Homo sapiens (human): 23503
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Entry
23503 CDS
T01001
Symbol
ZFYVE26, FYVE-CENT, SPG15
Name
(RefSeq) zinc finger FYVE domain-containing protein 26
KO
K19027
zinc finger FYVE domain-containing protein 26
Organism
hsa
Homo sapiens (human)
Pathway
hsa04142
Lysosome biogenesis
Network
nt06550
Lysosome biogenesis
Element
N02017
Retrieval of the lysosomal sorting receptor (CIMPR) from the endosome
Disease
H00266
Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome biogenesis
23503 (ZFYVE26)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
23503 (ZFYVE26)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Other HR factors
23503 (ZFYVE26)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TPR_ZFYVE26
FYVE
TPR_2
Motif
Other DBs
NCBI-GeneID:
23503
NCBI-ProteinID:
NP_056161
OMIM:
612012
HGNC:
20761
Ensembl:
ENSP00000251119.5
UniProt:
Q68DK2
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:complement(67728892..67816590)
Genome browser
AA seq
2539 aa
AA seq
DB search
MNHPFGKEEAASQKQLFGFFCECLRRGEWELAQACVPQLQEGQGDIPKRVEDILQALVVC
PNLLRCGQDINPQRVAWVWLLVLEKWLAREKKLLPVVFRRKLEFLLLSEDLQGDIPENIL
EELYETLTQGAVGHVPDGNPRRESWTPRLSSEAVSVLWDLLRQSPQPAQALLELLLEEDD
GTGLCHWPLQNALVDLIRKALRALQGPDSVPPGVVDAIYGALRTLRCPAEPLGVELHLLC
EELLEACRTEGSPLREERLLSCLLHKASRGLLSLYGHTYAEKVTEKPPRATASGKVSPDH
LDPERAMLALFSNPNPAEAWKVAYFYCLSNNKHFLEQILVTALTLLKEEDFPNLGCLLDR
EFRPLSCLLVLLGWTHCQSLESAKRLLQTLHRTQGPGCDELLRDACDGLWAHLEVLEWCI
QQSSNPIPKRDLLYHLHGGDSHSVLYTLHHLTNLPALREEDVLKLLQKVPAKDPQQEPDA
VDAPVPEHLSQCQNLTLYQGFCAMKYAIYALCVNSHQHSQCQDCKDSLSEDLASATEPAN
DSLSSPGAANLFSTYLARCQQYLCSIPDSLCLELLENIFSLLLITSADLHPEPHLPEDYA
EDDDIEGKSPSGLRSPSESPQHIAHPERKSERGSLGVPKTLAYTMPSHVKAEPKDSYPGP
HRHSFLDLKHFTSGISGFLADEFAIGAFLRLLQEQLDEISSRSPPEKPKQESQSCSGSRD
GLQSRLHRLSKVVSEAQWRHKVVTSNHRSEEQPSRRYQPATRHPSLRRGRRTRRSQADGR
DRGSNPSLESTSSELSTSTSEGSLSAMSGRNELHSRLHPHPQSSLIPMMFSPPESLLASC
ILRGNFAEAHQVLFTFNLKSSPSSGELMFMERYQEVIQELAQVEHKIENQNSDAGSSTIR
RTGSGRSTLQAIGSAAAAGMVFYSISDVTDKLLNTSGDPIPMLQEDFWISTALVEPTAPL
REVLEDLSPPAMAAFDLACSQCQLWKTCKQLLETAERRLNSSLERRGRRIDHVLLNADGI
RGFPVVLQQISKSLNYLLMSASQTKSESVEEKGGGPPRCSITELLQMCWPSLSEDCVASH
TTLSQQLDQVLQSLREALELPEPRTPPLSSLVEQAAQKAPEAEAHPVQIQTQLLQKNLGK
QTPSGSRQMDYLGTFFSYCSTLAAVLLQSLSSEPDHVEVKVGNPFVLLQQSSSQLVSHLL
FERQVPPERLAALLAQENLSLSVPQVIVSCCCEPLALCSSRQSQQTSSLLTRLGTLAQLH
ASHCLDDLPLSTPSSPRTTENPTLERKPYSSPRDSSLPALTSSALAFLKSRSKLLATVAC
LGASPRLKVSKPSLSWKELRGRREVPLAAEQVARECERLLEQFPLFEAFLLAAWEPLRGS
LQQGQSLAVNLCGWASLSTVLLGLHSPIALDVLSEAFEESLVARDWSRALQLTEVYGRDV
DDLSSIKDAVLSCAVACDKEGWQYLFPVKDASLRSRLALQFVDRWPLESCLEILAYCISD
TAVQEGLKCELQRKLAELQVYQKILGLQSPPVWCDWQTLRSCCVEDPSTVMNMILEAQEY
ELCEEWGCLYPIPREHLISLHQKHLLHLLERRDHDKALQLLRRIPDPTMCLEVTEQSLDQ
HTSLATSHFLANYLTTHFYGQLTAVRHREIQALYVGSKILLTLPEQHRASYSHLSSNPLF
MLEQLLMNMKVDWATVAVQTLQQLLVGQEIGFTMDEVDSLLSRYAEKALDFPYPQREKRS
DSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPSQEFVPP
ATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENP
ARVCDQCYSYCNKDVPEEPSEKPEALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENE
LVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSKGLTNPEVDAGLLTDIMK
QLLFSAKMMFVKAGQSQDLALCDSYISKVDVLNILVAAAYRHVPSLDQILQPAAVTRLRN
QLLEAEYYQLGVEVSTKTGLDTTGAWHAWGMACLKAGNLTAAREKFSRCLKPPFDLNQLN
HGSRLVQDVVEYLESTVRPFVSLQDDDYFATLRELEATLRTQSLSLAVIPEGKIMNNTYY
QECLFYLHNYSTNLAIISFYVRHSCLREALLHLLNKESPPEVFIEGIFQPSYKSGKLHTL
ENLLESIDPTLESWGKYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAK
SYTELGEKLSWLLKAKDHLKIYLQETSRSSGRKKTTFFRKKMTAADVSRHMNTLQLQMEV
TRFLHRCESAGTSQITTLPLPTLFGNNHMKMDVACKVMLGGKNVEDGFGIAFRVLQDFQL
DAAMTYCRAARQLVEKEKYSEIQQLLKCVSESGMAAKSDGDTILLNCLEAFKRIPPQELE
GLIQAIHNDDNKVRAYLICCKLRSAYLIAVKQEHSRATALVQQVQQAAKSSGDAVVQDIC
AQWLLTSHPRGAHGPGSRK
NT seq
7620 nt
NT seq
+upstream
nt +downstream
nt
atgaatcatccatttggaaaagaggaagctgcttcgcagaagcagctttttggatttttc
tgcgaatgcctgcggaggggagaatgggagctggcacaggcatgtgtacctcagctacag
gagggacaaggggatatcccaaagagggtagaagacatacttcaggcattggtggtgtgt
ccaaatctgctgagatgtgggcaggacatcaaccctcaaagagtagcctgggtctggctt
cttgtactggagaaatggttggcccgggaaaagaagttactcccagttgttttccggaga
aagcttgagtttcttttattgtcagaagacctccaaggtgacattccagagaacatcctc
gaggagctgtatgagaccttaacacagggtgcagtaggccacgtgcctgacggaaatcca
aggagggagagctggactcctcgtctcagctccgaagctgtctctgtgctctgggatctc
ctgaggcagtctccccagccagcacaggccctgctggagctcctgcttgaggaggatgac
ggtactggcctctgtcactggcctctgcagaatgcactggtggacctcattcgaaaggca
ttgcgggctttgcagggccctgattcggtgccccctggggtagtcgatgccatctatgga
gccctgcggactctgcgttgccccgcagaaccacttggggttgagttgcatctcctgtgt
gaggaactactagaggcctgcaggaccgaggggagtcccctgcgggaggagcggctgctc
agctgcctgctgcacaaggccagccggggcctgctgtccctgtatggccatacctatgca
gagaaggtcacagaaaagccaccgagggctacagcctcgggaaaagtctcaccggatcat
ctagatcctgagcgggcaatgctagccctgttctccaatcccaacccagccgaggcttgg
aaagtggcctatttctactgcctgagcaacaacaaacacttcctcgagcagattctggta
acagcactaacattgttgaaagaagaagacttcccaaatcttggctgcctacttgataga
gaattcaggcccctcagttgcctgcttgtactcctgggctggacacactgccagagccta
gagtcagccaagaggctgctccagaccctgcacaggacccagggcccaggctgtgatgag
ctcctcagggatgcctgtgatgggttgtgggctcacctggaggtcctggagtggtgcata
cagcagagcagcaaccccataccaaagagagatctgttgtatcatttacacggtggagac
agccactcagtgctctacactctccatcaccttacaaaccttccagccctcagggaggaa
gatgttctcaagctcttacagaaagtgccagccaaggacccccagcaagagcctgatgca
gttgatgctccagtccctgagcacctgagccagtgtcagaacctgacactctaccagggc
ttctgtgccatgaagtatgccatctatgccctctgtgtaaactcacaccagcactcccag
tgccaggactgcaaagacagcctctctgaggacctggcctcagctacagagccagcgaat
gactctctctcctccccaggtgctgcaaatctcttctcaacttacctggccaggtgtcaa
cagtatctgtgcagtattcctgactctctgtgcctggagcttctggaaaacatcttctca
ttgcttctcatcacctctgctgatcttcacccagagcctcacttgcctgaggactatgct
gaggatgatgacattgaggggaagagcccctcaggtttgaggtccccatcagagagccct
cagcacatagcacatcctgaaaggaagtcagaacggggttccctgggagtcccaaagacc
cttgcttatacaatgccaagccatgtgaaggcagagccaaaagacagttacccagggcct
