Homo sapiens (human): 23417
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Entry
23417 CDS
T01001
Symbol
MLYCD, MCD
Name
(RefSeq) malonyl-CoA decarboxylase
KO
K01578
malonyl-CoA decarboxylase [EC:
4.1.1.9
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00410
beta-Alanine metabolism
hsa00640
Propanoate metabolism
hsa01100
Metabolic pathways
hsa04146
Peroxisome
hsa04152
AMPK signaling pathway
hsa04936
Alcoholic liver disease
Disease
H01283
Malonyl-CoA decarboxylase deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
23417 (MLYCD)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
23417 (MLYCD)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
23417 (MLYCD)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
23417 (MLYCD)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
23417 (MLYCD)
Enzymes [BR:
hsa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.9 malonyl-CoA decarboxylase
23417 (MLYCD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
MCD
MCD_N
Motif
Other DBs
NCBI-GeneID:
23417
NCBI-ProteinID:
NP_036345
OMIM:
606761
HGNC:
7150
Ensembl:
ENSG00000103150
Pharos:
O95822
(Tchem)
UniProt:
O95822
Structure
PDB
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All DBs
Position
16:83899115..83927031
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AA seq
493 aa
AA seq
DB search
MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKT
PAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAA
VLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNG
VLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFF
SHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQG
VELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSEC
KEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVA
NFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQV
LSLVAQFQKNSKL
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcgaggcttcgggccaggcttgacggccaggcgtctcctcccgctgcggttgcccccg
cggccgcccgggccccggctggcgagcgggcaggcggccggcgccctggagcgggccatg
gacgagctgctgcgccgcgcggtgccgccgacgccggcctacgagctgcgcgagaagaca
ccggcgcccgccgagggtcagtgcgcggacttcgtgagcttctacggtgggctggccgag
acggcccagcgggccgaactgctgggccgcctggcgcggggcttcggcgtggaccacggc
caggtggcggagcagagcgccggcgtgctccatctgcgccagcagcagcgggaggcggcg
gtgctgctgcaggccgaggaccggctgcgctacgcgctggtgccgcgctatcgcggcctc
ttccaccacatcagcaagctggacggcggcgtgcgcttcctggtgcagctgcgggccgac
ctgctggaggcgcaggccctcaagctggtggaggggccggacgtccgggaaatgaatggg
gtgctgaaaggaatgctctcagaatggttttcctccgggttcctgaacctagaacgggtt
acctggcattcaccgtgtgaagtgcttcagaaaatcagtgaggctgaggctgtgcatcct
gtaaaaaactggatggacatgaagcgccgcgttgggccctacagaaggtgttacttcttt
tctcactgttcgacccctggggagcccctggtcgttttgcacgtggcactgactggtgac
atctccagcaacatccaggcaatcgtgaaggaacatcctccatcagaaacagaagagaag
aacaaaatcactgctgcgatcttttattccatcagcttgacccagcagggactccaaggg
gtggagctgggaacattcctcataaagcgagtcgtcaaggagttgcagagagagtttcct
caccttggggtgttttcaagtctgtcacctatacctggtttcaccaaatggcttctgggg
cttctgaactcgcaaacgaaggagcatgggaggaatgaactctttacagattcggaatgt
aaggaaatctcggagatcacaggtggccccattaacgagaccctcaagctcctcctcagc
agcagcgagtgggtgcagtcggagaagctggtgcgggcgctgcagactccgctgatgagg
ctgtgcgcctggtacctgtatggagagaagcaccgcggctacgcgctgaaccccgtggcc
aacttccacctgcagaacggggcggtgctgtggcgcatcaactggatggcggatgtgagc
ctcagaggcatcaccggctcctgcggcctgatggccaactaccgctacttcctggaggag
acgggccccaacagcacctcctacctcggctccaagatcatcaaagcctctgagcaggtc
ctcagcctagtggcccagtttcaaaagaacagcaagctctga
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