Homo sapiens (human): 26524
Help
Entry
26524 CDS
T01001
Symbol
LATS2, KPM
Name
(RefSeq) large tumor suppressor kinase 2
KO
K08791
serine/threonine-protein kinase LATS1/2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04392
Hippo signaling pathway - multiple species
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
26524 (LATS2)
04392 Hippo signaling pathway - multiple species
26524 (LATS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
26524 (LATS2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
26524 (LATS2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
NDR family
26524 (LATS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
UBA_7
ABC1
UBA
APH
Haspin_kinase
Pox_ser-thr_kin
Kinase-like
Kdo
Motif
Other DBs
NCBI-GeneID:
26524
NCBI-ProteinID:
NP_055387
OMIM:
604861
HGNC:
6515
Ensembl:
ENSG00000150457
UniProt:
Q9NRM7
Structure
PDB
LinkDB
All DBs
Position
13:complement(20973036..21061586)
Genome browser
AA seq
1088 aa
AA seq
DB search
MRPKTFPATTYSGNSRQRLQEIREGLKQPSKSSVQGLPAGPNSDTSLDAKVLGSKDATRQ
QQQMRATPKFGPYQKALREIRYSLLPFANESGTSAAAEVNRQMLQELVNAGCDQEMAGRA
LKQTGSRSIEAALEYISKMGYLDPRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTGDSF
ASYHQLSGTPYEGPSFGADGPTALEEMPRPYVDYLFPGVGPHGPGHQHQHPPKGYGASVE
AAGAHFPLQGAHYGRPHLLVPGEPLGYGVQRSPSFQSKTPPETGGYASLPTKGQGGPPGA
GLAFPPPAAGLYVPHPHHKQAGPAAHQLHVLGSRSQVFASDSPPQSLLTPSRNSLNVDLY
ELGSTSVQQWPAATLARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPGPPG
KAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPA
AEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLRSKSEQYDLDSLCAGM
EQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPY
AFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKR
AKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDIL
AEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIE
SVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSD
LWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVG
VILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLG
RNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTK
AWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAESSDLESSDLVDQT
EGCQPVYV
NT seq
3267 nt
NT seq
+upstream
nt +downstream
nt
atgaggccaaagacttttcctgccacgacttattctggaaatagccggcagcgactgcaa
gagattcgtgaggggttaaaacagccatccaagtcttcggttcaggggctacccgcagga
ccaaacagtgacacttccctggatgccaaagtcctggggagcaaagatgccaccaggcag
cagcagcagatgagagccaccccaaagttcggaccttatcagaaagccttgagggaaatc
agatattccttgttgccttttgctaatgaatcgggcacctctgcagctgcagaagtgaac
cggcaaatgctgcaggaactggtgaacgcaggatgcgaccaggagatggctggccgagct
ctcaagcagactggcagcaggagcatcgaggccgccctggagtacatcagcaagatgggc
tacctggacccgaggaatgagcagattgtgcgggtcattaagcagacctccccaggaaag
gggctcatgccaaccccagtgacgcggaggcccagcttcgaaggaaccggcgattcgttt
gcgtcctaccaccagctgagcggtaccccctacgagggcccaagcttcggcgctgacggc
cccacggcgctggaggagatgccgcggccgtacgtggactaccttttccccggagtcggc
ccccacgggcccggccaccagcaccagcacccacccaagggctacggtgccagcgtagag
gcagcaggggcacacttcccgctgcagggcgcgcactacgggcggccgcacctgctggtg
cctggggaacccctgggctacggagtgcagcgcagcccctccttccagagcaagacgccg
ccggagaccgggggttacgccagcctgcccacgaagggccagggaggaccgccaggcgcc
ggcctcgctttcccaccccctgccgccgggctctacgtgccgcacccacaccacaagcag
gccggtcccgcggcccaccagctgcatgtgctgggctcccgcagccaggtgttcgccagc
gacagccccccgcagagcctgctcactccctcgcggaacagcctcaacgtggacctgtat
gaattgggcagcacctccgtccagcagtggccggctgccaccctggcccgccgggactcc
ctgcagaagccgggcctggaggcgccgccgcgcgcgcacgtggccttccggcctgactgc
ccagtgcccagcaggaccaactccttcaacagccaccagccgcggcccggtccgcctggc
aaggccgagccctccctgcccgcccccaacaccgtgacggctgtcacggccgcgcacatc
ttgcacccggtgaagagcgtgcgtgtgctgaggccggagccgcagacggctgtggggccc
tcgcaccccgcctgggtgcccgcgcctgccccggcccccgcccccgcccccgccccggct
gcggagggcttggacgccaaggaggagcatgccctggcgctgggcggcgcaggcgccttc
