
gagagagtaaacaagttgatctgtgtgaaagctttgaaaaccagatacattggtgaagta
ggagacatcgtagtgggacgaatcacagaggttcaacagaagaggtggaaggtggagacc
aactccaggctggattcggtcttgctgctctcgtccatgaaccttcctggaggagagctg
aggagaagatctgcagaagatgagcttgcaatgagaggtttcttacaggaaggggacctt
atcagtgctgaggtccaggcagtgttctctgacggagctgtctctttgcacacgaggagc
ctgaaatatggaaaactaggtcagggggttttggtccaggtttccccctccctggtgaaa
cggcagaagacccactttcatgatttgccatgtggtgcctcagtgattctcggtaacaac
ggcttcatctggatttacccaacacctgagcacaaagaagaggaagcagggggcttcatt
gcaaacctggagcctgtctctcttgctgatcgagaggtgatatcccggcttcggaactgc
atcatctcgctggtaactcagaggatgatgctgtatgataccagcatcctgtactgctat
gaagcatcccttccacatcagatcaaagacatcttaaagccagaaataatggaggagatt
gtgatggaaacacgccagaggcttttggaacaggagggataa
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integrated database retrieval system