Homo sapiens (human): 25930
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Entry
25930 CDS
T01001
Symbol
PTPN23, HD-PTP, HDPTP, NEDBASS, PTP-TD14
Name
(RefSeq) protein tyrosine phosphatase non-receptor type 23
KO
K18040
tyrosine-protein phosphatase non-receptor type 23 [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Disease
H02470
Neurodevelopmental disorder with structural brain abnormalities
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
25930 (PTPN23)
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
hsa03037
]
25930 (PTPN23)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
25930 (PTPN23)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
25930 (PTPN23)
Cilium and associated proteins [BR:
hsa03037
]
Primary cilia and associated proteins
Other primary cilia associated proteins
25930 (PTPN23)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRO1
Y_phosphatase
ALIX_LYPXL_bnd
PTP-SAK
Y_phosphatase3
Tc-R-P
ORF6C
DSPc
PTP-NADK
PTPlike_phytase
Motif
Other DBs
NCBI-GeneID:
25930
NCBI-ProteinID:
NP_056281
OMIM:
606584
HGNC:
14406
Ensembl:
ENSG00000076201
UniProt:
Q9H3S7
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:47381021..47413435
Genome browser
AA seq
1636 aa
AA seq
DB search
MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPR
DFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYN
LGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNL
MLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKL
VQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRF
TMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKL
VPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQ
LMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQA
GAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAAL
PTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKK
LFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVA
SYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKKPPPRP
TAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSST
GPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQ
HGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPN
PTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQ
PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYP
GPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTP
SPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPL
LQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRGQLGDVGALDTVWRELQD
AQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLV
ATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLAL
SSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLH
QRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKL
HLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQA
TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKE
EPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRATRPS
DDPLSLLDPLWTLNKT
NT seq
4911 nt
NT seq
+upstream
nt +downstream
nt
atggaggccgtgccccgcatgcccatgatctggctggacctgaaggaggccggtgacttt
cacttccagccagctgtgaagaagtttgtcctgaagaattatggagagaacccagaagcc
tacaatgaagaactgaagaagctggagttgctcagacagaatgctgtccgtgtcccacga
gactttgagggctgtagtgtcctccgcaagtacctcggccagcttcattacctgcagagt
cgggtccccatgggctcgggccaggaggccgctgtccctgtcacctggacagagatcttc
tcaggcaagtctgtggcccatgaggacatcaagtacgagcaggcctgtattctctacaac
cttggagcgctgcactccatgctgggggccatggacaagcgggtgtctgaggagggcatg
aaggtctcctgtacccatttccagtgcgcagccggcgccttcgcctacctacgggagcac
ttccctcaagcctacagcgtcgacatgagccgccagatccttacgctcaacgtcaacctc
atgctgggccaggctcaggagtgcctcctggagaagtcgatgttggacaacaggaagagc
tttctggtggcccgcatcagtgcacaggtggtagattactacaaggaggcatgccgggcc
ttggagaaccccgacactgcctcactgctgggccggatccagaaggactggaagaaactt
gtgcagatgaagatctactacttcgcagccgtggctcatctgcacatgggaaagcaggcc
gaggagcagcagaagttcggggagcgggttgcatacttccagagcgccctggacaagctc
aatgaagccatcaagttggccaagggccagcctgacactgtgcaagacgcgcttcgcttc
actatggatgtcattgggggaaagtacaattctgccaagaaggacaacgacttcatttac
catgaggctgtcccagcattggacactcttcagcctgtaaaaggagcccccttggtgaag
cccttgccagtgaaccccacagacccagctgttacaggccctgacatctttgccaaactg
