Homo sapiens (human): 3249
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Entry
3249 CDS
T01001
Symbol
HPN, TMPRSS1
Name
(RefSeq) hepsin
KO
K08665
hepsin [EC:
3.4.21.106
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
3249 (HPN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
3249 (HPN)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.106 hepsin
3249 (HPN)
Peptidases and inhibitors [BR:
hsa01002
]
Serine peptidases
Family S1: chymotrypsin family
3249 (HPN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin
Hepsin-SRCR
SRCR_2
DUF1986
Trypsin_2
Motif
Other DBs
NCBI-GeneID:
3249
NCBI-ProteinID:
NP_002142
OMIM:
142440
HGNC:
5155
Ensembl:
ENSG00000105707
UniProt:
P05981
A0A140VJK9
Structure
PDB
PDBj
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All DBs
Position
19:35040506..35066573
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AA seq
417 aa
AA seq
DB search
MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSAD
ARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCV
DEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSL
RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYH
GGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ
YYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCE
DSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
NT seq
1254 nt
NT seq
+upstream
nt +downstream
nt
atggcgcagaaggagggtggccggactgtgccatgctgctccagacccaaggtggcagct
ctcactgcggggaccctgctacttctgacagccatcggggcggcatcctgggccattgtg
gctgttctcctcaggagtgaccaggagccgctgtacccagtgcaggtcagctctgcggac
gctcggctcatggtctttgacaagacggaagggacgtggcggctgctgtgctcctcgcgc
tccaacgccagggtagccggactcagctgcgaggagatgggcttcctcagggcactgacc
cactccgagctggacgtgcgaacggcgggcgccaatggcacgtcgggcttcttctgtgtg
gacgaggggaggctgccccacacccagaggctgctggaggtcatctccgtgtgtgattgc
cccagaggccgtttcttggccgccatctgccaagactgtggccgcaggaagctgcccgtg
gaccgcatcgtgggaggccgggacaccagcttgggccggtggccgtggcaagtcagcctt
cgctatgatggagcacacctctgtgggggatccctgctctccggggactgggtgctgaca
gccgcccactgcttcccggagcggaaccgggtcctgtcccgatggcgagtgtttgccggt
gccgtggcccaggcctctccccacggtctgcagctgggggtgcaggctgtggtctaccac
gggggctatcttccctttcgggaccccaacagcgaggagaacagcaacgatattgccctg
gtccacctctccagtcccctgcccctcacagaatacatccagcctgtgtgcctcccagct
gccggccaggccctggtggatggcaagatctgtaccgtgacgggctggggcaacacgcag
tactatggccaacaggccggggtactccaggaggctcgagtccccataatcagcaatgat
gtctgcaatggcgctgacttctatggaaaccagatcaagcccaagatgttctgtgctggc
taccccgagggtggcattgatgcctgccagggcgacagcggtggtccctttgtgtgtgag
gacagcatctctcggacgccacgttggcggctgtgtggcattgtgagttggggcactggc
tgtgccctggcccagaagccaggcgtctacaccaaagtcagtgacttccgggagtggatc
ttccaggccataaagactcactccgaagccagcggcatggtgacccagctctga
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