Homo sapiens (human): 25885
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Entry
25885 CDS
T01001
Symbol
POLR1A, A190, AFDCIN, HLD27, RPA1, RPA190, RPA194, RPO1-4, RPO14
Name
(RefSeq) RNA polymerase I subunit A
KO
K02999
DNA-directed RNA polymerase I subunit RPA1 [EC:
2.7.7.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03020
RNA polymerase
Disease
H00679
Hypomyelinating leukodystrophy
H01376
Acrofacial dysostosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03020 RNA polymerase
25885 (POLR1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
hsa03021
]
25885 (POLR1A)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.6 DNA-directed RNA polymerase
25885 (POLR1A)
Transcription machinery [BR:
hsa03021
]
Eukaryotic type
RNA polymerase I system
RNA polymerase I
Core subunits
25885 (POLR1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RNA_pol_Rpb1_5
RNA_pol_Rpb1_2
RNA_pol_Rpb1_3
RNA_pol_Rpb1_1
RNA_pol_Rpb1_4
NOA36
Motif
Other DBs
NCBI-GeneID:
25885
NCBI-ProteinID:
NP_056240
OMIM:
616404
HGNC:
17264
Ensembl:
ENSG00000068654
UniProt:
O95602
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(86020216..86105886)
Genome browser
AA seq
1720 aa
AA seq
DB search
MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADS
KEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLL
LCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAH
VKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDS
EPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLD
FLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTT
DEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQI
LEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQEL
RQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCR
HVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQ
SELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRG
LTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKET
PRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTC
LARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYD
EVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQS
GAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIK
PPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYG
EDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHP
NTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAA
ACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKW
QRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIK
TPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQ
FLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNA
GELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEEN
DDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMER
RVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGIT
RCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRV
IEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQF
LKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
NT seq
5163 nt
NT seq
+upstream
nt +downstream
nt
atgttgatctccaagaacatgccctggcggcggctgcagggcatttccttcgggatgtat
tcggctgaagagctcaagaaattaagtgttaaatccattacgaaccctcgatacctggac
agcctggggaacccatcggcaaacggcctgtacgatttagctttgggccctgcagattcc
aaagaggtgtgctccacctgcgtgcaggacttcagcaactgttctgggcacctgggccac
attgagctcccactcacagtgtataaccctctcctcttcgataagctgtacctgctgctt
cggggctcttgtttaaactgccacatgctgacttgtccccgggccgtgattcacctctta
ctctgccagctgagggttctggaagtcggggccctacaagcagtctacgagcttgagaga
attctgaacaggtttctggaagaaaatcccgatccctctgcctctgaaattcgggaggaa
ttagaacaatacacaactgaaattgtgcagaacaacctcctggggtcccagggcgcacat
gtaaagaacgtgtgtgagagcaagagcaagctcattgctctcttctggaaggcacatatg
aatgctaagcgctgtccccactgcaagaccgggcgatccgttgtccgaaaggaacacaac
agcaagttgactatcacgtttccagccatggtgcacaggacagctggccagaaggactct
gagcccctgggaattgaggaagctcagataggaaaacgaggatacttaacacccaccagt
gcccgcgaacacctttctgccctgtggaagaatgaaggattctttctgaactaccttttt
tcgggaatggatgatgatggtatggaatccagattcaatcccagtgtgttctttctagat
ttcttggtggtgccgccctcaaggtatcgcccagtcagtcgcctaggagaccagatgttt
actaatggccagacggtgaacttgcaggctgtcatgaaggatgtagttctgattcgaaaa
cttctggcattgatggcccaagaacagaagttgccagaggaagtggccacacccactaca
gatgaggaaaaagactctttgattgctattgaccgatcctttttgagtacacttccaggc
