Homo sapiens (human): 29102
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Entry
29102 CDS
T01001
Symbol
DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L, RNASEN
Name
(RefSeq) drosha ribonuclease III
KO
K03685
ribonuclease III [EC:
3.1.26.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03008
Ribosome biogenesis in eukaryotes
hsa05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03008 Ribosome biogenesis in eukaryotes
29102 (DROSHA)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
29102 (DROSHA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
29102 (DROSHA)
03009 Ribosome biogenesis [BR:
hsa03009
]
29102 (DROSHA)
03036 Chromosome and associated proteins [BR:
hsa03036
]
29102 (DROSHA)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.26 Endoribonucleases producing 5'-phosphomonoesters
3.1.26.3 ribonuclease III
29102 (DROSHA)
Messenger RNA biogenesis [BR:
hsa03019
]
Prokaryotic type
Bacterial mRNA degradation factors
RNA degradosome components
Ribonucreases
29102 (DROSHA)
Ribosome biogenesis [BR:
hsa03009
]
Eukaryotic type
90S particles
RNase
29102 (DROSHA)
Prokaryotic type
rRNA processing factors
29102 (DROSHA)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Gene silencing
microRNA pathway
Microprocessor complex
29102 (DROSHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ribonuclease_3
Ribonucleas_3_3
dsrm
RM44_endonuclase
YcaO
Motif
Other DBs
NCBI-GeneID:
29102
NCBI-ProteinID:
NP_037367
OMIM:
608828
HGNC:
17904
Ensembl:
ENSG00000113360
Pharos:
Q9NRR4
(Tbio)
UniProt:
Q9NRR4
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:complement(31400494..31532093)
Genome browser
AA seq
1374 aa
AA seq
DB search
MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgatgcagggaaacacatgtcacagaatgtcgttccacccgggacgagggtgtccccga
ggacgaggaggacatggagccagaccctcagcaccatcctttaggccccaaaatctgagg
ctgcttcaccctcagcagcctcctgtgcaatatcaatatgaacctccaagtgccccttcc
accactttctcaaactctccagcccccaattttctccctccacgaccagactttgtaccc
ttccccccacccatgcctccgtcagcgcaaggccctcttcccccctgcccaatcaggccg
cctttccccaaccaccagatgaggcaccccttcccagttcctccttgttttcctcccatg
ccaccaccaatgccttgtcctaataaccccccagtccctggggcacctcctggacaaggc
actttccccttcatgatgccccctccctccatgcctcatcccccgccccctccagtcatg
ccgcagcaggttaattatcagtaccctccgggctattctcaccacaacttcccacctccc
agttttaatagtttccagaacaaccctagttctttcctgcccagtgctaataacagcagt
agtcctcatttcagacatctccctccatacccactcccaaaggctcccagtgagagaagg
tccccagaaaggctgaaacactatgatgaccacaggcaccgagatcacagtcatgggcga
ggtgagaggcatcggtccctggatcggcgggagcgaggccgcagtcccgacaggagaaga
caagacagccggtacagatctgattatgaccgagggagaacaccatctcgccaccgcagc
tacgaacggagcagagagcgagaacgggagagacacaggcatcgagacaaccgaagatca
ccatctctggaaaggtcctacaaaaaagagtataagagatctggaaggagttacggttta
tcggttgttcctgaacctgctggatgcacaccagaattacctggggagattattaaaaat
acagattcttgggccccacccctggagattgtgaatcatcgctccccaagtagggagaag
aagagagctcgttgggaggaagaaaaagaccgttggagtgacaaccagagttctggcaaa
gacaagaactatacctcaatcaaggaaaaagagcccgaggagaccatgcctgacaagaat
gaggaggaagaagaagaacttcttaagcctgtgtggattcgatgcactcattcagaaaac
