Homo sapiens (human): 26259
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Entry
26259 CDS
T01001
Symbol
FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Name
(RefSeq) F-box and WD repeat domain containing 8
KO
K10264
F-box and WD-40 domain protein 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
26259 (FBXW8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
26259 (FBXW8)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
SCF complex
Target recognizing subunit (F-box)
26259 (FBXW8)
Cul7 complex
Target recognizing subunit
26259 (FBXW8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
F-box-like
F-box
WDR54
Motif
Other DBs
NCBI-GeneID:
26259
NCBI-ProteinID:
NP_699179
OMIM:
609073
HGNC:
13597
Ensembl:
ENSG00000174989
Pharos:
Q8N3Y1
(Tbio)
UniProt:
Q8N3Y1
Structure
PDB
PDBj
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All DBs
Position
12:116910950..117031148
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AA seq
598 aa
AA seq
DB search
MDDYSLDEFRRRWQEELAQAQAPKKRRRPEAAERRARRPEVGSGRGEQASGDPALAQRLL
EGAGRPPAARATRAEGQDVASRSRSPLAREGAGGGEQLVDQLIRDLNEMNDVPFFDIQLP
YELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSCWKLI
FQECRAKEHMLRTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTW
DYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLNIWDLRTGKYPVHRFEHDA
RIQALALSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVPKLVQYLEIVPETRRYPVA
VAAAGDLMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGVQGLGWVYEGSKILVYSLE
AGRRLLKLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSA
VQMDDWKIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRN
ADLDSFTTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAMATHYYDLALAFPYNHV
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atggacgactacagcctggatgagttccgtcggcgctggcaggaggagctggcgcaggcc
caggcgccgaagaagcggcgacggcccgaggctgccgagaggcgggctcggcggccggag
gtgggctccgggcgcggcgaacaggcctcgggggacccggcgctggcccagcgtctcctg
gagggcgcggggaggcccccggcggcgcgggcgactcgggccgaggggcaggacgtagcg
agccgctcacgttctcctctggcccgcgagggcgccgggggcggggagcagctggtggac
cagctcatccgcgacctgaatgaaatgaatgatgtgcctttctttgatatccaactgcct
tacgaattggcaatcaatatatttcagtatctggacaggaaagaactaggaagatgtgca
caggtgagcaagacgtggaaggtgattgcagaggatgaggtgctgtggtacaggctgtgc
cagcaggaagggcaccttccggatagcagcatctctgactattcttgctggaagctcatc
ttccaagagtgccgagccaaggaacacatgttacgaaccaactggaagaatcgcaaaggt
gccgtgagcgagctggagcatgttcctgacacagttttgtgtgatgtgcattctcacgat
ggtgtggtcattgcgggatatacatcaggggatgtgagagtgtgggacacccgcacctgg
gactacgtagcccccttcctggaatcagaggacgaggaggatgagcctggaatgcagcca
aatgtctcctttgtgaggataaacagctcgttggcagtagcagcttatgaggatgggttt
cttaatatttgggatttaaggaccggaaagtaccctgttcatcgttttgagcacgatgca
agaatacaggcactagccctcagccaggacgatgcaaccgtggccacagcttctgctttt
gatgtcgtgatgttatcccccaatgaggaggggtactggcagatagctgcggaatttgaa
gttccgaaactggttcagtaccttgaaatagttccagaaaccagaaggtaccctgtggca
gtagccgctgctggagatctgatgtacctgctcaaagccgaagactccgccagaaccctc
ctttacgcccacggcccgcctgtcacatgtctagacgtctcggccaaccaagttgctttt
ggtgtacagggtctgggatgggtgtacgaaggaagcaagatcctggtgtatagcctggaa
gcaggacgccgcctcttgaagctgggtaacgttctccgtgacttcacgtgtgtcaacctc
agcgacagccctcccaacctcatggtcagtggcaacatggacgggagggtgaggatccac
gacctccgcagtggtaacatcgccctgtcgctctccgcccatcagctcagggtctctgct
gtgcagatggatgactggaagatcgtcagtggaggcgaggaaggcctggtgtccgtgtgg
gattatcggatgaaccagaagctgtgggaggtgtattccgggcacccggtgcagcacatc
tcattcagcagccacagcctcatcacggccaacgtgccttaccagacggtaatgcgaaac
gccgacctggacagcttcactactcacaggagacaccgggggctgatccgcgcctatgag
tttgcggtggaccagctggccttccagagccctctccctgtctgccgttcatcctgtgac
gccatggccactcactactacgacctcgcactggcctttccctataaccatgtttag
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