Homo sapiens (human): 23507
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Entry
23507 CDS
T01001
Symbol
LRRC8B, TA-LRRP, TALRRP
Name
(RefSeq) leucine rich repeat containing 8 VRAC subunit B
KO
K22038
volume-regulated anion channel
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
23507 (LRRC8B)
Ion channels [BR:
hsa04040
]
Chloride channels
Chloride channel, volume-regulated (VRAC)
23507 (LRRC8B)
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Gene cluster
GFIT
Motif
Pfam:
Pannexin_like
LRR_8
LRR_14
LRR_4
LRR_5
LRR_1
LRR_9
LRR_LRWD1
Motif
Other DBs
NCBI-GeneID:
23507
NCBI-ProteinID:
NP_001127948
OMIM:
612888
HGNC:
30692
Ensembl:
ENSG00000197147
UniProt:
Q6P9F7
A0A384N5V6
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All DBs
Position
1:89524829..89597861
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AA seq
803 aa
AA seq
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MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
EENLLNTLPLPVTERLQTCLDKC
NT seq
2412 nt
NT seq
+upstream
nt +downstream
nt
atgattacactaactgagctaaaatgcttagcagatgcccagtcatcttatcacatctta
aaaccatggtgggacgtcttctggtattacatcacactgatcatgctgctggtggccgtg
ctggccggagctctccagctgacgcagagcagggttctgtgctgtcttccatgcaaagtg
gaatttgacaatcactgtgccgtgccttgggacatcctgaaagccagcatgaacacatcc
tctaatcctgggacaccgcttccgctccccctccgaattcagaatgacctccaccgacag
cagtactcctatattgatgccgtctgttacgagaaacagctccattggtttgcaaagttt
ttcccctatctggtgctcttgcacacgctcatctttgcagcctgcagcaacttttggctt
cactaccccagtaccagttccaggctcgagcattttgtggccatccttcacaagtgcttc
gattctccatggaccacccgcgccctttcagaaacagtggctgagcagtcagtgaggcct
ctgaaactctccaagtccaagattttgctttcgtcctcagggtgttcagctgacatagat
tccggcaaacagtcattgccctacccacagccaggtttggagtcagctggcatagaaagc
ccaacttccagtgtcctggacaagaaggagggtgaacaggccaaagccatctttgaaaaa
gtgaaaagattccgcatgcatgtggagcagaaggacatcatttatagagtatatctgaaa
cagataatagtcaaagtcattttgtttgtgctcatcataacttatgttccatatttttta
acccacatcactcttgaaatcgactgttcagttgatgtgcaggcttttacaggatataag
cgctaccagtgtgtctattccttggcagaaatctttaaggtcctggcttcattttatgtc
attttggttatactttatggtctgacctcttcctacagcctgtggtggatgctgaggagt
tccctgaagcaatattcctttgaggcgttaagagaaaaaagcaactacagtgacatccct
gatgtcaagaatgactttgccttcatccttcatctggctgatcagtatgatcctctttat
tccaaacgcttctccatattcctatcagaggtcagtgagaacaaactgaaacagatcaac
ctcaataatgaatggacagttgagaaactgaaaagtaagcttgtgaaaaatgcccaggac
aagatagaactgcatctttttatgctcaacggtcttccagacaatgtctttgagttaact
gaaatggaagtgctaagcctggagcttatcccagaggtgaagctgccctctgcagtctca
cagctggtcaacctcaaggagcttcgtgtgtaccattcatctctggtcgtagaccatcct
gcactggcctttctagaggagaatttaaaaatcctccgcctgaaatttactgaaatggga
aaaatcccacgctgggtatttcacctcaagaatctcaaggaactttatctttcgggctgt
gttctccctgaacagttgagtactatgcagttggagggctttcaggacttaaaaaatcta
aggaccctgtacttgaagagcagcctctcccggatcccacaagttgttacagacctcctg
ccttcattgcagaaactgtcccttgataatgagggaagcaaactggttgtgttgaacaac
ttgaaaaagatggtcaatctgaaaagcctagaactgatcagctgtgacctggaacgcatc
ccacattccattttcagcctgaataatttgcatgagttagacctaagggaaaataacctt
aaaactgtggaagagatcattagctttcagcatcttcagaatctttcctgcttaaagttg
tggcacaataacattgcttatattcctgcacagattggggcattatctaacctagagcag
ctctctttggaccataataatattgagaatctgcccttgcagcttttcctatgcactaaa
ctacattatttggatctaagctataaccacttgaccttcattccagaagaaatccagtat
ctgagtaatttgcagtactttgctgtgaccaacaacaatattgagatgctaccagatggg
ctgtttcagtgcaaaaagctgcagtgtttacttttggggaaaaatagcttgatgaatttg
tcccctcatgtgggtgagctgtcaaaccttactcatctggagctcattggtaattacctg
gaaacacttcctcctgaactagaaggatgtcagtccctaaaacggaactgtctgattgtt
gaggagaacttgctcaatactcttcctctccctgtaacagaacgtttacagacgtgctta
gacaaatgttga
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