Homo sapiens (human): 30061
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Entry
30061 CDS
T01001
Symbol
SLC40A1, FPN, FPN1, HFE4, IREG1, MST079, MSTP079, MTP1, SLC11A3
Name
(RefSeq) solute carrier family 40 member 1
KO
K14685
solute carrier family 40 (iron-regulated transporter), member 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04081
Hormone signaling
hsa04216
Ferroptosis
hsa04978
Mineral absorption
Network
nt06525
Ferroptosis
Element
N01591
Fe2+ Ferroportin transport
Disease
H00211
Hemochromatosis
Drug target
Vamifeport (
DG03215
):
D12289
D12290
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04081 Hormone signaling
30061 (SLC40A1)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
30061 (SLC40A1)
09150 Organismal Systems
09154 Digestive system
04978 Mineral absorption
30061 (SLC40A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
30061 (SLC40A1)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC40: Basolateral iron transporter
30061 (SLC40A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FPN1
DUF347
Motif
Other DBs
NCBI-GeneID:
30061
NCBI-ProteinID:
NP_055400
OMIM:
604653
HGNC:
10909
Ensembl:
ENSG00000138449
UniProt:
Q9NP59
Structure
PDB
PDBj
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All DBs
Position
2:complement(189560590..189580786)
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AA seq
571 aa
AA seq
DB search
MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL
TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL
LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI
DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK
EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV
SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF
TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP
TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL
QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR
FAQNTLGNKLFACGPDAKEVRKENQANTSVV
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggcgggagatcacaaccgccagagaggatgctgtggatccttggccgactac
ctgacctctgcaaaattccttctctaccttggtcattctctctctacttggggagatcgg
atgtggcactttgcggtgtctgtgtttctggtagagctctatggaaacagcctccttttg
acagcagtctacgggctggtggtggcagggtctgttctggtcctgggagccatcatcggt
gactgggtggacaagaatgctagacttaaagtggcccagacctcgctggtggtacagaat
gtttcagtcatcctgtgtggaatcatcctgatgatggttttcttacataaacatgagctt
ctgaccatgtaccatggatgggttctcacttcctgctatatcctgatcatcactattgca
aatattgcaaatttggccagtactgctactgcaatcacaatccaaagggattggattgtt
gttgttgcaggagaagacagaagcaaactagcaaatatgaatgccacaatacgaaggatt
gaccagttaaccaacatcttagcccccatggctgttggccagattatgacatttggctcc
ccagtcatcggctgtggctttatttcgggatggaacttggtatccatgtgcgtggagtac
gttctgctctggaaggtttaccagaaaaccccagctctagctgtgaaagctggtcttaaa
gaagaggaaactgaattgaaacagctgaatttacacaaagatactgagccaaaacccctg
gagggaactcatctaatgggtgtgaaagactctaacatccatgagcttgaacatgagcaa
gagcctacttgtgcctcccagatggctgagcccttccgtaccttccgagatggatgggtc
tcctactacaaccagcctgtgtttctggctggcatgggtcttgctttcctttatatgact
gtcctgggctttgactgcatcaccacagggtacgcctacactcagggactgagtggttcc
atcctcagtattttgatgggagcatcagctataactggaataatgggaactgtagctttt
acttggctacgtcgaaaatgtggtttggttcggacaggtctgatctcaggattggcacag
ctttcctgtttgatcttgtgtgtgatctctgtattcatgcctggaagccccctggacttg
tccgtttctccttttgaagatatccgatcaaggttcattcaaggagagtcaattacacct
accaagatacctgaaattacaactgaaatatacatgtctaatgggtctaattctgctaat
attgtcccggagacaagtcctgaatctgtgcccataatctctgtcagtctgctgtttgca
ggcgtcattgctgctagaatcggtctttggtcctttgatttaactgtgacacagttgctg
caagaaaatgtaattgaatctgaaagaggcattataaatggtgtacagaactccatgaac
tatcttcttgatcttctgcatttcatcatggtcatcctggctccaaatcctgaagctttt
ggcttgctcgtattgatttcagtctcctttgtggcaatgggccacattatgtatttccga
tttgcccaaaatactctgggaaacaagctctttgcttgcggtcctgatgcaaaagaagtt
aggaaggaaaatcaagcaaatacatctgttgtttga
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