ccgctggacgtggagtacggaggcccagaccggaggtgcccgcctccgccctacccgaag
cacctgctgctgcgcagcaagtcggagcagtacgacctggacagcctgtgcgcaggcatg
gagcagagcctccgtgcgggccccaacgagcccgagggcggcgacaagagccgcaaaagc
gccaagggggacaaaggcggaaaggataaaaagcagattcagacctctcccgttcccgtc
cgcaaaaacagcagagacgaagagaagagagagtcacgcatcaagagctactcgccatac
gcctttaagttcttcatggagcagcacgtggagaatgtcatcaaaacctaccagcagaag
gttaaccggaggctgcagctggagcaagaaatggccaaagctggactctgtgaagctgag
caggagcagatgcggaagatcctctaccagaaagagtctaattacaacaggttaaagagg
gccaagatggacaagtctatgtttgtcaagatcaaaaccctggggatcggtgcctttgga
gaagtgtgccttgcttgtaaggtggacactcacgccctgtacgccatgaagaccctaagg
aaaaaggatgtcctgaaccggaatcaggtggcccacgtcaaggccgagagggacatcctg
gccgaggcagacaatgagtgggtggtcaaactctactactccttccaagacaaagacagc
ctgtactttgtgatggactacatccctggtggggacatgatgagcctgctgatccggatg
gaggtcttccctgagcacctggcccggttctacatcgcagagctgactttggccattgag
agtgtccacaagatgggcttcatccaccgagacatcaagcctgataacattttgatagat
ctggatggtcacattaaactcacagatttcggcctctgcactgggttcaggtggactcac
aattccaaatattaccagaaagggagccatgtcagacaggacagcatggagcccagcgac
ctctgggatgatgtgtctaactgtcggtgtggggacaggctgaagaccctagagcagagg
gcgcggaagcagcaccagaggtgcctggcacattcactggtggggactccaaactacatc
gcacccgaggtgctcctccgcaaagggtacactcaactctgtgactggtggagtgttgga
gtgattctcttcgagatgctggtggggcagccgccctttttggcacctactcccacagaa
acccagctgaaggtgatcaactgggagaacacgctccacattccagcccaggtgaagctg
agccctgaggccagggacctcatcaccaagctgtgctgctccgcagaccaccgcctgggg
cggaatggggccgatgacctgaaggcccaccccttcttcagcgccattgacttctccagt
gacatccggaagcagccagccccctacgttcccaccatcagccaccccatggacacctcg
aatttcgaccccgtagatgaagaaagcccttggaacgatgccagcgaaggtagcaccaag
gcctgggacacactcacctcgcccaataacaagcatcctgagcacgcattttacgaattc
accttccgaaggttctttgatgacaatggctacccctttcgatgcccaaagccttcagga
gcagaagcttcacaggctgagagctcagatttagaaagctctgatctggtggatcagact
gaaggctgccagcctgtgtacgtgtag
Homo sapiens (human): 9113
Help
Entry
9113 CDS
T01001
Symbol
LATS1, WARTS, wts
Name
(RefSeq) large tumor suppressor kinase 1
KO
K08791
serine/threonine-protein kinase LATS1/2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04390
Hippo signaling pathway
hsa04392
Hippo signaling pathway - multiple species
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04390 Hippo signaling pathway
9113 (LATS1)
04392 Hippo signaling pathway - multiple species
9113 (LATS1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
9113 (LATS1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
9113 (LATS1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
NDR family
9113 (LATS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
UBA
UBA_7
ABC1
Pkinase_C
Haspin_kinase
APH
Cas_Cas6_C
EcoEI_R_C
Kinase-like
UBA_3
Motif
Other DBs
NCBI-GeneID:
9113
NCBI-ProteinID:
NP_004681
OMIM:
603473
HGNC:
6514
Ensembl:
ENSG00000131023
UniProt:
O95835
Structure
PDB
LinkDB
All DBs
Position
6:complement(149658153..149718101)
Genome browser
AA seq
1130 aa
AA seq
DB search
MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE
DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVI
QALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKG
SKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPP
QVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGY
PPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQ
NVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNME
LYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQ
PSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNV
TVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENV
DSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHR
KKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVC
LARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYF
VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG
HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR
QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
KVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLR
QQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTF
RRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atgaagaggagtgaaaagccagaaggatatagacaaatgaggcctaagacctttcctgcc
agtaactatactgtcagtagccggcaaatgttacaagaaattcgggaatcccttaggaat
ttatctaaaccatctgatgctgctaaggctgagcataacatgagtaaaatgtcaaccgaa
gatcctcgacaagtcagaaatccacccaaatttgggacgcatcataaagccttgcaggaa
attcgaaactctctgcttccatttgcaaatgaaacaaattcttctcggagtacttcagaa
gttaatccacaaatgcttcaagacttgcaagctgctggatttgatgaggatatggttata
caagctcttcagaaaactaacaacagaagtatagaagcagcaattgaattcattagtaaa
atgagttaccaagatcctcgacgagagcagatggctgcagcagctgccagacctattaat
gccagcatgaaaccagggaatgtgcagcaatcagttaaccgcaaacagagctggaaaggt
tctaaagaatccttagttcctcagaggcatggcccgccactaggagaaagtgtggcctat
cattctgagagtcccaactcacagacagatgtaggaagacctttgtctggatctggtata
tcagcatttgttcaagctcaccctagcaacggacagagagtgaaccccccaccaccacct
caagtaaggagtgttactcctccaccacctccaagaggccagactccccctccaagaggt
acaactccacctcccccttcatgggaaccaaactctcaaacaaagcgctattctggaaac
atggaatacgtaatctcccgaatctctcctgtcccacctggggcatggcaagagggctat
cctccaccacctctcaacacttcccccatgaatcctcctaatcaaggacagagaggcatt
agttctgttcctgttggcagacaaccaatcatcatgcagagttctagcaaatttaacttt
ccatcagggagacctggaatgcagaatggtactggacaaactgatttcatgatacaccaa
aatgttgtccctgctggcactgtgaatcggcagccaccacctccatatcctctgacagca
gctaatggacaaagcccttctgctttacaaacagggggatctgctgctccttcgtcatat
acaaatggaagtattcctcagtctatgatggtgccaaacagaaatagtcataacatggaa
ctatataacattagtgtacctggactgcaaacaaattggcctcagtcatcttctgctcca
gcccagtcatccccgagcagtgggcatgaaatccctacatggcaacctaacataccagtg
aggtcaaattcttttaataacccattaggaaatagagcaagtcactctgctaattctcag
ccttctgctacaacagtcactgcaattacaccagctcctattcaacagcctgtgaaaagt
atgcgtgtattaaaaccagagctacagactgctttagcacctacacacccttcttggata
ccacagccaattcaaactgttcaacccagtccttttcctgagggaaccgcttcaaatgtg
actgtgatgccacctgttgctgaagctccaaactatcaaggaccaccaccaccctaccca
aaacatctgctgcaccaaaacccatctgttcctccatacgagtcaatcagtaagcctagc
aaagaggatcagccaagcttgcccaaggaagatgagagtgaaaagagttatgaaaatgtt
gatagtggggataaagaaaagaaacagattacaacttcacctattactgttaggaaaaac
aagaaagatgaagagcgaagggaatctcgtattcaaagttattctcctcaagcatttaaa
ttctttatggagcaacatgtagaaaatgtactcaaatctcatcagcagcgtctacatcgt
aaaaaacaattagagaatgaaatgatgcgggttggattatctcaagatgcccaggatcaa
atgagaaagatgctttgccaaaaagaatctaattacatccgtcttaaaagggctaaaatg
gacaagtctatgtttgtgaagataaagacactaggaataggagcatttggtgaagtctgt
ctagcaagaaaagtagatactaaggctttgtatgcaacaaaaactcttcgaaagaaagat
gttcttcttcgaaatcaagtcgctcatgttaaggctgagagagatatcctggctgaagct
gacaatgaatgggtagttcgtctatattattcattccaagataaggacaatttatacttt
gtaatggactacattcctgggggtgatatgatgagcctattaattagaatgggcatcttt
ccagaaagtctggcacgattctacatagcagaacttacctgtgcagttgaaagtgttcat
aaaatgggttttattcatagagatattaaacctgataatattttgattgatcgtgatggt
catattaaattgactgactttggcctctgcactggcttcagatggacacacgattctaag
tactatcagagtggtgaccatccacggcaagatagcatggatttcagtaatgaatggggg
gatccctcaagctgtcgatgtggagacagactgaagccattagagcggagagctgcacgc
cagcaccagcgatgtctagcacattctttggttgggactcccaattatattgcacctgaa
gtgttgctacgaacaggatacacacagttgtgtgattggtggagtgttggtgttattctt
tttgaaatgttggtgggacaacctcctttcttggcacaaacaccattagaaacacaaatg
aaggttatcaactggcaaacatctcttcacattccaccacaagctaaactcagtcctgaa
gcttctgatcttattattaaactttgccgaggacccgaagatcgcttaggcaagaatggt
gctgatgaaataaaagctcatccattttttaaaacaattgacttctccagtgacctgaga
cagcagtctgcttcatacattcctaaaatcacacacccaacagatacatcaaattttgat
cctgttgatcctgataaattatggagtgatgataacgaggaagaaaatgtaaatgacact
ctcaatggatggtataaaaatggaaagcatcctgaacatgcattctatgaatttaccttc
cgaaggttttttgatgacaatggctacccatataattatccgaagcctattgaatatgaa
tacattaattcacaaggctcagagcagcagtcggatgaagatgatcaaaacacaggctca
gagattaaaaatcgcgatctagtatatgtttaa
DBGET
integrated database retrieval system
