Homo sapiens (human): 247
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Entry
247 CDS
T01001
Symbol
ALOX15B, 15-LOX-2
Name
(RefSeq) arachidonate 15-lipoxygenase type B
KO
K08022
arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:
1.13.11.33
1.13.11.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00590
Arachidonic acid metabolism
hsa01100
Metabolic pathways
hsa04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
247 (ALOX15B)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
247 (ALOX15B)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.33 arachidonate 15-lipoxygenase
247 (ALOX15B)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
DNA_pol3_tau_4
Motif
Other DBs
NCBI-GeneID:
247
NCBI-ProteinID:
NP_001132
OMIM:
603697
HGNC:
434
Ensembl:
ENSG00000179593
UniProt:
O15296
Structure
PDB
PDBj
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All DBs
Position
17:8039059..8049134
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AA seq
676 aa
AA seq
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MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED
VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE
GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK
NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS
QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT
NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV
RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL
IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI
WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ
YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT
CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL
PYTYLDPPLIENSVSI
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atggccgagttcagggtcagggtgtccaccggagaagccttcggggctggcacatgggac
aaagtgtctgtcagcatcgtggggacccggggagagagccccccactgcccctggacaat
ctcggcaaggagttcactgcgggcgctgaggaggacttccaggtgacgctcccggaggac
gtaggccgagtgctgctgctgcgcgtgcacaaggcgcccccagtgctgcccctgctgggg
cccctggccccggatgcctggttctgccgctggttccagctgacaccgccgcggggcggc
cacctcctcttcccctgctaccagtggctggagggggcggggaccctggtgctgcaggag
ggtacagccaaggtgtcctgggcagaccaccaccctgtgctccagcaacagcgccaggag
gagcttcaggcccggcaggagatgtaccagtggaaggcttacaacccaggttggcctcac
tgcctggatgaaaagacagtggaagacttggagctcaatatcaaatactccacagccaag
aatgccaacttttatctacaggctggctctgcttttgcagagatgaaaatcaaggggttg
ctggaccgcaaggggctctggaggagtctgaatgagatgaaaaggatcttcaacttccgg
aggaccccagcagctgagcacgcatttgagcactggcaggaggacgccttcttcgcctcc
cagttcctgaatggtctcaaccctgtcctgatccgccgctgtcactacctcccaaagaac
ttccccgtcactgatgccatggtggcctcagtgttgggtcctgggaccagcttgcaggct
gagctagagaagggctccctgttcttggtggatcacggcatcctctctggcatccagacc
aatgtcattaatgggaagcctcagttctctgcggccccaatgaccctgctataccagagc
ccaggctgcgggccgctgctgcctctcgccatccagctcagccagacccccggcccaaac
agccccatcttcctgcccactgatgacaagtgggactggttgctggccaagacctgggtg
cgcaatgccgagttctccttccatgaggccctcacgcacctgctgcactcacatctgctg
cctgaggtcttcaccctggctaccctgcgtcagctgccccactgccaccctctcttcaag
ctgctgatcccgcacacccgatacaccctgcacatcaacacactcgcccgggagctgctt
atcgtgccagggcaggtggtggacaggtccacaggcatcggcattgaaggcttctctgag
ttgatacagaggaacatgaagcagctgaactattctctcctgtgtctgcctgaggatatc
cggacccgaggagttgaagacatcccaggctactactaccgtgatgatgggatgcagatc
tggggtgcagtggaacgctttgtctctgaaatcatcggtatctactacccaagtgatgag
tctgtccaagatgacagagagctccaggcctgggtcagagagatcttctccaagggcttc
ctaaaccaggagagctcaggtataccctcctcactggagacccgggaagccctggtgcag
tatgtcaccatggtgatattcacctgctccgccaagcatgcggctgtcagtgcagggcag
tttgactcctgtgcttggatgcccaacctgccacccagcatgcagctgccaccacccacc
tccaaaggcctggcaacatgcgagggcttcatagccaccctcccacctgtcaatgccaca
tgtgatgtcatccttgctctctggttgctgagcaaggagcctggagaccaaaggcccctg
ggcacctatccggatgagcacttcacagaggaggcccctcggcggagcatcgccaccttc
cagagccgcctggcccagatctcgaggggcatccaggagcggaaccagggcctggtgctg
ccctacacctacctagaccctcccctcatcgagaacagcgtctccatctaa
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