Homo sapiens (human): 25778
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Entry
25778 CDS
T01001
Symbol
DSTYK, CAKUT1, DustyPK, HDCMD38P, RHDNS1, RIP5, RIPK5, SPG23
Name
(RefSeq) dual serine/threonine and tyrosine protein kinase
KO
K16288
dual serine/threonine and tyrosine protein kinase [EC:
2.7.12.1
]
Organism
hsa
Homo sapiens (human)
Disease
H00266
Hereditary spastic paraplegia
H01867
Congenital anomalies of kidney and urinary tract
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
25778 (DSTYK)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.1 dual-specificity kinase
25778 (DSTYK)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: Other
Other
25778 (DSTYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Haspin_kinase
Kinase-like
Kdo
Motif
Other DBs
NCBI-GeneID:
25778
NCBI-ProteinID:
NP_056190
OMIM:
612666
HGNC:
29043
Ensembl:
ENSG00000133059
UniProt:
Q6XUX3
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All DBs
Position
1:complement(205142505..205211702)
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AA seq
929 aa
AA seq
DB search
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN
HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD
CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH
QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL
VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER
SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK
ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI
VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL
ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM
LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF
AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR
GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY
NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL
KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWY
ICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLG
IVQPMLQGIMNRLCKSNSEQPNRGLDDST
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgacggggtgccatggggcagcgagcccgtctcgggtcccggccccggcggc
ggcggaatgatccgcgagctgtgccggggcttcggccgctaccgccgctacctgggacgg
ctgcgacagaacctgcgcgagacccagaagttcttccgcgacatcaagtgctcccacaac
cacacttgtctctcctccctcacgggcggcggcggggccgagcgcggccctgcaggcgat
gtcgccgaaaccgggctgcaggcgggccaactgagctgcatttccttcccacctaaggaa
gagaagtacctccagcagattgtggactgcctcccttgcatactgatcctcggccaggat
tgtaacgtcaagtgccagctgttgaatctgctgttgggggtgcaggtgcttcccaccacc
aagctgggcagtgaggagagctgtaagcttcggcgcctccgcttcacctatgggactcag
actcgggtcagcctggcgctccctggacagtatgaactagtgcacacgctggttgctcat
cagggcaactgggagaccatccctgaggaggatctggaggtccaagagaacaatgaggat
gctgctcatgttttagcggaactggaggtaacgatgcaccatgctctcttacaggaagtg
gacgttgtggtagcaccatgccaaggcctccggcccacagtggatgttctgggtgacttg
gtgaatgatttcttgcctgtgataacctatgcactccacaaagatgaactctctgagagg
gatgagcaagagcttcaggaaatccgaaagtatttctcctttcctgtattctttttcaaa
gtgccgaaactgggctcggagataatagactcctcaaccaggagaatggagagcgaaaga
tcaccgctttatcgccagctaattgacctgggctatctgagcagcagtcactggaactgt
ggggctcctggccaggatactaaagctcagagcatgttggtggaacagagtgaaaagctg
agacacttgagcacattttctcaccaggtgttacagactcgcctggtggatgcagccaag
gccctgaacctggtgcactgccactgccttgacatctttattaaccaggcatttgacatg
cagcgggacctgcagatcactcccaaacgtctggaatatactcgaaaaaaggagaatgag
ttgtatgaatcattgatgaatattgccaaccgaaagcaggaggaaatgaaggatatgatt
gttgagacacttaataccatgaaggaggaacttctggatgatgctactaacatggagttt
aaagacgtcattgtccctgagaatggagaaccagtaggcaccagagagatcaaatgctgc
atccgacagatccaggaactcatcatctcccgacttaatcaggcagtggctaataagctg
atcagctcagtggattacctgagggaaagcttcgtcggaaccctggaacgatgtctgcag
agcctggagaagtctcaggatgtctcagttcacatcaccagtaattatctcaaacagatc
ttaaatgctgcctatcatgttgaagtcacgtttcactcagggtcgtcagttacaaggatg
ctatgggagcaaatcaaacagatcatccagcgcatcacatgggtgagcccacctgccatc
actctggaatggaagaggaaggtggcccaggaagccattgagagcctcagcgcctccaaa
ttggctaagagcatttgcagccaattccggactcggctcaatagttcccacgaggctttt
gcagcctccttgcggcagctggaagctggccactcaggccggttagagaaaacggaagat
ctatggctgagggttcggaaagatcatgctccccgcctggcccgcctttctctggaaagc
tgttctttacaggatgtcttgcttcatcgtaaacctaaactgggacaggaactgggccgg
ggccagtatggtgtggtatacctgtgtgacaactggggaggacacttcccttgtgccctc
aaatcagttgtccctccagatgagaagcactggaatgatctggctttggaatttcactat
atgaggtctctgccgaagcatgagcgattggtggatctccatggttcagtcattgactac
aactatggtggtggctccagcattgctgtgctcctcattatggagcggctacaccgggat
ctctacacagggctgaaggctgggctgaccctggagacacgtttgcagatagcactagat
gtggtggagggaatccgcttcctgcacagccagggacttgtccatcgtgatatcaaactg
aaaaatgtgctgctggataagcagaaccgtgccaagatcactgacttaggattctgcaag
ccagaggccatgatgtcaggcagcattgtggggacaccaatccatatggcccctgaactt
ttcacagggaagtacgataattccgtggatgtctacgcttttggaattcttttctggtat
atctgctcaggctctgtcaagctccctgaggcatttgagaggtgtgctagcaaagaccat
ctctggaacaatgtgcggaggggggctcgcccagaacgtcttcctgtgtttgatgaggag
tgctggcagttgatggaagcctgttgggatggcgaccccttgaagaggcctctcttgggc
attgtccagcccatgctccagggcatcatgaatcggctctgcaagtccaattctgagcag
ccaaacagaggactagatgattctacttga
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