Homo sapiens (human): 2746 Help Entry 2746              CDS       T01001                                  Symbol GLUD1, GDH, GDH1, GLUD, hGDH1 Name (RefSeq) glutamate dehydrogenase 1   KO K00261   glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] Organism hsa  Homo sapiens (human) Pathway hsa00220   Arginine biosynthesis hsa00250   Alanine, aspartate and glutamate metabolism hsa00910   Nitrogen metabolism hsa01100   Metabolic pathways hsa01200   Carbon metabolism hsa04217   Necroptosis hsa04964   Proximal tubule bicarbonate reclamation Disease H01267   Familial hyperinsulinemic hypoglycemia H01400   Secondary hyperammonemia Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09102 Energy metabolism    00910 Nitrogen metabolism     2746 (GLUD1)   09105 Amino acid metabolism    00250 Alanine, aspartate and glutamate metabolism     2746 (GLUD1)    00220 Arginine biosynthesis     2746 (GLUD1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     2746 (GLUD1)  09150 Organismal Systems   09155 Excretory system    04964 Proximal tubule bicarbonate reclamation     2746 (GLUD1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     2746 (GLUD1) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.4  Acting on the CH-NH2 group of donors    1.4.1  With NAD+ or NADP+ as acceptor     1.4.1.3  glutamate dehydrogenase [NAD(P)+]      2746 (GLUD1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of breast cancer cells    2746 (GLUD1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ELFV_dehydrog ELFV_dehydrog_N 2-Hacid_dh_C Motif Other DBs NCBI-GeneID:  2746 NCBI-ProteinID:  NP_005262 OMIM:  138130 HGNC:  4335 Ensembl:  ENSG00000148672 UniProt:  P00367 E9KL48 Structure PDBPDBj LinkDB All DBs Position 10:complement(87050202..87094843) Genome browser AA seq 558 aa AA seqDB search MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV NAIEKVFKVYNEAGVTFT NT seq 1677 nt NT seq  +upstreamnt  +downstreamnt atgtaccgctacctgggcgaagcgctgttgctgtcccgggccgggcccgctgccctgggc tcggcgtccgccgactcggccgcgttgctgggctgggcccggggacagcccgccgccgcc ccgcagccggggctggcattggccgcccggcgccactacagcgaggcggtggccgaccgc gaggacgaccccaacttcttcaagatggtggagggcttcttcgatcgcggcgccagcatc gtggaggacaagctggtggaggacctgaggacccgggagagcgaggagcagaagcggaac cgggtgcgcggcatcctgcggatcatcaagccctgcaaccatgtgctgagtctctccttc cccatccggcgcgacgacggctcctgggaggtcatcgaaggctaccgggcccagcacagc cagcaccgcacgccctgcaagggaggtatccgttacagcactgatgtgagtgtagatgaa gtaaaagctttggcttctctgatgacatacaagtgtgcagtggttgatgtgccgtttggg ggtgctaaagctggtgttaagatcaatcccaagaactatactgataatgaattggaaaag atcacaaggaggttcaccatggagctagcaaaaaagggctttattggtcctggcattgat gtgcctgctccagacatgagcacaggtgagcgggagatgtcctggatcgctgatacctat gccagcaccatagggcactatgatattaatgcacacgcctgtgttactggtaaacccatc agccaagggggaatccatggacgcatctctgctactggccgtggtgtcttccatgggatt gaaaatttcatcaatgaagcttcttacatgagcattttaggaatgacaccagggtttgga gataaaacatttgttgttcagggatttggtaatgtgggcctacactctatgagatattta catcgttttggtgctaaatgtattgctgttggtgagtctgatgggagtatatggaatcca gatggtattgacccaaaggaactggaagacttcaaattgcaacatgggtccattctgggc ttccccaaggcaaagccctatgaaggaagcatcttggaggccgactgtgacatactgatc ccagctgccagtgagaagcagttgaccaaatccaacgcacccagagtcaaagccaagatc attgctgaaggtgccaatgggccaacaactccagaagctgacaagatcttcctggagaga aacattatggttattccagatctctacttgaatgctggaggagtgacagtatcttacttt gagtggctgaagaatctaaatcatgtcagctatggccgtttgaccttcaaatatgaaagg gattctaactaccacttgctcatgtctgttcaagagagtttagaaagaaaatttggaaag catggtggaactattcccattgtacccacggcagagttccaagacaggatatcgggtgca tctgagaaagacatcgtgcactctggcttggcatacacaatggagcgttctgccaggcaa attatgcgcacagccatgaagtataacctgggattggacctgagaacagctgcctatgtt aatgccattgagaaagtcttcaaagtgtacaatgaagctggtgtgaccttcacatag

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