tactactccagtgaccccatggatcaggtgggagattctacagtggttggaacgagtagg
cttcgtgacttatatgacaaatttgaggaggagttggggagcaggcaagaaaaggccaaa
gctgctcggcctccgtgggaacctccaaagacgaagctcgatgaagatttagagagttcc
agtgaatccgagtgtgagtctgatgaggacagcacctgttctagcagctcagactctgaa
gtttttgacgttattgcagaaatcaaacgcaaaaaggcccaccctgaccgacttcatgat
gaactttggtacaacgatccaggccagatgaatgatggaccactctgcaaatgcagcgca
aaggcaagacgcacaggaattaggcacagcatttatcctggagaagaggccatcaagccc
tgtcgtcctatgaccaacaatgctggcagacttttccactaccggatcacagtctccccg
cctacgaactttttaactgacaggccaactgttatagaatacgatgatcacgagtatatc
tttgaaggattttctatgtttgcacatgcccccctgaccaatattccactgtgtaaagta
attagattcaacatagactacacgattcatttcattgaagagatgatgccggagaatttt
tgtgtgaaagggcttgaactcttttcactgttcctattcagagatattttggaattatat
gactggaatcttaaaggtcctttgtttgaagacagccctccctgctgcccaagatttcat
ttcatgccacgttttgtaagatttcttccagatggaggaaaggaagtgctgtccatgcac
cagattctcctgtacttgttaaggtgcagcaaagccctggtgcctgaggaggagattgcc
aatatgcttcagtgggaggagctggagtggcagaaatatgcagaagaatgcaaaggcatg
attgttaccaaccctgggacgaaaccaagctctgtccgtatcgatcaactggatcgtgaa
cagttcaaccccgatgtgattacttttccgattatcgtccactttgggatacgccctgca
cagttgagttatgcaggagacccacagtaccaaaaactgtggaagagttatgtgaaactt
cgccacctcctagcaaatagtcccaaagtcaaacaaactgacaaacagaagctggcacag
agggaggaagccctccaaaaaatacggcagaagaatacaatgagacgagaagtaacggtg
gagctaagtagccaaggattctggaaaactggcatccgttctgatgtctgtcagcatgca
atgatgctacctgttctgacccatcatatccgctaccaccaatgcctaatgcatttggac
aagttgataggatatactttccaagatcgttgtctgttgcagctggccatgactcatcca
agtcatcatttaaattttggaatgaatcctgatcatgccaggaattcattatctaactgt
ggaattcggcagcccaaatacggagacagaaaagttcatcacatgcacatgcggaagaaa
gggattaacaccttgataaatatcatgtcacgccttggccaagatgacccaactccctcg
aggattaaccacaatgaacggttggaattcctgggtgatgctgttgttgaatttctgacc
agcgtccatttgtactatttgtttcctagtctggaagaaggaggattagcaacctatcgg
actgccattgttcagaatcagcaccttgccatgctagcaaagaaacttgaactggatcga
tttatgctgtatgctcacgggcctgacctttgtagagaatcggaccttcgacatgcaatg
gccaattgttttgaagcgttaataggagctgtttacttggagggaagcctggaggaagcc
aagcagttatttggacgcttgctctttaatgatccggacctgcgcgaagtctggctcaat
tatcctctccacccactccaactacaagagccaaatactgatcgacaacttattgaaact
tctccagttctacaaaaacttactgagtttgaagaagcaattggagtaatttttactcat
gttcgacttctggcaagggcattcacattgagaactgtgggatttaaccatctgacccta
ggccacaatcagagaatggaattcctaggtgactccataatgcaactggtagccacagag
tacttattcattcatttcccagatcatcatgaaggacacttaactttgttgcgaagctct
ttggtgaataatagaactcaggccaaggtagcggaggagctgggcatgcaggagtacgcc
ataaccaacgacaagaccaagaggcctgtggcgcttcgcaccaagaccttggcggacctt
ttggaatcatttattgcagcgctgtacattgataaggatttggaatatgttcatactttc
atgaatgtctgcttctttccacgattgaaagagttcattttgaatcaggattggaatgac
cccaaatcccagcttcagcagtgttgcttgacacttaggacagaaggaaaagagccagac
attcctctgtacaagactctgcagacagtgggcccatcccatgcccgaacctacactgtg
gctgtttatttcaagggagaaagaataggctgtgggaaaggaccaagtattcagcaagcg
gaaatgggagcagcaatggatgcgcttgaaaaatataattttccccagatggcccatcag
aagcggttcatcgaacggaagtacagacaagagttaaaagaaatgaggtgggaaagagag
catcaagagagagagccagatgagactgaagacatcaagaaataa
DBGET
integrated database retrieval system