cagtccctcatagacaaactttacaacatttggattcgccttcagagccacgtcaatatt
gtgtttgatagcgagatggacaaactaatgatggacaagtacccaggcattaggcagatc
ctggagaagaaagaaggcctgttccgaaaacacatgatgggaaagcgagtggactacgct
gcgcgctcagtcatctgcccagacatgtacatcaacaccaacgaaattggaattcccatg
gtgtttgccacaaaactgacctacccacagccagttaccccatggaatgttcaggaactt
aggcaagcggtcatcaacggccctaatgtgcacccaggagcctccatggtcatcaatgag
gacggcagccgcacagccctgagcgctgtggacatgacccagcgagaggccgtggccaag
cagcttctgaccccagccacgggggcacctaagccccaggggacaaaaattgtgtgccgg
catgtgaagaatggggacattctgctactgaaccgacagcccacactgcacagaccctcc
atccaggcccaccgtgcccgcatcctgcctgaagagaaagtgctgcggctccactatgcc
aactgcaaggcctataatgccgactttgatggagacgagatgaatgcccatttcccccag
agtgagctgggccgggccgaggcctacgtcctggcctgcactgatcagcagtaccttgtt
cccaaggatggccaaccattggcgggactgatccaggatcacatggtttcaggggcaagc
atgactactcggggttgctttttcacccgggagcactatatggagctggtgtaccgagga
ctcacggacaaagtggggcgcgtgaagctcctttctccttccatcctgaagccctttccg
ctgtggacaggaaaacaggttgtgtcaacgctgctcataaatataatcccagaggaccac
atcccactgaacttatctggaaaggcgaaaatcactgggaaagcctgggtgaaggaaact
cctcgatccgttcctggctttaaccctgactcgatgtgcgagtcccaggtgatcatcagg
gaaggggagctgctctgcggagtgctggacaaggcgcactatgggagctccgcctacggc
ctggtccactgctgctatgagatctatggaggcgagaccagcggcaaggttctaacctgc
ctggcccgcctcttcaccgcctacctgcagctctacagaggcttcaccttgggcgtggaa
gacattttggtgaagccaaaggcagatgtcaagaggcaacgtatcattgaagaatccacc
cactgcgggccccaggctgtcagggctgcattaaacctgccagaagccgcatcatatgat
gaggtccgaggaaaatggcaggatgcccatctgggcaaggaccagagggattttaacatg
attgatctgaagttcaaggaggaagtgaaccattacagcaatgagattaacaaggcatgc
atgccttttggcctacacagacagttcccagagaacagcctgcagatgatggtgcagtcg
ggagccaaaggttcaactgtgaacacgatgcagatctcgtgcctgctgggccagattgaa
ctggaaggtcggagacccccgctgatggcgtctggcaagtcactgccctgctttgagcct
tatgagttcacccccagggctggtggctttgtcactggcaggttcctcaccggcatcaaa
cctcctgagttcttcttccactgcatggcaggacgagagggcctggtggacactgctgtg
aaaaccagccgctcaggctatctccaaaggtgcatcatcaagcacctagaggggctggtc
gtgcagtatgatctcacggtccgtgacagtgacggcagtgtggtgcagttcctgtatggg
gaggatggcctggacatccccaagacacagttcctgcagcccaagcagttccccttcctg
gccagcaactacgaggtgataatgaaatcacagcatctccatgaagttttatccagagca
gatcccaaaaaagctctccaccacttcagagctatcaaaaaatggcaaagcaagcacccc
aacaccctgctgagaagaggcgccttcttgagttattcccagaaaattcaggaagctgtg
aaagccctgaaacttgagagtgaaaaccgcaatggccgcagccctgggactcaggagatg
ctgaggatgtggtatgagttggatgaggaaagccgaaggaaataccagaagaaggcggcc
gcttgtcctgaccccagtctgtctgtctggcgtcctgacatctactttgcatcagtgtca
gaaacatttgaaacaaaggttgatgactacagtcaagagtgggcagctcaaacagagaag
agttatgagaaatcagagctttctctcgacaggttgaggaccttgctgcagctgaagtgg
cagcgctcactgtgtgagccgggcgaggctgtgggcctgctggctgcccagagcatcgga
gagccctccacccagatgaccctcaacaccttccactttgcaggcagaggcgagatgaac
gtcaccctgggcattccaaggttgcgggagattctcatggtggccagcgccaacatcaag
acacccatgatgagcgtgcccgtgctcaacaccaagaaagccctgaagagagtgaaaagc
ctgaagaagcaactcaccagggtgtgcttgggggaggtgttgcagaaaattgacgtccag
gagtccttctgtatggaagaaaaacagaacaaattccaggtgtaccagctgcggtttcag
ttcctgccacatgcatattaccagcaggagaagtgcctgagacccgaggacatcctgcgc
ttcatggaaacaagattctttaaacttctgatggaatccatcaaaaagaagaataataaa
gcatcagctttcaggaacgtaaacactcgaagagctacacagcgggatctggacaacgct
ggggagttggggaggagtcggggagagcaggagggtgatgaggaagaggaggggcacatt
gtggatgctgaagctgaggagggggacgccgatgcctctgatgccaaacgcaaggagaag
caggaggaggaggttgattatgagagtgaggaagaggaggagagggagggcgaggagaac
gacgatgaagacatgcaggaggaacgaaatccccacagggaaggtgctcgaaagacccaa
gagcaagatgaagaggtgggcttaggcactgaggaggacccgtcccttcccgccctcctg
acgcagccccggaaacccacccacagccaggagccccaggggcccgaggccatggagcgc
cgggtccaggctgtgcgtgagatccacccgttcatagatgactaccagtacgacaccgag
gagagcctgtggtgccaggtgacagtgaagctccctctgatgaagatcaactttgacatg
agctccctggtagtatctttggcccatggtgccgtcatctatgcgaccaagggcatcact
cggtgcctcctgaatgaaacaaccaacaataagaacgagaaggagcttgtgctaaacaca
gaaggaatcaacctcccagagctattcaagtatgcagaggtcctggatctgcgccgcctc
tactccaacgacatccacgccatagccaacacgtatggcattgaggccgcgctgcgggtg
atcgagaaggagatcaaggatgtgtttgccgtgtatggcatcgcggtcgaccctcgccat
ctctccctggttgctgattatatgtgcttcgagggtgtttacaagccactgaatcgcttt
gggatccggtcaaactcttccccgctacagcagatgacatttgaaaccagcttccagttt
ctgaagcaagccaccatgctgggatcccacgatgagctgaggtctccttctgcctgcctt
gtggtcgggaaggtcgtcaggggcgggacaggcctgttcgagctcaagcagcctctgaga
tag
DBGET
integrated database retrieval system
