Homo sapiens (human): 29953
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Entry
29953 CDS
T01001
Symbol
TRHDE, PAP-II, PGPEP2, TRH-DE
Name
(RefSeq) thyrotropin releasing hormone degrading enzyme
KO
K01306
pyroglutamyl-peptidase II [EC:
3.4.19.6
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
29953 (TRHDE)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.6 pyroglutamyl-peptidase II
29953 (TRHDE)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M1
29953 (TRHDE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M1
ERAP1_C
Peptidase_M1_N
Ferlin_C
Motif
Other DBs
NCBI-GeneID:
29953
NCBI-ProteinID:
NP_037513
OMIM:
606950
HGNC:
30748
Ensembl:
ENSG00000072657
UniProt:
Q9UKU6
LinkDB
All DBs
Position
12:72087266..72670758
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AA seq
1069 aa
AA seq
DB search
MALDGELGEQEEEKKKKKKKKRKKKKEEEEEEEGAEKSSSPFAAAMGEDDAALRAGSRGL
SDPWADSVGVRPRTTERHIAVHKRLVLAFAVSLVALLAVTMLAVLLSLRFDECGASATPG
ADGGPSGFPERGGNGSLPGSARRNHHAGGDSWQPEAGGVASPGTTSAQPPSEEEREPWEP
WTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQLA
EDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVL
HGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDG
WVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKR
LIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVT
MVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHE
VMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLT
IHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIIT
QQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDK
GSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQ
NIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWP
KNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDI
VYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVL
DQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGEL
KELKNFMKNYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH
NT seq
3210 nt
NT seq
+upstream
nt +downstream
nt
atggccctggacggcgagctgggggagcaagaggaggagaagaaaaagaagaagaaaaag
aagaggaagaagaagaaggaggaggaggaggaggaggagggggccgagaagagcagctca
cccttcgcagccgcgatgggggaagacgacgccgcgcttcgggctggcagcagggggctc
tccgacccgtgggcagactcagtgggagtgcgaccccgcaccacggagcgccacatcgcc
gtacacaagcggcttgtgctggccttcgctgtgtccctcgtggcattgctcgcggtcaca
atgctcgctgtgctgctcagcctgcgcttcgacgagtgcggggcgagtgccacgccaggc
gccgacggtggcccctcaggctttccggagcgcggcggcaacgggagcctccctggatcg
gcccggcgcaaccaccacgcaggcggggactcctggcagcccgaggcgggtggggtggcc
agtccggggaccacgtcggcccagccgccgtcggaggaggagcgggagccgtgggagccg
tggacgcagctgcgcctgtcgggccacctgaagccgctgcactacaatctgatgctcacc
gccttcatggagaacttcaccttctccggggaggtcaacgtggagatcgcgtgccggaac
gccacccgctacgtagtgctgcacgcttcccgagtggcggtggagaaagtgcagctggcc
gaggaccgggcgttcggggctgtccctgtagccggttttttcctctacccgcaaacccag
gtcttagtggtggtgctgaataggacactggacgcgcagaggaattacaatctgaagatt
atctacaacgcgctcatcgagaatgagctcctgggcttcttccgcagctcctatgtgctc
cacggggagagaagattccttggtgttactcagttttcgcctacacatgccagaaaggca
tttccttgttttgatgagccaatctacaaggctactttcaaaatcagcatcaagcatcaa
gcaacctatttatctttatctaatatgccagtggaaacttccgtgtttgaggaagatgga
tgggttacggatcacttttcacagacccctctcatgtccacatattatttagcctgggca
atttgcaacttcacatacagagaaactaccaccaagagtggggttgtagtacgattatat
gcaagacctgatgctatcagaagaggatccggggactatgctctccatataacaaagaga
ttaatagaattttatgaagactactttaaagtgccctattccttgccaaaactagatctt
ttagctgtgcctaagcatccgtatgctgctatggagaactggggactaagtatttttgtg
gaacaaagaatactgctggatcccagtgtttcatctatttcttatttgctggatgtcacc
atggtcattgttcatgagatatgtcaccagtggtttggtgaccttgtgacgcctgtgtgg
tgggaagacgtgtggctgaaggaagggtttgctcactactttgaatttgttggtacagac
tacctctatcctggctggaacatggaaaagcagaggtttctgaccgatgttctgcatgaa
gtgatgctgctggacggtttggccagttcccatccagtatcacaggaagtgctgcaggca
acagatattgacagggtgtttgactggatcgcatataaaaagggtgctgctttaataaga
atgctggctaattttatgggccattcagttttccagaggggtttgcaagattatttaacc
attcataagtatggtaatgcagccagaaatgatctctggaatacattatcggaggcttta
aaaagaaatgggaaatatgtaaatatacaagaagtaatggatcagtggacactccagatg
ggttatcctgttatcaccatcttgggaaacacaacagcagaaaatagaataataattacc
caacagcattttatctatgatatcagtgctaaaactaaagcacttaaacttcagaataac
agttacctgtggcagattccattaactattgtggtaggaaatagaagccatgtgtcttca
gaagcaattatttgggtgtctaacaaatcagagcaccacagaataacttatttggacaaa
ggaagctggctgctggggaacatcaatcaaactggctattttagagtcaactatgaccta
aggaactggagattattaattgatcaattaatccggaatcatgaggttctttctgtcagt
aaccgagcgggcttgatcgatgatgccttcagcctagccagggctggctatttgcctcag
aatattcctctggagattatcagatacctgtctgaggagaaggattttcttccttggcat
gctgccagccgagctctttatcctctagataaattactggaccgcatggaaaactacaac
attttcaatgaatatattttaaagcaagttgcaacaacatatatcaagcttgggtggccg
aaaaataattttaatggatctcttgttcaagcatcctaccaacatgaagaactacgtaga
gaagttataatgctggcctgcagttttggcaacaagcactgtcaccaacaggcatcaaca
cttatttcagattggatttccagcaacaggaacagaataccactaaatgttagagacatc
gtatactgtacaggagtgtcactactggatgaggatgtctgggaattcatatggatgaaa
ttccattccaccacagcagtttctgagaagaaaatattattggaagccttaacttgcagt
gatgacaggaatttattaaacaggcttctaaatctgtcactgaattctgaggtggtgctg
gatcaagatgcaattgatgtcataatccatgtagctcgaaatccacatggtcgagacctt
gcctggaagtttttcagggataaatggaagatattaaataccaggtatggagaagcattg
tttatgaattccaaactcatcagtggtgtcacagaatttcttaatactgaaggtgaactc
aaagagctcaagaacttcatgaaaaactatgatggggtagctgctgcttctttctcacga
gctgtggaaactgtcgaagccaatgtgcgctggaaaatgctttaccaagacgagcttttc
caatggttaggaaaagctctaagacactaa
DBGET
integrated database retrieval system
