KEGG   Homo sapiens (human): 2538
Entry
2538              CDS       T01001                                 
Symbol
G6PC1, G6PC, G6PT, G6Pase, GSD1, GSD1a
Name
(RefSeq) glucose-6-phosphatase catalytic subunit 1
  KO
K01084  glucose-6-phosphatase [EC:3.1.3.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00052  Galactose metabolism
hsa00500  Starch and sucrose metabolism
hsa01100  Metabolic pathways
hsa04068  FoxO signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
hsa04922  Glucagon signaling pathway
hsa04931  Insulin resistance
hsa04973  Carbohydrate digestion and absorption
Network
nt06017  Glycogen metabolism
  Element
N00718  Glycogen degradation
Disease
H00069  Glycogen storage disease
H01760  Hepatic glycogen storage disease
H01939  Glycogen storage disease type I
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    2538 (G6PC1)
   00052 Galactose metabolism
    2538 (G6PC1)
   00500 Starch and sucrose metabolism
    2538 (G6PC1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    2538 (G6PC1)
   04151 PI3K-Akt signaling pathway
    2538 (G6PC1)
   04152 AMPK signaling pathway
    2538 (G6PC1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    2538 (G6PC1)
   04922 Glucagon signaling pathway
    2538 (G6PC1)
   04920 Adipocytokine signaling pathway
    2538 (G6PC1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    2538 (G6PC1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    2538 (G6PC1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.9  glucose-6-phosphatase
     2538 (G6PC1)
SSDB
Motif
Pfam: PAP2 DUF373
Other DBs
NCBI-GeneID: 2538
NCBI-ProteinID: NP_000142
OMIM: 613742
HGNC: 4056
Ensembl: ENSG00000131482
UniProt: P35575
LinkDB
Position
17:42900799..42914438
AA seq 357 aa
MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIK
LLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCETGPGSPSGHA
MGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQ
VVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKGLGVDLLWTLEK
AQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIV
ASLVLLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVIPYCLAQVLGQPHKKSL
NT seq 1074 nt   +upstreamnt  +downstreamnt
atggaggaaggaatgaatgttctccatgactttgggatccagtcaacacattacctccag
gtgaattaccaagactcccaggactggttcatcttggtgtccgtgatcgcagacctcagg
aatgccttctacgtcctcttccccatctggttccatcttcaggaagctgtgggcattaaa
ctcctttgggtagctgtgattggagactggctcaacctcgtctttaagtggattctcttt
ggacagcgtccatactggtgggttttggatactgactactacagcaacacttccgtgccc
ctgataaagcagttccctgtaacctgtgagactggaccagggagcccctctggccatgcc
atgggcacagcaggtgtatactacgtgatggtcacatctactctttccatctttcaggga
aagataaagccgacctacagatttcggtgcttgaatgtcattttgtggttgggattctgg
gctgtgcagctgaatgtctgtctgtcacgaatctaccttgctgctcattttcctcatcaa
gttgttgctggagtcctgtcaggcattgctgttgcagaaactttcagccacatccacagc
atctataatgccagcctcaagaaatattttctcattaccttcttcctgttcagcttcgcc
atcggattttatctgctgctcaagggactgggtgtagacctcctgtggactctggagaaa
gcccagaggtggtgcgagcagccagaatgggtccacattgacaccacaccctttgccagc
ctcctcaagaacctgggcacgctctttggcctggggctggctctcaactccagcatgtac
agggagagctgcaaggggaaactcagcaagtggctcccattccgcctcagctctattgta
gcctccctcgtcctcctgcacgtctttgactccttgaaacccccatcccaagtcgagctg
gtcttctacgtcttgtccttctgcaagagtgcggtagtgcccctggcatccgtcagtgtc
atcccctactgcctcgcccaggtcctgggccagccgcacaagaagtcgttgtaa

KEGG   Homo sapiens (human): 57818
Entry
57818             CDS       T01001                                 
Symbol
G6PC2, IGRP
Name
(RefSeq) glucose-6-phosphatase catalytic subunit 2
  KO
K01084  glucose-6-phosphatase [EC:3.1.3.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00052  Galactose metabolism
hsa00500  Starch and sucrose metabolism
hsa01100  Metabolic pathways
hsa04068  FoxO signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
hsa04922  Glucagon signaling pathway
hsa04931  Insulin resistance
hsa04973  Carbohydrate digestion and absorption
Network
nt06017  Glycogen metabolism
  Element
N00718  Glycogen degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    57818 (G6PC2)
   00052 Galactose metabolism
    57818 (G6PC2)
   00500 Starch and sucrose metabolism
    57818 (G6PC2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    57818 (G6PC2)
   04151 PI3K-Akt signaling pathway
    57818 (G6PC2)
   04152 AMPK signaling pathway
    57818 (G6PC2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    57818 (G6PC2)
   04922 Glucagon signaling pathway
    57818 (G6PC2)
   04920 Adipocytokine signaling pathway
    57818 (G6PC2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    57818 (G6PC2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    57818 (G6PC2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.9  glucose-6-phosphatase
     57818 (G6PC2)
SSDB
Motif
Pfam: PAP2
Other DBs
NCBI-GeneID: 57818
NCBI-ProteinID: NP_066999
OMIM: 608058
HGNC: 28906
Ensembl: ENSG00000152254
UniProt: Q9NQR9
LinkDB
Position
2:168901291..168910000
AA seq 355 aa
MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV
AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS
CVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVI
LGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWSVPIAK
KWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLLSCRGGNNYTLSFRLLCALTS
LTILQLYHFLQIPTHEEHLFYVLSFCKSASIPLTVVAFIPYSVHMLMKQSGKKSQ
NT seq 1068 nt   +upstreamnt  +downstreamnt
atggatttccttcacaggaatggagtgctcataattcagcatttgcagaaggactaccga
gcttactacacttttctaaattttatgtccaatgttggagaccccaggaatatctttttc
atttattttccactttgttttcaatttaatcagacagttggaaccaagatgatatgggta
gcagtcattggggattggttaaatcttatatttaaatggatattatttggtcatcgacct
tactggtgggtccaagaaactcagatttacccaaatcactcaagtccatgccttgaacag
ttccctactacatgtgaaacaggtccaggaagtccatctggccatgcaatgggcgcatcc
tgtgtctggtatgtcatggtaaccgctgccctgagccacactgtctgtgggatggataag
ttctctatcactctgcacagactgacctggtcatttctttggagtgttttttggttgatt
caaatcagtgtctgcatctccagagtattcatagcaacacattttcctcatcaagttatt
cttggagtaattggtggcatgctggtggcagaggcctttgaacacactccaggcatccaa
acggccagtctgggcacatacctgaagaccaacctctttctcttcctgtttgcagttggc
ttttacctgcttcttagggtgctcaacattgacctgctgtggtccgtgcccatagccaaa
aagtggtgtgctaaccccgactggatccacattgacaccacgccttttgctggactcgtg
agaaaccttggggtcctctttggcttgggctttgcaatcaactcagagatgttcctcctg
agctgccgagggggaaataactacacactgagcttccggttgctctgtgccttgacctca
ttgacaatactgcagctctaccatttcctccagatcccgactcacgaagagcatttattt
tatgtgctgtctttttgtaaaagtgcatccattcccctaactgtggttgctttcattccc
tactctgttcatatgttaatgaaacaaagcggaaagaagagtcagtag

