KEGG   Homo sapiens (human): 3294
Entry
3294              CDS       T01001                                 
Symbol
HSD17B2, EDH17B2, HSD17, SDR9C2
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 2
  KO
K13368  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00140  Steroid hormone biosynthesis
hsa01100  Metabolic pathways
hsa04913  Ovarian steroidogenesis
Module
hsa_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Network
nt06019  Steroid hormone biosynthesis
  Element
N01541  Testosterone biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    3294 (HSD17B2)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    3294 (HSD17B2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     3294 (HSD17B2)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     3294 (HSD17B2)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Ins_allergen_rp Epimerase DUF6056
Other DBs
NCBI-GeneID: 3294
NCBI-ProteinID: NP_002144
OMIM: 109685
HGNC: 5211
Ensembl: ENSG00000086696
UniProt: P37059
LinkDB
Position
16:82035253..82098534
AA seq 387 aa
MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLIL
FSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPG
AEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL
LMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVT
MFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI
LAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYD
YFAKRHFGQDKPMPRALRMPNYKKKAT
NT seq 1164 nt   +upstreamnt  +downstreamnt
atgagcactttcttctcggacacagcatggatctgcctggctgtccccacagtactatgt
gggacagtattttgcaaatacaagaagagctcagggcagctgtggagctggatggtctgc
ctggcaggcctctgtgcagtctgcctgctcatcctgtcccctttttggggcttgatcctc
ttctcggtgtcatgcttcctcatgtatacttacttatctggccaagaattgttacctgtg
gatcagaaggcagtcctggtgacaggtggtgattgcgggcttggccatgctttgtgcaag
tatctggatgagctgggcttcacggtatttgccggagttttgaatgaaaatggcccagga
gctgaggaattgcgaagaacctgctctccgcgcctctcggtgctccaaatggacatcacg
aagccagtgcagataaaagatgcttacagcaaggttgcagcaatgctgcaggacagagga
ctgtgggctgtgatcaacaatgctggggtgcttggctttccaactgatggggagcttctt
cttatgactgactacaaacaatgcatggccgtgaacttctttggaactgtggaggtcaca
aagacgtttttgcctcttcttagaaaatccaaagggaggctggtgaatgtcagcagcatg
ggaggaggggccccaatggaaaggctggcatcttatggctcatcaaaggcggctgtgacc
atgttctcatcagttatgagactggagctttccaagtggggaattaaagttgcttccatc
caacctggaggcttcctaacaaatatcgcaggcaccagtgacaagtgggaaaagctggag
aaggacattctggaccacctccccgctgaggtacaggaagactacggccaggactacatc
ttagcacagcggaatttcctcctattgatcaactcgttagccagcaaggacttctctccg
gtgctgcgggacatccagcatgctatcttggcgaagagcccttttgcctattacacgcca
gggaaaggcgcttacttgtggatctgccttgctcactatttgcctattggcatatatgat
tactttgctaaaagacattttggccaagacaagcccatgcccagagctctaagaatgcct
aactacaagaaaaaggccacctag

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