Homo sapiens (human): 23569
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Entry
23569 CDS
T01001
Symbol
PADI4, PAD, PAD4, PADI5, PDI4, PDI5
Name
(RefSeq) protein-arginine deiminase type-4
KO
K24669
protein-arginine deiminase 4 [EC:
3.5.3.15
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04613
Neutrophil extracellular trap formation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
23569 (PADI4)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.3 In linear amidines
3.5.3.15 protein-arginine deiminase
23569 (PADI4)
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Motif
Pfam:
PAD
PAD_M
PAD_N
Motif
Other DBs
NCBI-GeneID:
23569
NCBI-ProteinID:
NP_036519
OMIM:
605347
HGNC:
18368
Ensembl:
ENSP00000364597.4
UniProt:
Q9UM07
Structure
PDB
PDBj
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All DBs
Position
1:17308197..17364004
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AA seq
663 aa
AA seq
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MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK
KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD
ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM
SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP
NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP
HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG
KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS
FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK
PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN
MVP
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atggcccaggggacattgatccgtgtgaccccagagcagcccacccatgccgtgtgtgtg
ctgggcaccttgactcagcttgacatctgcagctctgcccctgaggactgcacgtccttc
agcatcaacgcctccccaggggtggtcgtggatattgcccacggccctccagccaagaag
aaatccacaggttcctccacatggcccctggaccctggggtagaggtgaccctgacgatg
aaagtggccagtggtagcacaggcgaccagaaggttcagatttcatactacggacccaag
actccaccagtcaaagctctactctacctcaccggggtggaaatctccttgtgcgcagac
atcacccgcaccggcaaagtgaagccaaccagagctgtgaaagatcagaggacctggacc
tggggcccttgtggacagggtgccatcctgctggtgaactgtgacagagacaatctcgaa
tcttctgccatggactgcgaggatgatgaagtgcttgacagcgaagacctgcaggacatg
tcgctgatgaccctgagcacgaagacccccaaggacttcttcacaaaccatacactggtg
ctccacgtggccaggtctgagatggacaaagtgagggtgtttcaggccacacggggcaaa
ctgtcctccaagtgcagcgtagtcttgggtcccaagtggccctctcactacctgatggtc
cccggtggaaagcacaacatggacttctacgtggaggccctcgctttcccggacaccgac
ttcccggggctcattaccctcaccatctccctgctggacacgtccaacctggagctcccc
gaggctgtggtgttccaagacagcgtggtcttccgcgtggcgccctggatcatgaccccc
aacacccagcccccgcaggaggtgtacgcgtgcagtatttttgaaaatgaggacttcctg
aagtcagtgactactctggccatgaaagccaagtgcaagctgaccatctgccctgaggag
gagaacatggatgaccagtggatgcaggatgaaatggagatcggctacatccaagcccca
cacaaaacgctgcccgtggtcttcgactctccaaggaacagaggcctgaaggagtttccc
atcaaacgcgtgatgggtccagattttggctatgtaactcgagggccccaaacagggggt
atcagtggactggactcctttgggaacctggaagtgagccccccagtcacagtcaggggc
aaggaatacccgctgggcaggattctcttcggggacagctgttatcccagcaatgacagc
cggcagatgcaccaggccctgcaggacttcctcagtgcccagcaggtgcaggcccctgtg
aagctctattctgactggctgtccgtgggccacgtggacgagttcctgagctttgtgcca
gcacccgacaggaagggcttccggctgctcctggccagccccaggtcctgctacaaactg
ttccaggagcagcagaatgagggccacggggaggccctgctgttcgaagggatcaagaaa
aaaaaacagcagaaaataaagaacattctgtcaaacaagacattgagagaacataattca
tttgtggagagatgcatcgactggaaccgcgagctgctgaagcgggagctgggcctggcc
gagagtgacatcattgacatcccgcagctcttcaagctcaaagagttctctaaggcggaa
gcttttttccccaacatggtgaacatgctggtgctagggaagcacctgggcatccccaag
cccttcgggcccgtcatcaacggccgctgctgcctggaggagaaggtgtgttccctgctg
gagccactgggcctccagtgcaccttcatcaacgacttcttcacctaccacatcaggcat
ggggaggtgcactgcggcaccaacgtgcgcagaaagcccttctccttcaagtggtggaac
atggtgccctga
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