Homo sapiens (human): 2889
Help
Entry
2889 CDS
T01001
Symbol
RAPGEF1, C3G, GRF2
Name
(RefSeq) Rap guanine nucleotide exchange factor 1
KO
K06277
Rap guanine nucleotide exchange factor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04015
Rap1 signaling pathway
hsa04510
Focal adhesion
hsa04722
Neurotrophin signaling pathway
hsa04910
Insulin signaling pathway
hsa05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
2889 (RAPGEF1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
2889 (RAPGEF1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
2889 (RAPGEF1)
09156 Nervous system
04722 Neurotrophin signaling pathway
2889 (RAPGEF1)
09160 Human Diseases
09162 Cancer: specific types
05211 Renal cell carcinoma
2889 (RAPGEF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
Motif
Other DBs
NCBI-GeneID:
2889
NCBI-ProteinID:
NP_005303
OMIM:
600303
HGNC:
4568
Ensembl:
ENSG00000107263
UniProt:
Q13905
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(131576775..131740076)
Genome browser
AA seq
1077 aa
AA seq
DB search
MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEG
YPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKV
LEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSE
DKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDRE
VEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRV
AVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKS
DEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGE
SGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYER
HPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKP
PPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVD
SVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQ
SEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFL
TTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILK
LLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFH
SHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQ
EKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTL
IDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILD
SMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
NT seq
3234 nt
NT seq
+upstream
nt +downstream
nt
atggacacagactctcagcgttctcatctctcttccttcaccatgaagctgatggacaaa
ttccactcacccaaaatcaagagaacgccatcaaagaagggaaaaccagctgaggtgtcc
gtaaagattccagagaagcctgtgaacaaagaggcaacagacagatttctaccagagggc
taccctctccccttggatctggagcagcaggcagtagaatttatgtccaccagtgctgtg
gcttccaggtctcaaaggcagaagaacctgagctggctggaggagaaagagaaggaagtt
gtcagtgccctgcgctactttaagaccattgtggacaaaatggcaattgataagaaggta
ctggagatgcttccagggtcagccagcaaggtgctggaggccatcttacccctggtgcag
aacgatcctcgaattcagcacagctcagccctctcttcctgctatagccgagtgtaccaa
agcctcgccaacctcattcgctggtctgaccaagtgatgctggaaggcgtgaactcagaa
gacaaggagatggtgacgactgtgaagggggtcatcaaggctgtgctggatggagtgaag
gagctggtcaggctcaccatcgagaagcagggacgtccgtctccgacgagccccgtgaag
cccagttcccctgccagcaagcctgatggcccagcagagctccccctgacagaccgcgag
gtagagatcctaaacaagacgactgggatgtcacagtcaactgagctcctcccagatgcc
acggatgaagaggtcgcgccccccaagcctcctctgcctggcattcgggtggttgataat
agtcctccaccagcattgccacccaagaaaagacagtcggcgccgtcccctacccgagtg
gctgtggtggcccccatgagccgagccaccagtggctccagtttgcctgttggaatcaat
aggcaggattttgatgttgactgttacgcacagaggcgactgtcaggaggcagccactca
tatggtggagagtcgccccgcctctccccctgcagcagcataggcaagctcagcaagtca
gacgagcagctgtcctctctggacagggacagtgggcagtgctcccggaacacaagctgt
gaaacactagaccactatgatcccgactatgaattcctccagcaagacctctctaacgca
gaccagatacctcagcagacggcctggaaccttagcccgttgccagagtctttgggggag
tctgggtctccatttcttggccctcctttccagctgcctcttggcggccatccccagcca
gacggacctctggccccagggcagcagacagatacgccacctgctctccccgagaagaag
cgcaggagcgcagcctcccagacggcggacggctctggctgcagggtgtcctacgagcgg
catccctcgcagtatgacaacatctctggggaggacctgcagagcacagccccgatccca
tccgtcccctacgcgccctttgctgctattctgccctttcagcatggaggttcctcagcc
cctgtcgaatttgtgggtgattttactgctcctgagtcaaccggtgacccagaaaaacca
cctcctctaccagagaagaaaaacaaacacatgctggcctacatgcagttgctggaggac
tactcggagccgcagccctctatgttctaccagacgccacagaacgagcacatctaccag
cagaagaacaagctcctcatggaggtatacggcttcagcgactccttcagtggggtggac
tccgtgcaggagctggccccgccgcccgccctaccccccaagcagcggcagctggagcca
ccggctgggaaagacggacatcccagagatccctcagcggtcagcggcgtccctgggaag
gacagcagagacggcagtgagagggccccaaagtcaccagatgctctggagtcggctcag
tcggaggaggaagtggacgagctgtccctcattgaccacaacgaaattatgtccaggctg
acgctcaagcaggagggtgatgacgggccggacgtccgcggaggatctggggacatctta
ctggtccatgctactgagactgacaggaaagatttggtgttgtactgcgaggcattcctg
accacctacaggaccttcatctccccagaggagctcatcaagaagctgcagtacagatat
gagaaattctctccctttgccgacacattcaagaagcgcgtcagcaagaacacgttcttc
gtgctggtacgggtggtggatgagctctgcctggtggagttgacagaagagatcctgaag
ctgctgatggaactggtcttccgcctggtgtgcaatggggagctgagcctggcccgtgtg
ctccggaagaacatcctggacaaggtggaccagaagaagctactcaggtgtgccacctcc
agccagcccctggcagcccggggggtagcagccaggccggggaccttgcacgactttcac
agccatgagatagcggagcagctaacgctgctggatgctgagctcttctataaaatagag
attcctgaggttttgctttgggcaaaagagcagaatgaggagaagagccccaacttgacc
cagttcacggagcacttcaacaacatgtcctactgggtccggtccataatcatgttacag
gaaaaggcccaggacagggaacggctgctcttgaagttcatcaagatcatgaagcacttg
cggaagctgaataacttcaactcctacttggccatcctctctgccctggactcggcgccc
atccgcaggctggagtggcagaagcagacttcagagggcctggccgagtactgcacactg
atcgacagctcgtcctccttccgagcctaccgggccgccctctcggaggtggaaccgccg
tgcatcccgtacctggggctgatcctgcaggacctgaccttcgttcacctgggaaaccca
gactacatcgacgggaaagtgaacttctccaagcggtggcagcagttcaacatcctcgac
agcatgcgctgcttccagcaggcgcactatgacatgcggaggaacgacgacattataaac
ttcttcaatgacttcagtgaccacctggctgaggaggccctatgggaactgtctctgaaa
attaaacccaggaacataacaaggagaaaaacagaccgggaagagaagacctag
DBGET
integrated database retrieval system