cataggcacagctttttggacttaaaacactttactagtggtatcagtggatttctggct
gatgaatttgcaataggggccttcctcaggcttctccaagagcaactggatgagatcagt
agccgcagccctcctgagaagccaaagcaagaaagtcagagctgctcaggaagcagagat
ggactgcagagccgcctgcatcgactttccaaggttgtctctgaggcccagtggagacac
aaggtggtgacaagcaaccatcgttcagaggagcaaccttcccgaagataccagcctgcc
acacgtcaccccagtctccgccggggtcgtcggacaagaaggagccaggcagatggccga
gacagaggttcaaacccatccctggaaagtacaagtagtgagctgagcacaagtacgtca
gagggaagtctgagtgccatgtctggccggaatgagctgcacagtagattgcacccccat
cctcaaagttcactcatccccatgatgttctccccacctgagtcactgctggcatcctgc
atccttcgcgggaacttcgcagaagcccatcaggtgctgttcacgttcaacctgaagtcc
tcacccagttcaggggaactgatgttcatggagcgctaccaggaagtgatccaagaactg
gcccaagtagagcacaagattgaaaaccagaactcagatgcgggtagcagcaccattcgg
agaactggcagtggccgctcaactctacaggccattggcagcgctgcagcagcaggaatg
gtgttttactctatctctgacgtgactgacaagctgctcaacacctctggagaccccatc
cccatgctccaggaggacttttggataagcacggctctagtggagcccactgctcccctg
agagaggttctggaagacctcagtccccctgccatggctgcatttgacctagcttgctct
cagtgccagctctggaaaacctgcaagcagcttttggagacagccgaacggcgtttgaat
agtagccttgaaaggcggggtcgacggatagaccacgtactcctaaatgctgatggcatt
cgaggttttccagttgttcttcagcaaatcagtaagagtctcaattatctgcttatgtca
gccagtcaaaccaaatcagagagtgtggaagaaaagggaggaggccctccacggtgcagc
atcactgaactgcttcagatgtgctggcccagcctaagcgaggactgtgttgccagccac
accaccctctcccagcagctagatcaggtccttcagtcactgagagaggcactagagctg
ccagagcccaggactcctccactgtcttccctggtggagcaggcagcccagaaagctcca
gaggcagaggcccaccctgtgcagatccagactcagctcctccagaagaacctgggcaaa
cagaccccatcaggcagcaggcagatggactacttgggcaccttcttcagttactgcagc
acccttgctgcagttctccttcaaagtttgagctctgagcctgatcatgtggaggtcaag
gtaggaaatccctttgttctgctgcaacagagctcttcccaactggtgtcacatctcctg
tttgagagacaagttcccccagagagactggcagcccttctggcccaagagaatctcagc
ctaagtgtgccacaggtcatcgtcagctgctgctgtgagccccttgctctttgctcatcc
cggcaaagccagcagacctcctccctcctgactcgtctgggtactctggcccagctacac
gcctctcactgcctggatgacctcccactttctacaccgagctccccgaggacaactgag
aaccctacattggaaagaaagccctactcctccccaagggactcatcactcccagccctc
acctcctctgccttggcctttcttaagtcacgctcaaagctcctagctacggtggcctgc
ctgggggcttccccgaggttaaaggtcagcaaacccagcttgtcatggaaggaacttcgt
ggccgcagggaggtgcctctggctgcagagcaggtagcccgggagtgtgagcgccttctg
gaacaattccctctgtttgaggccttcctcctggctgcctgggagcccctgcgagggtct
ttgcagcaggggcagagtctggcagtgaatctctgtggttgggccagtctttctaccgtt
ctcctgggcctacattctcccattgccctagatgtactgagtgaggcttttgaggaatcc
ttggtggccagagattggtcccgggcccttcagctcactgaagtgtacgggcgagatgtg
gacgatttgagcagcataaaggatgcagtcctgagctgtgctgtggcatgtgacaaagaa
ggttggcaatacctgtttcccgtgaaggatgcatctctgagaagtcggctggccctacag
tttgtggacaggtggcccctggagtcatgcctggagattctggcctactgcatttcagac
acggctgtccaagaaggactaaagtgtgagctacagaggaagctggcggagctgcaggtg
tatcagaagattctgggtttgcagtctcccccagtgtggtgtgactggcagaccttgagg
agctgttgtgttgaggacccatcaactgtcatgaacatgattctagaagcacaggagtat
gaactgtgtgaagagtggggctgcctgtaccccattccaagagaacatttaatcagcctt
catcaaaagcatcttctccaccttctagaaagaagagatcatgacaaggctctgcaactc
ctgcgaagaatccctgaccccaccatgtgccttgaagtgacagagcaatccctcgaccag