gtacccatggctgcccacgaggcctcgtcactgtacagtgaggagaaggccaagctgctc
cgggagatgatggccaagattgaggacaagaatgaggtcctggaccagttcatggattca
atgcagttggatcccgagacggtggacaaccttgatgcctacagccacatcccaccccag
ctcatggagaagtgcgcggctctcagcgtccggcccgacactgtcaggaaccttgtacag
tccatgcaagtgctgtcaggtgtgttcacggatgtggaggcttccctgaaggacatcaga
gatctgttggaggaggatgagctgctagagcagaagtttcaggaggcggtgggccaggca
ggggccatctccatcacctccaaggctgagctggcagaggtgaggcgagaatgggccaag
tacatggaagtccatgagaaggcctccttcaccaacagtgagctgcaccgtgccatgaac
ctgcacgtcggcaacctgcgcctgctcagcgggccgcttgaccaggtccgggctgccctg
cccacaccggccctctccccagaggacaaggccgtgctgcaaaacctaaagcgcatcctg
gctaaggtgcaggagatgcgggaccagcgcgtgtccctggagcagcagctgcgtgagctt
atccagaaagatgacatcactgcctcgctggtcaccacagaccactcagagatgaagaag
ttgttcgaggagcagctgaaaaagtatgaccagctgaaggtgtacctggagcagaacctg
gccgcccaggaccgtgtcctctgtgcactgacagaggccaacgtgcagtacgcagccgtg
cggcgggtactcagcgacttggaccaaaagtggaactccacgctgcagaccctggtggcc
tcgtatgaagcctatgaggacctgatgaagaagtcgcaggagggcagggacttctacgca
gatctggagagcaaggtggctgctctgctggagcgcacgcagtccacctgccaggcccgc
gaggctgcccgccagcagctcctggacagggagctgaagaagaagccgccgccacggccc
acagccccaaagccgctgctgccccgcagggaggagagtgaggcagtggaagcaggagac
ccccctgaggagctgcgcagcctcccccctgacatggtggctggcccacgactgcctgac
accttcctgggaagtgccaccccgctccactttcctcccagccccttccccagctccaca
ggcccaggaccccactatctctcaggccccttgccccctggtacctactcgggccccacc
cagctgatacagcccagggccccagggccccatgcaatgcccgtagcacctgggcctgcc
ctctacccagcccctgcctacacaccggagctgggccttgtgccccgatcctccccacag
catggcgtggtgagcagtccctatgtgggggtagggccggccccaccagttgcaggtctc
ccctcggccccacctcctcaattctcaggccccgagttggccatggcggttcggccagcc
accaccacagtagatagcatccaggcgcccatccccagccacacagccccacggccaaac
cccacccctgctcctcccccgccctgcttccctgtgcccccaccgcagccactgcccacg
ccttacacctaccctgcaggggctaagcaacccatcccggcacagcaccacttctcttct
gggatccccgcaggttttccagccccaaggattgggccccagccccagccccatcctcag
ccccatccttcacaagcgtttgggcctcagcccccacagcagccccttccactccagcat
ccacatctcttcccaccccaggccccaggactcctacccccacaatccccctacccctat
gcccctcagcctggggtcctggggcagccgccaccccccctacacacccagctctaccca
ggtcccgctcaagaccctctgccagcccactcaggggctctgcctttccccagccctggg
ccccctcagcctccccatcccccactggcatatggtcctgccccttctaccagacccatg
ggcccccaggcagcccctcttaccattcgagggccctcgtctgctggccagtccacccct
agtccccacctggtgccttcacctgccccatctccagggcctggtccggtaccccctcgc
cccccagcagcagaaccacccccttgcctgcgccgaggcgccgcagctgcagacctgctc
tcctccagcccggagagccagcatggcggcactcagtctcctgggggtgggcagcccctg
ctgcagcccaccaaggtggatgcagctgagggtcgtcggccgcaggccctgcggctgatt
gagcgggacccctatgagcatcctgagaggctgcggcagttgcagcaggagctggaggcc
tttcggggtcagctgggggatgtgggagctctggacactgtctggcgagagctgcaagat
gcgcaggaacatgatgcccgaggccgttccatcgccattgcccgctgctactcactgaag
aaccggcaccaggatgtcatgccctatgacagtaaccgtgtggtgctgcgctcaggcaag
gatgactacatcaatgccagctgcgtggaggggctctccccatactgccccccgctagtg
gcaacccaggccccactgcctggcacagctgctgacttctggctcatggtccatgagcag
aaagtgtcagtcattgtcatgctggtttctgaggctgagatggagaagcaaaaagtggca
cgctacttccccaccgagaggggccagcccatggtgcacggtgccctgagcctggcattg
agcagcgtccgcagcaccgaaacccatgtggagcgcgtgctgagcctgcagttccgagac
cagagcctcaagcgctctcttgtgcacctgcacttccccacttggcctgagttaggcctg
cccgacagccccagcaacttgctgcgcttcatccaggaggtgcacgcacattacctgcat
cagcggccgctgcacacgcccatcattgtgcactgcagctctggtgtgggccgcacggga
gcctttgcactgctctatgcagctgtgcaggaggtggaggctgggaacggaatccctgag
ctgcctcagctggtgcggcgcatgcggcagcagagaaagcacatgctgcaggagaagctg
cacctcaggttctgctatgaggcagtggtgagacacgtggagcaggtcctgcagcgccat
ggtgtgcctcctccatgcaaacccttggccagtgcaagcatcagccagaagaaccacctt
cctcaggactcccaggacctggtcctcggtggggatgtgcccatcagctccatccaggcc
accattgccaagctcagcattcggcctcctggggggttggagtccccggttgccagcttg
ccaggccctgcagagcccccaggcctcccgccagccagcctcccagagtctaccccaatc
ccatcttcctccccgccccccctttcctccccactacctgaggctccccagcctaaggag
gagccgccagtgcctgaagcccccagctcggggcccccctcctcctccctggaattgctg
gcctccttgaccccagaggccttctccctggacagctccctgcggggcaaacagcggatg
agcaagcataactttctgcaggcccataacgggcaagggctgcgggccacccggccctct
gacgaccccctcagccttctggatccactctggacactcaacaagacctga
DBGET
integrated database retrieval system
