Homo sapiens (human): 27161
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Entry
27161 CDS
T01001
Symbol
AGO2, CASC7, EIF2C2, LESKRES, LINC00980, PPD, Q10
Name
(RefSeq) argonaute RISC catalytic component 2
KO
K11593
eukaryotic translation initiation factor 2C
Organism
hsa
Homo sapiens (human)
Disease
H02651
Lessel-Kreienkamp syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
27161 (AGO2)
03036 Chromosome and associated proteins [BR:
hsa03036
]
27161 (AGO2)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
27161 (AGO2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Gene silencing
RISC (RNA-induced silencing complex)
27161 (AGO2)
RNA interference (RNAi) pathway
RITS (RNA-induced transcriptional silencing) complex
27161 (AGO2)
microRNA pathway
RISC loading complex
27161 (AGO2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Piwi
ArgoN
ArgoMid
PAZ
ArgoL1
ArgoL2
Motif
Other DBs
NCBI-GeneID:
27161
NCBI-ProteinID:
NP_036286
OMIM:
606229
HGNC:
3263
Ensembl:
ENSG00000123908
UniProt:
Q9UKV8
Structure
PDB
PDBj
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All DBs
Position
8:complement(140520156..140642313)
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AA seq
859 aa
AA seq
DB search
MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ
ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
ALAKAVQVHQDTLRTMYFA
NT seq
2580 nt
NT seq
+upstream
nt +downstream
nt
atgtactcgggagccggccccgcacttgcacctcctgcgccgccgccccccatccaagga
tatgccttcaagcctccacctagacccgactttgggacctccgggagaacaatcaaatta
caggccaatttcttcgaaatggacatccccaaaattgacatctatcattatgaattggat
atcaagccagagaagtgcccgaggagagttaacagggaaatcgtggaacacatggtccag
cactttaaaacacagatctttggggatcggaagcccgtgtttgacggcaggaagaatcta
tacacagccatgccccttccgattgggagggacaaggtggagctggaggtcacgctgcca
ggagaaggcaaggatcgcatcttcaaggtgtccatcaagtgggtgtcctgcgtgagcttg
caggcgttacacgatgcactttcagggcggctgcccagcgtcccttttgagacgatccag
gccctggacgtggtcatgaggcacttgccatccatgaggtacacccccgtgggccgctcc
ttcttcaccgcgtccgaaggctgctctaaccctcttggcgggggccgagaagtgtggttt
ggcttccatcagtccgtccggccttctctctggaaaatgatgctgaatattgatgtgtca
gcaacagcgttttacaaggcacagccagtaatcgagtttgtttgtgaagttttggatttt
aaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaa
gaaattaaaggtctaaaggtggagataacgcactgtgggcagatgaagaggaagtaccgc
gtctgcaatgtgacccggcggcccgccagtcaccaaacattcccgctgcagcaggagagc
gggcagacggtggagtgcacggtggcccagtatttcaaggacaggcacaagttggttctg
cgctacccccacctcccatgtttacaagtcggacaggagcagaaacacacctaccttccc
ctggaggtctgtaacattgtggcaggacaaagatgtattaaaaaattaacggacaatcag
acctcaaccatgatcagagcgactgctaggtcggcgcccgatcggcaagaagagattagc
aaattgatgcgaagtgcaagtttcaacacagatccatacgtccgtgaatttggaatcatg
gtcaaagatgagatgacagacgtgactgggcgggtgctgcagccgccctccatcctctac
gggggcaggaataaagctattgcgacccctgtccagggcgtctgggacatgcggaacaag
cagttccacacgggcatcgagatcaaggtgtgggccattgcgtgcttcgccccccagcgc
cagtgcacggaagtccatctgaagtccttcacagagcagctcagaaagatctcgagagac
gccggcatgcccatccagggccagccgtgcttctgcaaatacgcgcagggggcggacagc
gtggagcccatgttccggcacctgaagaacacgtatgcgggcctgcagctggtggtggtc
atcctgcccggcaagacgcccgtgtacgccgaggtcaagcgcgtgggagacacggtgctg
gggatggccacgcagtgcgtgcagatgaagaacgtgcagaggaccacgccacagaccctg
tccaacctctgcctgaagatcaacgtcaagctgggaggcgtgaacaacatcctgctgccc
cagggcaggccgccggtgttccagcagcccgtcatctttctgggagcagacgtcactcac
ccccccgccggggatgggaagaagccctccattgccgccgtggtgggcagcatggacgcc
caccccaatcgctactgcgccaccgtgcgcgtgcagcagcaccggcaggagatcatacaa
gacctggccgccatggtccgcgagctcctcatccagttctacaagtccacgcgcttcaag
cccacccgcatcatcttctaccgcgacggtgtctctgaaggccagttccagcaggttctc
caccacgagttgctggccatccgtgaggcctgtatcaagctagaaaaagactaccagccc
gggatcaccttcatcgtggtgcagaagaggcaccacacccggctcttctgcactgacaag
aacgagcgggttgggaaaagtggaaacattccagcaggcacgactgtggacacgaaaatc
acccaccccaccgagttcgacttctacctgtgtagtcacgctggcatccaggggacaagc
aggccttcgcactatcacgtcctctgggacgacaatcgtttctcctctgatgagctgcag
atcctaacctaccagctgtgtcacacctacgtgcgctgcacacgctccgtgtccatccca
gcgccagcatactacgctcacctggtggccttccgggccaggtaccacctggtggataag
gaacatgacagtgctgaaggaagccatacctctgggcagagtaacgggcgagaccaccaa
gcactggccaaggcggtccaggttcaccaagacactctgcgcaccatgtactttgcttga
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