cacactagcttggccacttctcacttcttggccaactacctcaccacccacttctatgga
caactgactgctgtccgacaccgtgaaatccaggcgctgtatgtgggatccaagattctg
ctgaccctgcctgagcagcaccgggccagctattcccacttgtcctctaaccccctgttc
atgctggagcagctgcttatgaacatgaaggtggattgggccactgtggctgtgcagact
ctccagcagctgctggttggacaggagattggcttcactatggacgaggtggactcactg
ctttccagatacgcagagaaagccctggactttccataccctcagagggagaaacgatca
gattctgtgattcacctccaagaaattgtccaccaggctgcagatcccgagaccctccct
agatcaccatcagcagagttctctcctgctgctcctcctggtatctccagtatacattcc
cctagtctaagggaaaggagtttcccaccaacccagccctcacaggaatttgtgccccca
gcgacaccccctgccaggcaccagtgggtaccggatgagactgagagtatctgcatggtc
tgctgcagggagcacttcaccatgtttaacaggcgtcatcattgtcgccgctgtggccgg
ctagtgtgcagctcctgctccactaagaaaatggtggttgaaggctgcagagagaaccct
gctcgtgtgtgtgatcagtgctatagttactgcaacaaagatgtaccagaggagccttca
gaaaaaccagaagctctagacagctccaagaatgaaagccctccatactcgtttgtggtg
agagtccccaaagcagatgaggtggaatggattttggatctcaaagaggaggaaaatgag
ctggtgcggagtgaattttactatgagcaggcccccagcgcctccttgtgcattgccatc
ctgaatctgcaccgggacagcattgcctgtggtcaccagctgattgagcactgctgcagg
ctctccaagggcctcaccaacccagaggtggatgccgggctgctcacggacatcatgaag
cagctgctgttcagcgccaagatgatgttcgtcaaagccggccagagccaagacttggct
ctttgtgacagctacatcagcaaggtagatgtgctgaatattttagttgctgctgcctat
cgccacgtgccatctttggatcagatcttgcagccagctgcagtaaccaggctaaggaac
cagcttttggaagccgagtactaccaactgggcgttgaggtctccacaaagactgggctt
gataccaccggggcgtggcatgcttggggcatggcctgcctcaaagccgggaacctcact
gctgcacgggagaagttcagtcgctgtctgaagcccccatttgacctcaatcagctgaat
catggctcaaggctggtgcaggatgtggttgagtacctagagtccacagtgaggcccttt
gtatccttgcaagatgacgattactttgccaccctgagggaactggaagctacccttcgg
acgcagagcctttctctggcagtgattcctgaagggaaaatcatgaacaacacctactac
caggaatgcctcttctacctgcacaactatagcaccaacctggccatcatcagcttctac
gtgaggcacagctgcctgcgggaagctcttctgcaccttctcaacaaggagagtcctcca
gaagtttttatagaaggcattttccaaccaagctataaaagtgggaagctacacactttg
gagaacttgctagaatccattgatccaaccttggagagctggggaaagtacttgattgct
gcctgccaacatttacagaagaagaactactaccacattctgtatgagctgcagcagttt
atgaaggaccaagttcgggccgccatgacctgtattcggttcttcagtcacaaagcaaag
tcatatacagaactgggagagaagctctcatggctacttaaggccaaggaccacctgaag
atctacctccaagaaacatcccgcagctctggaaggaagaaaaccacattcttcagaaag
aagatgactgcagctgatgtgtcaaggcacatgaacacacttcagctgcagatggaagtg
accaggttcttgcatcggtgcgaaagtgctgggacctctcaaatcaccactttgcctctg
ccaaccctgtttggaaataaccacatgaaaatggatgttgcctgcaaggtcatgctggga
gggaaaaatgtagaagatggttttggaattgctttccgtgttctgcaggacttccagctg
gatgctgccatgacctactgcagagctgcccgccagttggtggagaaagagaagtacagt
gagatccagcaactgctcaaatgtgtcagtgagtcaggcatggcagccaaaagtgacggg
gacaccatcctcctcaactgcctggaagcgttcaagagaattccgccccaggagctggag
ggcctgatccaggcaatacacaatgatgacaacaaggttcgggcctacctgatatgttgc
aaactgcgttctgcctacttgattgctgtgaagcaagaacactcacgggccacagccctt
gtccagcaggtgcagcaggccgccaagagcagcggggatgcagtagtgcaagacatctgt
gcccagtggcttctgacaagccacccccggggtgcccatggcccaggctccaggaagtga
DBGET
integrated database retrieval system
