Homo sapiens (human): 27301
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Entry
27301 CDS
T01001
Symbol
APEX2, APE2, APEXL2, XTH2, ZGRF2
Name
(RefSeq) apurinic/apyrimidinic endodeoxyribonuclease 2
KO
K10772
AP endonuclease 2 [EC:
3.1.11.2
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
27301 (APEX2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.11 Exodeoxyribonucleases producing 5'-phosphomonoesters
3.1.11.2 exodeoxyribonuclease III
27301 (APEX2)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
AP endonucleases
27301 (APEX2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Exo_endo_phos
Zn_ribbon_GRF
Exo_endo_phos_2
Motif
Other DBs
NCBI-GeneID:
27301
NCBI-ProteinID:
NP_055296
OMIM:
300773
HGNC:
17889
Ensembl:
ENSG00000169188
UniProt:
Q9UBZ4
E5KN95
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All DBs
Position
X:55000363..55009057
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AA seq
518 aa
AA seq
DB search
MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPL
AIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFT
QEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQI
RAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHV
GPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVM
GSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHN
NQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSA
LMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRT
VKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgttgcgcgtggtgagctggaacatcaatgggattcggagacccctgcaaggggtggca
aatcaggaacccagcaactgtgccgccgtggccgtggggcgcattttggacgagctggat
gcggatatcgtctgtctccaggaaaccaaagtgaccagggatgcactgacagagcccctg
gctatcgttgagggttataactcctatttcagcttcagccgcaaccgtagcggctattct
ggtgtagccaccttctgtaaggacaatgctaccccagtggctgctgaagaaggcctgagt
ggcctgtttgccacccagaatggggatgttggttgctatggaaacatggatgagtttacc
caagaggaactccgggctctggatagtgagggcagggccctcctcacacagcataagatc
cgcacatgggaaggtaaggagaagaccttgaccctaatcaacgtgtactgcccccatgcg
gaccctgggaggcctgagcggctagtctttaagatgcgcttctatcgtttgctgcaaatc
cgagcagaagccctcctggcggcaggcagccatgtgatcattctgggtgacctgaataca
gcccaccgccccattgaccactgggatgcagtcaacctggaatgctttgaagaggaccca
gggcgcaagtggatggacagcttgctcagtaacttggggtgccagtctgcctctcatgta
gggcccttcatcgatagctaccgctgcttccaaccaaagcaggagggggccttcacctgc
tggtcagcagtcactggcgcccgccatctcaactatggctcccggcttgactatgtgctg
ggggacaggaccctggtcatagacacctttcaggcctctttcctgctgcctgaggtgatg
ggctctgaccactgccctgtgggtgcagtcttgagtgtgtcctctgtgcctgcaaaacag
tgcccacctctgtgcacccgcttcctccctgagtttgcaggcacccagctcaagatcctt
cgcttcctagttcctctcgaacaaagtcctgtgttggagcagtcgacgctgcagcacaac
aatcaaacccgggtacagacatgccaaaacaaagcccaagtgcgctcaaccaggcctcag
cccagtcaggttggctctagcagaggccagaaaaacctgaagagctactttcagccctcc
cctagctgtccccaagcctctcctgacatagagctgcctagcctaccactgatgagcgcc
ctcatgaccccgaagactccagaagagaaggcagtggccaaagtggtgaaggggcaggcc
aagacttcagaagccaaagatgagaaggagttacggacctcattctggaagtctgtgctg
gcggggcccttgcgcacacccctctgtgggggccacagggagccatgtgtgatgcgtact
gtgaagaagccaggacccaacttgggccgccgcttctacatgtgtgccaggccccggggt
cctcccactgacccctcctcccggtgcaacttcttcctctggagcaggcccagctga
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