KEGG   Homo sapiens (human): 92579
Entry
92579             CDS       T01001                                 
Symbol
G6PC3, SCN4, UGRP
Name
(RefSeq) glucose-6-phosphatase catalytic subunit 3
  KO
K01084  glucose-6-phosphatase [EC:3.1.3.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00052  Galactose metabolism
hsa00500  Starch and sucrose metabolism
hsa01100  Metabolic pathways
hsa04068  FoxO signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04910  Insulin signaling pathway
hsa04920  Adipocytokine signaling pathway
hsa04922  Glucagon signaling pathway
hsa04931  Insulin resistance
hsa04973  Carbohydrate digestion and absorption
Network
nt06017  Glycogen metabolism
  Element
N00718  Glycogen degradation
Disease
H00100  Neutropenic disorders
H00939  Darsun syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    92579 (G6PC3)
   00052 Galactose metabolism
    92579 (G6PC3)
   00500 Starch and sucrose metabolism
    92579 (G6PC3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    92579 (G6PC3)
   04151 PI3K-Akt signaling pathway
    92579 (G6PC3)
   04152 AMPK signaling pathway
    92579 (G6PC3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    92579 (G6PC3)
   04922 Glucagon signaling pathway
    92579 (G6PC3)
   04920 Adipocytokine signaling pathway
    92579 (G6PC3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    92579 (G6PC3)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    92579 (G6PC3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.9  glucose-6-phosphatase
     92579 (G6PC3)
SSDB
Motif
Pfam: PAP2
Other DBs
NCBI-GeneID: 92579
NCBI-ProteinID: NP_612396
OMIM: 611045
HGNC: 24861
Ensembl: ENSG00000141349
UniProt: Q9BUM1
LinkDB
Position
17:44070673..44076344
AA seq 346 aa
MESTLGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWI
SLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAPAQVHQFPSSCETGPGSPSGHCMITGA
ALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGA
VLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLFTLGLDLSWSISLAFKWCERPEW
IHVDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAQLGNGQKIACLVLAMGLLGPLDWL
GHPPQISLFYIFNFLKYTLWPCLVLALVPWAVHMFSAQEAPPIHSS
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggagtccacgctgggcgcgggcatcgtgatagccgaggcgctacagaaccagctagcc
tggctggagaacgtgtggctctggatcacctttctgggcgatcccaagatcctctttctg
ttctacttccccgcggcctactacgcctcccgccgtgtgggcatcgcggtgctctggatc
agcctcatcaccgagtggctcaacctcatcttcaagtggtttctttttggagacaggccc
ttttggtgggtccatgagtctggttactacagccaggctccagcccaggttcaccagttc
ccctcttcttgtgagactggtccaggcagcccttctggacactgcatgatcacaggagca
gccctctggcccataatgacggccctgtcttcgcaggtggccactcgggcccgcagccgc
tgggtaagggtgatgcctagcctggcttattgcaccttccttttggcggttggcttgtcg
cgaatcttcatcttagcacatttccctcaccaggtgctggctggcctaataactggcgct
gtcctgggctggctgatgactccccgagtgcctatggagcgggagctaagcttctatggg
ttgactgcactggccctcatgctaggcaccagcctcatctattggaccctctttacactg
ggcctggatctttcttggtccatcagcctagccttcaagtggtgtgagcggcctgagtgg
atacacgtggatagccggccctttgcctccctgagccgtgactcaggggctgccctgggc
ctgggcattgccttgcactctccctgctatgcccaggtgcgtcgggcacagctgggaaat
ggccagaagatagcctgccttgtgctggccatggggctgctgggccccctggactggctg
ggccacccccctcagatcagcctcttctacattttcaatttcctcaagtacaccctctgg
ccatgcctagtcctggccctcgtgccctgggcagtgcacatgttcagtgcccaggaagca
ccgcccatccactcttcctga

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